EP0644769A4 - Biologisch aktive peptide mit n-terminalen substitutionen. - Google Patents

Biologisch aktive peptide mit n-terminalen substitutionen.

Info

Publication number: EP0644769A4
Authority: EP; European Patent Office
Prior art keywords: biologically active; active peptides; terminal substitutions; substitutions; terminal
Prior art date: 1992-06-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP93915173A

Other languages

English (en)

French (fr)

Other versions

EP0644769A1 (de

Inventor

U Prasad Kari

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Magainin Pharmaceuticals Inc

Original Assignee

Magainin Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-01

Filing date

1993-05-27

Publication date

1995-08-09

1993-05-27 Application filed by Magainin Pharmaceuticals Inc filed Critical Magainin Pharmaceuticals Inc

1995-03-29 Publication of EP0644769A1 publication Critical patent/EP0644769A1/de

1995-08-09 Publication of EP0644769A4 publication Critical patent/EP0644769A4/de

Status Ceased legal-status Critical Current

Links

102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
238000006467 substitution reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/463—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Zoology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

EP93915173A 1992-06-01 1993-05-27 Biologisch aktive peptide mit n-terminalen substitutionen. Ceased EP0644769A4 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US89120192A	1992-06-01	1992-06-01
US891201		1992-06-01
PCT/US1993/005192 WO1993024138A1 (en)	1992-06-01	1993-05-27	Biologically active peptides having n-terminal substitutions

Publications (2)

Publication Number	Publication Date
EP0644769A1 EP0644769A1 (de)	1995-03-29
EP0644769A4 true EP0644769A4 (de)	1995-08-09

Family

ID=25397782

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP93915173A Ceased EP0644769A4 (de)	1992-06-01	1993-05-27	Biologisch aktive peptide mit n-terminalen substitutionen.

Country Status (5)

Country	Link
EP (1)	EP0644769A4 (de)
JP (1)	JPH08500818A (de)
AU (1)	AU674525B2 (de)
CA (1)	CA2137087A1 (de)
WO (1)	WO1993024138A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6348445B1 (en)	1992-06-01	2002-02-19	Magainin Pharmaceuticals, Inc.	Biologically active peptides with reduced toxicity in animals and a method for preparing same
US5654274A (en) *	1992-06-01	1997-08-05	Magainin Pharmaceuticals, Inc.	Biologically active peptides having N-terminal substitutions
US5593866A (en) *	1992-08-21	1997-01-14	The University Of British Columbia	Cationic peptides and method for production
US5856178A (en) *	1993-08-30	1999-01-05	Utah State University	DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same
AU693518B2 (en) *	1994-01-18	1998-07-02	Magainin Pharmaceuticals, Inc.	Ion-channel forming amphiphilic peptides having n-terminal modifications
US5589364A (en) *	1994-07-29	1996-12-31	Magainin Pharmaceuticals Inc.	Recombinant production of biologically active peptides and proteins
AU3512595A (en) *	1994-09-13	1996-03-29	Magainin Pharmaceuticals, Inc.	Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds
US6057291A (en)	1995-06-02	2000-05-02	University Of British Columbia	Antimicrobial cationic peptides
DE69637731D1 (de)	1995-08-23	2008-12-11	Univ British Columbia	Antimikrobielle kationische peptide und methoden zu ihrer identifizierung
CA2294518A1 (en) *	1997-07-15	1999-01-28	Magainin Pharmaceuticals Inc.	Biologically active peptides with reduced toxicity in animals and a method for preparing same
NL1008139C2 (nl)	1998-01-27	1999-07-28	Stichting Tech Wetenschapp	Antimicrobiële peptiden.
GB9818938D0 (en)	1998-08-28	1998-10-21	Alpharma As	Bioactive peptides
US8283315B2 (en)	1998-08-28	2012-10-09	Lytix Biopharma As	Inhibition of tumour growth
NL1010692C2 (nl) *	1998-12-01	2000-06-06	Stichting Tech Wetenschapp	Antivirale peptiden.
DE602004029173D1 (de) *	2003-10-10	2010-10-28	Novo Nordisk As	Il-21-derivate
US20060228331A1 (en)	2003-10-10	2006-10-12	Novo Nordisk A/S	IL-21 Derivatives and variants
AU2007310777A1 (en)	2006-10-26	2008-05-02	Novo Nordisk A/S	IL-21 variants
WO2009094634A1 (en)	2008-01-24	2009-07-30	Esperance Pharmaceuticals	Lytic domain fusion constructs and methods of making and using same
KR20210090298A (ko)	2012-10-30	2021-07-19	에스퍼란스 파마슈티컬스, 인코포레이티드	항체/약물 컨쥬게이트 및 이의 사용 방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992001462A1 (en) *	1990-07-19	1992-02-06	The Scripps Research Institute	Amphiphilic peptide compositions and analogues thereof
WO1992022317A1 (en) *	1991-06-12	1992-12-23	Magainin Pharmaceuticals, Inc.	Composition and treatment with biologically active peptides having c-terminal substitutions
WO1993005802A1 (en) *	1991-09-13	1993-04-01	Magainin Pharmaceuticals Inc.	Biologically active amphiphilic peptide compositions and uses therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07504152A (ja) *	1990-02-08	1995-05-11	マゲイニン　ファーマスーティカルズ，　インコーポレーテッド	生物活性ペプチドおよび標的細胞、ウイルス、あるいはウイルス感染細胞の成長を抑制する方法
EP0668770A1 (de) *	1991-04-24	1995-08-30	Warner-Lambert Company	Alpha-substituierte polypeptide und therapeutischer aktivität
AU2238192A (en) *	1991-06-27	1993-01-25	Du Pont Merck Pharmaceutical Company, The	Modified peptides transportable into the central nervous system

