EP1438323A4 - Compositions de meningocoque assorties d'un adjuvant - Google Patents

Compositions de meningocoque assorties d'un adjuvant

Info

Publication number
EP1438323A4
EP1438323A4 EP02800481A EP02800481A EP1438323A4 EP 1438323 A4 EP1438323 A4 EP 1438323A4 EP 02800481 A EP02800481 A EP 02800481A EP 02800481 A EP02800481 A EP 02800481A EP 1438323 A4 EP1438323 A4 EP 1438323A4
Authority
EP
European Patent Office
Prior art keywords
meningocoque
adjuvant
compositions
meningocoque compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02800481A
Other languages
German (de)
English (en)
Other versions
EP1438323A2 (fr
Inventor
Derek O'hagan
Nicholas Valiante
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Novartis Vaccines and Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2002/010869 external-priority patent/WO2002080648A2/fr
Application filed by Novartis Vaccines and Diagnostics Inc filed Critical Novartis Vaccines and Diagnostics Inc
Publication of EP1438323A2 publication Critical patent/EP1438323A2/fr
Publication of EP1438323A4 publication Critical patent/EP1438323A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
EP02800481A 2001-10-03 2002-10-03 Compositions de meningocoque assorties d'un adjuvant Withdrawn EP1438323A4 (fr)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US254438 1988-10-06
US32692901P 2001-10-03 2001-10-03
US326929P 2001-10-03
PCT/US2002/010869 WO2002080648A2 (fr) 2001-04-05 2002-04-05 Augmentation de l'immunite des muqueuses a la suite d'un amorçage parenteral
WOPCT/US02/10869 2002-04-05
US37354702P 2002-04-17 2002-04-17
US373547P 2002-04-17
US38067702P 2002-05-13 2002-05-13
US380677P 2002-05-13
US25443802A 2002-09-24 2002-09-24
US0230423 2002-09-24
WOPCT/US02/30423 2002-09-24
PCT/US2002/031726 WO2003028661A2 (fr) 2001-10-03 2002-10-03 Compositions de meningocoque assorties d'un adjuvant

Publications (2)

Publication Number Publication Date
EP1438323A2 EP1438323A2 (fr) 2004-07-21
EP1438323A4 true EP1438323A4 (fr) 2007-08-01

Family

ID=32601151

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02800481A Withdrawn EP1438323A4 (fr) 2001-10-03 2002-10-03 Compositions de meningocoque assorties d'un adjuvant

Country Status (8)

Country Link
EP (1) EP1438323A4 (fr)
JP (1) JP4522699B2 (fr)
CN (1) CN100354297C (fr)
AU (1) AU2002334844B2 (fr)
BR (1) BR0213119A (fr)
CA (1) CA2462646C (fr)
NZ (1) NZ532274A (fr)
WO (1) WO2003028661A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
MXPA04011249A (es) * 2002-05-14 2005-06-06 Chiron Srl Vacunas mucosales con adyuvante de quitosano y antigenos meningococicos.
GB0302218D0 (en) 2003-01-30 2003-03-05 Chiron Sri Vaccine formulation & Mucosal delivery
US20060057160A1 (en) 2002-08-02 2006-03-16 Ralph Biemans Vaccine composition
EP2263687B1 (fr) 2002-12-27 2015-03-25 Novartis Vaccines and Diagnostics, Inc. Compositions immunogènes contenant des phospholipides
EP2172213B1 (fr) 2003-01-30 2013-04-03 Novartis AG Vaccins injectables contre les multiples serogroupes du meningocoque
CA2514667C (fr) * 2003-01-30 2013-01-08 Chiron Corporation Vaccin contre la grippe contenant un adjuvant
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
JP5557415B2 (ja) 2003-06-02 2014-07-23 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物
JP2007523173A (ja) * 2004-02-20 2007-08-16 イデラ ファーマシューティカルズ インコーポレイテッド 修飾免疫調節オリゴヌクレオチドにより誘導された強力な粘膜免疫応答
EP1812056B1 (fr) * 2004-11-15 2013-08-07 Novartis Vaccines and Diagnostics, Inc. Compositions immunogenes contenant un antigene de l'anthrax, des microparticules de polymeres biodegradables, et un adjuvant immunologique contenant un polynucleotide
RU2461390C2 (ru) 2005-01-28 2012-09-20 Галенбио, Инк. Иммунологически активные составы
US20080138431A1 (en) * 2005-03-02 2008-06-12 James Edward Eyles Pharmaceutical Composition
EP3067048B1 (fr) 2007-12-07 2018-02-14 GlaxoSmithKline Biologicals SA Compositions d'induction des réponses immunitaires
CN101559225B (zh) * 2008-04-18 2012-07-11 北京生物制品研究所 脑膜炎球菌疫苗
CN110064049B (zh) 2012-06-21 2024-02-09 西北大学 肽缀合粒子

