EP1748078A3 - Kombinationsoligomere betreffende Verfahren, Kits und Zusammensetzungen - Google Patents

Kombinationsoligomere betreffende Verfahren, Kits und Zusammensetzungen Download PDF

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Publication number
EP1748078A3
EP1748078A3 EP06023675A EP06023675A EP1748078A3 EP 1748078 A3 EP1748078 A3 EP 1748078A3 EP 06023675 A EP06023675 A EP 06023675A EP 06023675 A EP06023675 A EP 06023675A EP 1748078 A3 EP1748078 A3 EP 1748078A3
Authority
EP
European Patent Office
Prior art keywords
kits
compositions
combination oligomers
methods
pna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP06023675A
Other languages
English (en)
French (fr)
Other versions
EP1748078B1 (de
EP1748078A2 (de
Inventor
James M. Coull
Mark J. Fiandaca
Mark D. Kristjanson
Jens J. Hyldig-Nielsen
Theresa M. Creasey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technologies Corp
Original Assignee
Boston Probes Inc
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Filing date
Publication date
Application filed by Boston Probes Inc filed Critical Boston Probes Inc
Publication of EP1748078A2 publication Critical patent/EP1748078A2/de
Publication of EP1748078A3 publication Critical patent/EP1748078A3/de
Application granted granted Critical
Publication of EP1748078B1 publication Critical patent/EP1748078B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B20/00—Methods specially adapted for identifying library members
    • C40B20/04—Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members, e.g. decoding processes
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Sealing Material Composition (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Electric Connection Of Electric Components To Printed Circuits (AREA)
  • Prostheses (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
EP06023675A 2001-03-09 2002-03-09 Kombinationsoligomere betreffende Verfahren, Kits und Zusammensetzungen Expired - Lifetime EP1748078B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27454701P 2001-03-09 2001-03-09
EP02719163A EP1412517B1 (de) 2001-03-09 2002-03-09 Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP02719163.4 Division 2002-03-09
EP02719163A Division EP1412517B1 (de) 2001-03-09 2002-03-09 Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen

Publications (3)

Publication Number Publication Date
EP1748078A2 EP1748078A2 (de) 2007-01-31
EP1748078A3 true EP1748078A3 (de) 2007-02-28
EP1748078B1 EP1748078B1 (de) 2011-01-19

Family

ID=23048654

Family Applications (2)

Application Number Title Priority Date Filing Date
EP02719163A Expired - Lifetime EP1412517B1 (de) 2001-03-09 2002-03-09 Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen
EP06023675A Expired - Lifetime EP1748078B1 (de) 2001-03-09 2002-03-09 Kombinationsoligomere betreffende Verfahren, Kits und Zusammensetzungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP02719163A Expired - Lifetime EP1412517B1 (de) 2001-03-09 2002-03-09 Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen

Country Status (9)

Country Link
US (9) US7256275B2 (de)
EP (2) EP1412517B1 (de)
JP (2) JP4408628B2 (de)
AT (2) ATE496139T1 (de)
AU (1) AU2002250262B9 (de)
CA (1) CA2439750A1 (de)
DE (2) DE60216468T2 (de)
DK (1) DK1412517T3 (de)
WO (1) WO2002072865A2 (de)

