EP0879191B1 - Vorrichtung zum dosieren eines fliessfähigen mediums in einem hermetisch geschlossenen behälter - Google Patents

Vorrichtung zum dosieren eines fliessfähigen mediums in einem hermetisch geschlossenen behälter Download PDF

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Publication number
EP0879191B1
EP0879191B1 EP97902272A EP97902272A EP0879191B1 EP 0879191 B1 EP0879191 B1 EP 0879191B1 EP 97902272 A EP97902272 A EP 97902272A EP 97902272 A EP97902272 A EP 97902272A EP 0879191 B1 EP0879191 B1 EP 0879191B1
Authority
EP
European Patent Office
Prior art keywords
container
passage
closure member
tank
shoulder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP97902272A
Other languages
English (en)
French (fr)
Other versions
EP0879191A1 (de
Inventor
Giuseppe Stradella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RG SAS Di Rosaria Galli and Co
Tebro SA
Original Assignee
RG SAS Di Rosaria Galli and Co
Tebro SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RG SAS Di Rosaria Galli and Co, Tebro SA filed Critical RG SAS Di Rosaria Galli and Co
Publication of EP0879191A1 publication Critical patent/EP0879191A1/de
Application granted granted Critical
Publication of EP0879191B1 publication Critical patent/EP0879191B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces
    • B65D81/3211—Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2041—Separating means having removable plugs

