EP0997143A3 - Weiche Kautablette - Google Patents

Weiche Kautablette Download PDF

Info

Publication number
EP0997143A3
EP0997143A3 EP99306455A EP99306455A EP0997143A3 EP 0997143 A3 EP0997143 A3 EP 0997143A3 EP 99306455 A EP99306455 A EP 99306455A EP 99306455 A EP99306455 A EP 99306455A EP 0997143 A3 EP0997143 A3 EP 0997143A3
Authority
EP
European Patent Office
Prior art keywords
chewable tablets
soft chewable
compressed
disintegratable
hardness
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP99306455A
Other languages
English (en)
French (fr)
Other versions
EP0997143A2 (de
EP0997143B1 (de
Inventor
Ronni L. Robinson
James R. Damon
James R. Mossop
Michael D. Palmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kenvue Brands LLC
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Publication of EP0997143A2 publication Critical patent/EP0997143A2/de
Publication of EP0997143A3 publication Critical patent/EP0997143A3/de
Application granted granted Critical
Publication of EP0997143B1 publication Critical patent/EP0997143B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP99306455A 1998-08-18 1999-08-17 Weiche Kautablette Expired - Lifetime EP0997143B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US135723 1987-12-21
US09/135,723 US6270790B1 (en) 1998-08-18 1998-08-18 Soft, convex shaped chewable tablets having reduced friability

Publications (3)

Publication Number Publication Date
EP0997143A2 EP0997143A2 (de) 2000-05-03
EP0997143A3 true EP0997143A3 (de) 2001-11-14
EP0997143B1 EP0997143B1 (de) 2007-12-19

Family

ID=22469364

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99306455A Expired - Lifetime EP0997143B1 (de) 1998-08-18 1999-08-17 Weiche Kautablette

Country Status (17)

