EP0876145A4 - Composition de taxane et procede s'y rapportant - Google Patents

Composition de taxane et procede s'y rapportant

Info

Publication number
EP0876145A4
EP0876145A4 EP96943805A EP96943805A EP0876145A4 EP 0876145 A4 EP0876145 A4 EP 0876145A4 EP 96943805 A EP96943805 A EP 96943805A EP 96943805 A EP96943805 A EP 96943805A EP 0876145 A4 EP0876145 A4 EP 0876145A4
Authority
EP
European Patent Office
Prior art keywords
taxane composition
taxane
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP96943805A
Other languages
German (de)
English (en)
Other versions
EP0876145A1 (fr
Inventor
Bijan Almassian
William Choy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genelabs Technologies Inc
Original Assignee
Genelabs Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genelabs Technologies Inc filed Critical Genelabs Technologies Inc
Publication of EP0876145A1 publication Critical patent/EP0876145A1/fr
Publication of EP0876145A4 publication Critical patent/EP0876145A4/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
EP96943805A 1995-12-21 1996-12-19 Composition de taxane et procede s'y rapportant Ceased EP0876145A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57620495A 1995-12-21 1995-12-21
US576204 1995-12-21
PCT/US1996/020187 WO1997023208A1 (fr) 1995-12-21 1996-12-19 Composition de taxane et procede s'y rapportant

Publications (2)

Publication Number Publication Date
EP0876145A1 EP0876145A1 (fr) 1998-11-11
EP0876145A4 true EP0876145A4 (fr) 1999-04-21

Family

ID=24303400

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96943805A Ceased EP0876145A4 (fr) 1995-12-21 1996-12-19 Composition de taxane et procede s'y rapportant

Country Status (6)

Country Link
EP (1) EP0876145A4 (fr)
KR (1) KR970032859A (fr)
CN (1) CN1209059A (fr)
AU (1) AU724842B2 (fr)
CA (1) CA2240595A1 (fr)
WO (1) WO1997023208A1 (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6964946B1 (en) * 1995-10-26 2005-11-15 Baker Norton Pharmaceuticals, Inc. Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same
US5922754A (en) * 1998-10-02 1999-07-13 Abbott Laboratories Pharmaceutical compositions containing paclitaxel
EP1479382A1 (fr) * 1999-06-18 2004-11-24 IVAX Research, Inc. Compositions pharmaceutiques orales contenant des taxanes et méthodes de traitement dans lesquelles lesdites compositions sont utilisées
JP2004536026A (ja) * 2000-11-28 2004-12-02 トランスフォーム ファーマシューティカルズ，インコーポレーティッド． パクリタキセル、その誘導体、および薬剤として許容される塩を含む医薬品製剤
EP1904052A4 (fr) * 2005-06-17 2008-12-10 Hospira Australia Pty Ltd Compositions pharmaceutiques liquides de docétaxel
GB0517092D0 (en) * 2005-08-19 2005-09-28 Novartis Ag New compositions containing taxane derivatives
BRPI0600194A (pt) * 2006-01-30 2007-10-23 Quiral Quimica Do Brasil S A composições farmacêuticas contendo docetaxel e um inibidor de degradação e processo de obtenção das mesmas
CN101023940A (zh) * 2006-02-20 2007-08-29 郝守祝 一种紫杉烷类化合物的药用组合物、制备方法及用途
CN100595270C (zh) * 2006-04-12 2010-03-24 中国科学院大连化学物理研究所 紫杉烷木糖苷去糖微生物及其应用
WO2007124700A2 (fr) * 2006-05-03 2007-11-08 I.Q.A., A.S. Composition pharmaceutique contenant un dérivé de taxane, destinée à l'élaboration d'une solution pour perfusion, sa méthode d'élaboration et ses applications
WO2007134354A1 (fr) * 2006-05-23 2007-11-29 Ebewe Pharma Ges.M.B.H. Nfg. Kg Formulation pharmaceutique
EP1946747A1 (fr) * 2007-01-17 2008-07-23 Sandoz AG Composition pharmaceutique à stabilité améliorée contenant des dérivés de taxane
CZ200756A3 (cs) * 2007-01-23 2008-07-30 Heaton, A. S. Dvousložková farmaceutická kompozice obsahující taxan
CN101396354B (zh) * 2007-09-30 2010-12-01 江苏恒瑞医药股份有限公司 一种稳定的塔三烷类化合物液体组合物及其制备方法和其应用
EP2077132A1 (fr) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur, dispositif de stockage et procédé pour la distribution d'une formulation
KR101053780B1 (ko) * 2008-02-29 2011-08-02 동아제약주식회사 도세탁셀을 함유하는 단일액상의 안정한 약제학적 조성물
ES2344674B1 (es) 2008-08-07 2011-06-29 Gp Pharm, S.A. Composicion farmaceutica inyectable de taxanos.
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
WO2010133294A2 (fr) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapteur, dispositif d'inhalation et nébuliseur
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EA026241B1 (ru) 2009-11-25 2017-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Распылитель
WO2011160932A1 (fr) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nébuliseur
WO2012130757A1 (fr) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Appareil médical pourvu d'un récipient
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013141346A1 (fr) * 2012-03-22 2013-09-26 塩水港精糖株式会社 Procédé de fabrication d'un liposome encapsulant un mono-glycoside du paclitaxel et/ou mono-glycoside de docétaxel
WO2013152894A1 (fr) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Pulvérisateur comprenant des moyens de détrompage
JO3685B1 (ar) * 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
PL2835146T3 (pl) 2013-08-09 2021-04-06 Boehringer Ingelheim International Gmbh Nebulizator
EP3030298B1 (fr) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nébuliseur
HUE055604T2 (hu) 2014-05-07 2021-12-28 Boehringer Ingelheim Int Porlasztó
AU2015257878B2 (en) 2014-05-07 2019-08-08 Boehringer Ingelheim International Gmbh Container, nebulizer and use
EA035261B1 (ru) 2014-05-07 2020-05-21 Бёрингер Ингельхайм Интернациональ Гмбх Небулайзер и контейнер
TWI838700B (zh) * 2015-09-30 2024-04-11 香港商慧源香港創新有限公司 口服紫杉烷組合物及方法
EP3568410A4 (fr) 2017-01-16 2020-12-23 Nansha Biologics (Hong Kong) Limited Systèmes et procédés de production d'il-11 recombinant dans une levure

