EP0467965A4 - Plasmodium circumsporozoite protein analogs lacking repeat sequences - Google Patents

Plasmodium circumsporozoite protein analogs lacking repeat sequences

Info

Publication number
EP0467965A4
EP0467965A4 EP19900906626 EP90906626A EP0467965A4 EP 0467965 A4 EP0467965 A4 EP 0467965A4 EP 19900906626 EP19900906626 EP 19900906626 EP 90906626 A EP90906626 A EP 90906626A EP 0467965 A4 EP0467965 A4 EP 0467965A4
Authority
EP
European Patent Office
Prior art keywords
repeat sequences
circumsporozoite protein
protein analogs
analogs lacking
plasmodium circumsporozoite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19900906626
Other languages
English (en)
Other versions
EP0467965A1 (de
Inventor
Philip J. Barr
Ian C. Bathurst
Helen L. Gibson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of EP0467965A1 publication Critical patent/EP0467965A1/de
Publication of EP0467965A4 publication Critical patent/EP0467965A4/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C07K16/205—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP19900906626 1989-04-11 1990-04-11 Plasmodium circumsporozoite protein analogs lacking repeat sequences Pending EP0467965A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33628889A 1989-04-11 1989-04-11
US336288 1989-04-11

Publications (2)

Publication Number Publication Date
EP0467965A1 EP0467965A1 (de) 1992-01-29
EP0467965A4 true EP0467965A4 (en) 1992-04-15

Family

ID=23315419

Family Applications (2)

Application Number Title Priority Date Filing Date
EP19900906626 Pending EP0467965A4 (en) 1989-04-11 1990-04-11 Plasmodium circumsporozoite protein analogs lacking repeat sequences
EP19900303907 Withdrawn EP0392820A3 (de) 1989-04-11 1990-04-11 Plasmodium circumsporozoite Proteinanaloge ohne repetierte Sequenzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP19900303907 Withdrawn EP0392820A3 (de) 1989-04-11 1990-04-11 Plasmodium circumsporozoite Proteinanaloge ohne repetierte Sequenzen

Country Status (10)

Country Link
EP (2) EP0467965A4 (de)
JP (1) JPH04506064A (de)
AP (1) AP134A (de)
AU (1) AU635265B2 (de)
CA (1) CA2051432A1 (de)
IL (1) IL94063A0 (de)
NZ (1) NZ233255A (de)
PT (1) PT93721A (de)
WO (1) WO1990011775A1 (de)
ZA (1) ZA902741B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362623A (en) * 1991-06-14 1994-11-08 The John Hopkins University Sequence specific DNA binding by p53
DE19544233A1 (de) * 1995-11-28 1997-06-05 Hoechst Ag Verfahren zur Nutzung des Hefe-ADH II-Promotorsystems zur biotechnologischen Produktion heterologer Proteine in hohen Ausbeuten
WO2006088597A2 (en) 2005-01-18 2006-08-24 Walter Read Army Institute Of Research A plasmodium vivax hybrid circumsporozoite protein and vaccine
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166410A2 (de) * 1984-06-26 1986-01-02 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Immunologisch aktive Peptide, geeignet zur Einführung von Immunisierung gegen Malaria und deren Kodierung von Genen
EP0192626A1 (de) * 1985-02-07 1986-08-27 Smithkline Beecham Corporation Malaria-Impfstoff
WO1987000533A1 (en) * 1985-07-12 1987-01-29 New York University Immunogenic peptide antigen corresponding to plasmodium vivax circumsporozoite protein
EP0254862A1 (de) * 1986-06-26 1988-02-03 BEHRINGWERKE Aktiengesellschaft Impfstoffe gegen protozoischen Parasiten
WO1988007546A1 (en) * 1987-03-30 1988-10-06 New York University Immunogenic polypeptide and method for purifying it
EP0398540A1 (de) * 1989-05-03 1990-11-22 Smithkline Beecham Corporation Malariaimpfstoff
EP0432965A1 (de) * 1989-12-08 1991-06-19 Smithkline Beecham Corporation Malaria-Impfstoff

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1329124C (en) * 1987-02-02 1994-05-03 Jerald C. Sadoff Conjugate malaria vaccine
IT1223301B (it) * 1987-09-11 1990-09-19 Eniricerche Spa Polipeptidi sequenziali immunologicamente attivi
US5112749A (en) * 1987-10-02 1992-05-12 Praxis Biologics, Inc. Vaccines for the malaria circumsporozoite protein

