EP2274443A4 - Agents de capture, et procédés et systèmes en rapport pour détecter et/ou trier des cibles - Google Patents

Agents de capture, et procédés et systèmes en rapport pour détecter et/ou trier des cibles

Info

Publication number
EP2274443A4
EP2274443A4 EP09729900A EP09729900A EP2274443A4 EP 2274443 A4 EP2274443 A4 EP 2274443A4 EP 09729900 A EP09729900 A EP 09729900A EP 09729900 A EP09729900 A EP 09729900A EP 2274443 A4 EP2274443 A4 EP 2274443A4
Authority
EP
European Patent Office
Prior art keywords
detecting
methods
systems related
capturing agents
sorting targets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09729900A
Other languages
German (de)
English (en)
Other versions
EP2274443A2 (fr
Inventor
Gabriel A Kwong
Caius G Radu
Antoni Ribas
Owen Witte
James R Heath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology
University of California Berkeley
University of California San Diego UCSD
Original Assignee
California Institute of Technology
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology, University of California Berkeley, University of California San Diego UCSD filed Critical California Institute of Technology
Publication of EP2274443A2 publication Critical patent/EP2274443A2/fr
Publication of EP2274443A4 publication Critical patent/EP2274443A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
EP09729900A 2008-04-09 2009-04-09 Agents de capture, et procédés et systèmes en rapport pour détecter et/ou trier des cibles Withdrawn EP2274443A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12347808P 2008-04-09 2008-04-09
PCT/US2009/040106 WO2009126828A2 (fr) 2008-04-09 2009-04-09 Agents de capture, et procédés et systèmes en rapport pour détecter et/ou trier des cibles

Publications (2)

Publication Number Publication Date
EP2274443A2 EP2274443A2 (fr) 2011-01-19
EP2274443A4 true EP2274443A4 (fr) 2012-03-28

Family

ID=41162620

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09729900A Withdrawn EP2274443A4 (fr) 2008-04-09 2009-04-09 Agents de capture, et procédés et systèmes en rapport pour détecter et/ou trier des cibles

Country Status (6)

Country Link
EP (1) EP2274443A4 (fr)
JP (1) JP2011518553A (fr)
CN (1) CN102112626A (fr)
AU (1) AU2009234162A1 (fr)
CA (1) CA2721085A1 (fr)
WO (1) WO2009126828A2 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2155782A2 (fr) 2007-03-26 2010-02-24 Dako Denmark A/S Complexes peptidiques du cmh et leurs utilisations dans des maladies infectieuses
EP2167537A2 (fr) * 2007-07-03 2010-03-31 Dako Denmark A/S Procedes compiles pour analyser et trier des echantillons
US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
DK2254592T3 (da) 2008-02-28 2019-09-09 Dako Denmark As MHC-multimerer til Borrelia-diagnostik og sygdom
WO2010009735A2 (fr) 2008-07-23 2010-01-28 Dako Denmark A/S Analyse et réparation combinatoires
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease
WO2010037402A1 (fr) 2008-10-02 2010-04-08 Dako Denmark A/S Vaccins moléculaires contre les maladies infectieuses
US20100261292A1 (en) * 2009-04-10 2010-10-14 Meso Scale Technologies, Llc Methods for Conducting Assays
EP4300100A3 (fr) * 2010-10-14 2024-09-04 Meso Scale Technologies, LLC Stockage de réactifs dans un dispositif de dosage
EP2972366B1 (fr) 2013-03-15 2020-06-17 Prognosys Biosciences, Inc. Procédés de détection de liaison peptide/mhc/tcr
CA2951325C (fr) * 2014-06-06 2023-09-12 Herlev Hospital Determination de reconnaissance d'antigene par l'intermediaire d'un marquage par code-barres de multimeres du cmh
WO2015188839A2 (fr) 2014-06-13 2015-12-17 Immudex Aps Détection générale et isolement de cellules spécifiques par liaison de molécules marquées
CN104165990B (zh) * 2014-07-24 2016-11-09 广州万联生物科技有限公司 氯霉素的化学发光酶联免疫检测试剂盒及使用方法
JP6752231B2 (ja) * 2015-06-01 2020-09-09 カリフォルニア インスティテュート オブ テクノロジー 抗原を用いて特異的集団に関してｔ細胞をスクリーニングするための組成物および方法
CN107847544B (zh) * 2015-07-20 2021-10-15 小利兰·斯坦福大学董事会 用多聚体结合试剂检测细胞表型和定量
GB201516568D0 (en) * 2015-09-18 2015-11-04 Univ Birmingham Apparatus and method for improved molecular detection
WO2018183969A1 (fr) * 2017-03-30 2018-10-04 California Institute Of Technology Plate-forme de dosage rapide à code-barres pour l'analyse efficace de molécules candidates et procédés de préparation et d'utilisation de la plate-forme
JP6886854B2 (ja) * 2017-04-13 2021-06-16 シスメックス株式会社 被検物質の情報取得方法
WO2020127222A2 (fr) 2018-12-17 2020-06-25 Immudex Aps Panneau comprenant des multimères de borrelia cmh
AU2020353273A1 (en) * 2019-09-24 2022-03-17 Qiagen Gmbh Multimodal analysis of stabilized cell-containing bodily fluid samples
AU2021349937A1 (en) * 2020-09-24 2023-05-04 University Of Cincinnati Highly chemically stable aptamer sensors
EP4308720B1 (fr) * 2021-03-19 2025-05-07 Paris Sciences Et Lettres Procédés d'analyse sélective de cellules ou d'organites
WO2025081196A1 (fr) * 2023-10-12 2025-04-17 Georgia Tech Research Corporation Isolement sans trace de lymphocytes t spécifiques d'un antigène pour lymphocytes t car afin de produire des lymphocytes t car par tri régulé par adn

