EP2199209B1 - Dispositif de remplissage de produits pharmaceutiques dans des récipients d'emballage - Google Patents

Dispositif de remplissage de produits pharmaceutiques dans des récipients d'emballage Download PDF

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Publication number
EP2199209B1
EP2199209B1 EP20080172610 EP08172610A EP2199209B1 EP 2199209 B1 EP2199209 B1 EP 2199209B1 EP 20080172610 EP20080172610 EP 20080172610 EP 08172610 A EP08172610 A EP 08172610A EP 2199209 B1 EP2199209 B1 EP 2199209B1
Authority
EP
European Patent Office
Prior art keywords
voltage
region
pharmaceutical products
guide channel
filling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP20080172610
Other languages
German (de)
English (en)
Other versions
EP2199209A1 (fr
Inventor
Anton Singer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Uhlmann Pac Systeme GmbH and Co KG
Original Assignee
Uhlmann Pac Systeme GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uhlmann Pac Systeme GmbH and Co KG filed Critical Uhlmann Pac Systeme GmbH and Co KG
Priority to EP20080172610 priority Critical patent/EP2199209B1/fr
Priority to US12/638,666 priority patent/US8826631B2/en
Publication of EP2199209A1 publication Critical patent/EP2199209A1/fr
Application granted granted Critical
Publication of EP2199209B1 publication Critical patent/EP2199209B1/fr
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/101—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
    • B65B5/103—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B35/00—Supplying, feeding, arranging or orientating articles to be packaged
    • B65B35/10—Feeding, e.g. conveying, single articles
    • B65B35/12—Feeding, e.g. conveying, single articles by gravity
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B39/00—Nozzles, funnels or guides for introducing articles or materials into containers or wrappers
    • B65B39/007—Guides or funnels for introducing articles into containers or wrappers

