EP0876145A4 - Taxanzusammensetzung und verfahren - Google Patents

Taxanzusammensetzung und verfahren

Info

Publication number
EP0876145A4
EP0876145A4 EP96943805A EP96943805A EP0876145A4 EP 0876145 A4 EP0876145 A4 EP 0876145A4 EP 96943805 A EP96943805 A EP 96943805A EP 96943805 A EP96943805 A EP 96943805A EP 0876145 A4 EP0876145 A4 EP 0876145A4
Authority
EP
European Patent Office
Prior art keywords
taxane composition
taxane
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP96943805A
Other languages
English (en)
French (fr)
Other versions
EP0876145A1 (de
Inventor
Bijan Almassian
William Choy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genelabs Technologies Inc
Original Assignee
Genelabs Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genelabs Technologies Inc filed Critical Genelabs Technologies Inc
Publication of EP0876145A1 publication Critical patent/EP0876145A1/de
Publication of EP0876145A4 publication Critical patent/EP0876145A4/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
EP96943805A 1995-12-21 1996-12-19 Taxanzusammensetzung und verfahren Ceased EP0876145A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57620495A 1995-12-21 1995-12-21
US576204 1995-12-21
PCT/US1996/020187 WO1997023208A1 (en) 1995-12-21 1996-12-19 Taxane composition and method

Publications (2)

Publication Number Publication Date
EP0876145A1 EP0876145A1 (de) 1998-11-11
EP0876145A4 true EP0876145A4 (de) 1999-04-21

Family

ID=24303400

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96943805A Ceased EP0876145A4 (de) 1995-12-21 1996-12-19 Taxanzusammensetzung und verfahren

Country Status (6)

Country Link
EP (1) EP0876145A4 (de)
KR (1) KR970032859A (de)
CN (1) CN1209059A (de)
AU (1) AU724842B2 (de)
CA (1) CA2240595A1 (de)
WO (1) WO1997023208A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6964946B1 (en) 1995-10-26 2005-11-15 Baker Norton Pharmaceuticals, Inc. Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same
US5922754A (en) * 1998-10-02 1999-07-13 Abbott Laboratories Pharmaceutical compositions containing paclitaxel
EP1479382A1 (de) * 1999-06-18 2004-11-24 IVAX Research, Inc. Taxane enthaltende orale Pharmazeutische Zusammensetzungen sowie Behandlungsverfahren unter deren Verwendung
US6919370B2 (en) * 2000-11-28 2005-07-19 Transform Pharmaceuticals, Inc. Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
JP2008543789A (ja) * 2005-06-17 2008-12-04 ホスピラ オーストラリア ピーティーワイ エルティーディー ドセタキセルの液体薬学的処方物
GB0517092D0 (en) * 2005-08-19 2005-09-28 Novartis Ag New compositions containing taxane derivatives
BRPI0600194A (pt) * 2006-01-30 2007-10-23 Quiral Quimica Do Brasil S A composições farmacêuticas contendo docetaxel e um inibidor de degradação e processo de obtenção das mesmas
CN101023940A (zh) * 2006-02-20 2007-08-29 郝守祝 一种紫杉烷类化合物的药用组合物、制备方法及用途
CN100595270C (zh) * 2006-04-12 2010-03-24 中国科学院大连化学物理研究所 紫杉烷木糖苷去糖微生物及其应用
AU2007246077A1 (en) * 2006-05-03 2007-11-08 I.Q.A., A.S. Pharmaceutical composition containing taxane derivative destined for the preparation of an infusion solution, method of preparation thereof and use thereof
WO2007134354A1 (de) * 2006-05-23 2007-11-29 Ebewe Pharma Ges.M.B.H. Nfg. Kg Pharmazeutische formulierung
EP1946747A1 (de) * 2007-01-17 2008-07-23 Sandoz AG Taxanderivat enthaltende pharmazeutische Zusammensetzung von verbesserter Stabilität
CZ200756A3 (cs) * 2007-01-23 2008-07-30 Heaton, A. S. Dvousložková farmaceutická kompozice obsahující taxan
CN101396354B (zh) * 2007-09-30 2010-12-01 江苏恒瑞医药股份有限公司 一种稳定的塔三烷类化合物液体组合物及其制备方法和其应用
EP2077132A1 (de) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung
KR101053780B1 (ko) * 2008-02-29 2011-08-02 동아제약주식회사 도세탁셀을 함유하는 단일액상의 안정한 약제학적 조성물
ES2344674B1 (es) * 2008-08-07 2011-06-29 Gp Pharm, S.A. Composicion farmaceutica inyectable de taxanos.
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
JP5763053B2 (ja) 2009-05-18 2015-08-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アダプタ、吸入器具及びアトマイザ
BR112012012475B1 (pt) 2009-11-25 2020-03-03 Boehringer Ingelheim International Gmbh Nebulizador
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011160932A1 (en) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nebulizer
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
EP2829273B1 (de) * 2012-03-22 2018-08-29 Ensuiko Sugar Refining Co., Ltd. Verfahren zur herstellung von liposomen zur verkapselung von paclitaxel-monoglycosid und/oder docetaxel-monoglycosid
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
JO3685B1 (ar) * 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
CN116036425A (zh) 2014-05-07 2023-05-02 勃林格殷格翰国际有限公司 喷雾器、指示器装置及容器
WO2015169430A1 (en) 2014-05-07 2015-11-12 Boehringer Ingelheim International Gmbh Nebulizer
IL247927B (en) 2014-05-07 2022-09-01 Boehringer Ingelheim Int Container, a device that turns a liquid into a fine spray and use
TWI838700B (zh) * 2015-09-30 2024-04-11 香港商慧源香港創新有限公司 口服紫杉烷組合物及方法
JP7227159B2 (ja) 2017-01-16 2023-02-21 ナンシャ・バイオロジックス・（ホンコン）・リミテッド 酵母における組換えｉｌ－１１の生産のためのシステムおよび方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253738A1 (de) * 1986-07-17 1988-01-20 Rhone-Poulenc Sante Taxal-Derivate, deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
EP0522937A1 (de) * 1991-07-08 1993-01-13 Aventis Pharma S.A. Taxanderivate enthaltende Arzneimittel
WO1994012030A1 (en) * 1992-11-27 1994-06-09 Napro Biotherapeutics, Inc. Injectable composition
WO1994012171A1 (fr) * 1992-12-02 1994-06-09 Rhone-Poulenc Rorer S.A. Compositions injectables a base de derives des taxanes
WO1994012198A1 (en) * 1992-11-27 1994-06-09 F.H. Faulding & Co. Limited Injectable taxol composition
EP0645145A2 (de) * 1993-09-29 1995-03-29 Bristol-Myers Squibb Company Stabilisierte Arzneimittel und stabilisierendes Lösungsmittel
WO1996029070A1 (en) * 1995-03-17 1996-09-26 The Board Of Regents, The University Of Texas System Extended stability formulations for paclitaxel

