EP1434519A2 - Dispositif a introduire dans des organes corporels creux - Google Patents

Dispositif a introduire dans des organes corporels creux

Info

Publication number
EP1434519A2
EP1434519A2 EP02782853A EP02782853A EP1434519A2 EP 1434519 A2 EP1434519 A2 EP 1434519A2 EP 02782853 A EP02782853 A EP 02782853A EP 02782853 A EP02782853 A EP 02782853A EP 1434519 A2 EP1434519 A2 EP 1434519A2
Authority
EP
European Patent Office
Prior art keywords
measuring device
measuring
blood
hollow body
pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02782853A
Other languages
German (de)
English (en)
Inventor
Werner Prof. Dr. Med. Schregel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1434519A2 publication Critical patent/EP1434519A2/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/0265—Measuring blood flow using electromagnetic means, e.g. electromagnetic flowmeter
    • A61B5/027—Measuring blood flow using electromagnetic means, e.g. electromagnetic flowmeter using catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
    • A61B5/028—Measuring blood flow using tracers, e.g. dye dilution by thermo-dilution

Definitions

  • the invention relates to a device for insertion into hollow body organs, in particular in blood vessels, consisting of an essentially elongated instrument with at least one measuring device located in an end of the device which is closed in the region of the end of the device inserted into the hollow body organ, in particular the bloodstream.
  • Known devices are designed as catheters and are used to dispense liquids in hollow body organs such. B. to inject blood streams or to take samples from hollow body organs. Special instruments are required for insertion into the hollow organ of the body, since the catheters are, for example, not suitable for penetrating tissue layers due to their flexible design.
  • a measuring device is partially provided in the catheters. Using this known measuring device, amounts of air in liquids, such as. B. in blood. If the operator wants z. B. get more information about the composition of the blood or the amount of air detected, the correspondingly detected gas or blood must be extracted. The surgeon also receives none, for example, using the previously known device further information. For example, if the surgeon wants to get more information about blood pressure, he has to use other instruments, some of which have to be inserted into the patient's body.
  • the object of the invention is therefore to improve and specify a previously known device that is more versatile.
  • a suitable measuring device for measuring the composition and / or the properties of the blood.
  • the body's own laboratory values e.g. Hemoglobin, oxygen saturation, electrolytes, blood gases, viscosity are determined.
  • concentration of gases or chemicals e.g. Medications or indicator dyes to be determined so that when the values fall below certain values, the missing substances can be added in an optimal dosage that is tailored to the patient to be treated.
  • the measuring device can be inserted in a channel closed at the end, it does not come into contact with the medium to be examined, such as, for. B. blood and is recyclable. After use, the measuring device can be easily pulled out of the inlet or the channel and simply inserted into a new device.
  • the measuring device can be designed as an optical measuring device and the instrument can be made of a material that is transparent to the measurement of optical radiation and enables an optical measurement, at least in the area of the measuring device.
  • the Instrument for example, have a window that enables optical detection. It is Z. B. also possible that the entire instrument consists of an optically transparent material.
  • the instrument can have a semi-permeable membrane in the measuring range.
  • a semi-permeable membrane allows ions to pass through for the examination of the body's laboratory values; however, the passage of blood, proteins, infectious agents or other substances is prevented, so that the measuring device is nevertheless recyclable.
  • measuring devices are conceivable, consisting of a transmitter and a receiver, it being possible to draw conclusions about the substance to be examined on the basis of the refraction behavior of emitted and received light beams.
  • Optical measuring devices are also conceivable in which light beams of different wavelengths are emitted and at least partially reflected, so that conclusions about substances in the blood are possible.
  • Measuring devices suitable for spectroscopy are also conceivable.
  • the measuring device can also be integrated in a chip, designed as a chip or connected to it.
  • a suitable measuring device can be provided for measuring the temperature of the blood flowing in the bloodstream and / or values that can be determined by temperature measurement (s), in particular the flow rate.
  • the instrument consists of a material that enables temperature measurement.
  • this measuring device can be used together with a measuring device.
  • device for measuring the composition and / or the properties of the blood can be provided in a device according to the invention. Since the measuring device can be inserted in a channel closed at the end, it does not come into contact with the medium to be examined, such as, for. B. blood and is recyclable. After use, the measuring device can be easily pulled out of the insertion and can easily be inserted into a new device.
  • the measuring device can be designed as a temperature measuring device and / or as a heat flow sensor.
  • the temperature measuring device consists, for example, of temperature sensors arranged at a distance from one another, a temperature sensor being spaced apart from the medium to be measured via an additional insulating material.
  • the measured difference allows conclusions to be drawn about the flow rate, which in turn provides an indication of the blood flow to the organs. In this way, the volume can also be determined.
  • B. is promoted by the heart within a certain time interval.
  • Thermocouples for example, can be used as the temperature measuring device.
  • the measuring device can also be integrated in a chip, designed as a chip or connected to it.
  • a suitable measuring device can be provided for measuring hemodynamic parameters of the blood and / or values that can be determined by pressure measurement (s).
  • This measuring device can be used together with a measuring device for measuring the The composition and / or the properties of the blood and / or a measuring device for measuring the temperature and / or values which can be determined by temperature measurement can be provided in the device according to the invention. Since the measuring device can be inserted in a channel closed at the end, it does not come into contact with the medium to be examined, such as, for. B. blood and is recyclable. After use, the measuring device can be easily pulled out of the insertion and can easily be inserted into a new device.
  • Hemodynamic parameters are understood to mean, for example, blood pressure, cardiac rhythm or cardiac output.
  • Particles in the blood such as e.g. B. embolisms, blood clots, bone fragments, bone cement or fats can be determined.
  • conclusions can be drawn about the flow rate and the cardiac output by measuring such quantities.
  • the measuring device can be designed for the measurement of pressure, in particular of reflected sound pressure of a sound generator, and the instrument can have an area that transmits pressure at least in the area of the measuring device.
  • the pressure measuring device can be designed as a pressure sensor, in particular a piezo element. However, pressure transducers operating on a magnetic basis or pressure transducers designed as microphones are also conceivable.
