EP1425383A4 - Stabilisation de cellules et de specimens biologiques pour l'analyse - Google Patents
Stabilisation de cellules et de specimens biologiques pour l'analyseInfo
- Publication number
- EP1425383A4 EP1425383A4 EP02768676A EP02768676A EP1425383A4 EP 1425383 A4 EP1425383 A4 EP 1425383A4 EP 02768676 A EP02768676 A EP 02768676A EP 02768676 A EP02768676 A EP 02768676A EP 1425383 A4 EP1425383 A4 EP 1425383A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- analysis
- damage
- vitro
- methods
- clusters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/549—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic with antigen or antibody entrapped within the carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31415101P | 2001-08-23 | 2001-08-23 | |
| US314151P | 2001-08-23 | ||
| US36962802P | 2002-04-03 | 2002-04-03 | |
| US369628P | 2002-04-03 | ||
| PCT/US2002/026867 WO2003018757A2 (fr) | 2001-08-23 | 2002-08-23 | Stabilisation de cellules et de specimens biologiques pour l'analyse |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1425383A2 EP1425383A2 (fr) | 2004-06-09 |
| EP1425383A4 true EP1425383A4 (fr) | 2005-11-09 |
Family
ID=26979228
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP02761478A Expired - Lifetime EP1425294B2 (fr) | 2001-08-23 | 2002-08-23 | Analyse de cellules tumorales en circulation, de fragments et de debris associes |
| EP02768676A Withdrawn EP1425383A4 (fr) | 2001-08-23 | 2002-08-23 | Stabilisation de cellules et de specimens biologiques pour l'analyse |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP02761478A Expired - Lifetime EP1425294B2 (fr) | 2001-08-23 | 2002-08-23 | Analyse de cellules tumorales en circulation, de fragments et de debris associes |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP1425294B2 (fr) |
| JP (3) | JP2005501236A (fr) |
| KR (2) | KR20040030984A (fr) |
| CN (2) | CN1596265A (fr) |
| AT (1) | ATE401574T1 (fr) |
| AU (2) | AU2008288601B2 (fr) |
| BR (2) | BR0212124A (fr) |
| CA (2) | CA2457891C (fr) |
| DE (1) | DE60227678D1 (fr) |
| IL (2) | IL160209A0 (fr) |
| WO (2) | WO2003019141A2 (fr) |
Families Citing this family (113)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1425294B2 (fr) * | 2001-08-23 | 2012-12-12 | Veridex, LLC | Analyse de cellules tumorales en circulation, de fragments et de debris associes |
| US7863012B2 (en) | 2004-02-17 | 2011-01-04 | Veridex, Llc | Analysis of circulating tumor cells, fragments, and debris |
| US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| AU2003234382B2 (en) | 2002-05-13 | 2010-07-08 | Becton, Dickinson And Company | Protease inhibitor sample collection system |
| CA2500392C (fr) | 2002-09-27 | 2012-11-27 | The General Hospital Corporation | Dispositif microfluidique pour la separation de cellules et utilisations de ce dispositif |
| EP1413874A1 (fr) | 2002-10-16 | 2004-04-28 | Streck Laboratories, Inc. | Méthode et appareil pour collecter et préserver des cellules pour l'analyse |
| EP1597353B1 (fr) | 2003-02-27 | 2010-11-24 | Veridex, LLC | Cellules tumorales circulantes (ctc): evaluation precoce du temps d'evolution, de la survie et de la reaction aux therapies des patients cancereux metastasiques |
| CA2539108A1 (fr) * | 2003-09-18 | 2005-03-31 | Immunivest Corporation | Systeme d'analyse et de preparation d'echantillon programmable independamment de l'operateur |
