EP2021499A4 - FUNCTIONAL NETWORKS FOR THE HIGH-FREQUENCY CHARACTERIZATION OF ELEMENTS REGULATING GENE EXPRESSION - Google Patents

FUNCTIONAL NETWORKS FOR THE HIGH-FREQUENCY CHARACTERIZATION OF ELEMENTS REGULATING GENE EXPRESSION

Info

Publication number
EP2021499A4
EP2021499A4 EP06849046A EP06849046A EP2021499A4 EP 2021499 A4 EP2021499 A4 EP 2021499A4 EP 06849046 A EP06849046 A EP 06849046A EP 06849046 A EP06849046 A EP 06849046A EP 2021499 A4 EP2021499 A4 EP 2021499A4
Authority
EP
European Patent Office
Prior art keywords
gene expression
regulating gene
functional networks
elements regulating
frequency characterization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP06849046A
Other languages
German (de)
French (fr)
Other versions
EP2021499A2 (en
Inventor
Nathan D Trinklein
Shelley F Aldred
Sara J Cooper
Richard M Myers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/636,385 external-priority patent/US20070161031A1/en
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of EP2021499A2 publication Critical patent/EP2021499A2/en
Publication of EP2021499A4 publication Critical patent/EP2021499A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP06849046A 2005-12-16 2006-12-08 FUNCTIONAL NETWORKS FOR THE HIGH-FREQUENCY CHARACTERIZATION OF ELEMENTS REGULATING GENE EXPRESSION Ceased EP2021499A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75092905P 2005-12-16 2005-12-16
US76205606P 2006-01-24 2006-01-24
US11/636,385 US20070161031A1 (en) 2005-12-16 2006-12-07 Functional arrays for high throughput characterization of gene expression regulatory elements
PCT/US2006/046920 WO2007078599A2 (en) 2005-12-16 2006-12-08 Functional arrays for high throughput characterization of gene expression regulatory elements

Publications (2)

Publication Number Publication Date
EP2021499A2 EP2021499A2 (en) 2009-02-11
EP2021499A4 true EP2021499A4 (en) 2010-02-17

Family

ID=38228711

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06849046A Ceased EP2021499A4 (en) 2005-12-16 2006-12-08 FUNCTIONAL NETWORKS FOR THE HIGH-FREQUENCY CHARACTERIZATION OF ELEMENTS REGULATING GENE EXPRESSION

Country Status (3)

Country Link
EP (1) EP2021499A4 (en)
JP (1) JP2009519710A (en)
WO (1) WO2007078599A2 (en)

