EP1139981A2 - Compositions et procedes d'utilisation associes - Google Patents

Compositions et procedes d'utilisation associes

Info

Publication number
EP1139981A2
EP1139981A2 EP99968903A EP99968903A EP1139981A2 EP 1139981 A2 EP1139981 A2 EP 1139981A2 EP 99968903 A EP99968903 A EP 99968903A EP 99968903 A EP99968903 A EP 99968903A EP 1139981 A2 EP1139981 A2 EP 1139981A2
Authority
EP
European Patent Office
Prior art keywords
total weight
composition
skin
barrier
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99968903A
Other languages
German (de)
English (en)
Other versions
EP1139981A4 (fr
Inventor
Andrew M. Homola
Ronald K. Dunton
Gary Pitts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Four Star Partners
Original Assignee
Four Star Partners
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Four Star Partners filed Critical Four Star Partners
Publication of EP1139981A2 publication Critical patent/EP1139981A2/fr
Publication of EP1139981A4 publication Critical patent/EP1139981A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/38—Percompounds, e.g. peracids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/10—Preparations containing skin colorants, e.g. pigments for eyes, e.g. eyeliner, mascara
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Definitions

  • the present invention also relates to compositions which provide
  • skin is meant to include not only the exterior integument or
  • compositions are often classified as being either medicated or non-medicated.
  • said mixture comprising:
  • transfer agent is present in said composition in an amount of at least
  • compositions comprising:
  • the present invention provides new compositions which form long-chain
  • compositions of the present invention may be applied to the skin either by
  • spray can brush, wipe, cotton puff, roll-on device, or other system or device
  • the materials used for covering the applicator-ends of the appliance may be any material used for covering the applicator-ends of the appliance.
  • non- woven, knitted, matted, felted, etc. material in which the materials of the
  • composition of the present invention (hereinafter MCPI) are held among or between
  • a single monolayer is
  • CAB cetyltrimethylammonium bromide
  • HDTAB hexadecyltrimethylammonium bromide
  • compositions of the present invention are generally liquid, semi-solid or
  • solid state materials which may be applied to skin surfaces by hand, by pouring, by
  • compositions of the present invention to be applied through the use of an atomizer, spray can, brush, wipe, cotton puff, roll-on device, or
  • compositions of the present invention as applied to the skin, provide a
  • the transfer agent component has dual functionality, being composed of
  • the barrier component is a hydrophobic, inert material (hereafter called
  • the "barrier” material such as a wax or polydimethylsiloxane which mixes with and
  • the thickness of the barrier stratum is typically between
  • compositions of the present invention may optionally include one or more
  • the present invention provides novel
  • compositions which comprise:
  • the present composition contains:
  • the present invention provides novel compositions
  • said mixture comprising:
  • transfer agent is present in said composition in an amount of at least
  • composition to skin said composition comprising:
  • the present composition contains:
  • the present invention provides a method for cleaning
  • composition comprising:
  • composition to skin said composition comprising:
  • the present invention provides a method for applying a
  • compositions described in the first or second embodiments and (B) 10 to 95 wt.%), based on the total weight of (A) and (B), of one or more
  • the present invention provides novel compositions
  • the present composition contains:
  • the present invention provides a method for applying a