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10539561B1 (en) * 2001-08-30 2020-01-21 Customarray, Inc. Enzyme-amplified redox microarray detection process
CN1296492C (zh) * 2004-11-18 2007-01-24 博奥生物有限公司 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法
AU2006272626B2 (en) * 2005-07-26 2010-12-09 Oregon Health & Science University Nanoparticle probes for capture, sorting and placement of targets
US20090017455A1 (en) * 2006-08-02 2009-01-15 Kwong Gabriel A Methods and systems for detecting and/or sorting targets
AU2008276027B2 (en) * 2007-07-16 2014-09-04 California Institute Of Technology Arrays, substrates, devices, methods and systems for detecting target molecules

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BAILEY RYAN C ET AL: "DNA-encoded antibody libraries: A unified platform for multiplexed cell sorting and detection of genes and proteins", February 2007, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, VOL. 129, NR. 7, PAGE(S) 1959-1967, ISSN: 0002-7863, XP002667107 *
DEVIREN GOKHAN ET AL: "Detection of antigen-specific T cells on p/MHC microarrays", January 2007, JOURNAL OF MOLECULAR RECOGNITION, VOL. 20, NR. 1, PAGE(S) 32-38, ISSN: 0952-3499, XP002667108 *
JUNZO NORIMINE ET AL: "Quantitation of Anaplasma marginale major surface protein (MSP)1a and MSP2 epitope-specific CD4+ T lymphocytes using bovine DRB3*1101 and DRB3*1201 tetramers", IMMUNOGENETICS, SPRINGER, BERLIN, DE, vol. 58, no. 9, 19 August 2006 (2006-08-19), pages 726 - 739, XP019421864, ISSN: 1432-1211, DOI: 10.1007/S00251-006-0140-3 *
KWONG GABRIEL A ET AL: "Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells", July 2009, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, VOL. 131, NR. 28, PAGE(S) 9695-9703, ISSN: 0002-7863, XP002667106 *
SANO T ET AL: "A streptavidin mutant containing a cysteine stretch that facilitates production of a variety of specific streptavidin conjugates", BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, vol. 11, no. 2, 1 February 1993 (1993-02-01), pages 201 - 206, XP001526159, ISSN: 0733-222X *
SOEN YOAV ET AL: "Detection and characterization of cellular immune responses using peptide-MHC microarrays.", December 2003, PLOS BIOLOGY, VOL. 1, NR. 3 CITED DECEMBER 31, 2003, PAGE(S) 429-438 URL, XP002667110 *
YANG JUNBAO ET AL: "In vivo biotinylation of the major histocompatibility complex (MHC) class II/peptide complex by coexpression of B irA enzyme for the generation of MHC class II/tetramers", HUMAN IMMUNOLOGY, NEW YORK, NY, US, vol. 65, no. 7, 1 July 2004 (2004-07-01), pages 692 - 699, XP002455388, ISSN: 0198-8859, DOI: 10.1016/J.HUMIMM.2004.04.001 *
YOKOUCHI HIROSHI ET AL: "Tetramer-blocking assay for defining antigen-specific cytotoxic T lymphocytes using peptide-MHC tetramer", February 2006, CANCER SCIENCE, VOL. 97, NR. 2, PAGE(S) 148-154, ISSN: 1347-9032, XP002667109 *