Definitions

  • the present invention relates to a device for filling pharmaceutical products into packaging containers.
  • Such a device is for example off US 5,737,902 known.
  • the device described therein comprises a reservoir for pharmaceutical products and a supply device with at least one guide channel for conducting the pharmaceutical products by means of their gravity from the reservoir into the packaging container.
  • the reservoir is usually moved up and down to dispense the pharmaceutical products individually in the guide channel, in which the pharmaceutical products are stacked on each other and gradually discharged down into a filling trough.
  • the filling trough in turn rotates the initially vertically oriented tablets in the direction of a horizontal position and passes the tablets into the packaging containers, for example wells of a blister pack.
  • the guide channel can in the upper area instead of the gradual lowering of the tablets by means of laterally movable stacking floors, as in US 5,737,902 also have elaborate designs for separating and conveying the tablets.
  • certain geometries of the guide channel have been proposed, for example a spiral shape, see EP 1 391 386 A2 , as well as a zigzag shape with three-dimensional component, see EP 1 698 554 A1 ,
  • plastic parts are preferably used to make the device inexpensive and lightweight. This can lead to the generation of unwanted electrostatic charge in some areas, which hinders the function of the filling device.
  • electrostatic charge is generated, whereby an electrostatic field of significant strength can arise, which blocks the pharmaceutical products in the delivery tube.
  • US Pat. No. 2,595,226 discloses a conveyor with means for separating and removing dust particles from tablets. For this purpose, a gas is passed into the conveyor troughs, which was previously ionized by a radioactive substance. This ionized gas neutralizes the static charge of the tablets, which causes the dust particles to adhere to the tablets.
  • the device for filling pharmaceutical products into packaging containers has a storage container for the pharmaceutical products and a supply device with at least one guide channel for conducting the pharmaceutical products by means of their gravity from the storage container into the packaging containers.
  • at least one high-voltage ionizer element supplied with alternating voltage is arranged in the region of the at least one guide channel.
  • the degradation of the electrostatic charge is additionally reinforced by the fact that at least one grounding element is arranged in the region of the at least one guide channel.
  • the degradation of the electrostatic charge is particularly high when the at least one high-voltage ionizer element at least partially surrounds the at least one guide channel.
  • a particularly simple construction which is also applicable to a plurality of guide channels, is present when the at least one high-voltage ionizer element is designed as a plate or strip.
  • the plate or strip extends horizontally so that it can be easily integrated into the device.
  • the grounding element is preferably also designed as a horizontally oriented plate or bar.
  • each guide channel has an upper segment, which is formed by a delivery tube.
  • a high-voltage ionizer element may already be arranged in the region of the at least one delivery tube to provide for the removal of electrostatic charges generated by the up and down movement of the reservoir during insertion of the tablets into the guide channel.
  • the high-voltage ionizer element is arranged in an upper region of the delivery tube and the grounding element is arranged below the high-voltage ionizer element.
  • each guide channel has a lower segment, which is formed by a filling channel.
  • a high-voltage ionizer element in the region of the filling channel, in particular in a lower section of the filling channel with a horizontal component. This ensures that the electrostatic charges generated during the deflection of the tablets within the filling channel are eliminated before the final delivery of the tablets into the packaging containers and thus the filling can take place unhindered.
  • the grounding element is arranged above the high-voltage ionizer element, because this results in a two-sided electric charge destruction, because even the table top over which the packaging container are pulled, acts as a grounded element.
  • Fig. 1 shows a first embodiment of the device according to the invention for filling pharmaceutical products, such as tablets, dragees, capsules, etc. in packaging containers.
  • the device comprises a reservoir 2, in which the pharmaceutical products are stored before filling.
  • the reservoir 2 has one or more trough-shaped recesses which are filled with the pharmaceutical products 4.
  • an opening 6 is arranged, which leads to a feed device with a guide channel 8, which is intended to guide the pharmaceutical products 4 into the packaging containers 10.
  • the packaging containers 10 are usually clocked by means of a transport device (not shown) passed over a table top 12 at the filling station in the direction of arrow A. Likewise, a movement of the packaging container 10 from the drawing level is possible.
  • the packaging container 10 as wells of a Formed blister, which is sealed after filling with the pharmaceutical products 4 with a cover sheet and then punched out of the individual blister packs. But there are also many other applications conceivable that lie outside the pharmaceutical sector.
  • Each guide channel 8 has an upper segment 14 and a lower segment 16 in the illustrated example case.
  • the guide channel 8 may also be designed in one piece in specific embodiments and comprise only one segment.
  • the upper segment 14 is formed in this example as a delivery tube, which projects with its upper portion in an opening 6 of the reservoir 2.
  • the reservoir 2 is in accordance with arrow B in Fig. 2 movable up and down.
  • the left part of the reservoir 2 is in Fig. 2 shown in the raised position, while the right adjoining part of the reservoir 2 is shown in the lowered position.
  • the delivery tubes 14 protrude to different extents into the storage container 2 and thus a supply of individual pharmaceutical products 4 into the delivery tubes 14 is made possible.
  • a multiplicity of delivery tubes 14 are present in a type of matrix arrangement and are connected to the storage container 2 in order to simultaneously transport a plurality of pharmaceutical products 4 to the packaging containers 10 and to be able to fill them with them.
  • both the reservoir 2 and the delivery tube 14 are formed from plastic.
  • electrostatic charges 18 can be generated in the region of the opening 6, which can hinder the introduction of the pharmaceutical products 4 in the delivery tube 14.
  • the device according to the invention has a high-voltage ionizer element 20 in the region of the delivery tube 14, preferably in its upper region. This preferably extends directly below the storage container 2 over its entire width and may preferably be formed as an electrically conductive plate, for example made of metal or metallized plastic, preferably made of stainless steel, which has corresponding openings for the delivery tube 14. Particularly preferred is a direct attachment of the plate at the bottom of the reservoir 2.
  • the high-voltage ionizer 20 is preferably connected to an AC voltage source 22, by means of a flexible conduit which does not hinder the movement of the reservoir 2.
  • the AC voltage source 22 preferably supplies the high-voltage ionizer element 20 with alternating voltage of a frequency of 50 Hz to 60 Hz and a height of 4 kV to 8 kV.
  • the high voltage terminal also includes corresponding high voltage resistors for current limiting and safety warranty.
  • each individual delivery tube 14 with a localized high voltage ionizer element 20 or to provide a different geometric arrangement of the high voltage ionizer elements 20. There are various geometric shapes conceivable here.
  • a grounding element 24 is arranged below the high-voltage ionizer element 20, which is connected to earth 26 via a flexible line and is preferably also formed as a metallically conductive plate with openings for the delivery tube 14. Also, the grounding element can be present in a variety of geometric configurations.
  • the delivery tube 14 may also define a helical guide channel or a zigzag conveying channel with three-dimensional component in addition to the illustrated straight configuration.
  • FIG. 3 and 4 A second alternative embodiment of the present invention is shown.
  • a Hochwoodslonisatorelement 20 and a grounding element 24 are arranged in the lower segment 16 of each filling channel 8.
  • This application is particularly advantageous when the lower segment 16 is designed as a filling channel which has a curvature in its lower region for effecting a rotation of the pharmaceutical products 4.
  • the Gresen 16 which are preferably all integrated into a filling shoe made of plastic, occurs here due to the sliding friction of the pharmaceutical products 4 on the inside of the filling grooves 16 in the curvature region an electrostatic charge, which in turn can hinder the filling of the packaging container 10 with the pharmaceutical products 4.
  • an embodiment of the high-voltage ionizer 20 and the grounding element 24 is preferred as a bar, which may be provided for the Grerinnen 16 recesses in the bar. It can also be provided several strips. There are many possibilities with regard to the geometry of the arrangement. In this embodiment, however, it is advantageous if the high-voltage ionizer element 20 is arranged in a lower region of the filling channels 16 and the grounding element 24 is arranged above the high-voltage ionizer element 20. In this way, a two-sided charge removal is ensured starting from the high-voltage ionizer element up and down.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Basic Packing Technique (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Claims (14)