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WO2011146411A1 (en) * 2010-05-17 2011-11-24 University Of Southern California Grp78 gene polymorphism rs391957 is associated with tumor recurrence and survival in gastrointestinal cancer patients
CN103608455B (en) * 2011-01-07 2019-01-15 应用遗传科技公司 Promoters, expression cassettes, vectors, kits and methods for the treatment of color blindness and other diseases
WO2013151058A1 (en) * 2012-04-03 2013-10-10 独立行政法人国立成育医療研究センター DNA CONTROLLING miR-140 EXPRESSION, AND SCREENING METHOD OF DRUGS USING SAID DNA
US9163259B2 (en) 2012-05-04 2015-10-20 Novartis Ag Viral vectors for the treatment of retinal dystrophy
WO2014031079A1 (en) * 2012-08-21 2014-02-27 Singapore Health Services Pte Ltd Method and/or probe for determining glaucoma susceptibility
KR102495527B1 (en) * 2013-03-14 2023-02-06 몬산토 테크놀로지 엘엘씨 Plant regulatory elements and uses thereof
WO2014197586A1 (en) 2013-06-04 2014-12-11 Virginia Commonwealth University Mda-9/syntenin promoter to image and treat metastatic cancer cells
PL3097197T3 (en) * 2014-01-21 2021-06-28 Vrije Universiteit Brussel Muscle-specific regulatory elements of nucleic acids and methods and their application
US20150276767A1 (en) * 2014-03-12 2015-10-01 The University Of Sydney Systems and methods for identifying cancers having activated progesterone receptors
ES2719122T3 (en) * 2014-03-21 2019-07-08 Life Technologies Corp Multi-copy reference test
CN103981185B (en) * 2014-04-14 2016-04-27 浙江理工大学 Liver cancer-specific GP73 core promoter and screening construction process thereof
KR101791296B1 (en) * 2014-04-17 2017-10-27 제주대학교 산학협력단 Expression cassette and vector with genes related Alzheimer's disease and transgenic cell line made from it
RU2017112748A (en) 2014-11-17 2018-12-19 Арно Терапьютикс, Инк. ONAPRISTON COMPOSITIONS OF LONG-TERM ACTIONS AND METHODS
CN104673797B (en) * 2015-02-09 2018-02-02 苏州大学 Participate in long-chain non-coding RNA and its application of human body cell ionising radiation stress reaction
WO2016149455A2 (en) * 2015-03-17 2016-09-22 The General Hospital Corporation The rna interactome of polycomb repressive complex 1 (prc1)
EP3307888A1 (en) * 2015-06-12 2018-04-18 Erasmus University Medical Center Rotterdam New crispr assays
CA2998924A1 (en) 2015-09-25 2017-03-30 Context Biopharma Inc. Methods of making onapristone intermediates
CA3008422A1 (en) 2015-12-15 2017-06-22 Context Biopharma Inc. Amorphous onapristone compositions and methods of making the same
MX2018009542A (en) 2016-02-04 2018-11-09 Zhu Zhenglun Treatment and diagnosis of inflammatory disorders.
WO2023150553A1 (en) * 2022-02-01 2023-08-10 University Of Rochester Gpr17 promoter-based targeting and transduction of glial progenitor cells
MX2018012537A (en) 2016-04-15 2019-02-25 Univ Pennsylvania Gene therapy for treating hemophilia a.
US20180148471A1 (en) 2016-11-30 2018-05-31 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection
WO2018111104A1 (en) * 2016-12-14 2018-06-21 Erasmus University Medical Center Rotterdam Use of human crispr sequences in diagnostics
WO2018178067A1 (en) * 2017-03-27 2018-10-04 Vrije Universiteit Brussel Diaphragm-specific nucleic acid regulatory elements and methods and use thereof
MX2019011772A (en) * 2017-04-03 2020-01-09 Encoded Therapeutics Inc SELECTIVE TRANSGENIC EXPRESSION OF TISSUES.
JP7119009B2 (en) 2017-05-31 2022-08-16 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル Optimized human coagulation factor IX gene expression cassettes and their uses
RU2671156C1 (en) * 2017-08-21 2018-10-29 Общество с ограниченной ответственностью "Центр Генетики и Репродуктивной Медицины "ГЕНЕТИКО" Method of preimplantation genetic diagnostics of type 1 spinal muscular atrophy
WO2019097122A1 (en) * 2017-11-20 2019-05-23 Turun Yliopisto A novel cip2a variant and uses thereof
