EP0654997A4 - Compositions d'azaspiranes substituees et procedes de traitement du psoriasis a l'aide de ces dernieres. - Google Patents

Compositions d'azaspiranes substituees et procedes de traitement du psoriasis a l'aide de ces dernieres.

Info

Publication number
EP0654997A4
EP0654997A4 EP93920102A EP93920102A EP0654997A4 EP 0654997 A4 EP0654997 A4 EP 0654997A4 EP 93920102 A EP93920102 A EP 93920102A EP 93920102 A EP93920102 A EP 93920102A EP 0654997 A4 EP0654997 A4 EP 0654997A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
treating psoriasis
azaspiranes
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93920102A
Other languages
German (de)
English (en)
Other versions
EP0654997A1 (fr
Inventor
Alison Mary Badger
Don Edgar Griswold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0654997A1 publication Critical patent/EP0654997A1/fr
Publication of EP0654997A4 publication Critical patent/EP0654997A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Solid State Image Pick-Up Elements (AREA)
  • Junction Field-Effect Transistors (AREA)
EP93920102A 1992-08-13 1993-08-12 Compositions d'azaspiranes substituees et procedes de traitement du psoriasis a l'aide de ces dernieres. Withdrawn EP0654997A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9217121 1992-08-13
GB929217121A GB9217121D0 (en) 1992-08-13 1992-08-13 Methods
PCT/US1993/007699 WO1994004151A1 (fr) 1992-08-13 1993-08-12 Compositions d'azaspiranes substituees et procedes de traitement du psoriasis a l'aide de ces dernieres

Publications (2)

Publication Number Publication Date
EP0654997A1 EP0654997A1 (fr) 1995-05-31
EP0654997A4 true EP0654997A4 (fr) 1997-09-17

Family

ID=10720233

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93920102A Withdrawn EP0654997A4 (fr) 1992-08-13 1993-08-12 Compositions d'azaspiranes substituees et procedes de traitement du psoriasis a l'aide de ces dernieres.

Country Status (4)

Country Link
EP (1) EP0654997A4 (fr)
JP (1) JPH08500593A (fr)
GB (1) GB9217121D0 (fr)
WO (1) WO1994004151A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002229A1 (fr) * 1990-08-10 1992-02-20 Smithkline Beecham Corporation Compositions immunosuppressives
WO1992022294A1 (fr) * 1991-06-07 1992-12-23 Smithkline Beecham Corporation Azaspiranes immunomodulateurs
WO1994004150A1 (fr) * 1992-08-13 1994-03-03 Smithkline Beecham Corporation Procedes de traitement du psoriasis a l'aide d'azaspirannes substitues

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002229A1 (fr) * 1990-08-10 1992-02-20 Smithkline Beecham Corporation Compositions immunosuppressives
WO1992022294A1 (fr) * 1991-06-07 1992-12-23 Smithkline Beecham Corporation Azaspiranes immunomodulateurs
WO1994004150A1 (fr) * 1992-08-13 1994-03-03 Smithkline Beecham Corporation Procedes de traitement du psoriasis a l'aide d'azaspirannes substitues

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A.M. BADGER ET AL.: "INHIBITION OF ANIMAL MODELS OF AUTOIMMUNE DISEASE AND THE INDUCTION OF NON-SPECIFIC SUPPRESSOR CELLS BY SK&F 105685 AND RELATED AZASPIRANES", INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, vol. 11, no. 7, 1989, pages 839 - 846, XP000677549 *
D.N. SAUDER ET AL.: "SUPPRESSOR CELL FUNCTION IN PSORIASIS", ARCHIVES OF DERMATOLOGY, vol. 116, no. 1, 1980, pages 51 - 55, XP000677543 *
J.E.F. REYNOLDS: "MARTINDALE, THE EXTRA PHARMACOPOEIA", 1989, THE PHARMACEUTICAL PRESS, LONDON, XP002034973 *
R. ENGST ET AL.: "EVALUATION OF IMMUNOSUPPRESSIVE ACTING ANTIPSORIATIC AGENTS", Z. HAUTKR., vol. 66, no. S2, 1991, pages 55 - 60, XP000677526 *
See also references of WO9404151A1 *

Also Published As

Publication number Publication date
JPH08500593A (ja) 1996-01-23
WO1994004151A1 (fr) 1994-03-03
GB9217121D0 (en) 1992-09-23
EP0654997A1 (fr) 1995-05-31

Similar Documents

Publication Publication Date Title
ZA93811B (en) Methods of treating inflammatory dermatoses.
GB9208339D0 (en) Treatment composition
GB9119557D0 (en) Method of treating hair
EP0758196A4 (fr) Compositions et procedes de traitement de tumeurs
IL136110A0 (en) Methods and compositions for the treatment of psoriasis
EP0579453A3 (fr) Composition pour le traitement de maçonnerie et procédé.
AU8192691A (en) Method of treatment and compositions therefore
EP0366753A4 (fr) N-alkoxyalkylamides et compositions de traitement cosmetique a base de ceux-ci.
EP0627930A4 (fr) Composition et procede de traitement de l'hepatite b.
IL105217A0 (en) Method and composition for treating acne
GB2271579B (en) Treatment of wood
AU1919592A (en) Method of treating trichotillomania and onychophagia
GB9218027D0 (en) Novel method of treatment
AU3720293A (en) Method and compositions for treating acne
EP0654996A4 (fr) Procedes de traitement du psoriasis a l'aide d'azaspirannes substitues.
EP0654997A4 (fr) Compositions d'azaspiranes substituees et procedes de traitement du psoriasis a l'aide de ces dernieres.
ZA936166B (en) Methods of treating cancer
GB9202196D0 (en) Method of treatment
GB9317943D0 (en) Treatment of laminitis
AU4652393A (en) Plant treating composition and methods of making and using same
GB9201391D0 (en) Method of treatment
GB9218597D0 (en) Novel method of treatment
GB9317989D0 (en) Treatment of laminitis
ZA948930B (en) Treatment of compost
HK1012276A (en) Methods of treating psoriasis employing substituted azaspiranes

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19950213

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): BE CH DE FR GB IT LI NL

A4 Supplementary search report drawn up and despatched

Effective date: 19970801

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): BE CH DE FR GB IT LI NL

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19971201