EP1888106A4 - Compositions et méthodes de traitement d'états associés à la signalisation de l'éphrine au moyen de cuprédoxines - Google Patents

Compositions et méthodes de traitement d'états associés à la signalisation de l'éphrine au moyen de cuprédoxines

Info

Publication number
EP1888106A4
EP1888106A4 EP06813192A EP06813192A EP1888106A4 EP 1888106 A4 EP1888106 A4 EP 1888106A4 EP 06813192 A EP06813192 A EP 06813192A EP 06813192 A EP06813192 A EP 06813192A EP 1888106 A4 EP1888106 A4 EP 1888106A4
Authority
EP
European Patent Office
Prior art keywords
cupredoxines
compositions
treating
methods
ephrin signaling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06813192A
Other languages
German (de)
English (en)
Other versions
EP1888106A2 (fr
Inventor
Ananda Chakrabarty
Gupta Tapas Das
Tohru Yamada
Anita Chaudhari
Arsenio Fialho
Yonghua Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois at Urbana Champaign
University of Illinois System
Original Assignee
University of Illinois at Urbana Champaign
University of Illinois System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/244,105 external-priority patent/US7691383B2/en
Application filed by University of Illinois at Urbana Champaign, University of Illinois System filed Critical University of Illinois at Urbana Champaign
Publication of EP1888106A2 publication Critical patent/EP1888106A2/fr
Publication of EP1888106A4 publication Critical patent/EP1888106A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP06813192A 2005-05-20 2006-05-19 Compositions et méthodes de traitement d'états associés à la signalisation de l'éphrine au moyen de cuprédoxines Withdrawn EP1888106A4 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68281205P 2005-05-20 2005-05-20
US11/244,105 US7691383B2 (en) 2004-10-07 2005-10-06 Cupredoxin derived transport agents and methods of use thereof
US76474906P 2006-02-03 2006-02-03
PCT/US2006/019684 WO2007018671A2 (fr) 2005-05-20 2006-05-19 Compositions et methodes de traitement d'etats associes a la signalisation de l'ephrine au moyen de cupredoxines

Publications (2)

Publication Number Publication Date
EP1888106A2 EP1888106A2 (fr) 2008-02-20
EP1888106A4 true EP1888106A4 (fr) 2009-01-14

Family

ID=37727776

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06813192A Withdrawn EP1888106A4 (fr) 2005-05-20 2006-05-19 Compositions et méthodes de traitement d'états associés à la signalisation de l'éphrine au moyen de cuprédoxines

Country Status (10)

