EP2155181A4 - 5-htp-kombinationstherapie - Google Patents

5-htp-kombinationstherapie

Info

Publication number: EP2155181A4
Authority: EP; European Patent Office
Prior art keywords: polytherapy; htp; htp polytherapy
Prior art date: 2007-05-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP07776982A

Other languages

English (en)

French (fr)

Other versions

EP2155181A1 (de

Inventor

Connie Sanchez Morillo

Toni D Wolinsky

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

H Lundbeck AS

Original Assignee

H Lundbeck AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-11

Filing date

2007-05-11

Publication date

2012-02-29

2007-05-11 Application filed by H Lundbeck AS filed Critical H Lundbeck AS

2010-02-24 Publication of EP2155181A1 publication Critical patent/EP2155181A1/de

2012-02-29 Publication of EP2155181A4 publication Critical patent/EP2155181A4/de

Status Withdrawn legal-status Critical Current

Links

LDCYZAJDBXYCGN-VIFPVBQESA-N 5-hydroxy-L-tryptophan Chemical compound C1=C(O)C=C2C(C[C@H](N)C(O)=O)=CNC2=C1 LDCYZAJDBXYCGN-VIFPVBQESA-N 0.000 title 1
238000002648 combination therapy Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP07776982A 2007-05-11 2007-05-11 5-htp-kombinationstherapie Withdrawn EP2155181A4 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US2007/011362 WO2008140448A1 (en)	2007-05-11	2007-05-11	5-htp combination therapy

Publications (2)

Publication Number	Publication Date
EP2155181A1 EP2155181A1 (de)	2010-02-24
EP2155181A4 true EP2155181A4 (de)	2012-02-29

Family

ID=40002488

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP07776982A Withdrawn EP2155181A4 (de)	2007-05-11	2007-05-11	5-htp-kombinationstherapie

Country Status (11)

Country	Link
EP (1)	EP2155181A4 (de)
JP (1)	JP2010526804A (de)
KR (1)	KR20100014081A (de)
CN (1)	CN101472575A (de)
AU (1)	AU2007353453A1 (de)
BR (1)	BRPI0712195A2 (de)
CA (1)	CA2655846A1 (de)
EA (1)	EA200870554A1 (de)
IL (1)	IL196041A0 (de)
NO (1)	NO20085278L (de)
WO (1)	WO2008140448A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US11464756B1 (en)	2017-05-19	2022-10-11	Jerry Darm	Mecuna pruriens, L-DOPA and 5-HTP based dietary supplements, pharmaceutical formulations and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6579899B1 (en) *	1998-07-16	2003-06-17	Massachusetts Institute Of Technology	Composition for treatment of stress

2007
- 2007-05-11 CN CNA2007800229678A patent/CN101472575A/zh active Pending
- 2007-05-11 BR BRPI0712195-4A patent/BRPI0712195A2/pt not_active IP Right Cessation
- 2007-05-11 EP EP07776982A patent/EP2155181A4/de not_active Withdrawn
- 2007-05-11 EA EA200870554A patent/EA200870554A1/ru unknown
- 2007-05-11 WO PCT/US2007/011362 patent/WO2008140448A1/en not_active Ceased
- 2007-05-11 AU AU2007353453A patent/AU2007353453A1/en not_active Abandoned
- 2007-05-11 KR KR1020087030898A patent/KR20100014081A/ko not_active Withdrawn
- 2007-05-11 CA CA002655846A patent/CA2655846A1/en not_active Abandoned
- 2007-05-11 JP JP2010507368A patent/JP2010526804A/ja active Pending
2008
- 2008-12-18 IL IL196041A patent/IL196041A0/en unknown
- 2008-12-18 NO NO20085278A patent/NO20085278L/no not_active Application Discontinuation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6579899B1 (en) *	1998-07-16	2003-06-17	Massachusetts Institute Of Technology	Composition for treatment of stress

