EP1009405A4 - Payrrolidine und piperidine modulatoren der chemokine rezeptoraktivitaet - Google Patents
Payrrolidine und piperidine modulatoren der chemokine rezeptoraktivitaetInfo
- Publication number
- EP1009405A4 EP1009405A4 EP98944548A EP98944548A EP1009405A4 EP 1009405 A4 EP1009405 A4 EP 1009405A4 EP 98944548 A EP98944548 A EP 98944548A EP 98944548 A EP98944548 A EP 98944548A EP 1009405 A4 EP1009405 A4 EP 1009405A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- pyrrolidine
- modulators
- piperidine
- chemokine receptor
- receptor activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5774397P | 1997-08-28 | 1997-08-28 | |
| US57743P | 1997-08-28 | ||
| GB9801009 | 1998-01-16 | ||
| GBGB9801009.3A GB9801009D0 (en) | 1998-01-16 | 1998-01-16 | Pyrrolidine and piperidine modulators of chemokine receptor activity |
| PCT/US1998/017755 WO1999009984A1 (en) | 1997-08-28 | 1998-08-27 | Pyrrolidine and piperidine modulators of chemokine receptor activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1009405A1 EP1009405A1 (de) | 2000-06-21 |
| EP1009405A4 true EP1009405A4 (de) | 2001-05-09 |
Family
ID=26312970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP98944548A Withdrawn EP1009405A4 (de) | 1997-08-28 | 1998-08-27 | Payrrolidine und piperidine modulatoren der chemokine rezeptoraktivitaet |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1009405A4 (de) |
| JP (1) | JP2001526178A (de) |
| AU (1) | AU9206798A (de) |
| CA (1) | CA2298813A1 (de) |
| WO (1) | WO1999009984A1 (de) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6743594B1 (en) | 1995-06-06 | 2004-06-01 | Human Genome Sciences, Inc. | Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5) |
| US6025154A (en) | 1995-06-06 | 2000-02-15 | Human Genome Sciences, Inc. | Polynucleotides encoding human G-protein chemokine receptor HDGNR10 |
| CA2347912A1 (en) * | 1998-12-18 | 2000-06-22 | Soo S. Ko | Heterocyclic piperidines as modulators of chemokine receptor activity |
| EP1013276A1 (de) | 1998-12-23 | 2000-06-28 | Pfizer Inc. | Aminoazacycloalkane als CCR5-Modulatoren |
| PE20001420A1 (es) | 1998-12-23 | 2000-12-18 | Pfizer | Moduladores de ccr5 |
| US7217714B1 (en) | 1998-12-23 | 2007-05-15 | Agouron Pharmaceuticals, Inc. | CCR5 modulators |
| AU3389300A (en) * | 1999-03-02 | 2000-09-21 | Merck & Co., Inc. | Pyrrolidine modulators of chemokine receptor activity |
| US6489354B1 (en) * | 1999-03-02 | 2002-12-03 | Merck & Co., Inc. | 3-alkyl substituted pyrrolidine modulators of chemokine receptor activity |
| US6303593B1 (en) * | 1999-03-02 | 2001-10-16 | Merck & Co., Inc. | 3-thienyl and 3-furanyl pyrrolidine modulators of chemokine receptor activity |
| US6248755B1 (en) | 1999-04-06 | 2001-06-19 | Merck & Co., Inc. | Pyrrolidine modulators of chemokine receptor activity |
| US6498161B1 (en) | 1999-04-06 | 2002-12-24 | Merck & Co., Inc. | Pyrrolidine modulators of chemokine receptor activity |
| US6265434B1 (en) * | 1999-04-06 | 2001-07-24 | Merck & Co., Inc. | Pyrrolidine modulators of chemokine receptor activity |
| US6399619B1 (en) | 1999-04-06 | 2002-06-04 | Merck & Co., Inc. | Pyrrolidine modulators of chemokine receptor activity |
| GB9912701D0 (en) * | 1999-06-01 | 1999-08-04 | Smithkline Beecham Plc | Novel compounds |