  • said method comprising applying an effective amount of a
  • composition to skin said composition comprising:
  • the present composition comprises:
  • Useful transfer agent materials include various cetyl amine compounds,
  • various diamines including for example, Duomeens and Ethoduomeens
  • PEI polyethyleneimine
  • acids such as, for example, stearic acid, palmitic acid, oleic acid, etc.
  • Transfer agent materials that are capable of strong electrostatic
  • R represents a long (C 8 . 20 ) alkyl chain which may be substituted with one or more
  • R, R", and R'" each independently may be either a long (C 8 . 20 ) alkyl
  • alkyl groups which may be substituted with one or more hydroxy groups or aryl (C 6 . 10 )
  • X " represents an anion such as chloride or fluoride.
  • hydrophobic alkyl groups are linked to a cationic nitrogen atom.
  • the linkage is more complex as, for example, in RCONHCH 2 CH 2 CH 2 N(CH 3 ) 2 .
  • cationic transfer agents may contain more than one cationic nitrogen atom
  • CTAB cetyl trimethylammonium bromide
  • HDTAB hexadecyltrimethylammonium bromide
  • cetyl trimethylammonium halide bromide, chloride, fluoride
  • coconut alkyltrimethylammonium halide coconut alkyltrimethylammonium halide
  • N,N-C 8 . 20 -dialkyldimethylammonium halide and specifically compounds such as
  • heterocyclic ring Suitable compounds, for example, are as follows:
  • olefins olefins, paraffins, and aromatic hydrocarbons and include compounds with at least one
  • the polyethyleneimine is first
  • hydrogen halides such as hydrogen chloride or, preferentially, hydrogen fluoride.
  • reaction is typically performed with stearic or oleic acid chlorides in the presence of a
  • solvent containing metal fluoride preferentially silver fluoride, in such a manner that
  • polysaccharides such as dextran, starch or cellulose, for example, diethylaminoethyl
  • acrylamide and a cationic monomer are available commercially under the trade name
  • Such polymers are FLOC AID 305 and RETEN 220. Similarly, particularly examples of such polymers are FLOC AID 305 and RETEN 220. Similarly, particularly examples of such polymers are FLOC AID 305 and RETEN 220. Similarly, particularly examples of such polymers are FLOC AID 305 and RETEN 220. Similarly, particularly examples of such polymers are FLOC AID 305 and RETEN 220. Similarly, particularly examples of such polymers are FLOC AID 305 and RETEN 220. Similarly, FLOC AID 305 and RETEN 220. .
  • acrylamide-based polyelectrolytes as sold by Allied Colloids under the
  • PERCOL trade name PERCOL.
  • Suitable materials are the cationic guar
  • a further preferred group of compounds which comprises a class of water-
  • insoluble polymers having nitrogen atoms in their molecules, are quaternary
  • the transfer agent a cationic surfactant
  • the nitrogen atoms are quatemized by formation of a salt with a C 8 . 20 fatty acid,
  • polyacrylamides polyvinylpyridines, or polyamines, e.g., poly(ethyleneimine), in
  • weight average molecular weight 600 to 60,000, preferably 600 to
  • the transfer agent is a polymer which contains a
  • polymeric cationic surfactants examples include
  • polyacrylamides polyvinylpyridines or polyamines, e.g., poly(ethyleneimine), in which from 5 to 95 mole%>, preferably from 40 to 60 mole %, of the nitrogen atoms
  • the polymeric cationic surfactant will have
  • the transfer agent is a C 8 _ 20 -alkylamine
  • citric acid such as cetylamine citrate
  • lecithin includes compounds of the formulae
  • R 1 , R 2 , R 3 , and R 4 are each, independently of each other, a C 12 _ 22 saturated or
  • unsaturated alkanoyl group such as stearoyl, palmitoyl, oleoyl, palmitoleoyl,
  • the lecithin may but does not necessarily function as both
  • the transfer agent and, according to the known art, as a skin care active agent.
  • Adogen 185 CAS 686-10-26-4 Witco
  • Adogen 340 (flaked) Trihydrogenated tallow amines Witco
  • Adogen 570 S CAS 61791-55-7 Witco
