EP1192009A4 - Verfahren zur erzeugung eines aerosols - Google Patents

Verfahren zur erzeugung eines aerosols

Info

Publication number
EP1192009A4
EP1192009A4 EP00938249A EP00938249A EP1192009A4 EP 1192009 A4 EP1192009 A4 EP 1192009A4 EP 00938249 A EP00938249 A EP 00938249A EP 00938249 A EP00938249 A EP 00938249A EP 1192009 A4 EP1192009 A4 EP 1192009A4
Authority
EP
European Patent Office
Prior art keywords
producing aerosol
aerosol
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP00938249A
Other languages
English (en)
French (fr)
Other versions
EP1192009A1 (de
EP1192009B1 (de
Inventor
Joan Rosell
Alfonso Ganan-Calvo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Sevilla
Aradigm Corp
Original Assignee
Universidad de Sevilla
Aradigm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Sevilla, Aradigm Corp filed Critical Universidad de Sevilla
Publication of EP1192009A1 publication Critical patent/EP1192009A1/de
Publication of EP1192009A4 publication Critical patent/EP1192009A4/de
Application granted granted Critical
Publication of EP1192009B1 publication Critical patent/EP1192009B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
    • B05B7/0416—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid
    • B05B7/0441—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with one inner conduit of liquid surrounded by an external conduit of gas upstream the mixing chamber
    • B05B7/0475—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with one inner conduit of liquid surrounded by an external conduit of gas upstream the mixing chamber with means for deflecting the peripheral gas flow towards the central liquid flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
    • B05B7/0416—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid
    • B05B7/0483—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with gas and liquid jets intersecting in the mixing chamber
EP00938249.0A 1999-06-11 2000-06-09 Verfahren zur erzeugung eines aerosols Expired - Lifetime EP1192009B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13869899P 1999-06-11 1999-06-11
US138698P 1999-06-11
PCT/US2000/015931 WO2000076673A1 (en) 1999-06-11 2000-06-09 Method for producing an aerosol

Publications (3)

Publication Number Publication Date
EP1192009A1 EP1192009A1 (de) 2002-04-03
EP1192009A4 true EP1192009A4 (de) 2006-10-18
EP1192009B1 EP1192009B1 (de) 2013-05-01

Family

ID=22483216

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00938249.0A Expired - Lifetime EP1192009B1 (de) 1999-06-11 2000-06-09 Verfahren zur erzeugung eines aerosols

Country Status (6)

Country Link
EP (1) EP1192009B1 (de)
JP (1) JP2003501257A (de)
AU (1) AU767486B2 (de)
CA (1) CA2374232C (de)
ES (1) ES2424713T4 (de)
WO (1) WO2000076673A1 (de)