| CA2600225C (fr) * | 2005-03-14 | 2016-06-28 | Immunivest Corporation | Methode de prediction de survie sans progression et de survie globale, a chaque instant du suivi, au cours du traitement de patientes atteintes du cancer du sein metastatique, utilisant des cellules tumorales circulantes |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| ES2511218T5 (es) | 2005-06-20 | 2017-12-07 | Advanced Cell Diagnostics, Inc. | Kits y productos para detección de ácidos nucleicos en células individuales y para identificación de células raras en grandes poblaciones de células heterogéneas |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US8337755B2 (en) | 2006-03-13 | 2012-12-25 | Veridex, Llc | Operator independent programmable sample preparation and analysis system |
| MX2008015425A (es) * | 2006-06-02 | 2008-12-12 | Pfizer Prod Inc | Ensayo de celulas tumorales circulantes. |
| EP2589668A1 (fr) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Analyse de cellules rares utilisant la division d'échantillons et les marqueurs d'ADN |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| WO2007147074A2 (fr) | 2006-06-14 | 2007-12-21 | Living Microsystems, Inc. | Utilisation de génotypage snp fortement parallèle pour diagnostic fœtal |
| CN101583722A (zh) | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | 从生物学样品检测稀有细胞的方法和组合物 |
| CN101669031A (zh) * | 2007-02-27 | 2010-03-10 | 森托科隆股份公司 | 使用与细胞外标记物结合的试剂组多重检测肿瘤细胞 |
| GB2461476B (en) | 2007-04-16 | 2012-02-22 | Immunivest Corp | A rapid, semi-automated method to detect respiratory virus infected cells in direct specimens |
| US8003314B2 (en) | 2007-04-16 | 2011-08-23 | Diagnostic Hybrids, Inc. | Methods for direct fluorescent antibody virus detection in liquids |
| US8110101B2 (en) | 2007-08-30 | 2012-02-07 | Veridex, Llc | Method and apparatus for imaging target components in a biological sample using permanent magnets |
| US7828968B2 (en) | 2007-08-30 | 2010-11-09 | Veridex, Llc | Method and apparatus for imaging target components in a biological sample using permanent magnets |
| US8071395B2 (en) | 2007-12-12 | 2011-12-06 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and apparatus for magnetic separation of cells |
| HUE031848T2 (en) | 2008-09-20 | 2017-08-28 | Univ Leland Stanford Junior | Non-invasive diagnosis of fetal aneuploidy by sequencing |
| US11634747B2 (en) | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| DE202010018569U1 (de) | 2009-02-18 | 2017-09-26 | Streck Inc. | Konservierung zellfreier Nukleinsäuren |
| US20130023433A1 (en) | 2009-09-28 | 2013-01-24 | Yuling Luo | Methods of detecting nucleic acid sequences with high specificity |
| EP3045918B1 (fr) * | 2009-10-21 | 2017-12-06 | The Scripps Research Institute | Méthodes d'utilisation de cellules non rares pour détecter des cellules rares |
| US20130171621A1 (en) | 2010-01-29 | 2013-07-04 | Advanced Cell Diagnostics Inc. | Methods of in situ detection of nucleic acids |
| WO2011099565A1 (fr) * | 2010-02-10 | 2011-08-18 | シスメックス株式会社 | Méthode de détection de cellules cancéreuses dans le sang et programme utilisé à cet effet |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12545960B2 (en) | 2010-05-18 | 2026-02-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| EP2572003A4 (fr) | 2010-05-18 | 2016-01-13 | Natera Inc | Procédés de classification de ploïdie prénatale non invasive |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| DE102010020785A1 (de) * | 2010-05-18 | 2011-11-24 | Siemens Aktiengesellschaft | Vorrichtung und Verfahren zum Erkennen von magnetisch markierten Mikroobjekten |
| WO2012088456A2 (fr) | 2010-12-22 | 2012-06-28 | Natera, Inc. | Procédés de recherche de paternité prénatale, non invasive |
