EP1922405A4 - Genes issus de d'actinobacillus succinogenes 130z (atcc 55618) pour la production d'agents chimiques issus de la voie c4 d'a. succinogenes - Google Patents

Genes issus de d'actinobacillus succinogenes 130z (atcc 55618) pour la production d'agents chimiques issus de la voie c4 d'a. succinogenes

Info

Publication number
EP1922405A4
EP1922405A4 EP06800746A EP06800746A EP1922405A4 EP 1922405 A4 EP1922405 A4 EP 1922405A4 EP 06800746 A EP06800746 A EP 06800746A EP 06800746 A EP06800746 A EP 06800746A EP 1922405 A4 EP1922405 A4 EP 1922405A4
Authority
EP
European Patent Office
Prior art keywords
succinogenes
atcc
genes
routes
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06800746A
Other languages
German (de)
English (en)
Other versions
EP1922405A2 (fr
Inventor
J Gregory Zeikus
James B Mckinlay
Maris Laivenieks
Claire Vieille
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Michigan State University MSU
Original Assignee
Michigan State University MSU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michigan State University MSU filed Critical Michigan State University MSU
Publication of EP1922405A2 publication Critical patent/EP1922405A2/fr
Publication of EP1922405A4 publication Critical patent/EP1922405A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/50—Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP06800746A 2005-08-05 2006-08-04 Genes issus de d'actinobacillus succinogenes 130z (atcc 55618) pour la production d'agents chimiques issus de la voie c4 d'a. succinogenes Withdrawn EP1922405A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70584105P 2005-08-05 2005-08-05
PCT/US2006/030425 WO2007019301A2 (fr) 2005-08-05 2006-08-04 Genes issus de d'actinobacillus succinogenes 130z (atcc 55618) pour la production d'agents chimiques issus de la voie c4 d'a. succinogenes

Publications (2)

Publication Number Publication Date
EP1922405A2 EP1922405A2 (fr) 2008-05-21
EP1922405A4 true EP1922405A4 (fr) 2009-04-01

Family

ID=37727918

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06800746A Withdrawn EP1922405A4 (fr) 2005-08-05 2006-08-04 Genes issus de d'actinobacillus succinogenes 130z (atcc 55618) pour la production d'agents chimiques issus de la voie c4 d'a. succinogenes

Country Status (7)

Country Link
EP (1) EP1922405A4 (fr)
KR (1) KR20080031504A (fr)
CN (1) CN101278041A (fr)
BR (1) BRPI0614716A2 (fr)
CA (1) CA2618694A1 (fr)
MX (1) MX2008001716A (fr)
WO (1) WO2007019301A2 (fr)

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BRPI0819717B1 (pt) 2007-11-20 2022-05-17 Dsm Ip Assets B.V. Levedura recombinante e processo para a produção de ácido succínico
ATE555203T1 (de) 2007-11-20 2012-05-15 Dsm Ip Assets Bv Dicarbonsäureproduktion in eukaryonten
WO2013163628A2 (fr) 2012-04-27 2013-10-31 Duke University Correction génétique de gènes ayant subi une mutation
BE1021047B1 (fr) * 2013-01-18 2015-02-25 Man To Tree S.A. Actinobacillus succinogenes genetiquement modifiee et son utilisation pour la production d'acide succinique
CN103981203B (zh) * 2013-02-07 2018-01-12 中国科学院天津工业生物技术研究所 5‑氨基乙酰丙酸高产菌株及其制备方法和应用
US9828582B2 (en) 2013-03-19 2017-11-28 Duke University Compositions and methods for the induction and tuning of gene expression
CN105849555B (zh) * 2013-12-18 2019-05-14 加利福尼亚太平洋生物科学股份有限公司 用于错误校正的序列读数迭代聚类
CN103695364B (zh) * 2014-01-14 2018-02-02 中国科学院天津工业生物技术研究所 通过弱化5‑氨基乙酰丙酸脱水酶活性获得5‑氨基乙酰丙酸高产菌株及其应用
CN103710374B (zh) * 2014-01-14 2018-02-06 中国科学院天津工业生物技术研究所 一种5‑氨基乙酰丙酸产生菌株及其制备方法与应用
KR20160117572A (ko) 2014-02-07 2016-10-10 바스프 에스이 수크로스 상의 정밀 화학물질의 개선된 생산을 위한 변형된 미생물
CN104357497B (zh) * 2014-10-22 2018-04-27 江南大学 一种提高产酸丙酸杆菌丙酸产量的方法
WO2016130600A2 (fr) 2015-02-09 2016-08-18 Duke University Compositions et procédés pour l'édition de l'épigénome
EP4089175A1 (fr) 2015-10-13 2022-11-16 Duke University Ingénierie génomique avec systèmes crispr de type i dans des cellules eucaryotes
KR102787119B1 (ko) 2015-11-30 2025-03-27 듀크 유니버시티 유전자 편집에 의한 인간 디스트로핀 유전자의 교정을 위한 치료용 표적 및 사용 방법
US20190127713A1 (en) 2016-04-13 2019-05-02 Duke University Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
JP7490211B2 (ja) 2016-07-19 2024-05-27 デューク ユニバーシティ Ｃｐｆ１に基づくゲノム編集の治療適用
US10428359B2 (en) * 2016-10-03 2019-10-01 Ajinomoto Co, Inc. Method for producing L-amino acid
KR20200009010A (ko) * 2017-05-19 2020-01-29 바스프 에스이 유기 화합물 제조 방법
EP3740580A4 (fr) 2018-01-19 2021-10-20 Duke University Ingénierie génomique avec des systèmes crispr-cas dans des eucaryotes
CN108517327B (zh) * 2018-04-20 2020-10-30 中国科学院天津工业生物技术研究所 5-氨基乙酰丙酸高产菌株及其制备方法和应用
CN110904018B (zh) * 2018-09-14 2022-09-09 中国科学院天津工业生物技术研究所 5-氨基乙酰丙酸生产菌株及其构建方法和应用
US20230383297A1 (en) * 2020-10-09 2023-11-30 Duke University Novel targets for reactivation of prader-willi syndrome-associated genes
WO2023095896A1 (fr) * 2021-11-26 2023-06-01 Dic株式会社 Micro-organisme génétiquement modifié et procédé de production d'asparagine
IL317874A (en) 2022-06-24 2025-02-01 Tune Therapeutics Inc Compounds, systems and methods for reducing low density lipoproteins through targeted gene suppression

