EP1182143A2 - Verschluss für Phiolen - Google Patents

Verschluss für Phiolen Download PDF

Info

Publication number
EP1182143A2
EP1182143A2 EP01120237A EP01120237A EP1182143A2 EP 1182143 A2 EP1182143 A2 EP 1182143A2 EP 01120237 A EP01120237 A EP 01120237A EP 01120237 A EP01120237 A EP 01120237A EP 1182143 A2 EP1182143 A2 EP 1182143A2
Authority
EP
European Patent Office
Prior art keywords
vial
closure
diameter
opening
seal portion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01120237A
Other languages
English (en)
French (fr)
Other versions
EP1182143A3 (de
Inventor
Morihiro Sudo
Kouichi Asai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daikyo Seiko Ltd
Original Assignee
Daikyo Seiko Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daikyo Seiko Ltd filed Critical Daikyo Seiko Ltd
Publication of EP1182143A2 publication Critical patent/EP1182143A2/de
Publication of EP1182143A3 publication Critical patent/EP1182143A3/de
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D39/00—Closures arranged within necks or pouring openings or in discharge apertures, e.g. stoppers
    • B65D39/0005—Closures arranged within necks or pouring openings or in discharge apertures, e.g. stoppers made in one piece
    • B65D39/0023—Plastic cap-shaped hollow plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D39/00—Closures arranged within necks or pouring openings or in discharge apertures, e.g. stoppers
    • B65D39/16—Closures arranged within necks or pouring openings or in discharge apertures, e.g. stoppers with handles or other special means facilitating manual actuation