Also Published As

Publication number Publication date
WO2009126828A3 (fr) 2010-03-04
CA2721085A1 (fr) 2009-10-15
CN102112626A (zh) 2011-06-29
AU2009234162A1 (en) 2009-10-15
EP2274443A2 (fr) 2011-01-19
WO2009126828A2 (fr) 2009-10-15
JP2011518553A (ja) 2011-06-30

Similar Documents

Publication Publication Date Title
EP2111248A4 (fr) Système de détection
EP2313847A4 (fr) Procédés et systèmes de traitement de contenu
EP2235662A4 (fr) Capteurs de vision, systèmes et procédés
GB2443055B (en) Fraud detection system
EP2266252A4 (fr) Systèmes et procédés pour mettre en uvre et suivre des tests d'identification
EP2260285A4 (fr) Système de détection de vapeur/particule de trace portatif
EP2478162A4 (fr) Système permettant de monter des objets sur des membranes polymères
EP2615969A4 (fr) Systèmes et procédés permettant de calculer des cartes d'activation
EP2240726A4 (fr) Dispositifs de hottes, procédés, et systèmes dotés de caractéristiques pour améliorer la capture et la contention
TWI348129B (en) Disorder detection device, disorder detection method and disorder detection program
EP2165267A4 (fr) Systèmes et procédés pour intégrer des systèmes de logiciel éducatif
EP2074577A4 (fr) Systèmes et procédés de paiement
EP2350673A4 (fr) Système modulaire pour réaliser des protocoles de laboratoire et procédés associés
EP2089873A4 (fr) Système de detection d'objets
EP2483788A4 (fr) Système de sécurité intégré avec une architecture de traitement en parallèle
EP1996521A4 (fr) Système de récupération
EP2326934A4 (fr) Dispositif de réception d échantillons
EP2106241A4 (fr) Système de surveillance
EP2032499A4 (fr) Système de récipient
EP2350610A4 (fr) Système de détecteurs de corrosion
EP2245606A4 (fr) Système de récupération d'actifs
EP2099366A4 (fr) Système de garrot
FR2923611B1 (fr) Dispositif de detection d'objets,notamment d'objets dangereux
EP2348660A4 (fr) Procédé et dispositif de marquage ou de détection d un signal optique et système de marquage et de détection
SI3660032T1 (sl) Postopki zajemanja in čiščenja beljakovin, izraženih v nesesalskem sistemu

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20101105

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA RS

RIN1 Information on inventor provided before grant (corrected)

Inventor name: HEATH, JAMES, R.

Inventor name: WITTE, OWEN

Inventor name: RIBAS, ANTONI

Inventor name: RADU, CAIUS G.

Inventor name: KWONG, GABRIEL, A.

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 15/10 20060101ALI20120215BHEP

Ipc: G01N 33/68 20060101ALI20120215BHEP

Ipc: G01N 33/53 20060101ALI20120215BHEP

Ipc: C12Q 1/68 20060101AFI20120215BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20120224

17Q First examination report despatched

Effective date: 20131002

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20140213