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166410A2 (de) * 1984-06-26 1986-01-02 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Immunologisch aktive Peptide, geeignet zur Einführung von Immunisierung gegen Malaria und deren Kodierung von Genen
EP0192626A1 (de) * 1985-02-07 1986-08-27 Smithkline Beecham Corporation Malaria-Impfstoff
WO1987000533A1 (en) * 1985-07-12 1987-01-29 New York University Immunogenic peptide antigen corresponding to plasmodium vivax circumsporozoite protein
EP0254862A1 (de) * 1986-06-26 1988-02-03 BEHRINGWERKE Aktiengesellschaft Impfstoffe gegen protozoischen Parasiten
WO1988007546A1 (en) * 1987-03-30 1988-10-06 New York University Immunogenic polypeptide and method for purifying it
EP0398540A1 (de) * 1989-05-03 1990-11-22 Smithkline Beecham Corporation Malariaimpfstoff
EP0432965A1 (de) * 1989-12-08 1991-06-19 Smithkline Beecham Corporation Malaria-Impfstoff

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BIOTECHNOLOGY ABSTRACTS DATABASE accession no. 89-05065; P.J. ROMERO et al.: "Multiple T helper cell epitopes of the circumsporozoite protein of plasmodium berghei - Recombinant vaccine preparation; gene cloning and expression in saccharomyces cerevisiae" & Eur.J.Immunol. 1988, vol.18, no. 12, pages 1951-1957 *
See also references of WO9011775A1 *
THE JOURNAL OF BIOLOGICAL CHEMISTRY vol. 262, no. 25, 5 September 1987, pages 11935-11939, Baltimore, MD, US; V.F: DE LA CRUZ et al.: "Sequence Variation in Putative Functional Domains of the Circumsporozoite Protein of Plasmodium falciparum" *
TRENDS IN BIOTECHNOLOGY vol. 6, no. 3, March 1988, pages 63-68, Cambridge, GB; J.F. YOUNG et al.: "The prospects for a human malaria vaccine" *

Also Published As

Publication number Publication date
EP0467965A1 (de) 1992-01-29
JPH04506064A (ja) 1992-10-22
AP134A (en) 1991-07-16
CA2051432A1 (en) 1990-10-12
PT93721A (pt) 1990-11-20
EP0392820A3 (de) 1990-12-27
WO1990011775A1 (en) 1990-10-18
ZA902741B (en) 1991-03-27
NZ233255A (en) 1993-02-25
EP0392820A2 (de) 1990-10-17
AU5524290A (en) 1990-11-05
AP9000176A0 (en) 1990-04-30
IL94063A0 (en) 1991-01-31
AU635265B2 (en) 1993-03-18

Similar Documents

Publication Publication Date Title
GB2233861B (en) Sequence synchronisation
GB8910880D0 (en) Sequencing method
EP0356210A3 (en) Method of enhancing fabric rewettability
GR900100319A (en) Novel thieno-triazolo-diazepino-derivatives preparation method
IL89313A0 (en) Method for producing a recombinant protein derived from the circumsporozoite gene of plasmodium falciparum
EP0467965A4 (en) Plasmodium circumsporozoite protein analogs lacking repeat sequences
IL96579A0 (en) Malaria vaccine
SG119293G (en) Antigens of -1 (plasmodium falciparum)
GB8919064D0 (en) Plasmodium merozoite rhoptries antigen
YU237588A (en) Process for preparing plasmodium falciparum proteins
IL94257A0 (en) Malaria vaccine
IL78476A0 (en) Highly repetitive antigens of plasmodium falciparum
IE901300L (en) Plasmodium circumsporozoite protein analogues
EP0344257A4 (de) RHOPTRY ANTIGEN VON -i(PLASMODIUM FALCIPARUM).
GB8914984D0 (en) Nucleotide sequences
EP0425676A4 (en) Digitizing method
GB2228008B (en) Dna probes for plasmodium vivax
ATE144537T1 (de) Merozoit-oberflächen-plasmodium-falciparum- antigen
IE894106L (en) Expression of the plasmodium circumsporozite protein in¹insects
GB8924107D0 (en) Sequencing method
NZ221114A (en) Merozoite surface antigen of plasmodium falciparum
ZA875266B (en) Merozoite surface antigen of plasmodium falciparum
GB9000604D0 (en) Sequence synchronisation
DK376889D0 (da) Rhoptry-antigen fra plasmodium falciparum
EP0516721A4 (en) Antigenic proteins of plasmodium

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 19911022

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: GIBSON, HELEN, L.

Inventor name: BARR, PHILIP, J.

Inventor name: BATHURST, IAN, C.

A4 Supplementary search report drawn up and despatched

Effective date: 19920226

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE

XX Miscellaneous (additional remarks)

Free format text: VERFAHREN ABGESCHLOSSEN INFOLGE VERBINDUNG MIT 90303907.1/0392820 (EUROPAEISCHE ANMELDENUMMER/VEROEFFENTLICHUNGSNUMMER) VOM 14.09.92.