Classifications

• • G—PHYSICS
  • G01—MEASURING; TESTING
  • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
  • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
  • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
  • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
  • G01N33/521—Single-layer analytical elements
  • G01N33/523—Single-layer analytical elements the element being adapted for a specific analyte

Definitions

• the diazonium ion may be zwitterionic in that the counterion of the diazonium moiety is covalently bound to the ring system.
• the ring system of the diazonium ion may be substituted or unsubstituted.
• the ion may be provided by a variety of suitable diazonium salts, such as diazonium chlorides, diazonium acid sulphates, diazonium alkyl sulphates, diazonium fluoborates, diazonium benzenesulphonates, diazonium acid 1 ,5-naphthalenedisulphonates, and so forth.
• a substrate is employed.
• the substrate may be mixed with the test sample prior to application to the device 20.
• the substrate may be diffusively immobilized on the device 20 prior to application of the test sample.
• Such pre-application provides a variety of benefits, including the elimination of the need for a subsequent user to handle and mix the reagents with the test sample or a diluent. This is particularly useful in point-of- care applications when the user is not generally a trained lab technician or medical professional.
• the substrate may be disposed downstream from the sample application zone 24. In this manner, the test sample is capable of mixing with the substrate upon application. Alternatively, the substrate may be positioned upstream from the sample application zone 24. For instance, a diluent may be employed to induce mixing between the substrate and test sample.

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• Health & Medical Sciences (AREA)
• Life Sciences & Earth Sciences (AREA)
• Hematology (AREA)
• Immunology (AREA)
• Engineering & Computer Science (AREA)
• Urology & Nephrology (AREA)
• Molecular Biology (AREA)
• Chemical & Material Sciences (AREA)
• Biomedical Technology (AREA)
• Physics & Mathematics (AREA)
• Microbiology (AREA)
• Cell Biology (AREA)
• Food Science & Technology (AREA)
• Medicinal Chemistry (AREA)
• Biotechnology (AREA)
• Analytical Chemistry (AREA)
• Biochemistry (AREA)
• General Health & Medical Sciences (AREA)
• General Physics & Mathematics (AREA)
• Pathology (AREA)
• Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
• Investigating Or Analysing Biological Materials (AREA)

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• 2006
  • 2006-08-01 EP EP06789202A patent/EP1920253A2/de not_active Withdrawn
  • 2006-08-01 WO PCT/US2006/030107 patent/WO2007027353A2/en not_active Ceased

Patent Citations (3)

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