1993
- 1993-05-27 CA CA002137087A patent/CA2137087A1/en not_active Abandoned
- 1993-05-27 WO PCT/US1993/005192 patent/WO1993024138A1/en not_active Ceased
- 1993-05-27 EP EP93915173A patent/EP0644769A4/de not_active Ceased
- 1993-05-27 JP JP6500832A patent/JPH08500818A/ja active Pending
- 1993-05-27 AU AU45258/93A patent/AU674525B2/en not_active Ceased

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992001462A1 (en) *	1990-07-19	1992-02-06	The Scripps Research Institute	Amphiphilic peptide compositions and analogues thereof
WO1992022317A1 (en) *	1991-06-12	1992-12-23	Magainin Pharmaceuticals, Inc.	Composition and treatment with biologically active peptides having c-terminal substitutions
WO1993005802A1 (en) *	1991-09-13	1993-04-01	Magainin Pharmaceuticals Inc.	Biologically active amphiphilic peptide compositions and uses therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9324138A1 *

Also Published As

Publication number	Publication date
JPH08500818A (ja)	1996-01-30
EP0644769A1 (de)	1995-03-29
WO1993024138A1 (en)	1993-12-09
AU4525893A (en)	1993-12-30
CA2137087A1 (en)	1993-12-09
AU674525B2 (en)	1997-01-02

Legal Events

Date	Code	Title	Description
1995-02-10	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-03-29	17P	Request for examination filed	Effective date: 19941125
1995-03-29	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1995-08-09	A4	Supplementary search report drawn up and despatched
1995-08-09	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1998-05-20	17Q	First examination report despatched	Effective date: 19980401
1998-09-11	GRAG	Despatch of communication of intention to grant	Free format text: ORIGINAL CODE: EPIDOS AGRA
1999-08-06	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
1999-09-22	18R	Application refused	Effective date: 19990509

Publication	Publication Date	Title
GB2269176B (en)	1997-01-08	Peptides
ZA925737B (en)	1993-03-01	New isosteric peptides.
ZA928511B (en)	1994-05-04	Peptides
ZA93505B (en)	1993-08-25	Insecticidally effective peptides.
EP0578819A4 (de)	1994-10-12	Icam ähnliche proteine.
HU9502041D0 (en)	1995-09-28	New peptide
EP0577775A4 (de)	1995-01-11	Anti-thrombotische peptide und pseudopeptide.
IL109187A0 (en)	1994-06-24	Biologically active polypeptide fusion dimers
EP0684834A4 (de)	1996-09-25	Mikroemulsionen, die therapeutische peptide enthalten.
EP0684833A4 (de)	1996-09-11	Mikroemulsionen mit therapeutischen peptiden.
ZA944195B (en)	1995-02-08	Biologically active vasopressin analogues
ZA936692B (en)	1994-04-29	Physiologically active peptide composition
GB9414833D0 (en)	1994-09-14	Polypeptide
EP0646172A4 (de)	1997-07-02	Rekombinantes entomopoxvirus.
GB9325519D0 (en)	1994-02-16	Peptides
EP0663834A4 (de)	1996-01-24	Wachstumshormon freisetzende peptide.
EP0579611A4 (de)	1995-04-19	Peptide.
ZA934353B (en)	1994-01-13	Linear peptides.
EP0671931A4 (de)	1995-11-22	Haemoregulatorische peptide.
DE3869939D1 (de)	1992-05-14	Biologisch wirksame peptide.
AU6582694A (en)	1994-11-21	Biologically active peptides
EP0482605A3 (en)	1992-08-26	Htlv-ii derived peptide
EP0572122A3 (de)	1994-11-17	C-terminale modifizierte osteogene Wachstumpolypeptide.
ZA928001B (en)	1993-06-22	Recombitope peptides.
ZA965735B (en)	1998-01-05	Recombinant peptide.