  • Adogen 422 Behenyltrimethyl Ammonium chloride
  • physiologic pH i.e., those which are positively charged when
  • any of several hydrophobic barrier materials may be selected to perform this
  • polymeric barrier appears to endure in place and function indefinitely or until it is
  • compositions of the present inventions are sprayed, brushed, or
  • barrier rubbed on the skin, even wet skin or skin immersed in water.
  • barrier
  • materials are amorphous materials which shear or cleave easily so that materials
  • Suitable barrier materials are disclosed in U.S. Patent No. 5,665,333 and U.S.
  • barrier forming materials typically they are long chain hydrocarbons, especially
  • wax-like materials belong to two basic categories:
  • lanolin spermaceti, carnauba wax, petroleum waxes including paraffin waxes,
  • microcrystalline petrolatum and microcrystalline wax are microcrystalline petrolatum and microcrystalline wax.
  • Synthetic materials including ethylenic polymers such as polyethylene
  • silicone-based polymers such as silicone-based polymers
  • polymethylalkylsiloxanes polydimethylsiloxanes, poly(perfluoroalkylmethyl)
  • siloxanes poly(methyl-3,3,3-trifluoropropyl siloxanes) and various aromatic (phenyl)
  • fluorine including, among others: polytetrafluoroethylene (PTFE);
  • FEP fluorinated polyethylene-propylene
  • PFA perfluoroalkoxy
  • PVDF polyvinylidene fluoride
  • PVF polyvinylfluoride
  • composition of the present invention may be incorporated into the composition of the present invention
  • the active skin care agents by sweating, washing, swimming, or incidental contact, or
  • These skin care agents may be blended into the barrier material so that, as the barrier material is sheared, cleaved, disturbed, eroded, abraded,
  • Such skin care active agents include, but are not limited to,
  • Methylprednisone Acetate Methylprednisone Sodium Succinate
  • fragrances to mask any color or odor of the other ingredients or to provide a more
  • compositions preferably 0.1 to 1.0 wt.%, based on the total weight of the composition.
  • compositions may also include manufacturing aids, modifiers and
  • thickeners diluents, solvents, emulsifiers, stabilizers, and ingredients which enhance
  • surfactant to the present skin care composition will decrease the activity of the transfer
  • the present skin care compositions preferably contain at least 0.25 wt.%
  • the present skin care compositions contain at least 0.25 wt.%> of a transfer
  • present skin care compositions preferably contain at least 1 wt.% of transfer agent above and beyond the amount of transfer agent which is neutralized by any
  • anionic reagent also present in the composition.
  • anionic reagent also present in the composition.
  • anionic reagent also present in the composition.
  • anionic reagent from the cationic transfer agent.
  • anionic reagents contain more than one anionic
  • anionic neutralizing groups contained in the anionic reagent equivalents of anionic neutralizing groups contained in the anionic reagent.
  • soluble compounds with anionic groups which may, for example,
  • anionic reagents include anionic
  • Anionic surfactants are disclosed in McCutcheon's: Volume 1 : Emulsifiers and Detergents, North American and International Editions, Pub. by
  • anionic surfactants include: sulfates,
  • compositions may also be prepared by
  • conditions include but are not limited to acne, athlete's foot, jock itch, ringworm,
  • kidney diseases including kidney diseases, atherscleroses, etc. listed in Dorland's Illustrated Medical Dictionary, Stedman's Medical Dictionary,
  • compositions and methods are useful to minimize the appearance
  • composition to the skin or tissues in contact with the implant or on
  • Diaper Rash (the present compositions may be applied to the affected area or
  • Anti-Drying the present compositions may be used to form a protective

