EP0644765A4 - Bindemittel enthaltende metallpulverzusammensetzungen für hochtemperaturverdichtung. - Google Patents

Bindemittel enthaltende metallpulverzusammensetzungen für hochtemperaturverdichtung.

Info

Publication number
EP0644765A4
EP0644765A4 EP93914110A EP93914110A EP0644765A4 EP 0644765 A4 EP0644765 A4 EP 0644765A4 EP 93914110 A EP93914110 A EP 93914110A EP 93914110 A EP93914110 A EP 93914110A EP 0644765 A4 EP0644765 A4 EP 0644765A4
Authority
EP
European Patent Office
Prior art keywords
high temperature
metal powder
compositions containing
powder compositions
temperature compression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93914110A
Other languages
English (en)
French (fr)
Other versions
EP0644765A1 (de
Inventor
Kevin D Cooper
Craig Hammerberg
Kameron W Maxwell
Ben Y Tseng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genta Inc
University of Michigan Ann Arbor
Original Assignee
Genta Inc
University of Michigan Ann Arbor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genta Inc, University of Michigan Ann Arbor filed Critical Genta Inc
Publication of EP0644765A1 publication Critical patent/EP0644765A1/de
Publication of EP0644765A4 publication Critical patent/EP0644765A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/15Nucleic acids forming more than 2 strands, e.g. TFOs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/31Chemical structure of the backbone
    • C12N2310/312Phosphonates
    • C12N2310/3125Methylphosphonates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
EP93914110A 1992-05-22 1993-05-21 Bindemittel enthaltende metallpulverzusammensetzungen für hochtemperaturverdichtung. Withdrawn EP0644765A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88773492A 1992-05-22 1992-05-22
US887734 1992-05-22
PCT/US1993/004917 WO1993024134A1 (en) 1992-05-22 1993-05-21 Treatment of cellular hyperproliferation by inhibition of interleukin-1

Publications (2)

Publication Number Publication Date
EP0644765A1 EP0644765A1 (de) 1995-03-29
EP0644765A4 true EP0644765A4 (de) 1997-02-26

Family

ID=25391751

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93914110A Withdrawn EP0644765A4 (de) 1992-05-22 1993-05-21 Bindemittel enthaltende metallpulverzusammensetzungen für hochtemperaturverdichtung.

Country Status (9)

Country Link
EP (1) EP0644765A4 (de)
JP (1) JPH07508977A (de)
KR (1) KR950701528A (de)
AU (1) AU4388993A (de)
CA (1) CA2136349A1 (de)
IL (1) IL105741A0 (de)
MX (1) MX9302951A (de)
NZ (1) NZ253509A (de)
WO (1) WO1993024134A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075222A (en) 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
US6858409B1 (en) 1988-05-27 2005-02-22 Amgen Inc. Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
US6159460A (en) * 1988-05-27 2000-12-12 Amgen Inc. Method for treating interleukin-1 mediated diseases
GB9405021D0 (en) * 1994-03-15 1994-04-27 Unilever Plc Skin treatment composition
JP4117904B2 (ja) 1996-03-01 2008-07-16 エーロスクレーン エッス.アー. C−c ckr−5,cc−ケモカインレセプタ、その誘導体及びこれらの利用
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
JP4166432B2 (ja) * 1997-07-10 2008-10-15 セラコス・インコーポレイテッド 腸又は膀胱の炎症性疾病の処置
WO2004100987A2 (en) * 2003-05-06 2004-11-25 Regeneron Pharmaceuticals, Inc. Methods of using il-1 antagonists to treat neointimal hyperplasia
US7960355B2 (en) 2003-05-23 2011-06-14 Isis Pharmaceuticals, Inc. Compositions and methods for the modulation of the expression of B7 protein
US7897582B2 (en) 2003-05-23 2011-03-01 Isis Pharmaceuticals, Inc. Oligonucleotide compositions and methods for the modulation of the expression of B7 protein
WO2006084145A2 (en) * 2005-02-02 2006-08-10 Regeneron Pharmaceuticals, Inc. Methods of using il-1 antagonists to reduce c-reactive protein
GB0607189D0 (en) * 2006-04-10 2006-05-17 Polybiomed Ltd interleukin IL 1ra composition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989006702A1 (en) * 1988-01-21 1989-07-27 Chemex Pharmaceuticals, Inc. Selective inhibition of gene expression by photoactivatable oligonucleotides
WO1991015226A1 (en) * 1990-04-09 1991-10-17 The American National Red Cross Rejuvenation compositions and methods for their use
WO1992021353A1 (en) * 1991-05-31 1992-12-10 Genta Incorporated Compositions and delivery systems for transdermal administration of neutral oligomers
WO1993005071A1 (en) * 1991-08-30 1993-03-18 Sterling Winthrop Inc. INTERLEUKIN 1β PROTEASE AND INTERLEUKIN 1β PROTEASE INHIBITORS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135917A (en) * 1990-07-12 1992-08-04 Nova Pharmaceutical Corporation Interleukin receptor expression inhibiting antisense oligonucleotides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989006702A1 (en) * 1988-01-21 1989-07-27 Chemex Pharmaceuticals, Inc. Selective inhibition of gene expression by photoactivatable oligonucleotides
WO1991015226A1 (en) * 1990-04-09 1991-10-17 The American National Red Cross Rejuvenation compositions and methods for their use
WO1992021353A1 (en) * 1991-05-31 1992-12-10 Genta Incorporated Compositions and delivery systems for transdermal administration of neutral oligomers
WO1993005071A1 (en) * 1991-08-30 1993-03-18 Sterling Winthrop Inc. INTERLEUKIN 1β PROTEASE AND INTERLEUKIN 1β PROTEASE INHIBITORS

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
AAPS (AMERICAN ASSOCIATION OF PHARMACEUTICAL SCIENTISTS) EIGHTH ANNUAL MEETING AND EXPOSITION, ORLANDO, FLORIDA, USA, NOVEMBER 14-18, 1993. *
HAMMERBERG, C. ET AL.: "Interleukin - 1 receptor antagonist in normal and psoriatic epidermis.", JOURNAL OF CLINICAL INVESTIGATION, (1992 AUG) 90 (2) 571-83., XP000615300 *
MANSON, J. ET AL.: "Modulation of interleukin 1beta gene expression using antisense phosphorothioate oligonucleotides", LYMPHOKINE RES. 9 (1990);35-42, XP002021245 *
MILLER, K. ET AL.: "In vitro transdermal flux and tissue distribution of interleukin 1-beta antisense methyl phosphonate oligonucleotide from topical formulations.", PHARMACEUTICAL RESEARCH (NEW YORK) 10 (10 SUPPL.). S252. ABSTRACT PDD7310, October 1993 (1993-10-01), XP002021246 *
See also references of WO9324134A1 *

Also Published As

Publication number Publication date
JPH07508977A (ja) 1995-10-05
WO1993024134A1 (en) 1993-12-09
KR950701528A (ko) 1995-04-28
EP0644765A1 (de) 1995-03-29
NZ253509A (en) 1999-09-29
CA2136349A1 (en) 1993-12-09
MX9302951A (es) 1994-07-29
AU4388993A (en) 1993-12-30
IL105741A0 (en) 1993-09-22

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