EP1670486A4 - Behandlung eines zustands in einem säugetier mit verabreichung von aminozucker und verwendungen davon - Google Patents

Behandlung eines zustands in einem säugetier mit verabreichung von aminozucker und verwendungen davon

Info

Publication number
EP1670486A4
EP1670486A4 EP04789289A EP04789289A EP1670486A4 EP 1670486 A4 EP1670486 A4 EP 1670486A4 EP 04789289 A EP04789289 A EP 04789289A EP 04789289 A EP04789289 A EP 04789289A EP 1670486 A4 EP1670486 A4 EP 1670486A4
Authority
EP
European Patent Office
Prior art keywords
amin
mammal
disorder
administering
sugar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04789289A
Other languages
English (en)
French (fr)
Other versions
EP1670486A1 (de
Inventor
Youe-Kong Shue
Franklin W Okumu
Alexander R Shikhman
Martin Lotz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Optimer Pharmaceuticals LLC
Original Assignee
Scripps Research Institute
Optimer Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute, Optimer Pharmaceuticals LLC filed Critical Scripps Research Institute
Publication of EP1670486A1 publication Critical patent/EP1670486A1/de
Publication of EP1670486A4 publication Critical patent/EP1670486A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
EP04789289A 2003-10-01 2004-09-30 Behandlung eines zustands in einem säugetier mit verabreichung von aminozucker und verwendungen davon Withdrawn EP1670486A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50771603P 2003-10-01 2003-10-01
PCT/US2004/032048 WO2005034961A1 (en) 2003-10-01 2004-09-30 Treatment of a condition in a mammal with adminisration of aminosugar and uses thereof

Publications (2)

Publication Number Publication Date
EP1670486A1 EP1670486A1 (de) 2006-06-21
EP1670486A4 true EP1670486A4 (de) 2009-04-01

Family

ID=34434891

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04789289A Withdrawn EP1670486A4 (de) 2003-10-01 2004-09-30 Behandlung eines zustands in einem säugetier mit verabreichung von aminozucker und verwendungen davon

Country Status (5)

Country Link
EP (1) EP1670486A4 (de)
JP (1) JP2007507516A (de)
CN (1) CN1909911A (de)
CA (1) CA2540586A1 (de)
WO (1) WO2005034961A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120225033A1 (en) * 2010-11-24 2012-09-06 Durect Corporation Biodegradable Drug Delivery Composition
CA2553866A1 (en) * 2004-01-20 2005-08-11 The Scripps Research Institute Treatment of degenerative cartilage conditions in a mammal with glycosi dase inhibitors
CN102159218B (zh) * 2008-07-18 2015-12-02 杰尼斯Ehf公司 用于医学用途的新型几丁低聚物组合物
KR101098581B1 (ko) 2009-01-09 2011-12-26 서울대학교산학협력단 Ａｂｈ 항원을 이용한 염증질환 개선용 조성물
CN102614111B (zh) * 2012-04-05 2013-11-06 苏州豫源生物医药有限公司 氨基葡萄糖的凝胶剂及其制备方法
CN105884720A (zh) * 2016-04-23 2016-08-24 陈斌 一种盐酸丁螺环酮的药物组合物及其医药用途
WO2020104833A1 (en) * 2018-11-19 2020-05-28 4P-Pharma Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production
CN112169713A (zh) * 2020-09-09 2021-01-05 江南大学 一种n-烷基乳糖胺表面活性剂小分子醇凝胶及其制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0379753A1 (de) * 1989-01-26 1990-08-01 Steigerwald Arzneimittelwerk Gmbh N-Acetylglucosamin-Zubereitungen zur buccalen Anwendung
WO1997021434A1 (en) * 1995-12-11 1997-06-19 Inholtra, Inc. Dietary regimen of nutritional supplements for relief of symptoms of arthritis
WO1998025631A1 (en) * 1996-12-13 1998-06-18 Lescarden, Inc. Treatment of osteoarthritis by administering poly-n-acetyl-d-glucosamine
US6346519B1 (en) * 1998-09-09 2002-02-12 Advanced Medical Instruments Method and composition for treating arthritis
US6378527B1 (en) * 1998-04-08 2002-04-30 Chondros, Inc. Cell-culture and polymer constructs
WO2002078445A1 (en) * 2001-03-29 2002-10-10 The Scripps Research Institute Formulations comprising entrapped active ingredients and uses thereof
WO2003026677A1 (en) * 2001-09-26 2003-04-03 Primex Ehf. Pharmaceutical composition comprising chito-oligomers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPM666894A0 (en) * 1994-07-07 1994-07-28 University Of Melbourne, The Diagnostic methods and compositions
US5840715A (en) * 1995-12-11 1998-11-24 Inholtra Investment Holdings & Trading, N.V. Dietary regimen of nutritional supplements for relief of symptoms of arthritis
US6514983B1 (en) * 1997-09-03 2003-02-04 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
US6514522B2 (en) * 1998-04-08 2003-02-04 Chondros, Inc. Polymer constructs
CA2332279A1 (en) * 1998-05-15 1999-11-25 Jia-He Li Carboxamide compounds, compositions, and methods for inhibiting parp activity
US6506785B2 (en) * 1998-05-22 2003-01-14 Pfizer, Inc. Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives
US6656925B2 (en) * 1998-09-09 2003-12-02 Advanced Medical Instruments Composition and method of treating arthritis
US6662805B2 (en) * 1999-03-24 2003-12-16 The Johns Hopkins University Method for composite cell-based implants
MXPA01011542A (es) * 2001-11-13 2003-05-22 Alcon Inc Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel.
JP2003225093A (ja) * 2001-11-30 2003-08-12 Sumitomo Pharmaceut Co Ltd 軟骨障害マーカー及びその利用
OA12731A (en) * 2001-11-30 2006-06-28 Pfizer Controlled release polymeric compositions of bone growth promoting compounds.