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DE60216468T2 (de) * 2001-03-09 2007-09-27 Boston Probes, Inc., Bedford Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen
EP1575990B1 (de) 2002-09-08 2009-11-18 Applera Corporation Festphasengebundene PNA-Dimere und deren Synthese
WO2004074447A2 (en) * 2003-02-18 2004-09-02 Applera Corporation Compositions and methods for multiplex analysis of polynucleotides
EP1674581A1 (de) * 2004-12-21 2006-06-28 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Doppelsonden und ihre Verwendung zum Nachweis von SNPS
US7892737B2 (en) * 2005-06-30 2011-02-22 Life Technologies Corporation Compositions, kits and methods pertaining to stability modulation of PNA oligomer/nucleic acid complexes
GB2433591A (en) * 2005-12-20 2007-06-27 Sharp Kk Method for functionalising a hydrophobic substrate
GB2433505A (en) * 2005-12-20 2007-06-27 Sharp Kk Capture agents for binding a ligand
GB2433506A (en) * 2005-12-20 2007-06-27 Sharp Kk A method of producing a multimeric capture agent
US9677123B2 (en) * 2006-03-15 2017-06-13 Siemens Healthcare Diagnostics Inc. Degenerate nucleobase analogs
CN101421420B (zh) * 2006-08-08 2015-03-11 爱科来株式会社 突变的检测方法及用于该方法的试剂盒
WO2008039367A1 (en) * 2006-09-22 2008-04-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Synthesis of trans-tert-butyl-2-aminocyclopentylcarbamate
GB0718255D0 (en) * 2007-09-19 2007-10-31 Univ Edinburgh Nucleobase characterisation
WO2010031002A1 (en) * 2008-09-14 2010-03-18 Incitor, Llc Nanoscale molecule synthesis
EP2553123B1 (de) * 2010-03-26 2016-08-24 Integrated DNA Technologies, Inc. Verfahren zur verstärkung einer nukleinsäurehybridisierung
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
EP2614149B1 (de) 2010-09-07 2015-04-08 Integrated Dna Technologies, Inc. Modifizierungen für antisense-verbindungen
EP2691543B1 (de) * 2011-03-29 2017-11-01 Seegene, Inc. Erkennung von zielnukleinsäuresequenzen durch pto-spaltung und verlängerungsabhängige spaltung
WO2013103146A1 (ja) * 2012-01-07 2013-07-11 株式会社ボナック アミノ酸骨格を有する一本鎖核酸分子
CA2864523C (en) * 2012-03-05 2019-02-05 Seegene, Inc. Detection of nucleotide variation on target nucleic acid sequence by pto cleavage and extension assay
CN109810977A (zh) 2012-05-26 2019-05-28 株式会社博纳克 具有递送功能的基因表达调控用单链核酸分子
WO2014021680A1 (ko) * 2012-08-02 2014-02-06 (주)바이오니아 신규 아조화합물, 이의 이용 및 이의제조방법
GB201316644D0 (en) * 2013-09-19 2013-11-06 Kymab Ltd Expression vector production & High-Throughput cell screening
US10612020B2 (en) 2013-12-26 2020-04-07 Tokyo Medical University Artificial mimic miRNA for controlling gene expression, and use of same
WO2015099187A1 (ja) 2013-12-27 2015-07-02 株式会社ボナック 遺伝子発現制御のための人工マッチ型ｍｉＲＮＡおよびその用途
US11027023B2 (en) 2014-12-27 2021-06-08 Bonac Corporation Natural type miRNA for controlling gene expression, and use of same
US11142769B2 (en) 2015-03-27 2021-10-12 Bonac Corporation Single-stranded nucleic acid molecule having delivery function and gene expression regulating ability
EP3416976A2 (de) 2016-02-16 2018-12-26 Yale University Zusammensetzungen zur verbesserung von gezielter geneditierung und verfahren zur verwendung davon
US20200113821A1 (en) 2017-04-04 2020-04-16 Yale University Compositions and methods for in utero delivery
KR102403904B1 (ko) * 2019-12-24 2022-06-02 주식회사 시선바이오머티리얼스 용액공정상 pna 올리고머의 제조방법
CN116438456A (zh) * 2020-09-11 2023-07-14 格里姆普斯生物股份有限公司 用于疾病检测/诊断、分期、监测和治疗的离体蛋白酶活性检测
CN113322523B (zh) * 2021-06-17 2024-03-19 翌圣生物科技(上海)股份有限公司 Rna快速建库方法及其应用

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Also Published As

Publication number Publication date
US7605253B2 (en) 2009-10-20
EP1412517A2 (de) 2004-04-28
US20080085837A1 (en) 2008-04-10
CA2439750A1 (en) 2002-09-19
AU2002250262B2 (en) 2006-10-26
EP1748078B1 (de) 2011-01-19
WO2002072865A2 (en) 2002-09-19
US20070105145A1 (en) 2007-05-10
EP1412517B1 (de) 2006-11-29
US20080269074A1 (en) 2008-10-30
AU2002250262B9 (en) 2006-11-30
DE60216468T2 (de) 2007-09-27
WO2002072865A3 (en) 2003-11-27
DE60239020D1 (de) 2011-03-03
US7256275B2 (en) 2007-08-14
US20030077608A1 (en) 2003-04-24
EP1748078A2 (de) 2007-01-31
US20080220987A1 (en) 2008-09-11
US20080125332A1 (en) 2008-05-29
JP2004524032A (ja) 2004-08-12
US7851155B2 (en) 2010-12-14
EP1412517A4 (de) 2004-07-07
US20080206747A1 (en) 2008-08-28
JP4408628B2 (ja) 2010-02-03
US7674585B2 (en) 2010-03-09
US7638279B2 (en) 2009-12-29
US7745126B2 (en) 2010-06-29
DE60216468D1 (de) 2007-01-11
DK1412517T3 (da) 2007-03-05
ATE346950T1 (de) 2006-12-15
US7884053B2 (en) 2011-02-08
US20090163381A1 (en) 2009-06-25
US7566420B1 (en) 2009-07-28
JP2007209346A (ja) 2007-08-23
ATE496139T1 (de) 2011-02-15

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