Country Link
US (3) US6270790B1 (de)
EP (1) EP0997143B1 (de)
JP (1) JP2000095673A (de)
KR (1) KR20000017352A (de)
CN (1) CN1249176A (de)
AR (1) AR022065A1 (de)
AT (1) ATE381320T1 (de)
AU (1) AU773549B2 (de)
BR (1) BR9903736A (de)
CA (1) CA2280628C (de)
CO (1) CO5130019A1 (de)
DE (1) DE69937780T2 (de)
ES (1) ES2299234T3 (de)
NZ (1) NZ337310A (de)
PT (1) PT997143E (de)
SA (1) SA99200655B1 (de)
ZA (1) ZA995248B (de)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6270790B1 (en) * 1998-08-18 2001-08-07 Mxneil-Ppc, Inc. Soft, convex shaped chewable tablets having reduced friability
US20040081697A1 (en) * 1998-11-12 2004-04-29 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
US20040102486A1 (en) * 1998-11-12 2004-05-27 Smithkline Beecham Corporation Novel method of treatment
US20020122823A1 (en) * 2000-12-29 2002-09-05 Bunick Frank J. Soft tablet containing dextrose monohydrate
CA2447693A1 (en) * 2001-05-31 2002-12-05 Cima Labs Inc. Taste-masking of highly water-soluble drugs
IL159287A0 (en) * 2001-06-28 2004-06-01 Ucb Farchim Sa Tablet comprising cetirizine and pseudoephedrine
US20030060422A1 (en) 2001-08-31 2003-03-27 Balaji Venkataraman Tannate compositions and methods of treatment
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
CA2447984A1 (en) 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Dosage forms having an inner core and outer shell with different shapes
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
KR100446153B1 (ko) * 2001-10-24 2004-08-30 한국유나이티드제약 주식회사 가용화된 이부프로펜 함유 제제의 조성물 및 그의 제조방법
FR2831820B1 (fr) * 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation
FR2833173B1 (fr) * 2001-12-10 2004-08-27 Roquette Freres Preparation antipyretique renfermant du xylitol
EP1487419A2 (de) * 2002-03-20 2004-12-22 Elan Pharma International Limited Schnell auflösende dosierformen mit verringerter sprödigkeit
CA2481025A1 (en) 2002-04-04 2003-10-16 Tanya Havlir Palatable chewable tablet
EP1531680A1 (de) 2002-08-13 2005-05-25 Akzo Nobel Zusammensetzungen und verabreichungsprozess für einen zusatzstoff
AU2003299568B2 (en) 2002-11-27 2010-07-22 Ampio Pharmaceuticals, Inc. Treatment of diseases and conditions mediated by increased phosphorylation
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US20040265372A1 (en) * 2003-06-27 2004-12-30 David Wynn Soft tablet containing high molecular weight cellulosics
US20040265373A1 (en) * 2003-06-27 2004-12-30 David Wynn Soft tablet containing high molecular weight cellulosics
MXPA06002257A (es) * 2003-08-26 2006-05-17 Shire Holdings Ag Farmaceutica que comprende compuestos de lantano.
US7282217B1 (en) * 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
US20050192348A1 (en) * 2003-09-25 2005-09-01 David Bar-Or Methods and products which utilize N-acyl-L-aspartic acid
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
EP1734954A4 (de) * 2004-04-07 2007-05-30 Intervet Int Bv Wirksame zusammensetzung aus einem benzimidazol, avermectin und praziquantel und relevante anwendungsverfahren
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
DK2486942T3 (en) 2004-11-24 2019-01-28 Meda Pharmaceuticals Inc COMPOSITIONS CONTAINING AZELASTINE AND PROCEDURES FOR USING IT
CN1686089B (zh) * 2005-05-08 2010-08-18 北京健健康康生物技术有限公司 一种可直接压片的木糖醇颗粒及其制备方法
JP5373283B2 (ja) * 2005-07-08 2013-12-18 武田薬品工業株式会社 錠剤
US20070020186A1 (en) * 2005-07-22 2007-01-25 Alpex Pharma S.A. Solid dosage formulations of narcotic drugs having improved buccal adsorption
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
US20070128251A1 (en) * 2005-12-07 2007-06-07 Piedmont Pharmaceuticals, Inc. Process for manufacturing chewable dosage forms for drug delivery and products thereof
GB0601498D0 (en) 2006-01-25 2006-03-08 Probio Nutraceuticals As Product
FR2898056B1 (fr) 2006-03-01 2012-01-20 Ethypharm Sa Comprimes resistant a l'ecrasement destines a eviter le detournement illicite
US20070251352A1 (en) * 2006-05-01 2007-11-01 Pruitt Judith G Pelletized Feed Material for Biomass Generator
US20090269393A1 (en) * 2006-06-12 2009-10-29 Jubliant Organosys Limited Chewable Bilayer Tablet Formulation
WO2008094877A2 (en) * 2007-01-30 2008-08-07 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
KR101109633B1 (ko) 2007-08-03 2012-01-31 제이더블유중외제약 주식회사 활성성분의 코팅막이 보호되는 구강내붕해제형을 제조하기위한 조성물
USD616032S1 (en) * 2007-08-24 2010-05-18 Maraia Micah L Clip for identifying elongated objects
WO2009089134A1 (en) 2008-01-04 2009-07-16 Src, Inc. Methods for measuring a patint response upon administration of a drug and compositions thereof
US20100009012A1 (en) * 2008-07-11 2010-01-14 Zukkoor N David Chewable pharyngeal inflammation symptom relief composition
US20100190739A1 (en) * 2008-12-15 2010-07-29 Fleming And Company, Pharmaceuticals Rapidly Dissolving Vitamin Formulation and Methods of Using the Same
US20100278913A1 (en) * 2009-04-30 2010-11-04 Sancilio & Company Chewable tablet
AU330360S (en) * 2009-08-27 2010-04-14 Astrazeneca Ab Tablet
WO2011041414A1 (en) * 2009-09-30 2011-04-07 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
EP2509631A4 (de) * 2009-12-10 2014-04-02 Monosol Rx Llc Ph-empfindliche verbindungen für eine geschmacksverbergung in oral einnehmbaren dünnschichtstreifen
USD636070S1 (en) * 2010-02-26 2011-04-12 Astrazeneca Ab Tablet
USD632386S1 (en) * 2010-06-01 2011-02-08 Herbalife International of America Oral supplement
JP5771381B2 (ja) * 2010-10-22 2015-08-26 アサヒフードアンドヘルスケア株式会社 乾燥酵母を含有する錠剤
USD697510S1 (en) * 2011-03-23 2014-01-14 Brother Industries, Ltd. Scanner with projector
AU2012307656B2 (en) 2011-09-15 2016-07-07 Friulchem Spa Compositions for oral administration to animals, production methods thereof and uses of same
WO2014033230A1 (fr) 2012-08-31 2014-03-06 Friulchem Spa Compositions pour administration orale aux animaux, leurs procedes d'obtention et leurs utilisations
WO2013068371A1 (en) 2011-11-08 2013-05-16 Intervet International B.V. Soft chewable dosage form compositions of cannabinoid receptor type 1 (cb-1) antagonists
CN104168900A (zh) 2012-02-06 2014-11-26 梅里亚有限公司 包含全身性地起作用的活性剂的杀寄生虫口服兽用组合物、方法及其用途
BR112014024833B1 (pt) 2012-04-04 2022-10-04 Intervet International B.V. Produto farmacêutico veterinário mastigável macio, processo para sua fabricação e seu uso, bem como uso de pamoato de sódio
ES2748578T3 (es) 2012-06-15 2020-03-17 Pharmathen Sa Composición farmacéutica que contiene un polímero de unión a fosfato
US9532946B2 (en) * 2012-11-20 2017-01-03 Intervet Inc. Manufacturing of semi-plastic pharmaceutical dosage units
WO2014085599A1 (en) 2012-11-30 2014-06-05 Acura Pharmaceuticals, Inc. Self-regulated release of active pharmaceutical ingredient
US9642811B2 (en) 2014-03-26 2017-05-09 Sun Pharma Advanced Research Company Ltd. Abuse deterrent immediate release biphasic matrix solid dosage form
WO2016033424A1 (en) 2014-08-29 2016-03-03 Genzyme Corporation Methods for the prevention and treatment of major adverse cardiovascular events using compounds that modulate apolipoprotein b
CN104490804A (zh) * 2014-12-05 2015-04-08 海南卫康制药(潜山)有限公司 一种西咪替丁组合物咀嚼片及其制备方法
EP3061501A1 (de) 2015-02-27 2016-08-31 Rottapharm Ltd. Zusammensetzung zur behandlung von akne
EP3117825A1 (de) 2015-07-16 2017-01-18 Rottapharm S.p.A. Orale formulierung mit berberin und morus-alba-extrakt
US11103581B2 (en) 2015-08-31 2021-08-31 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
EP3389628A4 (de) * 2015-12-19 2019-08-07 Dixit, Manesh A. Pharmazeutische formulierungen in form von weichen kautabletten
US20190022013A1 (en) 2015-12-19 2019-01-24 First Time Us Generics Llc Soft-chew tablet pharmaceutical formulations
WO2017151571A1 (en) * 2016-02-29 2017-09-08 First Time Us Generics Llc Abuse deterrent soft chewable drug formulations
MX2018013816A (es) 2016-05-12 2019-03-21 Bayer Animal Health Gmbh Procedimiento para la preparacion de cuerpos moldeados para la administracion a animales.
US10323226B2 (en) 2017-03-30 2019-06-18 Nch Corporation Feed material for biomass generator
EP3646856B1 (de) * 2017-06-27 2023-11-22 Daiichi Sankyo Company, Limited Tablette
EP3878436A1 (de) 2020-03-09 2021-09-15 Bayer Animal Health GmbH Weicher kaubarer formkörper zur verabreichung an tiere
CA3124579C (en) 2020-07-15 2026-03-31 Schabar Research Associates Llc Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn
JP2023534810A (ja) 2020-07-15 2023-08-14 シャバー リサーチ アソシエイツ エルエルシー 急性痛の処置並びに胸やけの重症度及び/又はリスクの低減のための、イブプロフェン及びファモチジンから構成される単位経口用量組成物
US12514846B2 (en) 2020-07-15 2026-01-06 Schabar Research Associates Llc Unit oral dose compositions composed of ibuprofen or a pharmaceutically acceptable salt thereof and famotidine or a pharmaceutically acceptable salt thereof for the treatment of acute pain and the reduction of the severity and/or risk of heartburn and/or upset stomach
JP2023554665A (ja) 2020-12-18 2023-12-28 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド ホウ素含有ピラゾール化合物、それらを含む組成物、それらの方法及び使用
IT202100016310A1 (it) * 2021-06-22 2022-12-22 Alaia Idea S R L Metodo per la produzione di compresse
US20230123099A1 (en) * 2021-10-15 2023-04-20 Fertin Pharma A/S Dextrose tablets with improved mouthfeel
US20240130974A1 (en) * 2022-10-19 2024-04-25 Genexa Inc. Solid pharmaceutical tablet