Definitions

  • the present invention relates to a device for distribution of fluid, and more particularly a device for dispensing a liquid medicine contained in a hermetically sealed container.
  • the liquid between the moment when it is put in place in the device tank, and when it is distributed, i.e. during the period of storage, tends to evaporate, or can be contaminated by external agents such as bacteria, or be oxidized by oxygen. In the case of some medication, this can cause total loss of sound efficiency.
  • a first type of device comprises a reservoir whose opening is closed by a membrane, said membrane being pierced or torn by a device appropriate at the time of actuation of the device.
  • a second type of system an element in rubber, used as pump piston is pierced when the dispenser is activated by a needle which is connected to the spray outlet of the distributor.
  • a needle which is connected to the spray outlet of the distributor.
  • the piston size should be such that it can slide relatively easily in The reservoir.
  • the interference between the piston and tank i.e. the pressure exerted by the piston against the walls of the tank, and by therefore the contact surface between these two elements, should be as low as possible to avoid friction problems when actuating the distributor, as well as to minimize the force required at the actuation of the distributor.
  • This characteristic of low interference results in limited protection against evaporation under certain conditions, such as by example with high storage temperatures, and can also authorize product contamination, for example example by oxygen penetration.
  • the object of the present invention is to provide a device for dispensing a fluid which does not not reproduce the aforementioned drawbacks.
  • the object of the present invention is to provide a fluid dispensing device which ensures simultaneously an efficient and hermetic closure of the product tank and which has a piston which can easily slide into said tank to ensure safe, reliable and easy actuation of the dispenser.
  • the present invention therefore relates to a device for dispensing a fluid product contained in a tank provided with an opening, said device comprising a movable element between a rest position, where it closes the opening of said tank, and a position actuation means for connecting the interior of the reservoir to a product expulsion channel, and an organ actuation to move said element towards its actuation position, said sliding element of tightly in said tank so that the product is expelled through said expulsion channel, characterized in that said element comprises means which, in the element's rest position, cooperate with it to increase interference between the element and the tank thus guaranteeing a totally hermetic closure of the reservoir, said member actuator comprising means for moving said sealing means and thus reduce the interference between the element and the tank, so that the element moves in the tank to its actuation position with low friction.
  • the element acts, in its rest position, in as long as the cap hermetically seals the tank, and when it moves to its operating position, acts as a piston to expel the contained product in the tank.
  • the actuating member includes means for securing the element and the organ actuation after displacement of the sealing means by said means for moving.
  • said element is substantially cylindrical and has a passage substantially cylindrical connecting the inside of the tank, substantially cylindrical, at said expulsion channel, said means sealing comprising a shutter member which seals said passage sealingly in the rest position of the element, said means for moving said member shutter being adapted to open said passage.
  • said closure member has a diameter higher than that of the passage so that in the stopper position, it compresses the surface lateral exterior of the element against the walls inside the tank, increasing interference between the element and the tank in said position of rest.
  • said shutter member is a ball which is force fitted into the passage of the element after filling the tank.
  • said actuating member comprises a rod through which the expulsion channel passes, said rod able to slide tightly in the passage for moving said shutter member.
  • the end of said rod moves said shutter member out of the passage in the tank, which has a recess for receiving said obturation organ.
  • said element further comprises blocking means which prevent movement of the element when in its rest position, said element actuator further comprising means for moving said blocking means.
  • said blocking means comprise an annular flange which, in the rest position of the element, cooperates with the opening of the reservoir for prevent movement of the element in the tank.
  • the actuator comprises, in extension of the rod, a shoulder whose diameter outside is less than the inside diameter of the tank, and, in extension of said shoulder, a groove, so that upon actuation of the organ actuation, the rod slides in the passage of the element for first moving the shutter member, then the shoulder cooperates with the radial surface outside of the element by exerting a force which urges said element towards its actuation position, said force being greater than the elasticity of the flange annular, so that it folds around said shoulder, in said groove, to allow the displacement of the element in said tank.