| AU2011358564B9 (en) | 2011-02-09 | 2017-07-13 | Natera, Inc | Methods for non-invasive prenatal ploidy calling |
| US20120252038A1 (en) * | 2011-04-01 | 2012-10-04 | Chianese David A | Steroid receptor assays |
| US9956281B2 (en) | 2011-05-04 | 2018-05-01 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
| US20140295426A1 (en) * | 2011-07-28 | 2014-10-02 | Veridex Llc | Methods for Diagnosing Cancer by Characterization of Tumor Cells Associated with Pleural or Serous Fluids |
| JP6329072B2 (ja) | 2011-09-26 | 2018-05-23 | キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング | 細胞外核酸の安定化および単離 |
| US11021733B2 (en) | 2011-09-26 | 2021-06-01 | Qiagen Gmbh | Stabilization and isolation of extracellular nucleic acids |
| CN103827303B (zh) | 2011-09-26 | 2021-10-22 | 普瑞阿那利提克斯有限公司 | 细胞外核酸的稳定化和分离 |
| KR102037891B1 (ko) * | 2012-03-09 | 2019-10-30 | 한국전자통신연구원 | 다중 분리 장치 및 혈중 암세포 분리 방법 |
| EP2848935A4 (fr) | 2012-05-10 | 2015-12-09 | Konica Minolta Inc | Procédé d'élimination des globules rouges ainsi que tube de centrifugation pour prélèvement sanguin |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| CN104755628B (zh) | 2012-09-25 | 2019-03-01 | 凯杰有限公司 | 生物样品的稳定化 |
| US12590955B2 (en) | 2013-03-15 | 2026-03-31 | Zeon Corporation | Methods and systems for processing particles |
| EP3569313A1 (fr) | 2013-03-15 | 2019-11-20 | GPB Scientific, LLC | Traitement microfluidique sur puce de particules |
| US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
| EP3608022A1 (fr) | 2013-03-15 | 2020-02-12 | The Trustees of Princeton University | Procédés et dispositifs de purification à haut rendement |
| US11525155B2 (en) | 2013-03-18 | 2022-12-13 | Qiagen Gmbh | Stabilisation of biological samples |
| JP6407248B2 (ja) * | 2013-03-18 | 2018-10-17 | キアゲン ゲーエムベーハー | 細胞外核酸の安定化および単離 |
| ES2938048T3 (es) | 2013-07-24 | 2023-04-04 | Streck Llc | Composiciones y procedimientos para estabilizar las células tumorales circulantes |
| EP3502270B1 (fr) | 2013-10-21 | 2020-03-18 | The General Hospital Corporation | Procédés relatifs à des groupes de cellules tumorales circulantes et au traitement du cancer |
| EA201691496A1 (ru) | 2014-01-27 | 2016-12-30 | Эпик Сайенсиз, Инк. | Диагностика биомаркеров рака предстательной железы с помощью циркулирующих опухолевых клеток |
| EA201691682A1 (ru) | 2014-02-21 | 2017-02-28 | Эпик Сайенсиз, Инк. | Способы анализирования редких циркулирующих в крови клеток |
| JP6664332B2 (ja) * | 2014-03-18 | 2020-03-13 | キアゲン ゲーエムベーハー | 細胞外核酸の安定化および単離 |
| CN103940997B (zh) * | 2014-03-21 | 2017-01-04 | 上海柏慧康生物科技有限公司 | 一种乳腺癌循环肿瘤细胞检测系统及试剂盒 |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| EP3957749A1 (fr) | 2014-04-21 | 2022-02-23 | Natera, Inc. | Détection de mutations spécifiques d'un tumeur dans les biopsies par séquençage exome entier et dans les échantillons acellulaires |
| CN103980365A (zh) * | 2014-06-03 | 2014-08-13 | 国家纳米科学中心 | 一种表面固载炭疽致死因子的磁性纳米粒子、其制备方法及用途 |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| EP3164204B1 (fr) * | 2014-07-02 | 2021-03-10 | Siemens Healthcare Diagnostics Inc. | Séparation d'acides nucléiques sélective |
| EP3262195A1 (fr) * | 2015-02-24 | 2018-01-03 | Siemens Healthcare Diagnostics Inc. | Préfixation permettant d'augmenter la récupération de cellules rares |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| WO2016183106A1 (fr) | 2015-05-11 | 2016-11-17 | Natera, Inc. | Procédés et compositions pour la détermination de la ploïdie |
| US20170097361A1 (en) * | 2015-07-15 | 2017-04-06 | Streck, Inc. | Method and device for stabilizing of proteins |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| JP6617495B2 (ja) * | 2015-09-18 | 2019-12-11 | 東ソー株式会社 | 腫瘍細胞の検出方法 |