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0379753A1 (de) * 1989-01-26 1990-08-01 Steigerwald Arzneimittelwerk Gmbh N-Acetylglucosamin-Zubereitungen zur buccalen Anwendung
WO1997021434A1 (en) * 1995-12-11 1997-06-19 Inholtra, Inc. Dietary regimen of nutritional supplements for relief of symptoms of arthritis
WO1998025631A1 (en) * 1996-12-13 1998-06-18 Lescarden, Inc. Treatment of osteoarthritis by administering poly-n-acetyl-d-glucosamine
US6117851A (en) * 1996-12-13 2000-09-12 Lescarden Inc. Treatment of osteoarthritis by administering poly-N-acetyl-D-glucosamine
US6378527B1 (en) * 1998-04-08 2002-04-30 Chondros, Inc. Cell-culture and polymer constructs
US6346519B1 (en) * 1998-09-09 2002-02-12 Advanced Medical Instruments Method and composition for treating arthritis
WO2002078445A1 (en) * 2001-03-29 2002-10-10 The Scripps Research Institute Formulations comprising entrapped active ingredients and uses thereof
WO2003026677A1 (en) * 2001-09-26 2003-04-03 Primex Ehf. Pharmaceutical composition comprising chito-oligomers

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
GREILING H ET AL: "DIE HEMMUNG LYSOSOMALER ENZYME DURCH EIN GLYKOSAMINOGLYKANPOLYSULFAT ZUR THERAPIE CHRONISCHER GELENKERKRANKUNGEN MIT ANTIDEGENERATIV WIRKSAMEN VERDINGUNGEN; EIN BEITRAG ZUR BIOCHEMIE", ARZNEIMITTEL FORSCHUNG. DRUG RESEARCH, ECV EDITIO CANTOR VERLAG, AULENDORF, DE, vol. 23, no. 4, 1 January 1973 (1973-01-01), pages 593 - 597, XP000990352, ISSN: 0004-4172 *
LIU J ET AL: "Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis", CHEMISTRY AND BIOLOGY, CURRENT BIOLOGY, LONDON, GB, vol. 8, no. 7, 1 January 2001 (2001-01-01), pages 701 - 711, XP002444424, ISSN: 1074-5521 *
See also references of WO2005034961A1 *
SHIKHMAN A R ET AL: "N-acetylglucosamine prevents IL-1 beta-mediated activation of human chondrocytes", JOURNAL OF IMMUNOLOGY, AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 166, no. 8, 15 April 2001 (2001-04-15), pages 5155 - 5160, XP002505181, ISSN: 0022-1767 *

Also Published As

Publication number Publication date
EP1670486A1 (de) 2006-06-21
CA2540586A1 (en) 2005-04-21
WO2005034961A1 (en) 2005-04-21
JP2007507516A (ja) 2007-03-29
CN1909911A (zh) 2007-02-07

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: OPTIMER PHARMACEUTICALS

Owner name: THE SCRIPPS RESEARCH INSTITUTE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SHUE, YOUE-KONG

Inventor name: LOTZ, MARTIN

Inventor name: OKUMU, FRANKLIN, W.

Inventor name: SHIKHMAN, ALEXANDER, R.

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: THE SCRIPPS RESEARCH INSTITUTE

Owner name: OPTIMER PHARMACEUTICALS, INC.

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A4 Supplementary search report drawn up and despatched

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