  • the length formed by the addition of the radius of shoulder and thickness of flange annular is approximately equal to the interior radius of the tank, so that the element can slide with tightness and with low friction in the tank.
  • said element is produced in a elastomeric material.
  • the device comprises a reservoir 1, preferably substantially cylindrical, having an opening.
  • a element 2 preferably substantially cylindrical is disposed in said tank 1 and is movable between a rest position, shown in Figure 1, where it closes the opening of said reservoir 1, and a position actuation shown in FIG. 2.
  • This element 2 in its rest position, seals the tank so completely sealed and therefore prevents any contamination or any evaporation of the product contained in the tank 1. In this position, the element 2 therefore acts as a cap.
  • the device further comprises a actuator adapted to move said element 2 towards its actuation position, said element 2 sliding tightly in said tank 1 during this displacement and therefore acting in this situation as a distributor piston.
  • the distribution device further comprises means to connect the inside of the tank to a channel expelling product 10 which is connected to the outlet of the distributor (not shown).
  • the distribution device object of the present invention, adapts to any type of product distributor in which a product contained in a tightly closed tank must be distributed, for example sprayed.
  • element 2 is in its rest position in which it acts as plug. It is made of an elastomeric material suitable, for example rubber, and has a passage 3 which crosses it axially, preferably in its center. Passage 3 is preferably substantially cylindrical.
  • a closure member 5 is arranged in passage 3 to close the reservoir of waterproof and totally airtight.
  • this closure member 5 is spherical and can be produced for example in the form of a ball of material suitable such as stainless steel.
  • This ball 5 has a diameter greater than the inside diameter of the passage 3 so that when disposed in said passage 3, it closes on the one hand this passage and on the other apart it exerts high compressive forces on the rubber side walls of element 2, against the tank 1.
  • high interference is created between element 2 and the walls of tank 1 which guarantees an efficient, waterproof and totally closed hermetic of the tank in the rest position, before actuation.
  • the device further comprises a member actuator 6 which has a rod 7 extending axially.
  • the actuating member 6 comprises an extension of said rod 7 a shoulder 8, and in extension of said shoulder 8, a recess 9, by example a groove.
  • This actuator is crossed by a product expulsion channel 10, from axial preference, which is connected on the one hand to the outlet of distribution of the distributor and which leads on the other hand at the end of said rod 7.
  • said rod 7 has a diameter very slightly greater than the diameter inside passage 3 of element 2.
  • the actuator 6 is connected to a device such as a push button (not shown) on the distributor.
  • the element 2 also comprises locking means 4, preferably made in the form of an annular flange 4 which, in its rest position of the element 2, cooperates with tank 1 to prevent displacement of item 2 in the tank.
  • said annular flange 4 is made in one piece with the element 2 and is supported in the rest position of the element 2, on the upper end of the tank walls 1.
  • the operation of the device is as follows.
  • the organ actuator 6 When the device is actuated, the organ actuator 6 is moved relative to reservoir 1, so that the end of the rod 7 pushes the ball 5 out of passage 3 of element 2.
  • the organ actuator 6 When ball 5 is expelled from passage 3, it no longer exerts compression force on the side walls of element 2 against the walls of tank 1 and the interference between these two elements is strongly diminished.
  • the outside diameter of the rod 7 is such that said rod 7 slides tightly in said passage 3 and the length of said rod 7 is such that the shoulder 8, arranged as an extension of the rod 7, comes to rest on the external radial surface of element 2 until after expulsion of said ball 5 from passage 3.
  • the diameter of the shoulder 8 is necessarily smaller than the inside diameter of tank 1, for allow actuation of the dispensing device.
  • the dimension of said shoulder 8 is such that the length formed by the addition of the radius of the shoulder 8 and the thickness of the annular flange 4 is approximately equal to the interior radius of the tank 1, so that after that the annular flange 4 has folded around the shoulder 8, the outside diameter of the assembly, at level of said shoulder 8, approximately equal to the diameter inside the tank 1. So the interference between element 2 and tank 1 is practically not increased by the presence of the annular flange 4.
  • element 2 adopts its piston function and can slide tightly in the tank 1 with very low friction, which ensures a safe, reliable and easy actuation of the distribution.
  • the tank 1 may include in its bottom a recess intended for receive the shutter member 5 after it has been expelled out of passage 3 by rod 7 of the organ actuation 6.
  • this recess is advantageously shaped substantially spherical.
  • the invention therefore makes it possible to guarantee the tightness of the product as soon as it is placed in the tank and up to its distribution, throughout the storage period whatever the conditions, and throughout distribution process.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Claims (12)

