EP0793490A4 - Zusammensetzungen aus tocopherol und beta-karotin - Google Patents
Zusammensetzungen aus tocopherol und beta-karotinInfo
- Publication number
- EP0793490A4 EP0793490A4 EP95944647A EP95944647A EP0793490A4 EP 0793490 A4 EP0793490 A4 EP 0793490A4 EP 95944647 A EP95944647 A EP 95944647A EP 95944647 A EP95944647 A EP 95944647A EP 0793490 A4 EP0793490 A4 EP 0793490A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- carotene
- tocopherol
- beta
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 title 1
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 title 1
- 235000013734 beta-carotene Nutrition 0.000 title 1
- 239000011648 beta-carotene Substances 0.000 title 1
- 229960002747 betacarotene Drugs 0.000 title 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229960001295 tocopherol Drugs 0.000 title 1
- 229930003799 tocopherol Natural products 0.000 title 1
- 235000010384 tocopherol Nutrition 0.000 title 1
- 239000011732 tocopherol Substances 0.000 title 1
- 125000002640 tocopherol group Chemical group 0.000 title 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36161594A | 1994-12-22 | 1994-12-22 | |
| US361615 | 1994-12-22 | ||
| PCT/US1995/016769 WO1996019215A1 (en) | 1994-12-22 | 1995-12-22 | Compositions of tocopherol and beta-carotene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0793490A1 EP0793490A1 (de) | 1997-09-10 |
| EP0793490A4 true EP0793490A4 (de) | 1999-12-15 |
Family
ID=23422755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP95944647A Withdrawn EP0793490A4 (de) | 1994-12-22 | 1995-12-22 | Zusammensetzungen aus tocopherol und beta-karotin |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0793490A4 (de) |
| JP (1) | JPH10511355A (de) |
| AU (1) | AU702831B2 (de) |
| WO (1) | WO1996019215A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6329432B2 (en) | 1993-06-28 | 2001-12-11 | The Howard Foundation | Mesozeaxanthin formulations for treatment of retinal disorders |
| US6262109B1 (en) | 1995-12-22 | 2001-07-17 | Henkel Corporation | Methods of preventing and/or treating high serum levels of cholesterol and/or lipids |
| WO1996019217A1 (en) * | 1994-12-22 | 1996-06-27 | Henkel Corporation | Pharmaceutical compositions comprising lycopene |
| ATE355832T1 (de) * | 1995-06-07 | 2007-03-15 | Howard Foundation | Pharmazeutisch aktive karotenoide |
| DK0996431T3 (da) * | 1997-06-19 | 2004-04-26 | Lycored Natural Prod Ind Ltd | Synergistiske præparater af lycopen og E-vitamin til forebyggelse af LDL-oxidation |
| IL121112A (en) | 1997-06-19 | 2005-11-20 | Lycored Natural Prod Ind Ltd | Synergistic pharmaceutical or dietary compositionscomprising lycopene and vitamin e for preventing ldl oxidation |
| WO1999018814A1 (en) * | 1997-10-14 | 1999-04-22 | Quest International B.V. | Preparation for the enhancement of the antioxidant status of cells |
| DE19838636A1 (de) * | 1998-08-26 | 2000-03-02 | Basf Ag | Carotinoid-Formulierungen, enthaltend ein Gemisch aus beta-Carotin, Lycopin und Lutein |
| US6048891A (en) | 1998-12-17 | 2000-04-11 | Loma Linda University Medical Center | Use of γ-tocopherol and its oxidative metabolite LLU-α in the treatment of natriuretic disease |
| US6582721B1 (en) * | 1999-09-17 | 2003-06-24 | Alcon, Inc. | Stable carotene-xanthophyll beadlet compositions and methods of use |
| US6350776B1 (en) | 1999-09-20 | 2002-02-26 | Angelo Manfredo Azzi | Method of treating proliferative disease with lycopene and alpha-tocopherol |
| KR20060132688A (ko) * | 2004-02-10 | 2006-12-21 | 네스텍소시에테아노님 | 카로티노이드 화합물의 시스 이성질체 함유 조성물 및 방법 |