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253738A1 (fr) * 1986-07-17 1988-01-20 Rhone-Poulenc Sante Dérivés du taxol, leur préparation et les compositions pharmaceutiques qui les contiennent
EP0522936A1 (fr) * 1991-07-08 1993-01-13 Aventis Pharma S.A. Nouvelles compositions à base de dérivés de la classe des taxanes
WO1994012171A1 (fr) * 1992-12-02 1994-06-09 Rhone-Poulenc Rorer S.A. Compositions injectables a base de derives des taxanes
WO1994012198A1 (fr) * 1992-11-27 1994-06-09 F.H. Faulding & Co. Limited Composition a base de taxol injectable
WO1994012030A1 (fr) * 1992-11-27 1994-06-09 Napro Biotherapeutics, Inc. Composition injectable
EP0645145A2 (fr) * 1993-09-29 1995-03-29 Bristol-Myers Squibb Company Composition pharmaceutique stabilisée et solvant stabilisant
WO1996029070A1 (fr) * 1995-03-17 1996-09-26 The Board Of Regents, The University Of Texas System Preparations de paclitaxel a stabilite amelioree

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253738A1 (fr) * 1986-07-17 1988-01-20 Rhone-Poulenc Sante Dérivés du taxol, leur préparation et les compositions pharmaceutiques qui les contiennent
EP0522936A1 (fr) * 1991-07-08 1993-01-13 Aventis Pharma S.A. Nouvelles compositions à base de dérivés de la classe des taxanes
EP0522937A1 (fr) * 1991-07-08 1993-01-13 Aventis Pharma S.A. Compositions à base de dérivés de la classe des taxanes
WO1994012198A1 (fr) * 1992-11-27 1994-06-09 F.H. Faulding & Co. Limited Composition a base de taxol injectable
WO1994012030A1 (fr) * 1992-11-27 1994-06-09 Napro Biotherapeutics, Inc. Composition injectable
WO1994012171A1 (fr) * 1992-12-02 1994-06-09 Rhone-Poulenc Rorer S.A. Compositions injectables a base de derives des taxanes
EP0645145A2 (fr) * 1993-09-29 1995-03-29 Bristol-Myers Squibb Company Composition pharmaceutique stabilisée et solvant stabilisant
WO1996029070A1 (fr) * 1995-03-17 1996-09-26 The Board Of Regents, The University Of Texas System Preparations de paclitaxel a stabilite amelioree

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
B.D.TARR ET AL.: "A NEW PARENTERAL VEHICLE FOR THE ADMINISTRATION OF SOME POORLY SOLUBLE ANTI-CANCER DRUGS", J. PARENTER. SCI. TECHNOL., vol. 41, no. 1, 1987, pages 31 - 33 *
CHEMICAL ABSTRACTS, vol. 106, no. 22, 1 June 1987, Columbus, Ohio, US; abstract no. 182581c, XP002054344 *
See also references of WO9723208A1 *

Also Published As

Publication number Publication date
EP0876145A1 (fr) 1998-11-11
AU1294997A (en) 1997-07-17
KR970032859A (ko) 1997-07-22
CN1209059A (zh) 1999-02-24
WO1997023208A1 (fr) 1997-07-03
CA2240595A1 (fr) 1997-07-03
AU724842B2 (en) 2000-09-28

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