EP2007875A4 - Cellules dérivées du derme pour des applications de génie histologique - Google Patents

Cellules dérivées du derme pour des applications de génie histologique

Info

Publication number
EP2007875A4
EP2007875A4 EP07760205A EP07760205A EP2007875A4 EP 2007875 A4 EP2007875 A4 EP 2007875A4 EP 07760205 A EP07760205 A EP 07760205A EP 07760205 A EP07760205 A EP 07760205A EP 2007875 A4 EP2007875 A4 EP 2007875A4
Authority
EP
European Patent Office
Prior art keywords
cells
leather skin
tissue breeding
breeding
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07760205A
Other languages
German (de)
English (en)
Other versions
EP2007875A2 (fr
Inventor
Kyriacos A Athanasiou
Ying Deng
Jerry Hu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
William Marsh Rice University
Original Assignee
William Marsh Rice University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by William Marsh Rice University filed Critical William Marsh Rice University
Publication of EP2007875A2 publication Critical patent/EP2007875A2/fr
Publication of EP2007875A4 publication Critical patent/EP2007875A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/76—Agarose, agar-agar

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Vascular Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
EP07760205A 2006-04-05 2007-04-05 Cellules dérivées du derme pour des applications de génie histologique Withdrawn EP2007875A4 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78985506P 2006-04-05 2006-04-05
US78985306P 2006-04-05 2006-04-05
US78985106P 2006-04-05 2006-04-05
PCT/US2007/066085 WO2007136936A2 (fr) 2006-04-05 2007-04-05 Cellules dérivées du derme pour des applications de génie histologique

Publications (2)

Publication Number Publication Date
EP2007875A2 EP2007875A2 (fr) 2008-12-31
EP2007875A4 true EP2007875A4 (fr) 2009-12-16

Family

ID=38564326

Family Applications (3)

Application Number Title Priority Date Filing Date
EP20070760209 Withdrawn EP2007312A4 (fr) 2006-04-05 2007-04-05 Approche basée sur la forme pour ingéniérie tissulaire sans échafaudage
EP07760205A Withdrawn EP2007875A4 (fr) 2006-04-05 2007-04-05 Cellules dérivées du derme pour des applications de génie histologique
EP07760211A Withdrawn EP2007881A4 (fr) 2006-04-05 2007-04-05 Ingéniérie tissulaire utilisant des cellules souches embryonnaires humaines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP20070760209 Withdrawn EP2007312A4 (fr) 2006-04-05 2007-04-05 Approche basée sur la forme pour ingéniérie tissulaire sans échafaudage

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP07760211A Withdrawn EP2007881A4 (fr) 2006-04-05 2007-04-05 Ingéniérie tissulaire utilisant des cellules souches embryonnaires humaines

Country Status (4)

Country Link
EP (3) EP2007312A4 (fr)
AU (3) AU2007234365A1 (fr)
CA (3) CA2648327A1 (fr)
WO (3) WO2007136936A2 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2396689T3 (es) 2003-12-11 2013-02-25 Isto Technologies Inc. Sistema de cartílago particulado
US8241905B2 (en) 2004-02-24 2012-08-14 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
WO2010022074A1 (fr) * 2008-08-18 2010-02-25 William Marsh Rice University Procédé de décellularisation pour cartilage articulaire modifié de tissu sans échafaudage ou pour tissu de cartilage natif
US20110212894A1 (en) * 2004-07-09 2011-09-01 Athanasiou Kyriacos A Decellularization method for scaffoldless tissue engineered articular cartilage or native cartilage tissue
EP1916964A4 (fr) 2005-08-26 2015-11-04 Zimmer Inc Implants et procedes pour la reparation, le remplacement et le traitement de maladies articulaires
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
AU2008240191B2 (en) 2007-04-12 2013-09-19 Zimmer, Inc. Compositions and methods for tissue repair
CA2718174A1 (fr) * 2008-03-03 2009-09-11 William Marsh Rice University Procedes de fabrication d'un cartilage ameliore d'ingenierie tissulaire
EP2310491B1 (fr) * 2008-06-20 2018-03-07 Universiteit Maastricht Modules de tissus auto-assemblés
JP5624981B2 (ja) 2008-06-24 2014-11-12 ザ・キュレーターズ・オブ・ザ・ユニバーシティ・オブ・ミズーリＴｈｅ Ｃｕｒａｔｏｒｓ Ｏｆｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍｉｓｓｏｕｒｉ 自己集合性多細胞体、および前記多細胞体を用いて３次元の生物構造体を作製する方法
CN105796601A (zh) * 2009-07-16 2016-07-27 生物时代股份有限公司 用于体外和体内软骨发生的方法和组合物
AU2011318437B2 (en) 2010-10-21 2015-02-26 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
US10865383B2 (en) 2011-07-12 2020-12-15 Lineage Cell Therapeutics, Inc. Methods and formulations for orthopedic cell therapy
HK1200483A1 (en) 2011-09-12 2015-08-07 奥加诺沃公司 Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same
US9499779B2 (en) 2012-04-20 2016-11-22 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
US9442105B2 (en) 2013-03-15 2016-09-13 Organovo, Inc. Engineered liver tissues, arrays thereof, and methods of making the same
SG11201600770RA (en) 2013-07-31 2016-02-26 Organovo Inc Automated devices, systems, and methods for the fabrication of tissue
EP3808838B1 (fr) 2014-04-04 2024-04-10 Organovo, Inc. Tissu mammaire tridimensionnel artificiel, tissu adipeux, et modèle de maladies tumorales
US9670443B2 (en) * 2014-06-25 2017-06-06 University Of Leeds Tissue engineered constructs
KR20170064547A (ko) 2014-10-06 2017-06-09 오가노보, 인크. 조작된 신장 조직, 이의 어레이, 및 이를 제조하는 방법
US11529436B2 (en) 2014-11-05 2022-12-20 Organovo, Inc. Engineered three-dimensional skin tissues, arrays thereof, and methods of making the same
WO2017083402A1 (fr) 2015-11-09 2017-05-18 Organovo, Inc. Procédés améliorés de fabrication de tissus

