EP2021499A4 - Funktionelle arrays zur kennzeichnung von elementen zur genexpressionsregulierung mit hohem durchsatz - Google Patents

Funktionelle arrays zur kennzeichnung von elementen zur genexpressionsregulierung mit hohem durchsatz

Info

Publication number
EP2021499A4
EP2021499A4 EP06849046A EP06849046A EP2021499A4 EP 2021499 A4 EP2021499 A4 EP 2021499A4 EP 06849046 A EP06849046 A EP 06849046A EP 06849046 A EP06849046 A EP 06849046A EP 2021499 A4 EP2021499 A4 EP 2021499A4
Authority
EP
European Patent Office
Prior art keywords
gene expression
regulating gene
functional networks
elements regulating
frequency characterization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP06849046A
Other languages
English (en)
French (fr)
Other versions
EP2021499A2 (de
Inventor
Nathan D Trinklein
Shelley F Aldred
Sara J Cooper
Richard M Myers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/636,385 external-priority patent/US20070161031A1/en
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of EP2021499A2 publication Critical patent/EP2021499A2/de
Publication of EP2021499A4 publication Critical patent/EP2021499A4/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP06849046A 2005-12-16 2006-12-08 Funktionelle arrays zur kennzeichnung von elementen zur genexpressionsregulierung mit hohem durchsatz Ceased EP2021499A4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75092905P 2005-12-16 2005-12-16
US76205606P 2006-01-24 2006-01-24
US11/636,385 US20070161031A1 (en) 2005-12-16 2006-12-07 Functional arrays for high throughput characterization of gene expression regulatory elements
PCT/US2006/046920 WO2007078599A2 (en) 2005-12-16 2006-12-08 Functional arrays for high throughput characterization of gene expression regulatory elements

Publications (2)

Publication Number Publication Date
EP2021499A2 EP2021499A2 (de) 2009-02-11
EP2021499A4 true EP2021499A4 (de) 2010-02-17

Family

ID=38228711

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06849046A Ceased EP2021499A4 (de) 2005-12-16 2006-12-08 Funktionelle arrays zur kennzeichnung von elementen zur genexpressionsregulierung mit hohem durchsatz

Country Status (3)

Country Link
EP (1) EP2021499A4 (de)
JP (1) JP2009519710A (de)
WO (1) WO2007078599A2 (de)

