EP1895849A4 - Procedes pour le traitement de maladies oculaires induites par les proteines beta-amyloidiennes - Google Patents
Procedes pour le traitement de maladies oculaires induites par les proteines beta-amyloidiennesInfo
- Publication number
- EP1895849A4 EP1895849A4 EP06773171A EP06773171A EP1895849A4 EP 1895849 A4 EP1895849 A4 EP 1895849A4 EP 06773171 A EP06773171 A EP 06773171A EP 06773171 A EP06773171 A EP 06773171A EP 1895849 A4 EP1895849 A4 EP 1895849A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- beta
- methods
- ocular diseases
- treating ocular
- diseases induced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69081205P | 2005-06-15 | 2005-06-15 | |
| US73979705P | 2005-11-23 | 2005-11-23 | |
| US11/287,080 US7728043B2 (en) | 1999-10-22 | 2005-11-23 | Methods for treatment of beta-amyloid protein-induced ocular disease |
| PCT/US2006/023197 WO2006138399A1 (fr) | 2005-06-15 | 2006-06-14 | Procedes pour le traitement de maladies oculaires induites par les proteines beta-amyloidiennes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1895849A1 EP1895849A1 (fr) | 2008-03-12 |
| EP1895849A4 true EP1895849A4 (fr) | 2009-11-11 |
Family
ID=37570771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP06773171A Withdrawn EP1895849A4 (fr) | 2005-06-15 | 2006-06-14 | Procedes pour le traitement de maladies oculaires induites par les proteines beta-amyloidiennes |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1895849A4 (fr) |
| CA (1) | CA2611490A1 (fr) |
| WO (1) | WO2006138399A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2950804B1 (fr) * | 2009-10-01 | 2011-12-23 | Oreal | Composition, utilisation et procede de conservation |
| US9365486B2 (en) * | 2014-07-01 | 2016-06-14 | Muhammed Majeed | Synthesis of calebin-A and its biologically active analogs |
| CN110229056B (zh) * | 2019-06-21 | 2022-11-08 | 天津科技大学 | 一种新型姜黄素类似物及其制备方法和应用 |
| JP2024528336A (ja) * | 2021-07-08 | 2024-07-29 | ニューラクル サイエンス カンパニー リミテッド | 抑制剤及びその用途 |
| JP2024542896A (ja) * | 2021-11-23 | 2024-11-19 | ニューラクル サイエンス カンパニー リミテッド | Lrrc4ファミリー摸倣分子及びその診断用途 |
| CN117045626A (zh) * | 2023-05-06 | 2023-11-14 | 浙江大学 | 姜酮在制备神经细胞线粒体损伤保护产品中的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001030335A2 (fr) * | 1999-10-22 | 2001-05-03 | The Board Of Trustees Of The University Of Illinois | Compositions pharmaceutiques utiles dans la prevention et le traitement d'une maladie induite par la proteine beta-amyloide |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040101578A1 (en) * | 2001-08-03 | 2004-05-27 | Min-Young Kim | Compositon containg ginkgo biloba that inhibit angiogenesis and matrix metalloprotinase |
-
2006
- 2006-06-14 EP EP06773171A patent/EP1895849A4/fr not_active Withdrawn
- 2006-06-14 CA CA002611490A patent/CA2611490A1/fr not_active Abandoned
- 2006-06-14 WO PCT/US2006/023197 patent/WO2006138399A1/fr not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001030335A2 (fr) * | 1999-10-22 | 2001-05-03 | The Board Of Trustees Of The University Of Illinois | Compositions pharmaceutiques utiles dans la prevention et le traitement d'une maladie induite par la proteine beta-amyloide |
Non-Patent Citations (12)
| Title |
|---|
| BATE C ET AL: "Ginkgolide B inhibits the neurotoxicity of prions or amyloid-[beta] 1-42", JOURNAL OF NEUROINFLAMMATION 20040511 GB, vol. 1, 11 May 2004 (2004-05-11), XP002542118, ISSN: 1742-2094 * |
| DENTCHEV T ET AL: "Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas", MOLECULAR VISION, MOLECULAR VISION, SN, ATLANTA, 1 September 2003 (2003-09-01), pages 184 - 190, XP003001744, ISSN: 1090-0535 * |
| JANCIAUSKIENE S ET AL: "Alzheimer's peptide and serine proteinase inhibitors in glaucoma and exfoliation syndrome", DOCUMENTA OPHTHALMOLOGICA 200305 NL, vol. 106, no. 3, May 2003 (2003-05-01), pages 215 - 223, XP002542123, ISSN: 0012-4486 * |
| JOHNSON L V ET AL: "The Alzheimer's Abeta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 99, no. 18, 3 September 2002 (2002-09-03), pages 11830 - 11835, XP003000979, ISSN: 0027-8424 * |
| KIM D S H L ET AL: "Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from [beta]A(1-42) insult", NEUROSCIENCE LETTERS 20010427 IE, vol. 303, no. 1, 27 April 2001 (2001-04-27), pages 57 - 61, XP002542120, ISSN: 0304-3940 * |
| KIM D S H L ET AL: "Shogaols from Zingiber officinale protect IMR32 human neuroblastoma and normal human umbilical vein endothelial cells from [beta]amyloid(25-35) insult", PLANTA MEDICA 2002 DE, vol. 68, no. 4, 2002, pages 375 - 376, XP002542122, ISSN: 0032-0943 * |
| KIM DARRICK S H L ET AL: "Side-chain length is important for shogaols in protecting neuronal cells from beta-amyloid insult.", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 8 MAR 2004, vol. 14, no. 5, 8 March 2004 (2004-03-08), pages 1287 - 1289, XP002542121, ISSN: 0960-894X * |
| MCKINNON STUART J: "Glaucoma: ocular Alzheimer's disease?", FRONTIERS IN BIOSCIENCE,, vol. 8, 1 September 2003 (2003-09-01), pages s1140 - s1156, XP009121526, ISSN: 1093-4715 * |
| ONO K ET AL: "Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro", JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, US, vol. 75, no. 6, 15 March 2004 (2004-03-15), pages 742 - 750, XP002989615, ISSN: 0360-4012 * |
| PARK, SO-YOUNG: "Discovery of natural products from turmeric and sage that protect cells against beta-amyloid insult", DISSERTATION, 1 January 2001 (2001-01-01), Avail.: UMI, Order No. DA3008089 From: Diss. Abstr. Int., B 2001, 62(3), 1400, XP009121721 * |
| See also references of WO2006138399A1 * |
| YAO Z -X ET AL: "The Ginkgo biloba extract EGb 761 rescues the PC12 neuronal cells from [beta]-amyloid-induced cell death by inhibiting the formation of [beta]-amyloid-derived diffusible neurotoxic ligands", BRAIN RESEARCH 20010119 NL, vol. 889, no. 1-2, 19 January 2001 (2001-01-19), pages 181 - 190, XP002542119, ISSN: 0006-8993 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2611490A1 (fr) | 2006-12-28 |
| EP1895849A1 (fr) | 2008-03-12 |
| WO2006138399A1 (fr) | 2006-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20080115 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
| DAX | Request for extension of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/343 20060101ALI20090828BHEP Ipc: A61K 31/352 20060101ALI20090828BHEP Ipc: A61K 31/60 20060101ALI20090828BHEP Ipc: A61K 31/05 20060101AFI20090828BHEP Ipc: A01N 65/00 20090101ALI20090828BHEP |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20090907 |
|
| 17Q | First examination report despatched |
Effective date: 20100115 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20100730 |