  • the pressure measuring device can also be designed as an ultrasound probe. It is possible for a plurality of such measuring devices to be arranged at a distance from one another in the longitudinal direction. In this case, one makes use of the so-called "Doppler effect", in which the frequency change between the waves emitted by the receiver and received by the receiver is determined.
  • the measuring device can also be integrated in a chip, designed as a chip or connected to it.
  • the data determined or measured by the respective measuring device and / or the chip can be passed in different ways to a control and display device located outside the device, so that the user can record the data relevant to him. In the simplest embodiment, this is done via a cable connection. Transmission via radio or infrared is also conceivable. If a chip is provided, a memory is advantageous since the data can then also be archived. It is also possible that - if the data does not have to be read simultaneously - it can only be called up after the treatment and then analyzed.
  • a device that generates and sends out pulses preferably cardiac pacemaker pulses, can also be provided in the instrument.
  • the device can be integrated in a chip, designed as a chip or connected to it.
  • at least one infusion or suction channel the end region of which in the bloodstream has at least one opening, can be provided. This proves to be advantageous since liquids can then be aspirated via the instrument or drugs or solutions can be injected into the hollow body in question.
  • the device is rigid and has a tip at the end to be inserted into the hollow body organ.
  • the instrument according to the invention is also suitable for tissue layers such. B. to penetrate the skin so that it does not require a separate instrument for inserting the device according to the invention into the hollow body to be examined.
  • the closed end channel or another closed channel can be used for therapeutic temperature influencing, for. B. by means of an introduced heating and / or cooling element or introduction of a particularly circulating tempering medium.
  • the cooling element can, for example, be brought to the desired temperature before insertion.
  • a temperature control medium is advantageously circulated in the temperature control element, so that the temperature control medium can be continuously brought to the desired temperature by a corresponding temperature control device.
  • the temperature control medium it is also possible for the temperature control medium to be fed directly into the channel.
  • a partition wall extending along the channel is preferably provided in the channel.
  • the partition preferably has a recess in the region of the closed end, so that the channel has an approximately U-shaped course and thus the temperature control medium, such as z. B. a hot or cold saline solution can circulate.
  • the instrument according to the invention is suitable for both venous and arterial use.
  • the instrument according to the invention can also be used for examination in the heart.
  • FIG. 1 is a side view of a device according to the invention
  • FIG. 2 shows a section through a device with an infusion or suction channel and at least one integrated measuring device
  • FIG 3 shows a section through a device with an infusion or suction channel and a channel closed at the end, in which at least one recyclable measuring device is inserted, and
  • FIG. 4 shows a section through a device with an infusion or suction channel and two channels closed at the ends, in each of which at least one measuring device is inserted.
  • FIG. 1 shows a device 1, which consists of an essentially tubular instrument.
  • the device 1 is a catheter which is inserted into a bloodstream (not shown), one end 2, with which the device 1 is inserted into a bloodstream, being designed in the manner of a truncated cone.
  • Measuring devices 3 are provided at a distance from the end 2 of the device 1.
  • the measuring devices 3 are advantageously arranged in such a way that the radiation angles - if they are provided, for example, for measuring the gas and / or drug concentration - overlap so that the entire vascular volume of the bloodstream can be monitored.
  • measuring devices 3 there are a total of three measuring devices 3 in the device 1, advantageously a measuring device for measuring the composition and / or properties of the blood, a measuring device for measuring the temperature and / or values that can be determined by temperature measurement, and a measuring device for measuring hemodynamic parameters and / or of values that can be determined by pressure measurement.
  • the device 1 Since the device 1 is simultaneously designed as a catheter, there are lateral openings 4 between the measuring devices 3 and the end 2 of the device 1 and in the area of the end 2, an end opening 5 is provided which is connected to an infusion or suction channel 6, as shown in FIG. 2.
  • the other end of the device 1 is connected to a conventional infusion or suction device, not shown, for the infusion or suction channel 6, and to a control and display device, also not shown, for the measuring devices 3.
  • the device 1 Before an operative intervention, the device 1 is inserted with its end 2 into a bloodstream (not shown) and placed at the desired examination site. Via the openings 4 and 5, substances such as. B. drugs, injected or aspirated samples, while measurements can be made on the measuring device 3 at the same time.
  • FIG. 2 shows a variant of the device 1 according to the invention, in which the measuring devices 3 are permanently integrated in the device 1.
  • the measuring device 3 shown by way of example in FIG. 2 consists of a receiver and a transmitter, which are arranged at an angle to one another.
  • the waves emitted by the transmitter are reflected by the liquid or any air bubbles present and received again by the receiver.
  • the reflected medium i. H. Liquid or air bubbles
  • differences in the frequency of the transmitted and received waves so that by means of this technique, e.g. B. particles in the blood such. B. bone fragments can be detected.
  • the measuring devices 3 shows an embodiment of the device 1 in which the measuring devices 3 are located in a device 1 arranged end closed channel 7 are located. Since the channel 7 is closed at the end, the measuring devices 3 arranged and displaceable therein do not come into contact with the liquid to be monitored and flowing around the device 1. After the operation, the measuring devices 3 are pulled out of the channel (7) of the device 1 and can be used in a new device 1 and thus reused without the need for expensive sterilization. Here too, the infusion or suction channel 6 is arranged in the other half of the device 1.
  • the various required measuring devices 3 can optionally be introduced in the device 1 with a channel 7, so that each device 1 can be optimally adapted to the specific application.
  • the infusion or suction channel 6 is arranged in the center, with channels 7 closed on both ends being provided on both sides of the infusion or suction channel. Measuring devices 3 are introduced into these channels 7. No further explanation is required that several measuring devices 3 can be provided in each channel 7.
  • a pulse generating and emitting device can be provided in the channel 7. This is useful, for example, in cardiac surgery in which cardiac activity is to be stabilized.
  • the device 1 shown in FIGS. 1 to 4 is a catheter. It goes without saying lent that the device 1 can also be designed as a needle, in which case the end 2 is pointed. In such an embodiment, the device 1 is also suitable for piercing tissue.
  • drugs can be added in doses, while the drug concentration in the relevant body organ is determined at the same time.
  • the device 1 is designed as a needle, no lateral openings 4 are required.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Vascular Medicine (AREA)
  • Electromagnetism (AREA)
  • Hematology (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