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431339A (en) * 1966-07-20 1969-03-04 Colgate Palmolive Co Dentifrices
EP0180364A2 (de) * 1984-10-16 1986-05-07 Reckitt And Colman Products Limited Phenothiazine enthaltende Arzneimittel
EP0196546A2 (de) * 1985-03-25 1986-10-08 Abbott Laboratories Pharmazeutisches Tablettierverfahren
WO1991000096A1 (en) * 1988-05-31 1991-01-10 Amer Moh Samir Low-dosage sublingual aspirin
WO1995000121A1 (en) * 1993-06-18 1995-01-05 Novo Nordisk A/S Compressible enzyme powder
EP0636364A1 (de) * 1993-07-27 1995-02-01 McNEIL-PPC, INC. Schnellauflösliche pharmazeutische Dosierungsformen und Verfahren zu ihrer Herstellung
EP0717986A1 (de) * 1994-12-19 1996-06-26 McNEIL-PPC, INC. Rotogranulat und Beschichtung von Acetaminophen, Pseudoephedrin Chlorpheniramin und, gegebenenfalls, Dextromethorphan
US5536526A (en) * 1988-01-11 1996-07-16 Cultor Ltd. Xylitol-based binding and diluting agent and a process for the production thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3619292A (en) * 1968-07-15 1971-11-09 Penick & Ford Ltd Tablets and method of forming
US4760094A (en) * 1986-10-21 1988-07-26 American Home Products Corporation (Del.) Spray dried acetaminophen
US4851226A (en) * 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
US5275823A (en) * 1989-04-27 1994-01-04 Smith Kline & French Laboratories Ltd. Pharmaceutical compositions
US5075114A (en) 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
US5609883A (en) 1994-09-16 1997-03-11 Advanced Technology Pharmaceuticals Corporation Compressed tablet transitory lubricant system
US5686107A (en) * 1995-01-30 1997-11-11 Fmc Corporation Chewable pharmaceutical tablets
EP0910345B1 (de) * 1996-06-17 2002-02-13 Janssen Pharmaceutica N.V. Bikonvexe, rasch desintegrierende verabreichungsformen
US6024981A (en) 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
US6270790B1 (en) * 1998-08-18 2001-08-07 Mxneil-Ppc, Inc. Soft, convex shaped chewable tablets having reduced friability

