EP1001990A4 - Trail bindendes protein - Google Patents

Trail bindendes protein

Info

Publication number
EP1001990A4
EP1001990A4 EP98931713A EP98931713A EP1001990A4 EP 1001990 A4 EP1001990 A4 EP 1001990A4 EP 98931713 A EP98931713 A EP 98931713A EP 98931713 A EP98931713 A EP 98931713A EP 1001990 A4 EP1001990 A4 EP 1001990A4
Authority
EP
European Patent Office
Prior art keywords
protein
binds trail
trail
binds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98931713A
Other languages
English (en)
French (fr)
Other versions
EP1001990A1 (de
Inventor
Henning Walczak
Craig A Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of EP1001990A1 publication Critical patent/EP1001990A1/de
Publication of EP1001990A4 publication Critical patent/EP1001990A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP98931713A 1997-06-26 1998-06-25 Trail bindendes protein Withdrawn EP1001990A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88352997A 1997-06-26 1997-06-26
US883529 1997-06-26
PCT/US1998/013491 WO1999000423A1 (en) 1997-06-26 1998-06-25 Protein that binds trail

Publications (2)

Publication Number Publication Date
EP1001990A1 EP1001990A1 (de) 2000-05-24
EP1001990A4 true EP1001990A4 (de) 2001-12-19

Family

ID=25382755

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98931713A Withdrawn EP1001990A4 (de) 1997-06-26 1998-06-25 Trail bindendes protein

Country Status (7)

Country Link
EP (1) EP1001990A4 (de)
JP (1) JP2002507127A (de)
AU (1) AU756759B2 (de)
CA (1) CA2294704A1 (de)
IL (1) IL133602A0 (de)
NZ (1) NZ501831A (de)
WO (1) WO1999000423A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69834027D1 (de) 1997-01-14 2006-05-18 Human Genome Sciences Inc Tumor-nekrose-faktor rezeptor 5
US6455040B1 (en) 1997-01-14 2002-09-24 Human Genome Sciences, Inc. Tumor necrosis factor receptor 5
US6313269B1 (en) * 1997-03-14 2001-11-06 Smithkline Beecham Corporation Tumor necrosis factor related receptor, TR6
US6872568B1 (en) 1997-03-17 2005-03-29 Human Genome Sciences, Inc. Death domain containing receptor 5 antibodies
ES2281126T3 (es) 1997-03-17 2007-09-16 Human Genome Sciences, Inc. Receptor 5 que contiene un dominio de muerte.
AU5022400A (en) * 1999-05-20 2000-12-12 Human Genome Sciences, Inc. Tumor necrosis factor receptor 5
KR100436089B1 (ko) * 2000-07-06 2004-06-14 설대우 분비성 재조합 트라이머형의 트레일 단백질 생산을 위한 디엔에이 카세트, 테트라사이클린/독시사이클린-유도성아데노-관련 바이러스 벡터, 이 둘의 조합, 및 이들을이용한 유전자 치료
US7361341B2 (en) 2001-05-25 2008-04-22 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to trail receptors
US7348003B2 (en) 2001-05-25 2008-03-25 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors
JP4309758B2 (ja) 2001-05-25 2009-08-05 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド Ｔｒａｉｌレセプターに免疫特異的に結合する抗体
IL161296A0 (en) * 2001-10-13 2004-09-27 Asterion Ltd Glycosylphosphatidylinositol containing polypeptides
RU2340628C2 (ru) * 2001-10-13 2008-12-10 Астерион Лимитед Слитый белок, ингибирующий рецепторную передачу сигнала гормона роста (варианты), способ его получения и очистки и фармацевтическая композиция на его основе
ZA200606913B (en) 2004-03-11 2008-03-26 Genentech Inc Process for producing polypeptides
WO2015138638A1 (en) 2014-03-11 2015-09-17 Theraly Pharmaceuticals, Inc. Long acting trail receptor agonists for treatment of autoimmune diseases
JP6797203B2 (ja) 2015-12-17 2020-12-09 ザ・ジョンズ・ホプキンス・ユニバーシティー デスレセプターアゴニストによる全身性硬化症の改善
KR102508650B1 (ko) 2016-04-07 2023-03-13 더 존스 홉킨스 유니버시티 사멸 수용체 작용제로써 췌장암 및 통증을 치료하기 위한 조성물 및 방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998030693A2 (en) * 1997-01-14 1998-07-16 Human Genome Sciences, Inc. Tumor necrosis factor receptor 5
EP0867509A2 (de) * 1997-02-05 1998-09-30 Smithkline Beecham Corporation Tumornekrosis bezohener Rezeptor, TR5
WO1998058062A1 (en) * 1997-06-18 1998-12-23 Genentech, Inc. Apo-2DcR

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998030693A2 (en) * 1997-01-14 1998-07-16 Human Genome Sciences, Inc. Tumor necrosis factor receptor 5
EP0867509A2 (de) * 1997-02-05 1998-09-30 Smithkline Beecham Corporation Tumornekrosis bezohener Rezeptor, TR5
WO1998058062A1 (en) * 1997-06-18 1998-12-23 Genentech, Inc. Apo-2DcR

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9900423A1 *
WILEY S R ET AL: "Identification and characterization of a new member of the TNF family that induces apoptosis", IMMUNITY, CELL PRESS, US, vol. 3, no. 6, 1 December 1995 (1995-12-01), pages 673 - 682, XP000672297, ISSN: 1074-7613 *

Also Published As

Publication number Publication date
EP1001990A1 (de) 2000-05-24
WO1999000423A1 (en) 1999-01-07
CA2294704A1 (en) 1999-01-07
AU756759B2 (en) 2003-01-23
AU8175898A (en) 1999-01-19
IL133602A0 (en) 2001-04-30
JP2002507127A (ja) 2002-03-05
NZ501831A (en) 2001-09-28

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Legal Events

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Owner name: IMMUNEX CORPORATION

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Inventor name: SMITH, CRAIG, A.

Inventor name: WALCZAK, HENNING

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