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cosmetics (AREA)
  • Adhesives Or Adhesive Processes (AREA)

Abstract

L'invention concerne des compositions contenant au moins un agent de transfert et au moins un matériau barrière qui forment, lors de leur application sur un substrat, même un substrat mouillé ou immergé dans l'eau, une barrière protectrice adhérente. Les compositions peuvent être modifiées de façon à fournir une viscosité adéquate et d'autres caractéristiques et peuvent servir d'excipient pour des principes actifs.
EP99968903A 1998-12-24 1999-12-23 Compositions et procedes d'utilisation associes Withdrawn EP1139981A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11395098P 1998-12-24 1998-12-24
US113950P 1998-12-24
US11728399P 1999-01-26 1999-01-26
US117283P 1999-01-26
PCT/US1999/030003 WO2000038617A2 (fr) 1998-12-24 1999-12-23 Compositions et procedes d'utilisation associes

Publications (2)

Publication Number Publication Date
EP1139981A2 true EP1139981A2 (fr) 2001-10-10
EP1139981A4 EP1139981A4 (fr) 2002-04-17

Family

ID=26811670

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99968903A Withdrawn EP1139981A4 (fr) 1998-12-24 1999-12-23 Compositions et procedes d'utilisation associes

Country Status (4)

Country Link
EP (1) EP1139981A4 (fr)
AU (1) AU2710300A (fr)
CA (1) CA2356840A1 (fr)
WO (1) WO2000038617A2 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11058793B2 (en) 2011-05-16 2021-07-13 Avery Dennison Corporation Adhesive containing microparticles
US11213432B2 (en) 2013-03-15 2022-01-04 Avery Dennison Corporation Transparent cover dressing application system and inclusion of label strip
US11318223B2 (en) 2013-02-07 2022-05-03 Avery Dennison Corporation Antimicrobial adhesives having improved properties
US11337940B2 (en) 2014-06-05 2022-05-24 Avery Dennison Corporation Articles with active agent concentrated at the substrate contacting surface and related methods

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070212314A1 (en) * 2004-09-07 2007-09-13 Dow Corning Corporation Silicone Adhesive Formulation Containing An Antiperspirant
FR2876907B1 (fr) * 2004-10-27 2007-02-23 Serge Bernstein Solutions aqueuses pour la reduction de tissus graisseux
WO2006093124A1 (fr) * 2005-02-28 2006-09-08 Manac Inc. Piège à radicaux libres contenant un dérivé de semicarbazide
AR062835A1 (es) * 2007-08-29 2008-12-10 Walter Montagni Una composicon estimulante selectiva de la cicatrizacion su preparcion y aplicacion
EP3060310A1 (fr) * 2013-10-23 2016-08-31 Unilever PLC Composition antitranspirante
CA3012227C (fr) 2015-01-23 2023-05-23 Biocidium Biopharmaceuticals Inc. Compositions anti-bacteriennes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470292A (en) * 1965-06-01 1969-09-30 Colgate Palmolive Co Film-forming composition containing a phosphatide and a siloxane
SU833240A1 (ru) * 1979-03-12 1981-05-30 Московский Ордена Ленина И Орденатрудового Красного Знамени Химико- Технологический Институт Им.Д.И.Менделеева Защитный крем дл рук
EP0408174A1 (fr) * 1989-07-12 1991-01-16 Warner-Lambert Company Composition antiseptique contenant des composés de hexahydro-5-pyrimidinamine
DE4341794C1 (de) * 1993-12-08 1995-01-19 Henkel Kgaa Kosmetische und/oder pharmazeutische Zubereitungen mit verbessertem Hautgefühl
US5425938A (en) * 1994-01-28 1995-06-20 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Polyamino salts of alpha-hydroxyacids, alpha-ketoacids and related compounds
US5665333A (en) * 1995-01-17 1997-09-09 Homola; Andrew M. Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth
GB2329585A (en) * 1996-05-17 1999-03-31 Secr Defence Brit A barrier cream comprising hexamethylenetetramine or derivative thereo
US5961958A (en) * 1996-07-16 1999-10-05 Four Star Partners Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth
SE9604610D0 (sv) * 1996-12-16 1996-12-16 Noviscens Ab Medical composition

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11058793B2 (en) 2011-05-16 2021-07-13 Avery Dennison Corporation Adhesive containing microparticles
US11707549B2 (en) 2011-05-16 2023-07-25 Avery Dennison Corporation Adhesive containing microparticles
US12036335B2 (en) 2011-05-16 2024-07-16 Avery Dennison Corporation Adhesive containing microparticles
US11318223B2 (en) 2013-02-07 2022-05-03 Avery Dennison Corporation Antimicrobial adhesives having improved properties
US11213432B2 (en) 2013-03-15 2022-01-04 Avery Dennison Corporation Transparent cover dressing application system and inclusion of label strip
US11337940B2 (en) 2014-06-05 2022-05-24 Avery Dennison Corporation Articles with active agent concentrated at the substrate contacting surface and related methods
US12109180B2 (en) 2014-06-05 2024-10-08 Avery Dennison Corporation Articles with active agent concentrated at the substrate contacting surface and related methods

Also Published As

Publication number Publication date
WO2000038617A3 (fr) 2000-09-21
AU2710300A (en) 2000-07-31
CA2356840A1 (fr) 2000-07-06
EP1139981A4 (fr) 2002-04-17
WO2000038617A2 (fr) 2000-07-06

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