  1. Dispositif de remplissage de produits pharmaceutiques (4) dans des récipients d'emballage (10), comprenant un réservoir (2) pour les produits pharmaceutiques (4) et un dispositif d'alimentation avec au moins un canal de guidage (8) pour diriger les produits pharmaceutiques, par leur force de gravité, du réservoir (2) dans les récipients d'emballage (10),
    caractérisé en ce que
    au moins un élément ionisateur (20) à haute tension, alimenté en tension alternative, est disposé dans la zone du au moins un canal de guidage (8), et qu'au moins un élément de mise à la terre (24) est disposé dans la zone du au moins un canal de guidage (8).
  2. Dispositif suivant la revendication 1, caractérisé en ce que le au moins un élément ionisateur à haute tension (20) entoure, au moins en partie, le au moins un canal de guidage (8).
  3. Dispositif suivant l'une des revendications 1 et 2, caractérisé en ce que le au moins un élément ionisateur à haute tension (20) est réalisé sous forme de plaque ou de barre.
  4. Dispositif suivant la revendication 3, caractérisé en ce que la plaque ou la barre s'étend horizontalement.
  5. Dispositif suivant l'une des revendications précédentes, caractérisé en ce que le dispositif d'alimentation est formé, au moins en partie, de matière plastique.
  6. Dispositif suivant l'une des revendications précédentes, caractérisé en ce que le au moins un élément de mise à la terre (24) est réalisé sous forme de plaque ou de barre.
  7. Dispositif suivant la revendication 6, caractérisé en ce que la plaque ou la barre s'étend horizontalement.
  8. Dispositif suivant l'une des revendications précédentes, caractérisé en ce que chaque canal de guidage (8) présente un segment supérieur (14), formé par un tube de transport, et que le au moins un élément ionisateur à haute tension (20) est disposé dans la zone du au moins un tube de transport (14).
  9. Dispositif suivant la revendication 8, caractérisé en ce que le au moins un élément de mise à la terre (24) est disposé au-dessous de l'élément ionisateur à haute tension (20).
  10. Dispositif suivant l'une des revendications précédentes, caractérisé en ce que chaque canal de guidage (8) présente un segment inférieur (16), formé par une goulotte de remplissage, et que le au moins un élément ionisateur à haute tension (20) est disposé dans la zone de la au moins une goulotte de remplissage (16).
  11. Dispositif suivant la revendication 10, caractérisé en ce que la au moins une goulotte de remplissage (16) présente dans sa zone inférieure une section avec une composante horizontale pour le remplissage correct des récipients d'emballage (10) en produits pharmaceutiques (4), et que le au moins un élément ionisateur à haute tension (20) est disposé dans la zone de la section pourvue d'une composante horizontale.
  12. Dispositif suivant l'une des revendications 10 et 11, caractérisé en ce que le au moins un élément de mise à la terre (24) est disposé au-dessus de l'élément ionisateur à haute tension (20).
  13. Dispositif suivant l'une des revendications précédentes, caractérisé en ce que chaque canal de guidage (8) présente un segment supérieur (14) et un segment inférieur (16), et qu'au moins un élément ionisateur à haute tension (20) est disposé aussi bien dans la zone du segment supérieur (14) que dans la zone du segment inférieur (16).
  14. Dispositif suivant la revendication 13, caractérisé en ce qu'au moins un élément de mise à la terre (24) est disposé aussi bien dans la zone du segment supérieur (14) que dans la zone du segment inférieur (16).
EP20080172610 2008-12-22 2008-12-22 Dispositif de remplissage de produits pharmaceutiques dans des récipients d'emballage Not-in-force EP2199209B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP20080172610 EP2199209B1 (fr) 2008-12-22 2008-12-22 Dispositif de remplissage de produits pharmaceutiques dans des récipients d'emballage
US12/638,666 US8826631B2 (en) 2008-12-22 2009-12-15 Device for filling packaging receptacles with pharmaceutical products