| WO2017079212A1 (fr) * | 2015-11-04 | 2017-05-11 | Axon Dx, Llc | Détection, capture, analyse et agrégation de cellules, et procédés et appareil de transmission de données |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| EP3377645B1 (fr) | 2015-11-20 | 2023-10-04 | Qiagen GmbH | Procédé de préparation de compositions stérilisées pour stabiliser des acides nucléiques extracellulaires |
| CN105372109A (zh) * | 2015-12-15 | 2016-03-02 | 苏州药明康德新药开发股份有限公司 | 添加稳定剂的生物基质的制备方法 |
| WO2017152028A1 (fr) * | 2016-03-04 | 2017-09-08 | Janssen Diagnostics, Llc | Conservation de composants cellulaires de cellules avec un conservateur |
| JP7064665B2 (ja) * | 2016-03-07 | 2022-05-11 | ファーザー フラナガンズ ボーイズ ホーム ドゥーイング ビジネス アズ ボーイズ タウン ナショナル リサーチ ホスピタル | 非侵襲的分子対照 |
| WO2017181202A2 (fr) | 2016-04-15 | 2017-10-19 | Natera, Inc. | Procédés de détection du cancer du poumon |
| JP2017219479A (ja) | 2016-06-09 | 2017-12-14 | 住友電気工業株式会社 | 微小粒子計測装置及び分析方法 |
| EP4656715A3 (fr) | 2016-07-29 | 2026-02-25 | Streck LLC | Composition de suspension pour contrôle d'analyse hématologique |
| US11485996B2 (en) | 2016-10-04 | 2022-11-01 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| KR102313431B1 (ko) | 2016-11-21 | 2021-10-18 | 나노스트링 테크놀로지스, 인크. | 화학적 조성물 및 이것을 사용하는 방법 |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| PL3662080T3 (pl) * | 2017-08-02 | 2022-04-19 | Sarstedt Ag & Co. Kg | Sposób i formulacja do stabilizacji bezkomórkowych kwasów nukleinowych i komórek |
| EP3675876A4 (fr) | 2017-09-01 | 2021-06-02 | GPB Scientific, Inc. | Procédés de préparation de cellules thérapeutiquement actives au moyen de la microfluidique |
| CN115119829B (zh) * | 2017-10-19 | 2024-07-12 | 斯特雷克股份有限公司 | 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物 |
| JP2021506342A (ja) | 2017-12-14 | 2021-02-22 | ティーエーアイ ダイアグノスティックス インコーポレイテッドTai Diagnostics,Inc. | 移植のための移植片適合性の評価 |
| CA3090426A1 (fr) | 2018-04-14 | 2019-10-17 | Natera, Inc. | Procedes de detection et de surveillance du cancer au moyen d'une detection personnalisee d'adn tumoral circulant |
| AU2019271028B2 (en) | 2018-05-14 | 2025-09-18 | Bruker Spatial Biology, Inc. | Chemical compositions and methods of using same |
| JP7334468B2 (ja) * | 2018-05-29 | 2023-08-29 | 東ソー株式会社 | 血液試料保存剤 |
| JP7036670B2 (ja) | 2018-05-31 | 2022-03-15 | アークレイ株式会社 | 血液中の稀少細胞検査、該検査ための血液処理方法及び採血管 |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| CN108865976B (zh) * | 2018-07-19 | 2022-06-28 | 复旦大学附属中山医院 | 一种离散汲取收集外泌体(exosome)的方法及试剂 |
| CN110250159A (zh) * | 2019-05-28 | 2019-09-20 | 天津中科生物科技有限公司 | 一种细胞保护液及其制备方法和应用 |
| EP3980559A1 (fr) | 2019-06-06 | 2022-04-13 | Natera, Inc. | Procédés de détection d'adn de cellules immunitaires et de surveillance du système immunitaire |
| KR20240168912A (ko) * | 2022-03-25 | 2024-12-02 | 세키스이 메디칼 가부시키가이샤 | 순환 종양 세포 분리 키트, 순환 종양 세포 분리 용기 및 순환 종양 세포의 분리 방법 |
| WO2024238350A1 (fr) * | 2023-05-12 | 2024-11-21 | The Children's Medical Center Corporation | Multi-omique régulatrice à cellule unique avec profilage de mutation mitochondriale profonde (redeem) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2475737A1 (fr) * | 1980-02-07 | 1981-08-14 | Pasteur Institut | Perfectionnements apportes aux procedes de conservation d'hematies par lyophilisation en vue de leur utilisation dans des reactions d'hemagglutination et hematies non agglutinables spontanement obtenues par ce procede |
| US4404181A (en) * | 1981-10-15 | 1983-09-13 | Cambridge Chemical Products, Inc. | Extended-life tissue fixative composition and method of using the same |