| AU5600100A (en) | 1999-06-11 | 2001-01-02 | Merck & Co., Inc. | Cyclopentyl modulators of chemokine receptor activity |
| DE60031676T2 (de) * | 1999-06-11 | 2007-08-30 | Merck & Co., Inc. | N-cyclopentylmodulatoren der chemokine rezeptoraktivität |
| US6472410B1 (en) | 1999-06-11 | 2002-10-29 | Merck & Co., Inc. | N-cyclopentyl modulators of chemokine receptor activity |
| US6500844B1 (en) | 1999-06-11 | 2002-12-31 | Merck & Co., Inc. | Cyclopentyl modulators of chemokine receptor activity |
| WO2000076513A1 (en) | 1999-06-11 | 2000-12-21 | Merck & Co., Inc. | Cyclopentyl modulators of chemokine receptor activity |
| AU5469400A (en) | 1999-06-11 | 2001-01-02 | Merck & Co., Inc. | Cyclopentyl modulators of chemokine receptor activity |
| US6358979B1 (en) | 1999-06-11 | 2002-03-19 | Merck & Co., Inc. | N-cyclopentyl modulators of chemokine receptor activity |
| AU2001239885A1 (en) * | 2000-02-28 | 2001-09-12 | Merck And Co., Inc. | 4-alkyl piperidinyl pyrrolidine modulators of chemokine receptor activity |
| MXPA02012712A (es) | 2000-06-30 | 2003-04-25 | Bristol Myers Squibb Pharma Co | N-ureidoheterocicloalquil-piperidinas como moduladores de la actividad del receptor de quimiocinas. |
| US6531484B2 (en) | 2000-10-11 | 2003-03-11 | Merck & Co., Inc. | Pyrrolidine modulators of CCR5 chemokine receptor activity |
| US7175988B2 (en) | 2001-02-09 | 2007-02-13 | Human Genome Sciences, Inc. | Human G-protein Chemokine Receptor (CCR5) HDGNR10 |
| GEP20053710B (en) | 2001-02-28 | 2005-12-26 | Merck & Co Inc | Acylated Piperidine Derivatives as Melanocortin-4 Receptor Agonists |
| EP1372653B1 (de) | 2001-02-28 | 2006-10-04 | Merck & Co., Inc. | Acylierte piperidin-derivate als melanocortin-4-rezeptor-agonisten |
| MXPA03008109A (es) | 2001-03-07 | 2003-12-12 | Pfizer Prod Inc | Moduladores de la actividad de receptores de quimiocinas. |
| GB0108099D0 (en) * | 2001-03-30 | 2001-05-23 | Hoffmann La Roche | Aminopiperidine derivatives |
| BR0209129A (pt) * | 2001-04-18 | 2005-12-20 | Euro Celtique Sa | Compostos, composições farmacêuticas, métodos para tratamento de dores, métodos para modulação de uma resposta farmacológica e usos de compostos |
| US7115628B2 (en) | 2001-07-18 | 2006-10-03 | Merck & Co., Inc. | Bridged piperidine derivatives as melanocortin receptor agonists |
| US7393934B2 (en) | 2001-12-21 | 2008-07-01 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor (CCR5) HDGNR10 |
| MXPA04012393A (es) | 2002-06-12 | 2005-06-17 | Chemocentryx | Derivados de piperazina 1-aril-4-substituidos para utilizar como antagonistas ccr1 para tratamiento de inflamacion y desordenes inmunes. |
| US7842693B2 (en) | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
| US7589199B2 (en) | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
| WO2004024720A1 (en) | 2002-09-11 | 2004-03-25 | Merck & Co., Inc. | Piperazine urea derivatives as melanocortin-4 receptor agonists |
| EP1633343A1 (de) * | 2003-05-30 | 2006-03-15 | Neuromed Technologies, Inc. | 3-aminomethylpyrrolidine als calciumkanalantagonisten vom n-typ |
| CA2579608A1 (en) | 2003-09-10 | 2005-03-17 | Virochem Pharma Inc. | Spiro compounds and methods for the modulation of chemokine receptor activity |