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WO2014031079A1 (en) * 2012-08-21 2014-02-27 Singapore Health Services Pte Ltd Method and/or probe for determining glaucoma susceptibility
JP6580027B2 (ja) 2013-03-14 2019-09-25 モンサント テクノロジー エルエルシー 植物調節エレメントおよびその使用
EP3004872B1 (de) * 2013-06-04 2017-10-18 Virginia Commonwealth University Mda-9/syntenin-promotor zur abbildung und behandlung metastatischer krebszellen
SG11201605906UA (en) 2014-01-21 2016-08-30 Univ Bruxelles Muscle-specific nucleic acid regulatory elements and methods and use thereof
US20150276767A1 (en) * 2014-03-12 2015-10-01 The University Of Sydney Systems and methods for identifying cancers having activated progesterone receptors
EP3546594B1 (de) 2014-03-21 2020-12-23 Life Technologies Corporation Mehrfachkopie-referenzassay
CN103981185B (zh) * 2014-04-14 2016-04-27 浙江理工大学 肝癌特异性gp73核心启动子及其筛选构建方法
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HK1246653A1 (zh) 2014-11-17 2018-09-14 Context Biopharma Inc. 奥那司酮延长释放组合物和方法
CN104673797B (zh) * 2015-02-09 2018-02-02 苏州大学 参与人体细胞电离辐射应激反应的长链非编码rna及其应用
WO2016149455A2 (en) * 2015-03-17 2016-09-22 The General Hospital Corporation The rna interactome of polycomb repressive complex 1 (prc1)
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US10308676B2 (en) 2015-09-25 2019-06-04 Context Biopharma Inc. Methods of making onapristone intermediates
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EP3452102B9 (de) 2016-04-15 2024-09-04 The Trustees of The University of Pennsylvania Gentherapie zur behandlung von hämophilie a
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WO2018111104A1 (en) * 2016-12-14 2018-06-21 Erasmus University Medical Center Rotterdam Use of human crispr sequences in diagnostics
EP3600445A1 (de) * 2017-03-27 2020-02-05 Vrije Universiteit Brussel Membranspezifische regulatorische nukleinsäureelemente und verfahren und verwendung davon
EA201992358A1 (ru) * 2017-04-03 2020-03-24 Инкоудид Терапьютикс, Инк. Тканеселективная экспрессия трансгена
WO2018222792A1 (en) 2017-05-31 2018-12-06 The University Of North Carolina At Chapel Hill Optimized human clotting factor ix gene expression cassettes and their use
RU2671156C1 (ru) * 2017-08-21 2018-10-29 Общество с ограниченной ответственностью "Центр Генетики и Репродуктивной Медицины "ГЕНЕТИКО" Способ преимплантационной генетической диагностики спинальной мышечной атрофии типа 1
WO2019097122A1 (en) * 2017-11-20 2019-05-23 Turun Yliopisto A novel cip2a variant and uses thereof
JP7401432B2 (ja) 2017-12-01 2023-12-19 エンコーデッド セラピューティクス， インコーポレイテッド 操作されたｄｎａ結合タンパク質
AU2019227910B2 (en) 2018-02-28 2025-07-17 The Regents Of The University Of California A modular system for gene and protein delivery based on AAV
US12274733B2 (en) 2018-09-28 2025-04-15 President And Fellows Of Harvard College Cellular reprogramming to reverse aging and promote organ and tissue regeneration
EP3856226B1 (de) 2018-09-28 2026-02-18 President and Fellows of Harvard College Zelluläre umprogrammierung zur umkehrung der alterung und zur förderung der organ- und geweberegeneration
EP3856260A1 (de) 2018-09-28 2021-08-04 President and Fellows of Harvard College Mutante reverse tetracyclin-transaktivatoren zur expression von genen
CA3116174A1 (en) * 2018-10-31 2020-05-07 Rutgers, The State University Of New Jersey Gramc: genome-scale reporter assay method for cis-regulatory modules
FR3088194B1 (fr) 2018-11-09 2021-02-19 Univ Paris Sud Utilisation du microrna mir-27a-5p pour traiter l'inflammation intestinale induite par clostridium difficile
US20220073905A1 (en) * 2018-12-28 2022-03-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods and materials for single cell transcriptome-based development of aav vectors and promoters
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KR102192455B1 (ko) * 2019-04-05 2020-12-17 한국과학기술원 개인의 전이효소-접근가능한 염색질 시퀀싱 정보를 이용한 암 진단 마커 및 이의 용도
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CN110117659B (zh) * 2019-06-18 2022-10-11 上海奕谱生物科技有限公司 一种新型的肿瘤标记物stamp-ep10及其应用
WO2021234455A2 (en) * 2020-05-19 2021-11-25 Ixaka France Promoter sequences for in vitro and in vivo expression of gene therapy products in cd3+ cells
CA3163572A1 (en) 2020-05-27 2021-12-02 Oleksandr PASTUKHOV Novel transduction enhancers and uses thereof
CN116391230A (zh) * 2020-08-21 2023-07-04 瑞泽恩制药公司 用于序列生成和预测的方法和系统
WO2022049295A1 (en) * 2020-09-07 2022-03-10 Centre National De La Recherche Scientifique Eukaryotic dna replication origins, and vector containing the same
JP7415042B2 (ja) * 2020-10-09 2024-01-16 テナヤ セラピューティクス， インコーポレイテッド プラコフィリン２遺伝子治療の方法および組成物
US11781156B2 (en) 2020-10-09 2023-10-10 Tenaya Therapeutics, Inc. Plakophillin-2 gene therapy methods and compositions
US11464872B2 (en) * 2020-12-07 2022-10-11 Noga Therapeutics Ltd. Lentiviral vectors for therapeutic expression of BTK in haematopoietic cells
US20240173436A1 (en) * 2021-03-31 2024-05-30 Hunterian Medicine Llc Compact promoters for gene expression
CN113265428B (zh) * 2021-06-11 2023-03-14 东北林业大学 一种利用金属硫蛋白构建活细胞内铜变化的检测系统及应用
CN119654412A (zh) * 2022-06-27 2025-03-18 中美瑞康核酸技术(南通)研究院有限公司 激活补体因子h表达的寡核苷酸调节剂
WO2024110770A1 (en) * 2022-11-22 2024-05-30 INSERM (Institut National de la Santé et de la Recherche Médicale) A new promoter for retinal pigment epithelium (rpe) targeted gene therapy
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Also Published As

Publication number Publication date
WO2007078599A8 (en) 2008-10-30
WO2007078599A2 (en) 2007-07-12
WO2007078599A9 (en) 2007-10-04
EP2021499A2 (de) 2009-02-11
WO2007078599A3 (en) 2008-08-28
JP2009519710A (ja) 2009-05-21

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