L'invention concerne un dispositif à introduire dans des organes corporels creux, notamment dans des vaisseaux sanguins. Ce dispositif comprend un instrument sensiblement longitudinal doté d'un dispositif de mesure se trouvant dans un canal fermé situé dans la zone de l'extrémité introduite dans l'organe corporel creux, notamment dans le vaisseau sanguin. L'invention vise à perfectionner un dispositif connu et à le rendre plus polyvalent. A cet effet, le dispositif de mesure doit être apte à mesurer la composition et/ou les propriétés du sang et/ou la température du sang coulant dans le vaisseau sanguin et/ou des valeurs pouvant être déterminées par mesure(s) thermique(s), notamment la vitesse d'écoulement, et/ou des paramètres hémodynamiques du sang et/ou des valeurs pouvant être déterminées par mesure(s) de pression.
EP02782853A 2001-10-08 2002-10-08 Dispositif a introduire dans des organes corporels creux Withdrawn EP1434519A2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE20116460U DE20116460U1 (de) 2001-10-08 2001-10-08 Einrichtung zum Einführen in Körperhohlorgane
DE20116460U 2001-10-08
PCT/EP2002/011242 WO2003030706A2 (fr) 2001-10-08 2002-10-08 Dispositif a introduire dans des organes corporels creux

