Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
  • A61J1/14—Details; Accessories therefor
  • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
  • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
  • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
  • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
  • B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces
  • B65D81/3211—Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
  • A61J1/14—Details; Accessories therefor
  • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
  • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
  • A61J1/202—Separating means
  • A61J1/2041—Separating means having removable plugs

Definitions

• the present invention relates to a device for dispensing a fluid product, and more particularly a device for dispensing a liquid medicament contained in a hermetically closed container.
• a device for dispensing a fluid product and more particularly a device for dispensing a liquid medicament contained in a hermetically closed container.
• the liquid between the moment when it is placed in the reservoir of the device, and the moment when it is dispensed, that is to say during the storage period, tends to evaporate, or may be contaminated with external agents such as bacteria, or be oxidized by oxygen. In the case of certain drugs, this can lead to a total loss of its effectiveness.
• a first type of device comprises a reservoir, the opening of which is closed by a membrane, said membrane being pierced or torn by a suitable device at the time of actuation of the device.
• a suitable device at the time of actuation of the device.
• Such systems are described in particular in documents EP-0 407 276 and US-4 017 007.
• the disadvantage of these membrane devices lies in the fact that the membrane must be applied to the opening of the container with care, which requires a relatively assembly step complex after the tank has been filled. Thus, the liquid product contained in the reservoir is exposed to possible contamination for the time required to apply said membrane.
• a rubber element, used as a pump piston is pierced at the time of actuation of the dispenser by a needle which is connected to the spray outlet of the dispenser.
• the dimension of the piston must be such that it can slide relatively easily in the reservoir.
• the interference between the piston and the reservoir i.e. the pressure exerted by the piston against the walls of the reservoir, and therefore the contact surface between these two elements, must also be as low as possible to avoid friction problems when actuating the dispenser, as well as to minimize the force required to actuate the dispenser.
• This characteristic of low interference results in limited protection against evaporation under certain conditions, such as for example with high storage temperatures, and can also allow contamination of the product, for example by penetration of oxygen.
• the object of the present invention is to provide a device for dispensing a fluid product which does not have the abovementioned drawbacks.
• the present invention aims to provide a fluid dispensing device which simultaneously ensures an effective and hermetic closure of the product reservoir and which comprises a piston which can easily slide in said reservoir to ensure safe, reliable and easy actuation. from the distributor.
• the present invention therefore relates to a device for dispensing a fluid product contained in a reservoir provided with an opening, said device comprising a movable element between a rest position, where it closes the opening of said reservoir, and a position actuator, means for connecting the interior of the reservoir to a product expulsion channel, and an actuator for moving said element towards its actuation position, said element sliding in leaktight manner in said reservoir so that the product is expelled through said expulsion channel, characterized in that said element comprises sealing means which, in the element's rest position, cooperate with it to increase the interference between the element and the reservoir thus guaranteeing a completely hermetic closure of the reservoir, said actuating member comprising means for moving said sealing means and ai nsi decrease the interference between the element and the reservoir, so that the element
• the element acts, in its rest position, as a cap which hermetically seals the reservoir, and, when it moves towards its actuation position, acts as a piston to expel the product contained in the reservoir .
• the actuating member comprises means for securing the element and the actuating member after displacement of the sealing means by said means for displacing.
• said element is substantially cylindrical and has a substantially cylindrical passage connecting the interior of the reservoir, substantially cylindrical, to said expulsion channel, said sealing means comprising a closure member which seals said passage sealingly in the rest position of the element, said means for moving said closure member being adapted to open said passage.
• said closure member has a diameter greater than that of the passage so that, in the stopper position, it compresses the external lateral surface of the element against the internal walls of the reservoir, thus increasing the interference between the element and the tank in said rest position.
• said closure member is a ball which is force-fitted into the passage of the element after filling the reservoir.
• said actuating member comprises a rod traversed by the expulsion channel, said rod being able to slide in leaktight manner in the passage to move said obturation member.
• the end of said rod moves said closure member out of the passage in the tank, which has a recess for receiving said closure member.
• said element further comprises blocking means which prevent movement of the element when it is in its rest position, said actuating member further comprising means for moving said blocking means.
• said blocking means comprise an annular flange which, in the element's rest position, cooperates with the opening of the reservoir to prevent movement of the element in the reservoir.
• the actuating member comprises, in extension of the rod, a shoulder whose outside diameter is less than the inside diameter of the reservoir, and, in extension of said shoulder, a groove, so that upon actuation of the actuating member, the rod slides in the passage of the element to move the shutter member first, then the shoulder cooperates with the outer radial surface of the element by exerting a force which urges said element towards its actuating position, said force being greater than the elasticity of the annular flange, so that the latter folds around said shoulder, in said groove, to allow the movement of the element in said tank.
• the length formed by the addition of the radius of the shoulder and the thickness of the annular flange is approximately equal to the interior radius of the tank, so that the element can slide with sealing and with low friction in The reservoir.
