EP1482922A4 - Mittel für die corneale oder intrastromale verabreichung zur behandlung oder prävention von erkrankungen des auges - Google Patents

Mittel für die corneale oder intrastromale verabreichung zur behandlung oder prävention von erkrankungen des auges

Info

Publication number
EP1482922A4
EP1482922A4 EP03711552A EP03711552A EP1482922A4 EP 1482922 A4 EP1482922 A4 EP 1482922A4 EP 03711552 A EP03711552 A EP 03711552A EP 03711552 A EP03711552 A EP 03711552A EP 1482922 A4 EP1482922 A4 EP 1482922A4
Authority
EP
European Patent Office
Prior art keywords
corneal
treat
eye
agents
prevent disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03711552A
Other languages
English (en)
French (fr)
Other versions
EP1482922A1 (de
Inventor
Vicken Karageozian
David Castillejos
John Park
Gabriel Arthuro Carpio Aragon
Jose Luis Gutierres Flores
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vitreo Retinal Technologies Inc
Original Assignee
Vitreo Retinal Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitreo Retinal Technologies Inc filed Critical Vitreo Retinal Technologies Inc
Publication of EP1482922A1 publication Critical patent/EP1482922A1/de
Publication of EP1482922A4 publication Critical patent/EP1482922A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
EP03711552A 2002-03-14 2003-03-14 Mittel für die corneale oder intrastromale verabreichung zur behandlung oder prävention von erkrankungen des auges Withdrawn EP1482922A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36397902P 2002-03-14 2002-03-14
US363979P 2002-03-14
PCT/US2003/007700 WO2003077898A1 (en) 2002-03-14 2003-03-14 Agents for corneal or intrastromal administration to treat or prevent disorders of the eye

Publications (2)

Publication Number Publication Date
EP1482922A1 EP1482922A1 (de) 2004-12-08
EP1482922A4 true EP1482922A4 (de) 2005-06-08

Family

ID=28041849

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03711552A Withdrawn EP1482922A4 (de) 2002-03-14 2003-03-14 Mittel für die corneale oder intrastromale verabreichung zur behandlung oder prävention von erkrankungen des auges

Country Status (10)

Country Link
EP (1) EP1482922A4 (de)
JP (1) JP2005522464A (de)
KR (1) KR20040094793A (de)
CN (1) CN1642536A (de)
AU (2) AU2003213858A1 (de)
BR (1) BR0308403A (de)
CA (1) CA2478965A1 (de)
MX (1) MXPA04008776A (de)
RU (1) RU2363459C2 (de)
WO (1) WO2003077898A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030199574A1 (en) 2000-03-02 2003-10-23 Vitreo-Retinal Technologies, Inc. Treatment of ophthalmic disorders using urea and urea derivatives
CN101231121B (zh) * 2007-01-24 2012-06-13 泰州乐金电子冷机有限公司 冰箱用托盘拉出装置
CN102859344A (zh) * 2010-03-12 2013-01-02 独立行政法人理化学研究所 用于生物材料的澄清试剂和其用途
RU2442609C1 (ru) * 2010-11-12 2012-02-20 Озеров Александр Александрович Средство для ухода за мягкими и жесткими контактными линзами
EP2711682B1 (de) 2011-05-20 2019-07-10 Riken Klärungsreagens für biologische materialien und verwendung davon
WO2015022883A1 (ja) 2013-08-14 2015-02-19 独立行政法人理化学研究所 光透過性に優れた生物材料を調製するための組成物およびその利用
DE102013110608A1 (de) * 2013-09-26 2015-03-26 Florian Lang Substanz zur Hemmung von Gewebskalzifizierung, Gewebsfibrosierung und altersassoziierten Erkrankungen
CN110237238A (zh) * 2019-08-02 2019-09-17 山东省眼科研究所 Manf在促进角膜损伤修复中的应用
US12350250B2 (en) 2022-04-01 2025-07-08 The Regent Of The University Of Colorado, A Body Corporate Aggrelytes for treating ocular conditions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000051620A1 (en) * 1999-03-02 2000-09-08 Vitreo-Retinal Technologies, Inc. Agents for intravitreal administration to treat or prevent disorders of the eye
WO2003068166A2 (en) * 2002-02-13 2003-08-21 Vitreo-Retinal Technologies, Inc. Treatment of ophthalmic disorders using urea and urea derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2094031C1 (ru) * 1992-04-09 1997-10-27 Малое государственное предприятие "Научно-экспериментальное производство" Способ профилактики новообразованных сосудов роговицы после сквозной и послойной кератопластики
US5470881A (en) * 1993-09-09 1995-11-28 West Virginia University Research Corporation Urea ophthalmic ointment and solution
RU2082434C1 (ru) * 1994-12-19 1997-06-27 Уфимский научно-исследовательский институт глазных болезней Глазная мазь

