EP1032583A4 - Aktive immunisierung gegen durch angiogenese hervorgerufene antigene - Google Patents

Aktive immunisierung gegen durch angiogenese hervorgerufene antigene

Info

Publication number
EP1032583A4
EP1032583A4 EP99911258A EP99911258A EP1032583A4 EP 1032583 A4 EP1032583 A4 EP 1032583A4 EP 99911258 A EP99911258 A EP 99911258A EP 99911258 A EP99911258 A EP 99911258A EP 1032583 A4 EP1032583 A4 EP 1032583A4
Authority
EP
European Patent Office
Prior art keywords
angiotens
immunization against
active immunization
active
immunization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99911258A
Other languages
English (en)
French (fr)
Other versions
EP1032583A1 (de
Inventor
Daniel J Hicklin
Soldano Ferrone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York Medical College
ImClone LLC
Original Assignee
New York Medical College
ImClone Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Medical College, ImClone Systems Inc filed Critical New York Medical College
Publication of EP1032583A1 publication Critical patent/EP1032583A1/de
Publication of EP1032583A4 publication Critical patent/EP1032583A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/19Dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24Antigen-presenting cells [APC]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4244Enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP99911258A 1998-03-06 1999-03-08 Aktive immunisierung gegen durch angiogenese hervorgerufene antigene Withdrawn EP1032583A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3672498A 1998-03-06 1998-03-06
US36724 1998-03-06
PCT/US1999/005164 WO1999045018A1 (en) 1998-03-06 1999-03-08 Active immunization against angiogenesis-associated antigens

Publications (2)

Publication Number Publication Date
EP1032583A1 EP1032583A1 (de) 2000-09-06
EP1032583A4 true EP1032583A4 (de) 2005-02-02

Family

ID=21890263

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99911258A Withdrawn EP1032583A4 (de) 1998-03-06 1999-03-08 Aktive immunisierung gegen durch angiogenese hervorgerufene antigene

Country Status (4)

Country Link
EP (1) EP1032583A4 (de)
AU (1) AU2994599A (de)
CA (1) CA2310252A1 (de)
WO (1) WO1999045018A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010102556A (ko) * 1999-03-11 2001-11-15 추후제출 암 및 과증식성 장애의 치료 조성물 및 치료방법
FR2796073B1 (fr) * 1999-07-07 2003-08-29 Centre Nat Rech Scient Anticorps anti-idiotypiques des facteurs de croissance des fibroblastes et leur utilisation comme medicaments
US7087592B1 (en) 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
US7094410B2 (en) 2002-03-02 2006-08-22 The Scripps Research Institute DNA vaccine against proliferating endothelial cells and methods of use thereof
CU23178A1 (es) * 2002-04-15 2006-09-22 Ct Ingenieria Genetica Biotech INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA
KR20050047518A (ko) * 2002-07-05 2005-05-20 듀크 유니버시티 혈관 면역요법
EP1633367A2 (de) 2003-05-28 2006-03-15 EntreMed, Inc. Antiangiogene mittel
CA2558014A1 (en) 2004-03-12 2005-09-29 Entremed, Inc. Antiangiogenic agents
CA2646065C (en) 2006-03-20 2014-01-14 Entremed, Inc. Disease modifying anti-arthritic activity of 2-methoxyestradiol
WO2008006187A2 (en) * 2006-07-12 2008-01-17 Legeev, Yury V. Protein complexes for prevention and treatment of diseases with angiogenesis disorders
CU24637B1 (es) 2019-12-24 2022-12-12 Ct Ingenieria Genetica Biotecnologia Polipéptidos que comprenden mutantes del vegf-a humano con re-arreglos de puentes disulfuro y composiciones que los contienen

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0438803A2 (de) * 1990-01-26 1991-07-31 Immunomedics, Inc. Impfstoffe gegen Krebs und Infektionskrankheiten
WO1994005329A1 (en) * 1992-08-31 1994-03-17 Jenner Technologies Stimulation of an antitumor t-cell response using anti-idiotypic antibodies
WO1997023510A1 (fr) * 1995-12-21 1997-07-03 Centre National De La Recherche Scientifique Anticorps anti-idiotypiques du facteur de croissance endotheliale vasculaire et leur utilisation comme medicaments
WO1997023237A1 (en) * 1995-12-22 1997-07-03 Immunomedics, Inc. Use of immunoconjugates to enhance the efficacy of multi-stage cascade boosting vaccines

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1979000160A1 (en) * 1977-09-28 1979-04-05 Nat Res Dev Improvements in or relating to immunological preparations
US4778752A (en) * 1983-10-11 1988-10-18 Scripps Clinic And Research Foundation Receptors specific for hapten-modified self proteins
US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
KR920703114A (ko) * 1989-07-14 1992-12-17 원본미기재 접합체 백신을 위한 시토킨 및 호르몬 운반체
US5965132A (en) * 1992-03-05 1999-10-12 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
WO1993022343A1 (en) * 1992-05-01 1993-11-11 The Rockfeller University Multiple antigen peptide system having adjuvant properties and vaccines prepared therefrom

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0438803A2 (de) * 1990-01-26 1991-07-31 Immunomedics, Inc. Impfstoffe gegen Krebs und Infektionskrankheiten
WO1994005329A1 (en) * 1992-08-31 1994-03-17 Jenner Technologies Stimulation of an antitumor t-cell response using anti-idiotypic antibodies
WO1997023510A1 (fr) * 1995-12-21 1997-07-03 Centre National De La Recherche Scientifique Anticorps anti-idiotypiques du facteur de croissance endotheliale vasculaire et leur utilisation comme medicaments
WO1997023237A1 (en) * 1995-12-22 1997-07-03 Immunomedics, Inc. Use of immunoconjugates to enhance the efficacy of multi-stage cascade boosting vaccines

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
MARUYAMA HARUHIKO ET AL: "Monoclonal anti-idiotypic antibody functionally mimics the human gastrointestinal carcinoma epitope GA733", INTERNATIONAL JOURNAL OF CANCER, vol. 65, no. 4, 1996, pages 547 - 553, XP008039311, ISSN: 0020-7136 *
ORTEGA N ET AL: "MODULATION DE LA PROGRESSION TUMORALE PAR DES ANTICORPS ANTI-IDIOTYPIQUES DE FACTEURS ANGIOGENIQUES. MODULATION OF TUMOR PROGRESSION BY ANTI-IDIOTYPIC ANTIBODIES OF ANGIOGENIC FACTORS", COMPTES RENDUS DES SEANCES DE L'ACADEMIE DES SCIENCES. SERIE III: SCIENCES DE LA VIE, ELSEVIER, AMSTERDAM, NL, vol. 319, no. 5, 1 May 1996 (1996-05-01), pages 411 - 415, XP000601935, ISSN: 0764-4469 *
PLOUET J ET AL: "VEGF DEPENDENT TUMORAL PROGRESSION: SITMULATION BY ANTI VEGF IDIOTYPIC ANTIBODIES", JOURNAL OF CELLULAR BIOCHEMISTRY. SUPPLEMENT, A.R. LISS, NEW YORK, NY, US, no. SUPPL 18A, January 1994 (1994-01-01), pages 328, XP000602723, ISSN: 0733-1959 *
See also references of WO9945018A1 *

Also Published As

Publication number Publication date
CA2310252A1 (en) 1999-09-10
EP1032583A1 (de) 2000-09-06
AU2994599A (en) 1999-09-20
WO1999045018A1 (en) 1999-09-10

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