| DE102005012831A1 (de) * | 2005-03-17 | 2006-09-21 | Schrezenmeier, Jürgen, Prof. Dr. | Herstellung eines Arzneimittels zur Senkung des Risikofaktors der Artherosklerose und/oder Erhöhung der Insulinsensitivität |
| US20090214696A1 (en) * | 2005-04-13 | 2009-08-27 | Koutsos Elizabeth A | Lycopene Incorporation Into Egg Yolks |
| RU2438358C2 (ru) | 2006-08-08 | 2012-01-10 | Нестек С.А. | Устойчивые и биологически доступные композиции изомеров каротиноидов для кожи и волос |
| EP3401396A1 (de) * | 2012-10-03 | 2018-11-14 | Metabogen AB | Behandlung oder vorbeugung von atherosklerose mit beta-carotin |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2057463A1 (en) * | 1991-12-11 | 1993-06-12 | David Rowland | Vitamin/mineral composition |
| FR2714292A1 (fr) * | 1993-12-23 | 1995-06-30 | Synthelabo | Association d'acétylsalicylate de DL-lysine et de vitamine E. |
| EP0699437A1 (de) * | 1994-08-25 | 1996-03-06 | Prospa B.V. | Pharmazeutische Zubereitungen enthaltend mehrfach ungesättigte Fettsäuren zusammen mit antioxydativen Vitaminen und Provitaminen |
| WO1997006697A1 (en) * | 1995-08-21 | 1997-02-27 | Unilever N.V. | Antioxidant comprising food products |
-
1995
- 1995-12-22 EP EP95944647A patent/EP0793490A4/de not_active Withdrawn
- 1995-12-22 AU AU47419/96A patent/AU702831B2/en not_active Ceased
- 1995-12-22 JP JP8520012A patent/JPH10511355A/ja active Pending
- 1995-12-22 WO PCT/US1995/016769 patent/WO1996019215A1/en not_active Ceased
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2057463A1 (en) * | 1991-12-11 | 1993-06-12 | David Rowland | Vitamin/mineral composition |
| FR2714292A1 (fr) * | 1993-12-23 | 1995-06-30 | Synthelabo | Association d'acétylsalicylate de DL-lysine et de vitamine E. |
| EP0699437A1 (de) * | 1994-08-25 | 1996-03-06 | Prospa B.V. | Pharmazeutische Zubereitungen enthaltend mehrfach ungesättigte Fettsäuren zusammen mit antioxydativen Vitaminen und Provitaminen |
| WO1997006697A1 (en) * | 1995-08-21 | 1997-02-27 | Unilever N.V. | Antioxidant comprising food products |
Non-Patent Citations (7)
| Title |
|---|
| BRATTSAND R: "Actions of vitamins A and E and some nicotinic acid derivatives on plasma lipids and on lipid infiltration of aorta in cholesterol-fed rabbits.", ATHEROSCLEROSIS, (1975 JUL-AUG) 22 (1) 47-61., XP002119576 * |
| BUTTURINI U: "Vitamins E and A in vascular diseases.", ACTA VITAMINOLOGICA ET ENZYMOLOGICA, (1982) 4 (1-2) 15-9. REF: 20, XP002119577 * |
| JIALAL I ET AL: "Effect of combined supplementation with alpha- tocopherol, ascorbate, and beta carotene on low-density lipoprotein oxidation [see comments].", CIRCULATION, (1993 DEC) 88 (6) 2780-6., XP002119578 * |
| KNEKT P ET AL: "Antioxidant vitamin intake and coronary mortality in a longitudinal population study.", AMERICAN JOURNAL OF EPIDEMIOLOGY, (1994 JUN 15) 139 (12) 1180-9., XP002119579 * |
| MEYERS D G: "The prevention of atherosclerosis with antioxidant vitamins.", KANSAS MEDICINE, (1994 JUL) 95 (7) 170-1., XP002119575 * |
| See also references of WO9619215A1 * |
| SPIRT J J ET AL: "The use of vitamin A and E in different forms of atherosclerosis.", Z GES INN MED, (1962 MAY 15) 17 431-6., XP002119580 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0793490A1 (de) | 1997-09-10 |
| JPH10511355A (ja) | 1998-11-04 |
| WO1996019215A1 (en) | 1996-06-27 |
| AU702831B2 (en) | 1999-03-04 |
| AU4741996A (en) | 1996-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 19970703 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: HENKEL CORPORATION |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 19991104 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
| 17Q | First examination report despatched |
Effective date: 20000922 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20010403 |