| EP0161770A2 (fr) * | 1984-05-14 | 1985-11-21 | Becton Dickinson and Company | Agent de lyse pour l'analyse de cellules sanguines périphériques |
| WO1993005650A1 (fr) * | 1991-09-20 | 1993-04-01 | Camiener Gerald W | Procedes et compositions comportant une solution de stabilisation a l'aldehyde |
| WO1994018828A1 (fr) * | 1993-02-25 | 1994-09-01 | Abbott Laboratories | Systeme de reactifs polyvalent de lyse rapide d'echantillon de sang total |
| WO1997008557A1 (fr) * | 1995-08-28 | 1997-03-06 | Miltenyi Biotech Gmbh | Procede efficace d'enrichissement et de detection de cellules tumorales disseminees |
| WO1997045729A1 (fr) * | 1996-05-24 | 1997-12-04 | Northern General Hospital Nhs Trust | Liquide servant a recueillir un specimen |
| US5849517A (en) * | 1991-05-08 | 1998-12-15 | Streck Laboratories, Inc. | Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same |
| US6197523B1 (en) * | 1997-11-24 | 2001-03-06 | Robert A. Levine | Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4040785A (en) * | 1976-10-18 | 1977-08-09 | Technicon Instruments Corporation | Lysable blood preservative composition |
| US4320111A (en) * | 1977-06-14 | 1982-03-16 | American Home Products Corporation | Immunologic compositions methods of preparation and use |
| FR2523810B1 (fr) * | 1982-03-23 | 1988-11-25 | Carpentier Alain | Tissu biologique greffable et procede pour sa preparation |
| FR2528848A1 (fr) * | 1982-06-16 | 1983-12-23 | Sanofi Sa | Nouveau derive de thieno-pyridone, son procede de preparation et son application therapeutique |
| EP0156537A3 (fr) * | 1984-03-02 | 1987-05-13 | Board Of Regents University Of Texas System | Fluide magnétique biologique |
| US4788139A (en) * | 1987-08-06 | 1988-11-29 | Streck Laboratories, Inc. | Platelet aggregation reagent, reagent container and method of determining platelet aggregation in EDTA-anticoagulated blood |
| US5385707A (en) * | 1988-12-28 | 1995-01-31 | Stefan Miltenyi | Metal matrices for use in high gradient magnetic separation of biological materials and method for coating the same |
| US5698271A (en) * | 1989-08-22 | 1997-12-16 | Immunivest Corporation | Methods for the manufacture of magnetically responsive particles |
| US6670197B2 (en) * | 1997-11-24 | 2003-12-30 | David L. Rimm | Method for assaying whole blood for the presence or absence of circulating cancer or other target cell fragments |
| WO1999041613A1 (fr) * | 1998-02-12 | 1999-08-19 | Immunivest | Methodes et reactifs pour l'isolation rapide et efficace de cellules cancereuses circulantes |
| AU2876900A (en) * | 1999-02-10 | 2000-08-29 | Cell Works Inc. | Class characterization of circulating cancer cells isolated from body fluids andmethods of use |
| WO2001019956A2 (fr) * | 1999-09-13 | 2001-03-22 | Bander Neil H | Procede d'isolement de cellules epitheliales prostatiques du sperme |
| EP1425294B2 (fr) * | 2001-08-23 | 2012-12-12 | Veridex, LLC | Analyse de cellules tumorales en circulation, de fragments et de debris associes |
-
2002
- 2002-08-23 EP EP02761478A patent/EP1425294B2/fr not_active Expired - Lifetime
- 2002-08-23 BR BR0212124-7A patent/BR0212124A/pt not_active Application Discontinuation
- 2002-08-23 BR BR0212125-5A patent/BR0212125A/pt not_active IP Right Cessation
- 2002-08-23 JP JP2003523608A patent/JP2005501236A/ja active Pending
- 2002-08-23 CN CNA028212002A patent/CN1596265A/zh active Pending
- 2002-08-23 WO PCT/US2002/026861 patent/WO2003019141A2/fr not_active Ceased