Definitions

  • the present invention relates to a closure to close an opening of a medical vial (container) which holds therein liquid medicament.
  • a closure (rubber closure) for a vial is made of a rubber material such as butyl rubber and has a cylindrical stem portion which can be inserted in the opening of the vial and a head portion which has a diameter larger than that of the stem portion and which is located on the outside of the opening of the vial.
  • the stem portion of a conventional closure is provided with a close contact portion (barrel portion) having a uniform diameter which is brought into close contact with the opening of the vial and which is located adjacent to the head portion, or is provided on its barrel portion with a sealing annular projection which is in close contact with the opening of the vial.
  • a desired position of such a sealing annular projection is disclosed, for example, in Japanese Unexamined Utility Model No. Sho-61-2233.
  • the sealing annular projection When the stem portion is fitted in the opening of the vial, the sealing annular projection is compressed more than the remaining portion of the barrel portion, and hence, it has been considered that the sealing annular projection contributes to preventing the stem portion from slipping off from the opening of the vial.
  • a CS vial Fluji Glass CO., Ltd.
  • the sealing annular projection engages with the small diameter portion, so that the slip-off prevention effect can be enhanced.
  • the sealing annular projection which is compressed more than the remaining portion sometimes produces a force in a direction opposite to the direction of insertion to thereby disengage the closure from the vial. Because of this phenomenon, the sealing annular projection has also been regarded as having an opposite effect to that of slip-off prevention.
  • a closure for a vial including a head portion, and a stem portion which projects from a lower surface of the head portion, the stem portion being inserted in an opening of a vial; wherein the stem portion is provided with a small diameter portion and a seal portion, in that order from the lower surface the head portion, the diameter of the small diameter portion being smaller than the diameter of the seal portion.
  • the entirety of the small diameter portion and the seal portion are substantially uniformly fitted in the opening of the vial.
  • the following condition is satisfied: 0.80D ⁇ d ⁇ 0.98D; wherein 'd' designates the diameter of the small diameter portion, and 'D' designates the diameter of the seal portion.
  • the stem portion is further provided with a leg portion connected to the seal portion, the leg portion being provided with at least one radial opening and a plurality of half-insertion projections formed on the outer peripheral surface of the seal portion, the diameter of the seal portion being smaller than the diameter of a circumscribed circle of the half-insertion projections.
  • the following condition is satisfied: S/5 ⁇ j ⁇ S/20; wherein ' j ' designates the axial length of the small diameter portion, and 'S' designates the axial length of the seal portion.
  • a closure 10 for a vial 20 is composed of a head portion (top plate) 11 in the form of a circular disc, and a cylindrical stem portion 12, which has a diameter smaller than that of the head portion 11 and which projects from the lower surface of the head portion 11.
  • the stem portion 12 is fitted in an opening (bottle neck) 21 of the vial (container for holding liquid medicament) 20.
  • the head portion 11 is in contact with an end face 22 of the opening 21.
  • the stem portion 12 is provided with a seal portion 13 adjacent to the head portion 11 and a leg portion 14 connected to the seal portion 13.
  • the seal portion 13 is provided on its end adjacent to the head portion 11, with a small diameter portion 15 having a smaller diameter.
  • the seal portion 13 has a uniform diameter D which is slightly greater than the uniform inner diameter x of the opening 21 of the vial 20, so that when the stem portion is inserted in the opening 21, the seal portion 13 is uniformly compressed to establish a press fit therebetween.
  • the seal portion 13 can be provided with a slightly tapered peripheral surface.
  • S is the axial length of the seal portion 13.
  • the diameter of the head portion 11 is in the range of 10mm through 30 mm and the overall length of the stem portion 12 is in the range of 5mm through 30 mm.
  • the leg portion 14 of the stem portion 12 is provided with a radial opening 16 through which cleaning liquid can easily enter the stem portion 12.
  • the leg portion 14 is provided on its outer peripheral surface with a plurality of half-insertion projections 17 (three projections in the illustrated in Figure 2) at an equal angular distance.
  • the projections 17 first engage with the inner peripheral surface of the opening 21 to provisionally hold the closure 10 while keeping the posture thereof before the closure 10 is completely inserted in the vial 20.
  • the outer diameter D of the seal portion 13 is smaller than a diameter t of a circumscribed circle to the projections 17. If the diameter D were substantially identical to the diameter t, it would be impossible to completely insert the closure 10 in the vial 20. If the diameter t of the circumscribed circle is larger than the outer diameter D, the stem portion can be easily deformed due to the presence of the opening 16, so that the closure 10 can be half-inserted easily.
  • the opening 16 and the projections 17 can be appropriately increased in number.
  • the closure 10 is forced (press-fitted) into the opening 21 of the vial 20, after the vial 20 is filled with liquid medicament.
  • the leg portion 14 of the stem portion 12 is elastically deformed and is inserted in the opening 21. Consequently, the projections 17, provided on the outer peripheral surface of the stem portion 14, are frictionally engaged with the inner surface of the opening 21 of the vial 20 to establish a provisional holding (half-insertion state).
  • the seal portion 13 is pressed onto and brought into uniform surface contact with the inner peripheral surface of the opening 21 of the vial 20, so that the lower surface (under surface) of the head portion 11 comes into contact with the end face 22 of the opening 21.
  • the stem portion of the closure for a vial is provided, on the portion thereof adjacent to the head portion, with a seal portion that is entirely fitted in and brought into close surface-contact with the inner surface of the opening of the vial, and the seal portion is provided on an end thereof adjacent to the head portion with a small diameter portion whose diameter is smaller than the diameter of the main body of the seal portion.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP01120237A 2000-08-25 2001-08-23 Verschluss für Phiolen Withdrawn EP1182143A3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000254854A JP2002065809A (ja) 2000-08-25 2000-08-25 バイアル用栓体
JP2000254854 2000-08-25

Publications (2)

Publication Number Publication Date
EP1182143A2 true EP1182143A2 (de) 2002-02-27
EP1182143A3 EP1182143A3 (de) 2002-05-08

Family

ID=18743731

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01120237A Withdrawn EP1182143A3 (de) 2000-08-25 2001-08-23 Verschluss für Phiolen

Country Status (4)

