EP0702715A4 - KLONIERUNG UND EXPRESSION DER CHONDROITINASE I- UND II-GENE AUS $i(P. VULGARIS) - Google Patents

KLONIERUNG UND EXPRESSION DER CHONDROITINASE I- UND II-GENE AUS $i(P. VULGARIS)

Info

Publication number
EP0702715A4
EP0702715A4 EP94916561A EP94916561A EP0702715A4 EP 0702715 A4 EP0702715 A4 EP 0702715A4 EP 94916561 A EP94916561 A EP 94916561A EP 94916561 A EP94916561 A EP 94916561A EP 0702715 A4 EP0702715 A4 EP 0702715A4
Authority
EP
European Patent Office
Prior art keywords
chondroitinase
vulgaris
cloning
genes
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94916561A
Other languages
English (en)
French (fr)
Other versions
EP0702715A1 (de
Inventor
Michael Joseph Ryan
Kiran Manohar Khandke
Bruce Clifford Tilley
Jason Arnold Lotvin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of EP0702715A1 publication Critical patent/EP0702715A1/de
Publication of EP0702715A4 publication Critical patent/EP0702715A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP94916561A 1993-04-23 1994-04-22 KLONIERUNG UND EXPRESSION DER CHONDROITINASE I- UND II-GENE AUS $i(P. VULGARIS) Withdrawn EP0702715A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5220693A 1993-04-23 1993-04-23
US5361593A 1993-04-23 1993-04-23
US53615 1993-04-23
US52206 1993-04-23
PCT/US1994/004495 WO1994025567A1 (en) 1993-04-23 1994-04-22 CLONING AND EXPRESSION OF THE CHONDROITINASE I AND II GENES FROM $i(P. VULGARIS)

Publications (2)

Publication Number Publication Date
EP0702715A1 EP0702715A1 (de) 1996-03-27
EP0702715A4 true EP0702715A4 (de) 2000-01-19

Family

ID=26730328

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94916561A Withdrawn EP0702715A4 (de) 1993-04-23 1994-04-22 KLONIERUNG UND EXPRESSION DER CHONDROITINASE I- UND II-GENE AUS $i(P. VULGARIS)

Country Status (5)

Country Link
EP (1) EP0702715A4 (de)
JP (1) JPH09500011A (de)
AU (1) AU697156B2 (de)
CA (1) CA2161125A1 (de)
WO (1) WO1994025567A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716617A (en) * 1994-04-22 1998-02-10 American Cyanamid Company Compositions of proteus vulgaris chondroitinase I and chondroitinase II
EP0833926A1 (de) * 1995-06-07 1998-04-08 American Cyanamid Company Herstellung von chondroitinase in rekombinanten proteus vulgaris stämmen
US5888798A (en) * 1995-06-07 1999-03-30 American Cyanamid Company Chondroitinase I and chondroitinase II producing mutants of P. vulgaris
EP1575548B1 (de) 2002-05-04 2011-03-09 Acorda Therapeutics, Inc. Zusammensetzungen und verfahren zur förderung des neuronalen wachstums
US7959914B2 (en) 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
AU2013201097B2 (en) * 2003-05-16 2016-03-31 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for treatment of cns
AU2004247025B8 (en) * 2003-05-16 2011-06-30 Acorda Therapeutics, Inc. Fusion proteins for the treatment of CNS
US7429375B2 (en) * 2003-05-16 2008-09-30 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for the treatment of CNS
US7507570B2 (en) 2004-03-10 2009-03-24 Massachusetts Institute Of Technology Recombinant chondroitinase ABC I and uses thereof
ES2411504T3 (es) 2004-05-18 2013-07-05 Acorda Therapeutics, Inc. Métodos de purificación de condroitinasa y formulaciones estables de la misma
WO2007038548A2 (en) 2005-09-26 2007-04-05 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
EP2450442B1 (de) 2006-10-10 2017-07-19 Acorda Therapeutics, Inc. Zusammensetzungen und verfahren zur verwendung von chondroitinase-abci-mutanten

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1067253A (en) * 1965-02-15 1967-05-03 Biorex Laboratories Ltd Process for the preparation of enzymes
EP0576294A2 (de) * 1992-06-26 1993-12-29 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Chondroitinase, Herstellungsverfahren und pharmazeutische Zusammensetzung
JPH0698769A (ja) * 1992-09-22 1994-04-12 Maruha Corp コンドロイチナーゼ及びその遺伝子
EP0613949A2 (de) * 1993-02-24 1994-09-07 Maruha Corporation Gen für Chondroitinase ABC und dessen Verwendungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2726275B2 (ja) * 1988-08-24 1998-03-11 生化学工業株式会社 グリコサミノグリカン分解酵素の精製法
JPH0822223B2 (ja) * 1988-12-19 1996-03-06 東洋紡績株式会社 ＰｖｕＩ制限エンドヌクレアーゼの製造方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1067253A (en) * 1965-02-15 1967-05-03 Biorex Laboratories Ltd Process for the preparation of enzymes
EP0576294A2 (de) * 1992-06-26 1993-12-29 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Chondroitinase, Herstellungsverfahren und pharmazeutische Zusammensetzung
JPH0698769A (ja) * 1992-09-22 1994-04-12 Maruha Corp コンドロイチナーゼ及びその遺伝子
EP0613949A2 (de) * 1993-02-24 1994-09-07 Maruha Corporation Gen für Chondroitinase ABC und dessen Verwendungen

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Derwent World Patents Index; AN 94-155922, XP002113502, "chondroitinase and its gene ..." *
See also references of WO9425567A1 *
TAKEGAWA, K. ET AL.: "Effect of mucopolysaccharides on chondroitinase production and rapid isolation of chondroitinase", TECH. BULL. FAC. AGR. KAGAWA UNIV., vol. 45, no. 2, 1993, pages 111 - 114, XP002113501 *

Also Published As

Publication number Publication date
CA2161125A1 (en) 1994-11-10
AU6818394A (en) 1994-11-21
WO1994025567A1 (en) 1994-11-10
AU697156B2 (en) 1998-10-01
JPH09500011A (ja) 1997-01-07
EP0702715A1 (de) 1996-03-27

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