Publications (1)

Publication Number Publication Date
EP1434519A2 true EP1434519A2 (fr) 2004-07-07

Family

ID=7962596

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02782853A Withdrawn EP1434519A2 (fr) 2001-10-08 2002-10-08 Dispositif a introduire dans des organes corporels creux

Country Status (6)

Country Link
US (1) US20050020890A1 (fr)
EP (1) EP1434519A2 (fr)
JP (1) JP2005504599A (fr)
AU (1) AU2002346970A1 (fr)
DE (1) DE20116460U1 (fr)
WO (1) WO2003030706A2 (fr)

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WO2004026128A1 (fr) * 2002-09-17 2004-04-01 Diametrics Medical Limited Appareil et methode de controle de l'etat pathologique d'un patient
US20090043184A1 (en) * 2007-08-08 2009-02-12 Edwards Lifesciences Corporation Catheter and probe for measuring analytes or other parameters
EP2501286A4 (fr) 2009-11-16 2013-09-04 Maquet Critical Care Ab Système de mesure pour un écoulement autonome
DE102011008051A1 (de) * 2011-01-07 2012-07-12 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Bereich Universitätsmedizin Absaugvorrichtung
CN104619241A (zh) * 2012-08-30 2015-05-13 西门子公司 活体确定检查对象内的至少一个血液值的装置和方法
KR101811136B1 (ko) * 2016-07-26 2017-12-20 이화여자대학교 산학협력단 신체 조직의 내면 및 내강을 냉각시키는 카테터
CN111683589B (zh) * 2018-02-05 2024-05-10 迈迪瑞股份公司 具有导管和传感器的设备

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Also Published As

Publication number Publication date
WO2003030706A3 (fr) 2003-12-24
AU2002346970A1 (en) 2003-04-22
JP2005504599A (ja) 2005-02-17
DE20116460U1 (de) 2002-01-17
US20050020890A1 (en) 2005-01-27
WO2003030706A2 (fr) 2003-04-17

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