  1. Vorrichtung zur Abgabe eines fluidförmigen Produktes, die einen mit einer Öffnung versehenen Behälter (1) umfaßt, in welchem das Produkt enthalten ist, wobei die Vorrichtung weiterhin ein Element (2) aufweist, das zwischen einer Ruhelage, in der es die Öffnung des Behälters (1) verschließt, und einer Betätigungsstellung bewegbar ist, sowie Einrichtungen zum Verbinden des Inneren des Behälters (1) mit einem Ausstoßkanal (10) für das Produkt, und ein Betätigungsorgan (6) zum Verschieben des Elementes (2) zu seiner Betätigungsstellung hin, wobei das Element (2) in dichter Weise in dem Behälter (1) derart gleitet, daß das Produkt durch den Ausstoßkanal (10) hindurch abgegeben wird, dadurch gekennzeichnet, daß das Element (2) einen Durchgang (3) umfaßt, der das Innere des Behälters (1) mit dem Ausstoßkanal (10) verbindet, und daß Dichteinrichtungen ein Verschlußorgan (5) umfassen, das in der Ruhelage des Elementes (2) mit diesem zusammenwirkt, um besagten Durchgang (3) in dichter Weise zu verschließen und eine starke Wechselwirkung zwischen dem Element (2) und dem Behälter (1) zu erzeugen und somit einen völlig hermetischen Verschluß des Behälters (1) zu garantieren, wobei das Betätigungsorgan (6) Mittel (7) umfaßt, die dazu dienen, daß Verschlußorgan (5) zu verschieben, um den Durchgang (3) zu öffnen und die Wechselwirkung zwischen dem Element (2) und dem Behälter (1) derart zu vermindem, daß sich das Element (2) im Behälter (1) mit geringer Reibung zu seiner Betätigungsstellung hin verschiebt.
  2. Vorrichtung nach Anspruch 1, bei der das Betätigungsorgan Einrichtungen (8, 9) zum Verbinden des Elementes (2) und des Betätigungsorganes (6) nach dem Verschieben des Verschlußorgans (5) durch die zum Verschieben dienenden Einrichtungen (7) umfaßt.
  3. Vorrichtung nach Anspruch 1 oder 2, bei der der Behälter (1), das Element (2) unter Durchgang (3) im wesentlichen zylindrisch sind.
  4. Vorrichtung nach einem der vorhergehenden Ansprüche, bei der das Verschlußorgan (5) einen Durchmesser besitzt, der größer ist als der des Durchgangs (3) derart, daß es in der Ruhelage des Stopfens die seitliche Außenoberfläche des Elements (2) gegen die Innenwände des Behälters zusammendrückt und so die Wechselwirkung zwischen dem Element (2) und dem Behälter (1) in dieser Ruhelage verstärkt.
  5. Vorrichtung nach einem der vorhergehenden Ansprüche, bei der das Verschlußorgan (5) eine Kugel (5) ist, die mit Kraft in den Durchgang (3) des Elementes (2) nach dem Füllen des Behälters (1) eingedrückt ist.
  6. Vorrichtung nach einem der vorhergehenden Ansprüche, bei der das Betätigungsorgan (6) eine Stange (7) umfaßt, durch die hindurch sich der Ausstoßkanal (10) erstreckt, wobei die Stange (7) in dichter Weise in dem Durchgang (3) gleiten kann, um das Verschlußorgan (5) zu verschieben.
  7. Vorrichtung nach Anspruch 6, bei der das Ende der Stange (7) das Verschlußorgan (5) über den Durchgang (3) hinaus in den Behälter (1) verschiebt, der eine Ausnehmung (1a) umfaßt die zur Aufnahme des Verschlußorgans (5) dient.
  8. Vorrichtung nach Anspruch 6 oder 7, bei der das Element (2) weiterhin Blockiereinrichtungen (4) umfaßt, die eine Verschiebung des Elementes (2) verhindem, wenn es sich in seiner Ruhelage befindet, und wobei das Betätigungsorgan (6) weiterhin Einrichtungen (8, 9) umfaßt, die dazu dienen, die Blockiereinrichtungen (4) zu verschieben.
  9. Vorrichtung nach Anspruch 8, bei der die Blockiereinrichtungen (4) einen Ring (4) umfassen, der in der Ruhelage des Elementes (2) mit der Öffnung des Behälters (1) zusammenwirkt, um eine Verschiebung des Elementes in den Behälter zu verhindern.
  10. Vorrichtung nach Anspruch 9, bei der das Betätigungsorgan (6) in Verlängerung der Stange (7) eine Schulter (8) aufweist, deren Außendurchmesser kleiner ist als der Innendurchmesser des Behälters (1), und in Verlängerung dieser Schulter (8) eine Rille (9) derart, daß während der Betätigung des Betätigungsorgans (6) die Stange (7) im Durchgang (3) des Elementes (2) gleitet, um zunächst das Verschlußorgan (5) zu verschieben, worauf dann die Schulter (8) mit der radialen äußeren Oberfläche des Elementes (2) zusammenwirkt und eine Kraft ausübt, die dieses Element zu seiner Betätigungsstellung hin vorspannt, wobei diese Kraft größer ist als die Elastizität des Rings (4) derart, daß sich dieser um die Schulter (8) herum in die Rille (9) hinein umbiegt, um die Verschiebung des Elementes (2) in den Behälter (1) zu ermöglichen.
  11. Vorrichtung nach Anspruch 10, bei der die durch das Hinzufügen des Radius der Schulter (8) gebildete Länge und die Dicke des Rings (4) ungefähr gleich dem inneren Radius des Behälters (1) derart ist, daß das Element (2) dicht und mit geringer Reibung im Behälter (1) gleiten kann.
  12. Vorrichtung nach einem der vorhergehenden Ansprüche, bei der das Element (2) aus einem Elastomer hergestellt ist.
EP97902272A 1996-02-08 1997-01-31 Vorrichtung zum dosieren eines fliessfähigen mediums in einem hermetisch geschlossenen behälter Expired - Lifetime EP0879191B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9601553 1996-02-08
FR9601553A FR2744702B1 (fr) 1996-02-08 1996-02-08 Dispositif de distribution d'un produit fluide contenu dans un reservoir ferme hermetiquement
PCT/EP1997/000416 WO1997029028A1 (fr) 1996-02-08 1997-01-31 Dispositif de distribution d'un produit fluide contenu dans un reservoir ferme hermetiquement