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US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
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US7498019B2 (en) 2001-05-24 2009-03-03 Alexza Pharmaceuticals, Inc. Delivery of compounds for the treatment of headache through an inhalation route
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
WO2002094218A2 (en) 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US6759029B2 (en) 2001-05-24 2004-07-06 Alexza Molecular Delivery Corporation Delivery of rizatriptan and zolmitriptan through an inhalation route
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US6805853B2 (en) 2001-11-09 2004-10-19 Alexza Molecular Delivery Corporation Delivery of diazepam through an inhalation route
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
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CA2460343A1 (en) 2001-11-21 2003-07-17 Alexza Molecular Delivery Corporation Delivery of caffeine through an inhalation route
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
JP2006507921A (ja) * 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
US7550133B2 (en) 2002-11-26 2009-06-23 Alexza Pharmaceuticals, Inc. Respiratory drug condensation aerosols and methods of making and using them
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US20040234699A1 (en) 2003-05-21 2004-11-25 Alexza Molecular Delivery Corporation Methods of controlling uniformity of substrate temperature and self-contained heating unit and drug-supply unit employing same
US20040235308A1 (en) 2003-05-22 2004-11-25 Dainippon Screen Mfg. Co., Ltd. Substrate treatment method and sustrate treatment apparatus
CN104069784B (zh) 2003-08-27 2017-01-11 哈佛大学 流体物种的电子控制
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
US9477233B2 (en) 2004-07-02 2016-10-25 The University Of Chicago Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets
US7655470B2 (en) 2004-10-29 2010-02-02 University Of Chicago Method for manipulating a plurality of plugs and performing reactions therein in microfluidic systems
EP2246086A3 (de) 2004-08-12 2012-11-21 Alexza Pharmaceuticals, Inc. Aerosolverabreichungsvorrichtung mit Schlag gezündete Heizeinheit
ES2264608B2 (es) * 2004-09-30 2007-08-16 Universidad De Sevilla Dispositivo y procedimiento para la atomizacion neumatica de liquidos mediante flujo implosivo de gas.
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
ES2265270B1 (es) * 2005-04-18 2008-01-01 Universidad De Sevilla Procedimiento y dispositivo para micro-mezclado de fluidos mediante celula de reflujo.
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US9039273B2 (en) 2005-03-04 2015-05-26 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
EP2363205A3 (de) 2006-01-11 2014-06-04 Raindance Technologies, Inc. Mikrofluidische Vorrichtungen Und Verfahren Zur Verwendung Bei Der Bildung Und Kontrolle Von Nanoreaktoren
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP2530168B1 (de) 2006-05-11 2015-09-16 Raindance Technologies, Inc. Mikrofluidische Vorrichtungen
EP2077912B1 (de) 2006-08-07 2019-03-27 The President and Fellows of Harvard College Fluorkohlenstoffemulsionsstabilisierende tenside
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
EP2121088B1 (de) 2007-03-09 2016-07-13 Alexza Pharmaceuticals, Inc. Erhitzungseinheit zur verwendung in einer arzneimittelabgabevorrichtung
EP2136786B8 (de) 2007-03-28 2012-11-14 President and Fellows of Harvard College Vorrichtung zur Formung von Tröpfchen
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
WO2009129547A1 (en) 2008-04-18 2009-10-22 The Board Of Trustees Of The University Of Alabama Meso-scaled combustion system
WO2010009365A1 (en) 2008-07-18 2010-01-21 Raindance Technologies, Inc. Droplet libraries
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
US20100176063A1 (en) * 2009-01-12 2010-07-15 Yuri Kokotov Method for coalescence induced liquid-liquid separations and apparatus thereof
US8528589B2 (en) 2009-03-23 2013-09-10 Raindance Technologies, Inc. Manipulation of microfluidic droplets
WO2011028764A2 (en) 2009-09-02 2011-03-10 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
US10520500B2 (en) 2009-10-09 2019-12-31 Abdeslam El Harrak Labelled silica-based nanomaterial with enhanced properties and uses thereof
EP2517025B1 (de) 2009-12-23 2019-11-27 Bio-Rad Laboratories, Inc. Verfahren zur reduzierung des austauschs von molekülen zwischen tröpfchen
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
JP5934657B2 (ja) 2010-02-12 2016-06-15 レインダンス テクノロジーズ, インコーポレイテッド デジタル検体分析
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
WO2011150368A1 (en) 2010-05-28 2011-12-01 Arizona Board Of Regents Acting For And On Behalf Of Arziona State University Apparatus and methods for a gas dynamic virtual nozzle
US20120048963A1 (en) 2010-08-26 2012-03-01 Alexza Pharmaceuticals, Inc. Heat Units Using a Solid Fuel Capable of Undergoing an Exothermic Metal Oxidation-Reduction Reaction Propagated without an Igniter
WO2012045012A2 (en) 2010-09-30 2012-04-05 Raindance Technologies, Inc. Sandwich assays in droplets
EP3859011A1 (de) 2011-02-11 2021-08-04 Bio-Rad Laboratories, Inc. Verfahren zur bildung gemischter tröpfchen
EP2675819B1 (de) 2011-02-18 2020-04-08 Bio-Rad Laboratories, Inc. Zusammensetzungen und verfahren für molekulare etikettierung
JP6122843B2 (ja) 2011-05-23 2017-04-26 プレジデント アンド フェローズ オブ ハーバード カレッジ 多重エマルジョンを含むエマルジョンの制御
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
DE202012013668U1 (de) 2011-06-02 2019-04-18 Raindance Technologies, Inc. Enzymquantifizierung
US20140220350A1 (en) 2011-07-06 2014-08-07 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
EP2777818A1 (de) 2013-03-15 2014-09-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren und Vorrichtung zur Herstellung eines intermittierenden Flüssigkeitsstrahls
EP2991768B1 (de) 2013-04-30 2018-11-21 Arizona Board of Regents on behalf of Arizona State University Vorrichtung und verfahren für kubische lipidphaseninjektion für membranproteinuntersuchungen
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
US11193176B2 (en) 2013-12-31 2021-12-07 Bio-Rad Laboratories, Inc. Method for detecting and quantifying latent retroviral RNA species
HRP20240104T1 (hr) 2015-03-11 2024-05-10 Alexza Pharmaceuticals, Inc. Uporaba antistatičkih materijala u dišnim putevima za proces kondenzacije toplinskog aerosola
CN108348933B (zh) 2015-08-28 2022-01-28 明尼苏达州大学董事会 喷嘴和混合流体流的方法
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
ES2663217B1 (es) * 2016-10-10 2019-02-07 Ingeniatrics Tecnologias S L Aparato y método para mezclar al menos dos líquidos
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device
WO2019241488A1 (en) 2018-06-14 2019-12-19 Regents Of The University Of Minnesota Counterflow mixer and atomizer
US10369579B1 (en) 2018-09-04 2019-08-06 Zyxogen, Llc Multi-orifice nozzle for droplet atomization
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Citations (1)

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Publication number Priority date Publication date Assignee Title
EP0899017A1 (de) * 1996-05-13 1999-03-03 Universidad De Sevilla, Vicerrectorado De Investigacion Verfahren zur zerstäubung von flüssigkeiten

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JPH05138080A (ja) * 1991-11-25 1993-06-01 Matsushita Electric Ind Co Ltd 霧化装置
US5868322A (en) * 1996-01-31 1999-02-09 Hewlett-Packard Company Apparatus for forming liquid droplets having a mechanically fixed inner microtube
US5884846A (en) * 1996-09-19 1999-03-23 Tan; Hsiaoming Sherman Pneumatic concentric nebulizer with adjustable and capillaries
EP1037858A1 (de) 1997-12-17 2000-09-27 Universidad de Sevilla Vorrichtung und verfahren zur herstellung von kugelförmigen teilchen einheitlicher grösse

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0899017A1 (de) * 1996-05-13 1999-03-03 Universidad De Sevilla, Vicerrectorado De Investigacion Verfahren zur zerstäubung von flüssigkeiten

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0076673A1 *

Also Published As

Publication number Publication date
JP2003501257A (ja) 2003-01-14
WO2000076673A1 (en) 2000-12-21
CA2374232A1 (en) 2000-12-21
AU5331800A (en) 2001-01-02
CA2374232C (en) 2013-08-20
EP1192009A1 (de) 2002-04-03
EP1192009B1 (de) 2013-05-01
ES2424713T3 (es) 2013-10-07
AU767486B2 (en) 2003-11-13
ES2424713T4 (es) 2014-01-23

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