| GB0328906D0 (en) * | 2003-12-12 | 2004-01-14 | Syngenta Participations Ag | Chemical compounds |
| US7435831B2 (en) | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
| CN1950082B (zh) | 2004-03-03 | 2013-02-06 | 凯莫森特里克斯股份有限公司 | 双环和桥连的含氮杂环化物 |
| CA2559809A1 (en) | 2004-03-12 | 2005-11-10 | Human Genome Sciences, Inc. | Antibodies against human g-protein chemokine receptor (ccr5) hdgnr10 |
| KR20070046929A (ko) * | 2004-08-19 | 2007-05-03 | 버텍스 파마슈티칼스 인코포레이티드 | 무스카린 수용체 조절제 |
| BRPI0519288A2 (pt) * | 2004-12-24 | 2009-01-06 | Astrazeneca Ab | compostos heterocÍclicos como antagonistas de ccr2b |
| US7880002B2 (en) | 2004-12-29 | 2011-02-01 | Millennium Pharmaceuticals, Inc. | Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists |
| US7635698B2 (en) | 2004-12-29 | 2009-12-22 | Millennium Pharmaceuticals, Inc. | Compounds useful as chemokine receptor antagonists |
| WO2006073361A1 (en) * | 2005-01-06 | 2006-07-13 | Astrazeneca Ab | Novel pyridine compounds |
| GB0505969D0 (en) | 2005-03-23 | 2005-04-27 | Novartis Ag | Organic compounds |
| GB0514203D0 (en) | 2005-07-11 | 2005-08-17 | Novartis Ag | Organic compounds |
| GB0525957D0 (en) | 2005-12-21 | 2006-02-01 | Astrazeneca Ab | Methods |
| JP2009521483A (ja) * | 2005-12-22 | 2009-06-04 | バーテックス ファーマシューティカルズ インコーポレイテッド | ムスカリン受容体のモジュレーター |
| NZ569135A (en) | 2005-12-30 | 2011-08-26 | Novartis Ag | 3,5-Substituted piperidine compounds as renin inhibitors |
| US7351706B2 (en) | 2006-01-05 | 2008-04-01 | Hoffmann-La Roche Inc. | Indol-3-yl-carbonyl-spiro-piperidine derivatives |
| EP1987034B1 (de) * | 2006-02-22 | 2011-07-20 | Vertex Pharmceuticals Incorporated | Kondensierte spiropiperidine als modulatoren muskarinartiger rezeptoren |
| EP2027086B1 (de) | 2006-05-19 | 2011-11-16 | Wyeth LLC | N-benzoypyrrolidin-3-ylamine als histamin-3 antagonisten |
| US7727978B2 (en) | 2006-08-24 | 2010-06-01 | Bristol-Myers Squibb Company | Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| WO2009000811A1 (en) | 2007-06-25 | 2008-12-31 | Novartis Ag | N5-(2-ethoxyethyl)-n3-(2-pyridinyl)-3,5-piperidinedicarboxamide derivatives for use as renin inhibitors |
| US8119658B2 (en) | 2007-10-01 | 2012-02-21 | Bristol-Myers Squibb Company | Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| JP5580741B2 (ja) | 2008-09-19 | 2014-08-27 | 武田薬品工業株式会社 | 含窒素複素環化合物およびその用途 |
| AU2021222441A1 (en) | 2020-02-19 | 2022-09-22 | Ichilov Tech Ltd. | Improved antidepressant therapy |
| US20260014143A1 (en) * | 2022-07-21 | 2026-01-15 | The Regents Of The University Of California | Prostaglandin E synthase 3 (PTGES3) Inhibiting Compounds |
| CN115448864B (zh) * | 2022-08-26 | 2023-12-22 | 上海方予健康医药科技有限公司 | 3-氟-3-（1-羟乙基）吡咯烷-1-羧酸叔丁酯的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635510A (en) * | 1993-05-06 | 1997-06-03 | Merrell Pharmaceuticals Inc. | Substituted pyrrolidin-3-yl-alkyl-piperidines |
-
1998
- 1998-08-27 CA CA002298813A patent/CA2298813A1/en not_active Abandoned
- 1998-08-27 EP EP98944548A patent/EP1009405A4/de not_active Withdrawn
- 1998-08-27 JP JP2000507374A patent/JP2001526178A/ja active Pending
- 1998-08-27 WO PCT/US1998/017755 patent/WO1999009984A1/en not_active Ceased
- 1998-08-27 AU AU92067/98A patent/AU9206798A/en not_active Abandoned
Non-Patent Citations (2)
| Title |
|---|