Publications (2)

Publication Number Publication Date
EP0879191A1 EP0879191A1 (de) 1998-11-25
EP0879191B1 true EP0879191B1 (de) 1999-08-18

Family

ID=9488985

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97902272A Expired - Lifetime EP0879191B1 (de) 1996-02-08 1997-01-31 Vorrichtung zum dosieren eines fliessfähigen mediums in einem hermetisch geschlossenen behälter

Country Status (6)

Country Link
US (1) US6164501A (de)
EP (1) EP0879191B1 (de)
JP (1) JP2000505400A (de)
DE (1) DE69700432T2 (de)
FR (1) FR2744702B1 (de)
WO (1) WO1997029028A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2758799B1 (fr) * 1997-01-24 1999-04-02 Stago Diagnostica Bouchage pour flacon de reactif utilisable par un automate d'analyse
GB0228282D0 (en) * 2002-12-04 2003-01-08 Score Group Plc Fluid storage apparatus
FR2961087B1 (fr) 2010-06-09 2013-06-28 Allflex Europ Outil de prelevement d'un echantillon de tissu animal.
FR2963203B1 (fr) 2010-07-30 2013-11-15 Allflex Europ Ensemble de marquage et/ou de prelevement de tissu d'un animal et outil de marquage et/ou de prelevement correspondant.
FR2964649B1 (fr) 2010-09-15 2013-11-22 Herve Deflandre Dispositif d'alimentation en composants et installation comprenant un tel dispositif
FR2978328B1 (fr) * 2011-07-28 2014-10-24 Allflex Europ Systeme de prelevement d'au moins un echantillon de tissu animal, dispositif de prelevement, dispositif de stockage, et procede de fabrication correspondants.
US8801698B2 (en) * 2011-09-23 2014-08-12 Adapta Medica, Inc. Catheter reservoir seal
WO2016165125A1 (en) 2015-04-17 2016-10-20 Fontem Holdings 2 B.V. Liquid supply with spiral container
EP3358972B1 (de) 2015-10-08 2021-01-27 Fontem Holdings 1 B.V. Flüssigkeitsversorgung für eine elektronische rauchvorrichtung
FR3068624B1 (fr) 2017-07-06 2021-01-22 Aptar France Sas Dispositif de distribution de produit fluide.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2367883A (en) * 1942-09-21 1945-01-23 Frankfort Distilleries Inc Bottle closure
BE759374A (fr) * 1970-06-08 1971-04-30 Ims Ltd Emballage pour medicament
FR2188565A5 (de) * 1972-06-13 1974-01-18 Semco Emballage Conditio
EP0503867B1 (de) * 1991-03-08 1997-02-05 Material Engineering Technology Laboratory, Inc. Apparat zum Lagern und Mischen
JPH05212090A (ja) * 1992-02-04 1993-08-24 Material Eng Tech Lab Inc 輸液容器
JP3146465B2 (ja) * 1992-03-13 2001-03-19 株式会社ニッショー 薬液注入装置

Also Published As

Publication number Publication date
WO1997029028A1 (fr) 1997-08-14
EP0879191A1 (de) 1998-11-25
FR2744702B1 (fr) 1998-03-20
DE69700432T2 (de) 2000-05-04
DE69700432D1 (de) 1999-09-23
FR2744702A1 (fr) 1997-08-14
JP2000505400A (ja) 2000-05-09
US6164501A (en) 2000-12-26

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