- 2002-08-23 EP EP02768676A patent/EP1425383A4/fr not_active Withdrawn
- 2002-08-23 KR KR10-2004-7002572A patent/KR20040030984A/ko not_active Withdrawn
- 2002-08-23 DE DE60227678T patent/DE60227678D1/de not_active Expired - Lifetime
- 2002-08-23 CA CA2457891A patent/CA2457891C/fr not_active Expired - Fee Related
- 2002-08-23 IL IL16020902A patent/IL160209A0/xx unknown
- 2002-08-23 CA CA2457894A patent/CA2457894C/fr not_active Expired - Fee Related
- 2002-08-23 JP JP2003523961A patent/JP2005502863A/ja active Pending
- 2002-08-23 CN CNA02820820XA patent/CN1571634A/zh active Pending
- 2002-08-23 IL IL16021002A patent/IL160210A0/xx unknown
- 2002-08-23 AT AT02761478T patent/ATE401574T1/de not_active IP Right Cessation
- 2002-08-23 KR KR10-2004-7002473A patent/KR20040053115A/ko not_active Withdrawn
- 2002-08-23 WO PCT/US2002/026867 patent/WO2003018757A2/fr not_active Ceased
-
2008
- 2008-12-24 AU AU2008288601A patent/AU2008288601B2/en not_active Ceased
-
2009
- 2009-01-02 AU AU2009200013A patent/AU2009200013B2/en not_active Ceased
- 2009-01-21 JP JP2009011194A patent/JP2009109514A/ja active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2475737A1 (fr) * | 1980-02-07 | 1981-08-14 | Pasteur Institut | Perfectionnements apportes aux procedes de conservation d'hematies par lyophilisation en vue de leur utilisation dans des reactions d'hemagglutination et hematies non agglutinables spontanement obtenues par ce procede |
| US4404181A (en) * | 1981-10-15 | 1983-09-13 | Cambridge Chemical Products, Inc. | Extended-life tissue fixative composition and method of using the same |
| EP0161770A2 (fr) * | 1984-05-14 | 1985-11-21 | Becton Dickinson and Company | Agent de lyse pour l'analyse de cellules sanguines périphériques |
| US5849517A (en) * | 1991-05-08 | 1998-12-15 | Streck Laboratories, Inc. | Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same |
| WO1993005650A1 (fr) * | 1991-09-20 | 1993-04-01 | Camiener Gerald W | Procedes et compositions comportant une solution de stabilisation a l'aldehyde |
| WO1994018828A1 (fr) * | 1993-02-25 | 1994-09-01 | Abbott Laboratories | Systeme de reactifs polyvalent de lyse rapide d'echantillon de sang total |
| WO1997008557A1 (fr) * | 1995-08-28 | 1997-03-06 | Miltenyi Biotech Gmbh | Procede efficace d'enrichissement et de detection de cellules tumorales disseminees |
| WO1997045729A1 (fr) * | 1996-05-24 | 1997-12-04 | Northern General Hospital Nhs Trust | Liquide servant a recueillir un specimen |
| US6197523B1 (en) * | 1997-11-24 | 2001-03-06 | Robert A. Levine | Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood |
Also Published As
| Publication number | Publication date |
|---|---|
| BR0212125A (pt) | 2005-06-28 |
| AU2008288601B2 (en) | 2012-05-31 |
| AU2009200013A1 (en) | 2009-02-05 |
| AU2009200013B2 (en) | 2012-03-08 |
| WO2003019141A2 (fr) | 2003-03-06 |
| EP1425383A2 (fr) | 2004-06-09 |
| AU2008288601A1 (en) | 2009-04-02 |
| IL160209A0 (en) | 2004-07-25 |
| JP2009109514A (ja) | 2009-05-21 |
| KR20040053115A (ko) | 2004-06-23 |
| ATE401574T1 (de) | 2008-08-15 |
| JP2005501236A (ja) | 2005-01-13 |
| JP2005502863A (ja) | 2005-01-27 |
| EP1425294B2 (fr) | 2012-12-12 |
| KR20040030984A (ko) | 2004-04-09 |
| WO2003018757A3 (fr) | 2003-09-12 |
| WO2003019141A3 (fr) | 2004-04-01 |
| BR0212124A (pt) | 2004-07-20 |
| CN1571634A (zh) | 2005-01-26 |
| CA2457894A1 (fr) | 2003-03-06 |
| EP1425294A4 (fr) | 2005-11-16 |
| EP1425294A2 (fr) | 2004-06-09 |
| IL160210A0 (en) | 2004-07-25 |
| WO2003018757A2 (fr) | 2003-03-06 |
| CA2457894C (fr) | 2014-07-08 |
| EP1425294B1 (fr) | 2008-07-16 |