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253738A1 (de) * 1986-07-17 1988-01-20 Rhone-Poulenc Sante Taxal-Derivate, deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
EP0522937A1 (de) * 1991-07-08 1993-01-13 Aventis Pharma S.A. Taxanderivate enthaltende Arzneimittel
EP0522936A1 (de) * 1991-07-08 1993-01-13 Aventis Pharma S.A. Taxanderivate enthaltende Arzneimittel
WO1994012030A1 (en) * 1992-11-27 1994-06-09 Napro Biotherapeutics, Inc. Injectable composition
WO1994012198A1 (en) * 1992-11-27 1994-06-09 F.H. Faulding & Co. Limited Injectable taxol composition
WO1994012171A1 (fr) * 1992-12-02 1994-06-09 Rhone-Poulenc Rorer S.A. Compositions injectables a base de derives des taxanes
EP0645145A2 (de) * 1993-09-29 1995-03-29 Bristol-Myers Squibb Company Stabilisierte Arzneimittel und stabilisierendes Lösungsmittel
WO1996029070A1 (en) * 1995-03-17 1996-09-26 The Board Of Regents, The University Of Texas System Extended stability formulations for paclitaxel

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
B.D.TARR ET AL.: "A NEW PARENTERAL VEHICLE FOR THE ADMINISTRATION OF SOME POORLY SOLUBLE ANTI-CANCER DRUGS", J. PARENTER. SCI. TECHNOL., vol. 41, no. 1, 1987, pages 31 - 33 *
CHEMICAL ABSTRACTS, vol. 106, no. 22, 1 June 1987, Columbus, Ohio, US; abstract no. 182581c, XP002054344 *
See also references of WO9723208A1 *

Also Published As

Publication number Publication date
WO1997023208A1 (en) 1997-07-03
AU724842B2 (en) 2000-09-28
EP0876145A1 (de) 1998-11-11
CA2240595A1 (en) 1997-07-03
KR970032859A (ko) 1997-07-22
AU1294997A (en) 1997-07-17
CN1209059A (zh) 1999-02-24

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