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US6696561B1 (en) * 1909-07-09 2004-02-24 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
US20030087381A1 (en) * 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
US6495023B1 (en) * 1998-07-09 2002-12-17 Michigan State University Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration
US6599732B1 (en) * 1999-06-29 2003-07-29 Archer-Daniels-Midland Company Regulation of carbon assimilation
WO2004044210A2 (fr) * 2002-11-06 2004-05-27 University Of Florida Materiaux et procedes permettant une bonne production d'acetate et d'autres produits
AU2004245988A1 (en) * 2003-05-30 2004-12-16 Microbia, Inc. Methods and compositions for amino acid production
US7393669B2 (en) * 2003-07-07 2008-07-01 Fluxome Sciences A/S Metabolically engineered micro-organisms having improved galactose uptake
US7163812B2 (en) * 2003-08-06 2007-01-16 Board Of Trustees Of Michigan State University Actinobacillus succinogenes shuttle vector and methods of use

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHOTANI G ET AL: "The commercial production of chemicals using pathway engineering", BIOCHIMICA ET BIOPHYSICA ACTA - PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGIE, ELSEVIER SCIENCE BV, AMSTERDAM, NL, vol. 1543, no. 2, 29 December 2000 (2000-12-29), pages 434 - 455, XP004279117, ISSN: 0167-4838 *
DATABASE NCBI 3 November 2004 (2004-11-03), LAIVENIEKS ET AL.: "Actinobacillus succinogenes mdh gene cloning and recombinant enzyme", Database accession no. AY773261 *
KIM P ET AL: "Effect of Overexpression of Actinobacillus succinogenes Phosphoenolpyruvate Carboxykinase on Succinate Production in Escherichia coli", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 70, no. 2, 1 February 2004 (2004-02-01), pages 1238 - 1241, XP002999937, ISSN: 0099-2240 *
KIM PIL ET AL: "Construction of a shuttle vector for the overexpression of recombinant proteins in Actinobacillus succinogenes", PLASMID, NEW YORK,NY, US, vol. 51, no. 2, 1 March 2004 (2004-03-01), pages 108 - 115, XP009109260, ISSN: 0147-619X *
ZEIKUS J G ET AL: "Biotechnology of succinic acid production and markets for derived industrial products", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER VERLAG, BERLIN, DE, vol. 51, no. 5, 1 May 1999 (1999-05-01), pages 545 - 552, XP002175988, ISSN: 0175-7598 *

Also Published As

Publication number Publication date
BRPI0614716A2 (pt) 2011-04-12
WO2007019301A2 (fr) 2007-02-15
CN101278041A (zh) 2008-10-01
WO2007019301A3 (fr) 2007-07-12
KR20080031504A (ko) 2008-04-08
CA2618694A1 (fr) 2007-02-15
MX2008001716A (es) 2008-04-07
EP1922405A2 (fr) 2008-05-21

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

RIN1 Information on inventor provided before grant (corrected)

Inventor name: VIEILLE, CLAIRE

Inventor name: ZEIKUS, J., GREGORY

Inventor name: MCKINLAY, JAMES, B.

Inventor name: LAIVENIEKS, MARIS

A4 Supplementary search report drawn up and despatched

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