| CN1596265A (zh) | 2005-03-16 |
| CA2457891C (fr) | 2019-10-01 |
| DE60227678D1 (de) | 2008-08-28 |
| CA2457891A1 (fr) | 2003-03-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1425383A4 (fr) | Stabilisation de cellules et de specimens biologiques pour l'analyse | |
| van der Horst et al. | Current perspectives of CASA applications in diverse mammalian spermatozoa | |
| Mason et al. | The use of phloxine B and rose bengal stains to facilitate sorting benthic samples | |
| Jørgensen et al. | Identification, isolation and analysis of human gut-associated lymphoid tissues | |
| Skala et al. | Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues | |
| Hsieh et al. | High speed detection of circulating tumor cells | |
| US9134237B2 (en) | High sensitivity multiparameter method for rare event analysis in a biological sample | |
| Li et al. | A microfluidic device and automatic counting system for the study of C. elegans reproductive aging | |
| NZ333830A (en) | Method for assessing chemosensitivity of a biopsy sample | |
| WO2008109414A3 (fr) | Utilisation de la fluorescence endogène pour identifier les cellules de tumeur du sein métastatiques envahissantes | |
| Markovic et al. | A computer vision approach to rare cell in vivo fluorescence flow cytometry | |
| Tejerina et al. | Routine assessment of motility of ejaculated stallion spermatozoa using a novel computer-assisted motility analyzer (Qualisperm™) | |
| Fang et al. | Quantitative assessment of microenvironment characteristics and metabolic activity in glioma via multiphoton microscopy | |
| Monferini et al. | Age-dependent high-yield isolation of primordial, primary, and early secondary follicles from the bovine ovarian cortex | |
| Toman | What are the advantages and disadvantages of fluorescence microscopy | |
| Zver et al. | Validation of an automated technique for ovarian cortex dissociation: isolation of viable ovarian cells and their qualification by multicolor flow cytometry | |
| Li et al. | Flow cytometric and near-infrared Raman spectroscopic investigation of quality in stained, sorted, and frozen-thawed buffalo sperm | |
| Kanehira et al. | FISH diagnosis of acute graft-versus-host disease following living-related liver transplant | |
| Tiano et al. | Assessment of DNA damage in Down Syndrome patients by means of a new, optimised single cell gel electrophoresis technique | |
| Edengeiser et al. | Non-invasive chemical assessment of living human spermatozoa | |
| Gong et al. | Clonal status and clinicopathological features of Langerhans cell histiocytosis | |
| Adamczyk et al. | MitoBADY-based Raman sensing of neutrophil-like cells | |
| Liu et al. | Quantitative single-particle profiling of extracellular vesicles via fluorescent nanoparticle tracking analysis | |
| Managò et al. | Identification and classification of acute lymphoblastic leukemia cells from peripheral blood by using Raman spectroscopy | |
| Balasubramanian et al. | Isolation and characterization of circulating tumor cells (CTCs) from peripheral blood specimens of patients with advanced solid tumor malignancies (using ApoStream (TM) instrumentation) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20040315 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7A 01N 1/02 A |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20050927 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7A 01N 1/02 B Ipc: 7G 01N 33/574 B Ipc: 7G 01N 33/543 A |
|
| 17Q | First examination report despatched |
Effective date: 20060623 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20080508 |