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000051620A1 (en) * 1999-03-02 2000-09-08 Vitreo-Retinal Technologies, Inc. Agents for intravitreal administration to treat or prevent disorders of the eye
WO2003068166A2 (en) * 2002-02-13 2003-08-21 Vitreo-Retinal Technologies, Inc. Treatment of ophthalmic disorders using urea and urea derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO03077898A1 *

Also Published As

Publication number Publication date
AU2009201897A1 (en) 2009-06-04
AU2009201897B2 (en) 2011-09-15
EP1482922A1 (de) 2004-12-08
WO2003077898A1 (en) 2003-09-25
RU2363459C2 (ru) 2009-08-10
RU2004129761A (ru) 2005-06-10
CN1642536A (zh) 2005-07-20
AU2003213858A1 (en) 2003-09-29
JP2005522464A (ja) 2005-07-28
CA2478965A1 (en) 2003-09-25
MXPA04008776A (es) 2005-04-19
KR20040094793A (ko) 2004-11-10
BR0308403A (pt) 2005-01-18

Similar Documents

Publication Publication Date Title
EP1592435A4 (de) Augenformulierung zur vorbeugung und behandlung von augenleiden
GB0404693D0 (en) Pharmaceutical preparations for the treatment of ocular surface and other disorders
SI1660057T1 (sl) Kombinirana terapija za zdravljenje okularnih neovaskularnih nepravilnosti
FI9630U1 (fi) Järjestelmä potilaan silmän verkkokalvon hoitamiseksi laserilla
IL230242A (en) Retinal history and methods of using them to treat visual irregularities
ZA200802872B (en) Combination therapy comprising substituted oxazolidinones for the prevention and treatment of cerebral circulatory disorders
WO2008029276A3 (en) Compositions and methods for the treatment of ophthalmic disease
PL367959A1 (en) Integrin inhibitors for the treatment of eye diseases
EP1631297A4 (de) Behandlung von immunvermittelten erkrankungen mit aktiven vitamin d verbindungen allein oder in kombination mit anderen therapeutika
GB2402674B (en) Compositions and methods for the treatment of glaucoma or ocular hypertension
IL173351A0 (en) Therapy of ocular disorders
WO2004012762A3 (en) Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels
WO2002079169A8 (en) Cyano-substituted dihydropyrimidine compounds and their use to treat diseases
DK1614419T3 (da) Midler til forebyggelse/behandling af retinale nervesygdomme, indeholdende alkyletherderivater eller salte deraf
EP1482922A4 (de) Mittel für die corneale oder intrastromale verabreichung zur behandlung oder prävention von erkrankungen des auges
PL378210A1 (pl) Zastosowanie steroidów do leczenia osób cierpiących z powodu zaburzeń gałki ocznej
AU2003291253A1 (en) Scleral implants for treatment of eye disorders
MX2007004030A (es) Analogos de poliamina como agentes terapeuticos para enfermedades oculares.
CA2414586A1 (en) Agent for therapeutic treatment of optic nerve diseases and the like
PT1534296E (pt) UTILIZAÇÃO DE CILOBRADINA OU DOS SEUS SAIS FARMACEUTICAMENTE ACEITÁVEIS PARA O TRATAMENTO OU PREVENÇÃO DA INSUFICIjNCIA CARDÍACA
IL163938A0 (en) Agents for corneal or intrastromal administration to treat or prevent disorders of the eye
PL368565A1 (en) Use of compounds for treating conditions resulting from injury to the corneal nerve after lasik and other ocular surgeries or trauma
WO2007117272A3 (en) Methods for treatment of hemorrhagic shock and related disorders
WO2004002399A3 (en) Use of gaba-c receptor antagonists for the treatment of myopia
GB0317241D0 (en) Therapeutic agents for the treatment of bone disorders

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20040901

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

A4 Supplementary search report drawn up and despatched

Effective date: 20050421

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61P 27/06 B

Ipc: 7A 61K 31/40 B

Ipc: 7A 61K 31/17 A

17Q First examination report despatched

Effective date: 20060119

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

RTI1 Title (correction)

Free format text: AGENTS FOR CORNEAL ADMINISTRATION TO TREAT OR PREVENT DISORDERS OF THE EYE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20100310