Country Link
EP (1) EP1888106A4 (fr)
JP (1) JP2008539795A (fr)
KR (1) KR20080040631A (fr)
AU (1) AU2006277009A1 (fr)
BR (1) BRPI0612424A2 (fr)
CA (1) CA2608512A1 (fr)
IL (1) IL187138A0 (fr)
MX (1) MX2007014598A (fr)
NO (1) NO20076391L (fr)
WO (1) WO2007018671A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9096663B2 (en) 2001-02-15 2015-08-04 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating conditions related to ephrin signaling with cupredoxins and mutants thereof
US7381701B2 (en) 2001-02-15 2008-06-03 The Borad Of Trustees Of The University Of Illinois Compositions and methods for treating conditions related to ephrin signaling with cupredoxins
US7556810B2 (en) 2005-07-19 2009-07-07 The Board Of Trustees Of The University Of Ilinois Compositions and methods to control angiogenesis with cupredoxins
UA97466C2 (ru) 2004-10-07 2012-02-27 Ананда Чакрабарти Транспортирующие соединения - производные купредоксина и способы их применения
MX2008000993A (es) * 2005-07-19 2008-03-19 Univ Illinois Composiciones y metodos para controlar la angiogenesis con cupredoxinas.
AU2006269879A1 (en) 2005-07-19 2007-01-25 The Board Of Trustees Of The University Of Illinois Transport agents for crossing the blood-brain barrier and into brain cancer cells, and methods of use thereof
JP2010503409A (ja) * 2006-09-14 2010-02-04 ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ クプレドキシンによって癌を予防する組成物および方法
EP2117573A4 (fr) * 2007-01-11 2011-02-16 Univ Illinois Compositions et méthodes permettant de traiter des affections associées à la signalisation de l'éphrine avec des cuprexodines et des mutants de celles-ci
HRP20170407T1 (hr) 2007-08-30 2017-05-05 Daiichi Sankyo Company, Limited Anti-epha2 anitijelo
KR101102829B1 (ko) * 2008-09-12 2012-01-05 재단법인 제주테크노파크 구멍갈파래 추출물과 그것의 항염증제로서의 용도
CN110090295B (zh) * 2018-01-29 2022-12-23 武汉康理通科技有限公司 Ephrin-B1在制备治疗炎症性肠病的药物中的用途
WO2023205752A2 (fr) * 2022-04-22 2023-10-26 University Of Miami Peptides mimétiques de ligand d'éphrine pour le traitement de maladies neurodégénératives
WO2025207820A2 (fr) * 2024-03-27 2025-10-02 Mediar Therapeutics, Inc. Anticorps anti-éphrine b2 et méthodes d'utilisation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002076380A2 (fr) * 2001-02-15 2002-10-03 The Board Of Trustees Of The University Of Illinois Facteurs cytotoxiques destines a moduler la mort cellulaire
WO2005018662A1 (fr) * 2003-08-15 2005-03-03 Board Of Trustees Of The University Of Illinois Utilisation de polypeptides de la famille des cupredoxines dans la therapie du cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002076380A2 (fr) * 2001-02-15 2002-10-03 The Board Of Trustees Of The University Of Illinois Facteurs cytotoxiques destines a moduler la mort cellulaire
US20060040269A1 (en) * 2001-02-15 2006-02-23 Chakrabarty Ananda M Cytotoxic factors for modulating cell death
WO2005018662A1 (fr) * 2003-08-15 2005-03-03 Board Of Trustees Of The University Of Illinois Utilisation de polypeptides de la famille des cupredoxines dans la therapie du cancer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HIMANEN J-P ET AL: "Eph signaling: a structural view", TRENDS IN NEUROSCIENCE, ELSEVIER, AMSTERDAM, NL, vol. 26, no. 1, 1 January 2003 (2003-01-01), pages 46 - 51, XP004398871, ISSN: 0166-2236 *
TOTH JOSEPH ET AL: "Crystal structure of an ephrin ectodomain", DEVELOPMENTAL CELL, vol. 1, no. 1, July 2001 (2001-07-01), pages 83 - 92, XP002505155, ISSN: 1534-5807 *
YAMADA TOHRU ET AL: "Bacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 99, no. 22, 29 October 2002 (2002-10-29), pages 14098 - 14103, XP002486971, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
BRPI0612424A2 (pt) 2009-01-27
JP2008539795A (ja) 2008-11-20
KR20080040631A (ko) 2008-05-08
MX2007014598A (es) 2008-02-07
AU2006277009A1 (en) 2007-02-15
WO2007018671A2 (fr) 2007-02-15
IL187138A0 (en) 2008-02-09
EP1888106A2 (fr) 2008-02-20
CA2608512A1 (fr) 2007-02-15
WO2007018671A3 (fr) 2007-11-22
NO20076391L (no) 2008-02-15

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: ZHU, YONGHUA

Inventor name: FIALHO, ARSENIO

Inventor name: CHAUDHARI, ANITA

Inventor name: YAMADA, TOHRU

Inventor name: DAS GUPTA, TAPAS

Inventor name: CHAKRABARTY, ANANDA

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 35/00 20060101ALI20081202BHEP

Ipc: A61P 31/18 20060101ALI20081202BHEP

Ipc: A61K 38/16 20060101ALI20081202BHEP

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