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431339A (en) * 1966-07-20 1969-03-04 Colgate Palmolive Co Dentifrices
EP0180364A2 (de) * 1984-10-16 1986-05-07 Reckitt And Colman Products Limited Phenothiazine enthaltende Arzneimittel
EP0196546A2 (de) * 1985-03-25 1986-10-08 Abbott Laboratories Pharmazeutisches Tablettierverfahren
US5536526A (en) * 1988-01-11 1996-07-16 Cultor Ltd. Xylitol-based binding and diluting agent and a process for the production thereof
WO1991000096A1 (en) * 1988-05-31 1991-01-10 Amer Moh Samir Low-dosage sublingual aspirin
WO1995000121A1 (en) * 1993-06-18 1995-01-05 Novo Nordisk A/S Compressible enzyme powder
EP0636364A1 (de) * 1993-07-27 1995-02-01 McNEIL-PPC, INC. Schnellauflösliche pharmazeutische Dosierungsformen und Verfahren zu ihrer Herstellung
EP0717986A1 (de) * 1994-12-19 1996-06-26 McNEIL-PPC, INC. Rotogranulat und Beschichtung von Acetaminophen, Pseudoephedrin Chlorpheniramin und, gegebenenfalls, Dextromethorphan

Also Published As

Publication number Publication date
KR20000017352A (ko) 2000-03-25
US20030049316A1 (en) 2003-03-13
EP0997143A2 (de) 2000-05-03
AU4456599A (en) 2000-03-09
CN1249176A (zh) 2000-04-05
PT997143E (pt) 2008-02-07
NZ337310A (en) 2000-05-26
US7029699B2 (en) 2006-04-18
SA99200655B1 (ar) 2006-08-22
AU773549B2 (en) 2004-05-27
DE69937780D1 (de) 2008-01-31
CA2280628A1 (en) 2000-02-18
US6471991B2 (en) 2002-10-29
CA2280628C (en) 2009-02-10
EP0997143B1 (de) 2007-12-19
ZA995248B (en) 2001-02-19
BR9903736A (pt) 2000-09-26
CO5130019A1 (es) 2002-02-27
AR022065A1 (es) 2002-09-04
ES2299234T3 (es) 2008-05-16
ATE381320T1 (de) 2008-01-15
DE69937780T2 (de) 2008-12-04
JP2000095673A (ja) 2000-04-04
US20010043947A1 (en) 2001-11-22
US6270790B1 (en) 2001-08-07

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