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
MAGNUSSEN I ET AL: "Treatment of myoclonic syndromes with paroxetine alone or combined with 5-HTP.", ACTA NEUROLOGICA SCANDINAVICA AUG 1982 LNKD- PUBMED:6215817, vol. 66, no. 2, August 1982 (1982-08-01), pages 276 - 282, XP002666757, ISSN: 0001-6314 *
SANCHEZ C ET AL: "Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities", PSYCHOPHARMACOLOGY 200306 DE, vol. 167, no. 4, June 2003 (2003-06-01), pages 353 - 362, XP002666758, ISSN: 0033-3158 *
SANCHEZ C ET AL: "Isolation-induced aggression in mice: effects of 5-hydroxytryptamine uptake inhibitors and involvement of postsynaptic 5-HT1A receptors", EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE, NL, vol. 264, no. 3, 3 November 1994 (1994-11-03), pages 241 - 247, XP023780879, ISSN: 0014-2999, [retrieved on 19941103], DOI: 10.1016/0014-2999(94)00470-6 *
SANCHEZ C ET AL: "R-citalopram inhibits functional and 5-HTP-evoked behavioural responses to the SSRI, escitalopram", PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 200402 US LNKD- DOI:10.1016/J.PBB.2003.12.001, vol. 77, no. 2, February 2004 (2004-02-01), pages 391 - 398, XP002666759, ISSN: 0091-3057 *
See also references of WO2008140448A1 *
TURNER E H ET AL: "Serotonin a la carte: Supplementation with the serotonin precursor 5-hydroxytryptophan", PHARMACOLOGY AND THERAPEUTICS, ELSEVIER, GB, vol. 109, no. 3, 1 March 2006 (2006-03-01), pages 325 - 338, XP025038514, ISSN: 0163-7258, [retrieved on 20060301], DOI: 10.1016/J.PHARMTHERA.2005.06.004 *

Also Published As

Publication number	Publication date
JP2010526804A (ja)	2010-08-05
AU2007353453A1 (en)	2008-11-20
CA2655846A1 (en)	2008-11-20
EP2155181A1 (de)	2010-02-24
KR20100014081A (ko)	2010-02-10
EA200870554A1 (ru)	2009-04-28
BRPI0712195A2 (pt)	2012-01-10
NO20085278L (no)	2009-02-12
WO2008140448A1 (en)	2008-11-20
CN101472575A (zh)	2009-07-01
IL196041A0 (en)	2009-09-01

Legal Events

Date	Code	Title	Description
2010-01-22	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2010-02-24	17P	Request for examination filed	Effective date: 20091211
2010-02-24	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
2010-02-24	AX	Request for extension of the european patent	Extension state: AL BA HR MK RS
2012-02-22	RIC1	Information provided on ipc code assigned before grant	Ipc: A61P 25/22 20060101ALI20120118BHEP Ipc: A61P 25/24 20060101ALI20120118BHEP Ipc: A61K 31/445 20060101ALI20120118BHEP Ipc: A61K 31/405 20060101ALI20120118BHEP Ipc: A61K 31/403 20060101ALI20120118BHEP Ipc: A61K 31/381 20060101ALI20120118BHEP Ipc: A61K 31/343 20060101ALI20120118BHEP Ipc: A61K 31/137 20060101AFI20120118BHEP
2012-02-29	A4	Supplementary search report drawn up and despatched	Effective date: 20120130
2013-01-18	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2013-02-20	18D	Application deemed to be withdrawn	Effective date: 20120828

Publication	Publication Date	Title
NO2022040I1 (no)	2022-09-29	pembrolizumab - forlenget SPC
NO2021031I1 (no)	2021-07-26	Sofosbuvir - forlenget SPC
PT3320912T (pt)	2021-05-24	Imunoterapia à base de indoleamina 2,3-dioxigenase
EP2148908A4 (de)	2012-04-25	Auf polysaccarid basierender kesselsteinhemmer
EP2187259A4 (de)	2012-10-03	Projektor
DE602008002748D1 (de)	2010-11-04	Linseneinführsystem
DE602008000004D1 (de)	2009-05-20	Linseneinführsystem
BRPI0810633A2 (pt)	2014-11-04	Refrigerador
BRPI0818796A2 (pt)	2015-04-22	Refrigerador
EP2128984A4 (de)	2013-01-16	Gleichrichter
EP2225510A4 (de)	2016-12-07	Kühlvorrichtung
EP2177220A4 (de)	2013-09-11	Gel mit pirfenidon
EP2079772A4 (de)	2012-04-04	Polyharnstoffkleber
EP2233861A4 (de)	2012-08-22	Kühlvorrichtung
BRPI0915099A2 (pt)	2015-08-11	Antioxidante altamente eficaz à base de trealulose.
BRPI0813810A2 (pt)	2015-01-06	Composição de adjuvante à base de óleo
FI20075497L (fi)	2008-12-30	Jäähdytyselementti
DE602008005198D1 (de)	2011-04-14	Kühlvorrichtung
NO20076008L (no)	2009-05-22	Holdeinnretning
DK2235452T3 (da)	2013-10-28	Køleindretning
DE502008001102D1 (de)	2010-09-23	Stativkopf
BRPI0809002A2 (pt)	2014-11-11	Macrolídeos à base de eritromicina
FR2920559B1 (fr)	2011-07-01	Base de donnees distribuee
EP2358251A4 (de)	2013-10-30	Staubbehälter
EP2221062A4 (de)	2011-02-09	Neues adjuvans