EP1007076A4 - Procede permettant d'antagoniser le domaine humain src sh2 - Google Patents

Procede permettant d'antagoniser le domaine humain src sh2

Info

Publication number
EP1007076A4
EP1007076A4 EP98910294A EP98910294A EP1007076A4 EP 1007076 A4 EP1007076 A4 EP 1007076A4 EP 98910294 A EP98910294 A EP 98910294A EP 98910294 A EP98910294 A EP 98910294A EP 1007076 A4 EP1007076 A4 EP 1007076A4
Authority
EP
European Patent Office
Prior art keywords
antagonizing
domain
human src
src
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98910294A
Other languages
German (de)
English (en)
Other versions
EP1007076A1 (fr
Inventor
Dennis A Holt
Daniel F Veber
Dennis S Yamashita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1007076A1 publication Critical patent/EP1007076A1/fr
Publication of EP1007076A4 publication Critical patent/EP1007076A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP98910294A 1997-03-10 1998-03-10 Procede permettant d'antagoniser le domaine humain src sh2 Withdrawn EP1007076A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4065897P 1997-03-10 1997-03-10
US40658P 1997-03-10
PCT/US1998/004699 WO1998040093A1 (fr) 1997-03-10 1998-03-10 Procede permettant d'antagoniser le domaine humain src sh2

Publications (2)

Publication Number Publication Date
EP1007076A1 EP1007076A1 (fr) 2000-06-14
EP1007076A4 true EP1007076A4 (fr) 2004-10-27

Family

ID=21912217

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98910294A Withdrawn EP1007076A4 (fr) 1997-03-10 1998-03-10 Procede permettant d'antagoniser le domaine humain src sh2

Country Status (4)

Country Link
EP (1) EP1007076A4 (fr)
JP (1) JP2001514662A (fr)
CA (1) CA2283472A1 (fr)
WO (1) WO1998040093A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999024442A1 (fr) 1997-11-12 1999-05-20 Ariad Pharmaceuticals, Inc. Nouveaux inhibiteurs de transduction de signal, compositions les contenant

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995025118A2 (fr) * 1994-03-15 1995-09-21 Trustees Of Tufts University Inhibiteurs d'interactions des domaines sh2
EP0727211A1 (fr) * 1995-02-10 1996-08-21 Smithkline Beecham Corporation Emploi de composés spécifiques src SH2 dans le traitement de maladies de résorption osseuse

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995025118A2 (fr) * 1994-03-15 1995-09-21 Trustees Of Tufts University Inhibiteurs d'interactions des domaines sh2
EP0727211A1 (fr) * 1995-02-10 1996-08-21 Smithkline Beecham Corporation Emploi de composés spécifiques src SH2 dans le traitement de maladies de résorption osseuse

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DUNNINGTON E.A.: "Inhibition of bone resorption by src SH2 domain antagonists", J.BONE.MIN.RES., vol. 11, 1996, pages S398, XP008034025 *
See also references of WO9840093A1 *

Also Published As

Publication number Publication date
WO1998040093A1 (fr) 1998-09-17
EP1007076A1 (fr) 2000-06-14
CA2283472A1 (fr) 1998-09-17
JP2001514662A (ja) 2001-09-11

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19990908

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): BE CH DE ES FR GB IT LI NL

A4 Supplementary search report drawn up and despatched

Effective date: 20040909

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 07K 7/06 B

Ipc: 7A 01N 43/30 B

Ipc: 7A 01N 43/16 B

Ipc: 7A 01N 43/08 B

Ipc: 7A 01N 43/02 B

Ipc: 7A 61K 38/05 A

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20041124