| No further relevant documents disclosed * |
| See also references of WO9909984A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2298813A1 (en) | 1999-03-04 |
| WO1999009984A1 (en) | 1999-03-04 |
| AU9206798A (en) | 1999-03-16 |
| EP1009405A1 (de) | 2000-06-21 |
| JP2001526178A (ja) | 2001-12-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1173170A4 (de) | Pyrrolidinverbindungen als modulatoren der aktivität der chemokinrezeptoren | |
| EP1171122A4 (de) | Pyrrolidine als modulatoren der aktivität vom chemokinrezeptor | |
| EP0859614A4 (de) | Inhibitor der rotamase-enzymaktivität | |
| EP1003743A4 (de) | 3,3-disbstituierte piperidine wie modulatoren von chemokine-rezeptor aktivität | |
| EP0989822A4 (de) | Methoden und vorrichtungen zur verschaffung akustischer hemostasis | |
| DE69620930D1 (de) | Platte und Stift | |
| DE69635339D1 (de) | Elektromagnetisch-akustischer Wandler und EMAR-System | |
| DE69620381D1 (de) | Spielvorrichtung und system dafür | |
| EP1018987A4 (de) | Neo-knorpel und seine gebrauchsverfahren | |
| DE69635607D1 (de) | Liposom-verstärkter immunoaggregations-test und testvorrichtung | |
| DE69534362D1 (de) | Volloptischer mehrkanaliger TDM-WDM Konverter und volloptischer mehrkanaliger Zeit-Demultiplexer | |
| EP1003514A4 (de) | Cyclische amine modulatoren der chemokinrezeptoren | |
| NO973756D0 (no) | Deteksjon av stemmeaktivitet | |
| EP1558250A4 (de) | Gamma-aminoamid-modulatoren der chemokin-rezeptor-aktivitüt | |
| IT1275903B1 (it) | Esteri e ammidi della 1,4-piperidina disostituita | |
| EP1622916A4 (de) | Heterocyclische cyclopentyltetrahydroisochinolin- und -tetrahydropyridopyridinmodulatoren der chemokinrezeptoraktivität | |
| EP1558599A4 (de) | Heteroarylpiperidinmodulatoren derchemokinrezeptoraktivitüt | |
| DK0804078T3 (da) | Sammensætning og anvendelse deraf | |
| EP1015430A4 (de) | Spiro (prrolidin-2,3'-oxoindol)-verbindungen und verfahren zu ihrer anwendung | |
| PT806955E (pt) | Solucoes de injeccao e perfusao de enrofloxacina | |
| BR9708677A (pt) | Piperidinas e pirrolidinas | |
| FI960425L (fi) | Fenyylisykloheksyylikarboksyylihappoamidien käyttö | |
| FI953736A0 (fi) | I en bastugn anvaendbar foeraongnings och befuktingsanordning | |
| GB2325223B (en) | Novel antiatherosclerosis agents for lipid-lowering and antiperoxidative activity | |
| GB9801009D0 (en) | Pyrrolidine and piperidine modulators of chemokine receptor activity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20000328 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
| AX | Request for extension of the european patent |
Free format text: AL PAYMENT 20000328;LT PAYMENT 20000328;LV PAYMENT 20000328;MK PAYMENT 20000328;RO PAYMENT 20000328;SI PAYMENT 20000328 |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20010327 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
| RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7A 61K 31/47 A, 7A 61K 31/55 B, 7A 61K 31/435 B, 7A 61K 31/445 B, 7A 61K 31/495 B, 7C 07D 211/68 B, 7C 07D 217/02 B, 7C 07D 223/16 B, 7C 07D 401/06 B, 7C 07D 403/06 B, 7C 07D 495/10 B, 7C 07D 409/14 B, 7C 07D 401/14 B, 7C 07D 417/14 B, 7C 07D 413/14 B, 7C 07D 207/09 B, 7C 07D 405/14 B, 7A 61P 31/18 B, 7C 07D 211/26 B |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20020301 |