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239116B1 (en) * 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
CA2671261A1 (fr) * 1997-11-06 1999-05-20 Novartis Vaccines And Diagnostics S.R.L. Antigenes de neisseria
EP1047784B2 (fr) * 1998-01-14 2015-03-18 Novartis Vaccines and Diagnostics S.r.l. Antigenes du neisseria meningitidis
EP2261338A3 (fr) * 1998-05-01 2012-01-04 Novartis Vaccines and Diagnostics, Inc. Antigènes de Neisseria meningitidis et compositions
DE69930642T2 (de) * 1998-07-29 2006-12-28 Chiron Corp., Emeryville Mikropartikel mit adsorbenten oberflächen, verfahren zu ihrer herstellung und ihrer verwendung
BR9914374A (pt) * 1998-10-09 2002-09-17 Chiron Corp Sequências genÈmicas de neisseria e métodos para seu uso
CA2371994C (fr) * 1999-02-26 2010-09-28 Guido Grandi Developpement de l'activite bactericide des antigenes de neisseria a l'aide d'oligonucleotides a motifs cg
EP1156781B1 (fr) * 1999-02-26 2005-06-08 Chiron Corporation Microemulsions avec des macromolecules adsorbees et microparticules
WO2000066741A2 (fr) * 1999-04-30 2000-11-09 Chiron S.P.A. Antigenes de neisseria conserves
NZ521531A (en) * 2000-02-28 2005-12-23 Chiron S Heterologous expression of neisserial proteins

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
O'HAGAN D T ET AL: "POLY(LACTIDE-CO-GLYCOLIDE) MICROPARTICLES FOR THE DEVELOPMENT OF SINGLE-DOSE CONTROLLED-RELEASE VACCINES", ADVANCED DRUG DELIVERY REVIEWS, AMSTERDAM, NL, vol. 32, 1998, pages 225 - 246, XP000944990, ISSN: 0169-409X *
SINGH M ET AL: "ADVANCES IN VACCINE ADJUVANTS", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 17, no. 11, November 1999 (1999-11-01), pages 1075 - 1081, XP000941305, ISSN: 1087-0156 *
SINGH M ET AL: "Cationic microparticles are an effective delivery system for immunie stimulatory CpG DNA", PHARMACEUTICAL RESEARCH, NEW YORK, NY, US, vol. 18, no. 10, October 2001 (2001-10-01), pages 1476 - 1479, XP002976979, ISSN: 0724-8741 *

Also Published As

Publication number Publication date
JP4522699B2 (ja) 2010-08-11
CA2462646A1 (fr) 2003-04-10
AU2002334844B2 (en) 2007-08-02
JP2005526697A (ja) 2005-09-08
EP1438323A2 (fr) 2004-07-21
CN100354297C (zh) 2007-12-12
CN1599746A (zh) 2005-03-23
BR0213119A (pt) 2004-12-28
CA2462646C (fr) 2013-02-12
WO2003028661A2 (fr) 2003-04-10
NZ532274A (en) 2006-02-24
AU2002334844B8 (en) 2003-04-14
WO2003028661A3 (fr) 2003-10-09

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Legal Events

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Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20070704

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 39/385 20060101ALI20070628BHEP

Ipc: A61K 39/095 20060101ALI20070628BHEP

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Effective date: 20101020

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