EP3717505A4 (en) 2017-12-01 2021-12-01 Encoded Therapeutics, Inc. MODIFIED DNA BINDING PROTEINS
AU2019227910B2 (en) 2018-02-28 2025-07-17 The Regents Of The University Of California A modular system for gene and protein delivery based on AAV
US12274733B2 (en) 2018-09-28 2025-04-15 President And Fellows Of Harvard College Cellular reprogramming to reverse aging and promote organ and tissue regeneration
IL281470B2 (en) 2018-09-28 2025-08-01 Harvard College Cell reprogramming to reverse aging and promote organ and tissue regeneration
KR20210086644A (en) * 2018-10-31 2021-07-08 럿거스, 더 스테이트 유니버시티 오브 뉴 저지 GRAMC: Genome Scale Reporter Analysis Method for CIS Regulatory Module
FR3088194B1 (en) * 2018-11-09 2021-02-19 Univ Paris Sud USING THE MICRORNA MIR-27A-5P TO TREAT CLOSTRIDIUM DIFFICILE INTESTINAL INFLAMMATION
US20220073905A1 (en) * 2018-12-28 2022-03-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods and materials for single cell transcriptome-based development of aav vectors and promoters
EP3947700A4 (en) 2019-04-01 2023-01-04 Tenaya Therapeutics, Inc. ADENO-ASSOCIATED VIRUS INCLUDING A MODIFIED CAPSID
KR102192455B1 (en) * 2019-04-05 2020-12-17 한국과학기술원 A cancer diagnosis marker based on ATAC-Seq and Method using the same
WO2020204297A1 (en) * 2019-04-05 2020-10-08 한국과학기술원 Cancer diagnostic marker using transposase-accessible chromatin sequencing information about individual, and use thereof
PL3976798T3 (en) 2019-05-29 2026-04-07 Encoded Therapeutics, Inc. COMPOSITIONS AND METHODS OF SELECTIVE GENE REGULATION
CN110117659B (en) * 2019-06-18 2022-10-11 上海奕谱生物科技有限公司 Novel tumor marker STAMP-EP10 and application thereof
JP2023525969A (en) * 2020-05-19 2023-06-20 イグザカ フランス Promoter sequences for expression of gene therapy products in CD3+ cells in vitro and in vivo
CN115243705A (en) 2020-05-27 2022-10-25 苏黎世大学 Novel transduction enhancers and uses thereof
CA3190092A1 (en) * 2020-08-21 2022-02-24 Felix MUERDTER Methods and systems for sequence generation and prediction
JP2023540553A (en) * 2020-09-07 2023-09-25 サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、（セーエヌエルエス） Eukaryotic DNA replication origins and vectors containing the same
US11781156B2 (en) 2020-10-09 2023-10-10 Tenaya Therapeutics, Inc. Plakophillin-2 gene therapy methods and compositions
BR112023006305A2 (en) 2020-10-09 2023-05-09 Tenaya Therapeutics Inc METHODS AND COMPOSITIONS OF GENE THERAPY WITH PLACOFILLIN-2
US11464872B2 (en) * 2020-12-07 2022-10-11 Noga Therapeutics Ltd. Lentiviral vectors for therapeutic expression of BTK in haematopoietic cells
WO2022212766A2 (en) * 2021-03-31 2022-10-06 Hunterian Medicine Llc Compact promoters for gene expression
CN113265428B (en) * 2021-06-11 2023-03-14 东北林业大学 Detection system for constructing copper change in living cells by utilizing metallothionein and application
CN119654412A (en) * 2022-06-27 2025-03-18 中美瑞康核酸技术(南通)研究院有限公司 Oligonucleotide modulators that activate complement factor H expression
WO2024110770A1 (en) * 2022-11-22 2024-05-30 INSERM (Institut National de la Santé et de la Recherche Médicale) A new promoter for retinal pigment epithelium (rpe) targeted gene therapy
US12252518B2 (en) 2023-01-06 2025-03-18 Life Biosciences, Inc. Methods of treating non-arteritic anterior ischemic optic neuropathy
WO2025171086A1 (en) * 2024-02-07 2025-08-14 Asimov Inc. Promoters and uses thereof
WO2026030244A1 (en) * 2024-07-30 2026-02-05 Kate Therapeutics, Inc. Adeno-associated virus compositions for the treatment of limb girdle muscular dystrophy 2a

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Also Published As

Publication number Publication date
WO2007078599A9 (en) 2007-10-04
JP2009519710A (en) 2009-05-21
WO2007078599A2 (en) 2007-07-12
EP2021499A2 (en) 2009-02-11
WO2007078599A3 (en) 2008-08-28
WO2007078599A8 (en) 2008-10-30

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