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20080172610 EP2199209B1 (fr) 2008-12-22 2008-12-22 Dispositif de remplissage de produits pharmaceutiques dans des récipients d'emballage

Publications (2)

Publication Number Publication Date
EP2199209A1 EP2199209A1 (fr) 2010-06-23
EP2199209B1 true EP2199209B1 (fr) 2011-06-15

Family

ID=40589872

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20080172610 Not-in-force EP2199209B1 (fr) 2008-12-22 2008-12-22 Dispositif de remplissage de produits pharmaceutiques dans des récipients d'emballage

Country Status (2)

Country Link
US (1) US8826631B2 (fr)
EP (1) EP2199209B1 (fr)

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ITBO20110708A1 (it) * 2011-12-14 2013-06-15 Marchesini Group Spa Apparato per regolare il rilascio di compresse negli alveoli di un nastro termoformato
US9542533B2 (en) * 2012-09-07 2017-01-10 Miteshkumar Ishwarbhai Patel Medication dosage dispensing system and methods having customization and modification for medicine dispensing configurations
FR3017377B1 (fr) * 2014-02-12 2017-01-13 Stiplastics Dispositif de comptage et de distribution d'objets
PL3018058T3 (pl) * 2014-11-04 2018-02-28 Uhlmann Pac-Systeme Gmbh & Co. Kg Urządzenie napełniające do wstęg blistrów
DE102020111519A1 (de) 2020-04-28 2021-10-28 Jdm Innovation Gmbh Vorrichtung zur Ausgabe von in Blisterbeuteln angeordneten Arzneimitteln und Betriebsverfahren hierfür
US20220380127A1 (en) * 2021-05-27 2022-12-01 Express Scripts Strategic Development, Inc. Pharmaceutical order processing systems and methods
US20240238162A1 (en) * 2021-08-27 2024-07-18 Multiply Labs Inc. System, method, and apparatus facilitating assembly of a capsule

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Also Published As

Publication number Publication date
US20100154354A1 (en) 2010-06-24
EP2199209A1 (fr) 2010-06-23
US8826631B2 (en) 2014-09-09

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