Country Link
US (1) US20020023893A1 (de)
EP (1) EP1182143A3 (de)
JP (1) JP2002065809A (de)
CA (1) CA2354874A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103211702A (zh) * 2013-04-17 2013-07-24 常熟市康宝医疗器械厂 医用喂食、冲洗袋的加液口结构

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7243689B2 (en) 2000-02-11 2007-07-17 Medical Instill Technologies, Inc. Device with needle penetrable and laser resealable portion and related method
US7100646B2 (en) 2000-02-11 2006-09-05 Medical Instill Technologies, Inc. Sealed containers and methods of making and filling same
WO2003033363A1 (en) * 2001-10-16 2003-04-24 Medical Instill Technologies, Inc. Dispenser with sealed chamber and one-way valve for providing metered amounts of substances
US7798185B2 (en) 2005-08-01 2010-09-21 Medical Instill Technologies, Inc. Dispenser and method for storing and dispensing sterile food product
HU230187B1 (hu) * 2001-12-10 2015-09-28 Alcoa Deutschland Gmbh Verpackungswerke Tartály, különösen italos palack
EP2433871A3 (de) 2002-06-19 2012-07-11 Medical Instill Technologies, Inc. Zum sterilen Füllen bestimmte Maschine mit Nadelfüllstation in einer Elektronenstrahlkammer
USD485365S1 (en) 2002-09-03 2004-01-13 Medical Instill Technologies, Inc. Vial
USD561908S1 (en) 2002-09-03 2008-02-12 Medical Instill Technologies, Inc. Vial
USD522663S1 (en) 2002-09-03 2006-06-06 Medical Instill Technologies, Inc. Vial
USD533670S1 (en) 2002-09-03 2006-12-12 Medical Instill Technologies, Inc. Vial
US7188748B2 (en) * 2003-03-04 2007-03-13 Diaperoos, Llc Vacuum-packed diaper vending machine
WO2004096113A2 (en) * 2003-04-28 2004-11-11 Medical Instill Technologies, Inc. Container with valve assembly for filling and dispensing substances, and apparatus and method for filling
USD527463S1 (en) 2004-01-27 2006-08-29 Medical Instill Technologies, Inc. Vial
US7934614B2 (en) * 2006-06-07 2011-05-03 J. G. Finneran Associates, Inc. Two-piece seal vial assembly
HUE026463T2 (en) * 2007-10-18 2016-05-30 Daikyo Seiko Ltd rubber Stopper
IT201700047199A1 (it) * 2017-05-02 2018-11-02 Goglio Spa Tappo a pressione e contenitore ermetico dotato di tale tappo a pressione
JP2022086498A (ja) * 2020-11-30 2022-06-09 株式会社エンプラス 容器
CN113184356A (zh) * 2021-03-16 2021-07-30 李亚峰 一种密封性好的炎症生化检测试剂盒
CN114506568A (zh) * 2022-02-23 2022-05-17 深圳市爱善科技有限公司 一种化妆瓶的内塞结构

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS612233U (ja) 1984-06-11 1986-01-08 藤沢薬品工業株式会社 バイアル用栓体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3136440A (en) * 1963-06-25 1964-06-09 Becton Dickinson Co Self sealing pierceable stopper for sealed containers
US4230231A (en) * 1979-04-16 1980-10-28 Coulter Electronics, Inc. Closure cap
JPS5858057A (ja) * 1981-10-02 1983-04-06 テルモ株式会社 医療容器用栓体
DE8716988U1 (de) * 1987-12-24 1989-04-20 Helvoet Pharma N.V., Alken Gefriertrocknungs-Stopfen

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS612233U (ja) 1984-06-11 1986-01-08 藤沢薬品工業株式会社 バイアル用栓体

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103211702A (zh) * 2013-04-17 2013-07-24 常熟市康宝医疗器械厂 医用喂食、冲洗袋的加液口结构

Also Published As

Publication number Publication date
JP2002065809A (ja) 2002-03-05
US20020023893A1 (en) 2002-02-28
EP1182143A3 (de) 2002-05-08
CA2354874A1 (en) 2002-02-25

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