EP0722326A4 - Hochsulfatierte maltooligossaccharide mit heparinähnlichen eigenschaften - Google Patents

Hochsulfatierte maltooligossaccharide mit heparinähnlichen eigenschaften

Info

Publication number
EP0722326A4
EP0722326A4 EP94931314A EP94931314A EP0722326A4 EP 0722326 A4 EP0722326 A4 EP 0722326A4 EP 94931314 A EP94931314 A EP 94931314A EP 94931314 A EP94931314 A EP 94931314A EP 0722326 A4 EP0722326 A4 EP 0722326A4
Authority
EP
European Patent Office
Prior art keywords
heparin
properties
highly sulfated
maltooligosaccharides
sulfated maltooligosaccharides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94931314A
Other languages
English (en)
French (fr)
Other versions
EP0722326A1 (de
Inventor
Peter Fugedi
David John Tyrrell
Robert James Tressler
Robert Joseph Stack
Masayuki Ishihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glycomed Inc
Original Assignee
Glycomed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycomed Inc filed Critical Glycomed Inc
Publication of EP0722326A1 publication Critical patent/EP0722326A1/de
Publication of EP0722326A4 publication Critical patent/EP0722326A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP94931314A 1993-10-07 1994-10-04 Hochsulfatierte maltooligossaccharide mit heparinähnlichen eigenschaften Withdrawn EP0722326A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13348393A 1993-10-07 1993-10-07
US133483 1993-10-07
PCT/US1994/011368 WO1995009637A1 (en) 1993-10-07 1994-10-04 Highly sulfated maltooligosaccharides with heparin-like properties

Publications (2)

Publication Number Publication Date
EP0722326A1 EP0722326A1 (de) 1996-07-24
EP0722326A4 true EP0722326A4 (de) 1999-10-06

Family

ID=22458825

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94931314A Withdrawn EP0722326A4 (de) 1993-10-07 1994-10-04 Hochsulfatierte maltooligossaccharide mit heparinähnlichen eigenschaften

Country Status (5)

Country Link
EP (1) EP0722326A4 (de)
JP (1) JPH09503510A (de)
AU (1) AU700451B2 (de)
CA (1) CA2171465A1 (de)
WO (1) WO1995009637A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN261895A0 (en) * 1995-04-28 1995-05-18 Australian National University, The Preparation and use of sulfated oligosaccharides
AUPO556297A0 (en) 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
AUPO888497A0 (en) * 1997-09-01 1997-09-25 Australian National University, The Use of sulfated oligosaccharides as inhibitors of cardiovascular disease
DE19747195A1 (de) * 1997-10-24 1999-04-29 Knoll Ag Verwendung von Glykosaminoglykanen zur Herstellung von pharmazeutischen Zubereitungen zur Behandlung von mit Diabetes assoziierten Augenkrankheiten
AU3837300A (en) * 1999-04-15 2000-11-02 Takara Shuzo Co., Ltd. Remedies
US6608042B2 (en) * 2000-03-28 2003-08-19 Aventis Pharma, S.A. Pharmaceutical compositions containing oligosaccharides, the novel oligosaccharides and preparation thereof
CZ307433B6 (cs) 2001-09-12 2018-08-22 Leadiant Biosciences Sa Deriváty částečně desulfátovaných glykosaminoglykanů jako inhibitory heparanázy mající antiangiogenní účinky a zabraňující antikoagulačnímu působení
CN103788141B (zh) * 2004-03-04 2016-08-17 普罗吉恩制药有限公司 硫酸化寡聚糖衍生物
CN100363373C (zh) * 2005-01-14 2008-01-23 庄茅 异麦芽低聚糖硫酸酯（imos）的制备方法
KR101646960B1 (ko) * 2007-10-16 2016-08-09 프로젠 피지500 시리즈 피티와이 리미티드 신규한 황산화된 올리고사카라이드 유도체
AU2013215237B2 (en) * 2012-01-30 2017-11-23 Baxalta GmbH Non-anticoagulant sulfated or sulfonated polysaccharides
WO2013147264A1 (ja) 2012-03-30 2013-10-03 味の素株式会社 硫酸化化合物を含む幹細胞増殖用培地
US11787783B2 (en) 2016-12-13 2023-10-17 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof
WO2018107200A1 (en) 2016-12-13 2018-06-21 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108713A (en) * 1980-02-01 1981-08-28 Nippon Kayaku Co Ltd Antitumor preparation
JPH03145496A (ja) * 1989-10-30 1991-06-20 Dainippon Ink & Chem Inc オリゴ糖誘導体
EP0479093A1 (de) * 1990-10-03 1992-04-08 F. Hoffmann-La Roche Ag Oligosaccharidderivate und deren Verwendung in Heilmitteln

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4021544A (en) * 1976-07-12 1977-05-03 American Cyanamid Company Complement inhibitors
US4066829A (en) * 1976-07-12 1978-01-03 American Cyanamid Company Malto-dextrin poly(H-)sulfates
US4435387A (en) * 1982-10-25 1984-03-06 American Cyanamid Company Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
JPS5951583A (ja) * 1983-06-15 1984-03-26 Nippon Telegr & Teleph Corp <Ntt> 半導体レ−ザ装置
US4470976A (en) * 1983-08-29 1984-09-11 American Cyanamid Company Poly-cation salt of 4-O-polyhexaose-thio-arylene sulfates
IL85145A (en) * 1987-01-23 1994-08-26 Univ Australian Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity
EP0338092A1 (de) * 1987-10-30 1989-10-25 Chugai Seiyaku Kabushiki Kaisha Anti-hiv-agens
JPH036457A (ja) * 1989-06-02 1991-01-11 Koyo Seiko Co Ltd 車輪回転速度検出器を備えた車軸用軸受装置
JP2792914B2 (ja) * 1989-06-02 1998-09-03 光洋精工株式会社 車輪回転速度検出器を備えた車軸用軸受装置

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108713A (en) * 1980-02-01 1981-08-28 Nippon Kayaku Co Ltd Antitumor preparation
JPH03145496A (ja) * 1989-10-30 1991-06-20 Dainippon Ink & Chem Inc オリゴ糖誘導体
EP0479093A1 (de) * 1990-10-03 1992-04-08 F. Hoffmann-La Roche Ag Oligosaccharidderivate und deren Verwendung in Heilmitteln

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 15, no. 361 (C - 867) 12 September 1991 (1991-09-12) *
PATENT ABSTRACTS OF JAPAN vol. 5, no. 184 (C - 80) 21 November 1981 (1981-11-21) *
See also references of WO9509637A1 *

Also Published As

Publication number Publication date
WO1995009637A1 (en) 1995-04-13
JPH09503510A (ja) 1997-04-08
EP0722326A1 (de) 1996-07-24
AU8013694A (en) 1995-05-01
CA2171465A1 (en) 1995-04-13
AU700451B2 (en) 1999-01-07

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