EP1075184A4 - Zusammensetzungen und verfahren zur aktiven impfung - Google Patents

Zusammensetzungen und verfahren zur aktiven impfung

Info

Publication number: EP1075184A4
Authority: EP; European Patent Office
Prior art keywords: compositions; methods; active vaccination; vaccination; active
Prior art date: 1998-05-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP99921790A

Other languages

English (en)

French (fr)

Other versions

EP1075184A1 (de

Inventor

David B Agus

David Scheinberg

Wendy Roberts

Andrew D Zelenetz

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Memorial Sloan Kettering Cancer Center

Original Assignee

Memorial Sloan Kettering Cancer Center

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-08

Filing date

1999-05-07

Publication date

2002-01-30

1999-05-07 Application filed by Memorial Sloan Kettering Cancer Center filed Critical Memorial Sloan Kettering Cancer Center

2001-02-14 Publication of EP1075184A1 publication Critical patent/EP1075184A1/de

2002-01-30 Publication of EP1075184A4 publication Critical patent/EP1075184A4/de

Status Withdrawn legal-status Critical Current

Links

238000000034 method Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
238000002255 vaccination Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001103—Receptors for growth factors
- A61K39/001104—Epidermal growth factor receptors [EGFR]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001103—Receptors for growth factors
- A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001103—Receptors for growth factors
- A61K39/001109—Vascular endothelial growth factor receptors [VEGFR]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001111—Immunoglobulin superfamily
- A61K39/001112—CD19 or B4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001116—Receptors for cytokines
- A61K39/001119—Receptors for interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001124—CD20
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Immunology (AREA)
Oncology (AREA)
Cell Biology (AREA)
Organic Chemistry (AREA)
Vascular Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Dermatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)

EP99921790A 1998-05-08 1999-05-07 Zusammensetzungen und verfahren zur aktiven impfung Withdrawn EP1075184A4 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US8487098P	1998-05-08	1998-05-08
US84870P		1998-05-08
PCT/US1999/010065 WO1999057981A1 (en)	1998-05-08	1999-05-07	Compositions and methods for active vaccination

Publications (2)

Publication Number	Publication Date
EP1075184A1 EP1075184A1 (de)	2001-02-14
EP1075184A4 true EP1075184A4 (de)	2002-01-30

Family

ID=22187732

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP99921790A Withdrawn EP1075184A4 (de)	1998-05-08	1999-05-07	Zusammensetzungen und verfahren zur aktiven impfung

Country Status (4)

Country	Link
EP (1)	EP1075184A4 (de)
JP (1)	JP2002514573A (de)
CA (1)	CA2330212A1 (de)
WO (1)	WO1999057981A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7198920B1 (en)	1999-01-29	2007-04-03	Corika Corporation	HER-2/neu fusion proteins
IL152054A0 (en)	2000-04-13	2003-05-29	Bio Life Science Forschungs & Entwicklungsgesellschaft Mbh	Vaccine against cancerous diseases which is based on mimotopes of antigens expressed on tumor cells
US7229623B1 (en)	2000-08-03	2007-06-12	Corixa Corporation	Her-2/neu fusion proteins
US6911204B2 (en)	2000-08-11	2005-06-28	Favrille, Inc.	Method and composition for altering a B cell mediated pathology
MXPA03001389A (es) *	2000-08-14	2004-05-04	Corixa Corp	Composiciones y metodos para la terapia y diagnostico de malignidades asociadas con her-2/neu.
CU22979A1 (es) *	2000-12-08	2004-09-09	Centro Inmunologia Molecular	Combinación inmunoterapéutica para el tratamiento de tumores que sobre-expresan receptores con actividad quinasa en residuos de tirosina
EP1236740B1 (de) *	2001-02-28	2012-07-18	Bio Life Science Forschungs- und Entwicklungsges.m.b.H.	Vakzine gegen Krebserkrankungen, die mit dem HER-2/neu Onkogen assoziiert sind
CU23178A1 (es) *	2002-04-15	2006-09-22	Ct Ingenieria Genetica Biotech	INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA
FR2844514B1 (fr) *	2002-09-16	2007-10-19	Neovacs	Produit immunogene stable comprenant des heterocomplexes antigeniques, compositions les contenant et procede de preparation
EP1576966A4 (de) *	2002-12-27	2006-07-26	Shenzhen Tsinghua Yuanxing Bio	Verfahren zur herstellung eines impfstoffs, sowie anti-tumor-impfstoffe
WO2005007673A2 (en) *	2003-07-03	2005-01-27	Rush University Medical Center	Immunogenic peptides
US20060018911A1 (en) *	2004-01-12	2006-01-26	Dana Ault-Riche	Design of therapeutics and therapeutics

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5801005A (en) *	1993-03-17	1998-09-01	University Of Washington	Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US5550214A (en) *	1994-02-10	1996-08-27	Brigham And Women's Hospital	Isolated antigenic oncogene peptide fragments and uses

1999
- 1999-05-07 JP JP2000547851A patent/JP2002514573A/ja not_active Abandoned
- 1999-05-07 WO PCT/US1999/010065 patent/WO1999057981A1/en not_active Ceased
- 1999-05-07 EP EP99921790A patent/EP1075184A4/de not_active Withdrawn
- 1999-05-07 CA CA002330212A patent/CA2330212A1/en not_active Abandoned

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE PUBMED [online] NCBI; 5 May 2004 (2004-05-05), PARRY ET AL: "Identification of MUC1 proteolytic cleavage sites in vivo" *
See also references of WO9957981A1 *
SHAN DAMING ET AL: "Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies.", BLOOD, vol. 91, no. 5, 1 March 1998 (1998-03-01), pages 1644 - 1652, XP002182861, ISSN: 0006-4971 *
ZHANG SHENGLE ET AL: "Augmenting the immunogenicity of synthetic MUC1 peptide vaccines in mice.", CANCER RESEARCH, vol. 56, no. 14, 1996, pages 3315 - 3319, XP002097413, ISSN: 0008-5472 *

Also Published As

Publication number	Publication date
JP2002514573A (ja)	2002-05-21
CA2330212A1 (en)	1999-11-18
WO1999057981A1 (en)	1999-11-18
EP1075184A1 (de)	2001-02-14

Legal Events

Date	Code	Title	Description
2000-12-29	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2001-02-14	17P	Request for examination filed	Effective date: 20001204
2001-02-14	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): DE DK ES FR GB IT SE
2002-01-09	RIC1	Information provided on ipc code assigned before grant	Free format text: 7A 01N 37/18 A, 7A 61K 39/00 B, 7A 61K 39/385 B, 7A 61P 35/00 B, 7C 07K 14/705 -
2002-01-30	A4	Supplementary search report drawn up and despatched	Effective date: 20011218
2002-01-30	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): DE DK ES FR GB IT SE
2002-11-13	17Q	First examination report despatched	Effective date: 20020927
2005-08-24	GRAP	Despatch of communication of intention to grant a patent	Free format text: ORIGINAL CODE: EPIDOSNIGR1
2005-08-31	RTI1	Title (correction)	Free format text: METHOD FOR ACTIVE VACCINATION AGASINT CD20
2005-10-05	RTI1	Title (correction)	Free format text: METHOD FOR ACTIVE VACCINATION AGAINST CD20
2005-12-24	GRAS	Grant fee paid	Free format text: ORIGINAL CODE: EPIDOSNIGR3
2007-04-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2007-05-23	18D	Application deemed to be withdrawn	Effective date: 20061201

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