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084385A2 (fr) * 2002-04-02 2003-10-16 William Marsh Rice University Cellules redifferenciees utilisees pour reparer les defauts du cartilage

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WO1997017038A1 (fr) * 1995-11-09 1997-05-15 University Of Massachusetts Regeneration de surfaces tissulaires a l'aide de compositions hydrogel-cellules
BR0008714A (pt) * 1999-03-02 2002-01-02 Univ Massachusetts Public Inst Linhagens celulares embriÈnicas ou tipo tronco produzidas por transplante nuclear de espécies cruzadas
JP2004504834A (ja) * 2000-08-01 2004-02-19 イスム　リサーチ　ディベロップメント　カンパニー 胚性細胞の定方向分化
WO2002072762A2 (fr) * 2001-03-08 2002-09-19 Advanced Cell Technology, Inc. Utilisation d'interference de l'arn pour produire des cellules souches de lignee specifique et d'autres cellules non differenciees, et production de cellules differenciees in vitro par coculture
CN1599793A (zh) * 2001-12-07 2005-03-23 杰龙公司 人胚胎干细胞衍生的软骨细胞前体
US20020106625A1 (en) * 2002-02-07 2002-08-08 Hung Clark T. Bioreactor for generating functional cartilaginous tissue
US20040082063A1 (en) * 2002-10-18 2004-04-29 Reliance Life Sciences Pvt. Ltd. Tissue-like organization of cells and macroscopic tissue-like constructs, generated by macromass culture of cells, and the method of macromass culture
ES2420304T3 (es) * 2004-07-09 2013-08-23 William Marsh Rice University Constructos sin soporte para ingeniería de tejido de cartílago articular

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084385A2 (fr) * 2002-04-02 2003-10-16 William Marsh Rice University Cellules redifferenciees utilisees pour reparer les defauts du cartilage

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DENG YING ET AL: "Isolation and chondroinduction of a dermis-isolated, aggrecan-sensitive subpopulation with high chondrogenic potential", ARTHRITIS & RHEUMATISM, vol. 56, no. 1, January 2007 (2007-01-01), pages 168 - 176, XP002553188, ISSN: 0004-3591 *
See also references of WO2007136936A2 *

Also Published As

Publication number Publication date
WO2007136936A2 (fr) 2007-11-29
AU2007234366A1 (en) 2007-10-11
WO2007115337A2 (fr) 2007-10-11
EP2007312A4 (fr) 2012-08-22
CA2648327A1 (fr) 2007-10-11
AU2007234365A1 (en) 2007-10-11
WO2007115336A2 (fr) 2007-10-11
EP2007312A2 (fr) 2008-12-31
CA2648648A1 (fr) 2007-11-29
WO2007136936A3 (fr) 2008-10-23
WO2007115337A8 (fr) 2007-12-13
EP2007881A4 (fr) 2009-07-08
WO2007115337A3 (fr) 2008-07-03
AU2007254048A1 (en) 2007-11-29
EP2007875A2 (fr) 2008-12-31
EP2007881A2 (fr) 2008-12-31
WO2007115336A3 (fr) 2008-05-22
CA2648332A1 (fr) 2007-10-11

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: HU, JERRY

Inventor name: DENG, YING

Inventor name: ATHANASIOU, KYRIACOS, A.

A4 Supplementary search report drawn up and despatched

Effective date: 20091113

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