• said element is made of an elastomeric material.
• FIG. 1 represents a schematic view in partial section of the dispensing device according to an advantageous embodiment of the invention, before
• Figure 2 shows a view similar to that of Figure 1, during 1 actuation of the device.
• the device comprises a reservoir 1, preferably substantially cylindrical, comprising an opening.
• An element 2, preferably substantially cylindrical, is disposed in said reservoir 1 and is movable between a rest position, shown in FIG. 1, where it closes the opening of said reservoir 1, and an actuating position shown in FIG. 2.
• This element 2 in its rest position, closes the reservoir in a completely hermetic manner and consequently prevents any contamination or any evaporation of the product contained in the reservoir 1. In this position, the element 2 therefore acts as a plug.
• the device further comprises an actuating member adapted to move said element 2 towards its actuating position, said element 2 sliding in leaktight manner in said reservoir 1 during this displacement and therefore acting in this situation as a piston of the dispenser.
• the dispensing device further comprises means for connecting the interior of the reservoir to a product expulsion channel 10 which is connected to the outlet of the dispenser (not shown).
• the dispensing device object of the present invention, adapts to any type of product dispenser in which a product contained in a hermetically sealed reservoir must be dispensed, for example sprayed.
• the element 2 is in its rest position in which it acts as a plug. It is made of a suitable elastomeric material, for example rubber, and has a passage 3 which passes through it axially, preferably at its center.
• the passage 3 is preferably substantially cylindrical.
• a closure member 5 is disposed in the passage 3 to close the reservoir of waterproof and totally airtight.
• this shutter member 5 is spherical and can be produced for example in the form of a ball made of a suitable material such as stainless steel.
• the device further comprises an actuating member 6 which comprises a rod 7 extending axially.
• the actuating member 6 comprises an extension of said rod 7 a shoulder 8, and an extension of said shoulder 8, a recess 9, for example a groove.
• This actuating member is traversed by a product expulsion channel 10, preferably axial, which is connected on the one hand to the dispensing outlet of the distributor and which opens on the other hand to the end of said rod 7
• said rod 7 has a diameter very slightly greater than the inside diameter of passage 3 of element 2.
• the actuating member 6 is connected to an actuating device such as a pusher (not shown) of the dispenser.
• the element 2 further comprises locking means 4, preferably made in the form of an annular flange 4 which, in its position of rest of the element 2, cooperates with the reservoir 1 to prevent the displacement of the item 2 in the tank.
• said annular flange 4 is made in one piece with the element 2 and is supported in the rest position of the element 2, on the upper end of the walls of the tank 1.
• the operation of the device is as follows.
• the actuating member 6 When the device is actuated, the actuating member 6 is moved relative to the reservoir 1, so that the end of the rod 7 pushes the ball 5 out of the passage 3 of the element 2.
• the ball 5 when the ball 5 is expelled from the passage 3, it no longer exerts a compressive force on the side walls of the element 2 against the walls of the tank 1 and the interference between these two elements is greatly reduced.
• the outside diameter of the rod 7 is such that the said rod 7 slides in leaktight manner in the said passage 3 and the length of the said rod 7 is such that the shoulder 8, arranged as an extension of the rod 7, comes to rest on the external radial surface of element 2 until after expulsion of said ball 5 from passage 3.
• the diameter of the shoulder 8 is necessarily less than the inside diameter of the reservoir 1, to allow actuation of the dispensing device.
• the dimension of said shoulder 8 is such that the length formed by the addition of the radius of the shoulder 8 and the thickness of the annular flange 4 is approximately equal to the interior radius of the tank 1, so that after that the annular flange 4 is folded around the shoulder 8, the outside diameter of the assembly, at the level of said shoulder 8, is approximately equal to the inside diameter of the reservoir 1.
• the interference between the element 2 and the tank 1 is practically not increased by the presence of the annular flange 4.
• the final folded position of the annular flange 5 therefore allows its penetration into the reservoir without causing significant friction and guarantees perfect efficiency between the element 2 and the actuating member 6.
• the element 2 adopts its piston function and can slide in leaktight manner in the reservoir 1 with very low friction, which makes it possible to ensure safe, reliable and easy actuation of the dispensing device.
• the reservoir 1 may include in its bottom a recess 1a intended to receive the closure member 5 after the latter has been expelled from the passage 3 by the rod 7 of the member actuation 6.
• this recess is advantageously of substantially spherical shape.
• the invention therefore makes it possible to guarantee the tightness of the product from its installation in the tank and until its distribution, throughout the duration of the storage, whatever the conditions, and during the entire distribution process. .

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• Health & Medical Sciences (AREA)
• Engineering & Computer Science (AREA)
• Mechanical Engineering (AREA)
• Pharmacology & Pharmacy (AREA)
• Life Sciences & Earth Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• General Health & Medical Sciences (AREA)
• Public Health (AREA)
• Veterinary Medicine (AREA)
• Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
• Closures For Containers (AREA)
• Medical Preparation Storing Or Oral Administration Devices (AREA)

Applications Claiming Priority (3)

Publications (2)

Family

ID=9488985

Family Applications (1)

Country Status (6)

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Family Cites Families (6)

• 1996
  • 1996-02-08 FR FR9601553A patent/FR2744702B1/fr not_active Expired - Fee Related
• 1997
  • 1997-01-31 JP JP52811197A patent/JP2000505400A/ja active Pending
  • 1997-01-31 US US09/117,684 patent/US6164501A/en not_active Expired - Lifetime
  • 1997-01-31 EP EP97902272A patent/EP0879191B1/de not_active Expired - Lifetime
  • 1997-01-31 WO PCT/EP1997/000416 patent/WO1997029028A1/fr not_active Ceased
  • 1997-01-31 DE DE69700432T patent/DE69700432T2/de not_active Expired - Lifetime

Non-Patent Citations (1)

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