EP2305576B1 - Emballage pour produits pharmaceutiques ainsi que procédé et dispositif destinés à sa fabrication - Google Patents

Emballage pour produits pharmaceutiques ainsi que procédé et dispositif destinés à sa fabrication Download PDF

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Publication number
EP2305576B1
EP2305576B1 EP09172058A EP09172058A EP2305576B1 EP 2305576 B1 EP2305576 B1 EP 2305576B1 EP 09172058 A EP09172058 A EP 09172058A EP 09172058 A EP09172058 A EP 09172058A EP 2305576 B1 EP2305576 B1 EP 2305576B1
Authority
EP
European Patent Office
Prior art keywords
foil strip
cover foil
cover
webs
strip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP09172058A
Other languages
German (de)
English (en)
Other versions
EP2305576A1 (fr
Inventor
Hans-Werner Bongers-Ambrosius
Uwe Hiller
Reinhold Ruf
Sven Kuhnert
Günter Felk
Lutz Forst
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Uhlmann Pac Systeme GmbH and Co KG
Original Assignee
Uhlmann Pac Systeme GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uhlmann Pac Systeme GmbH and Co KG filed Critical Uhlmann Pac Systeme GmbH and Co KG
Priority to AT09172058T priority Critical patent/ATE549272T1/de
Priority to EP09172058A priority patent/EP2305576B1/fr
Priority to US12/890,972 priority patent/US20110078981A1/en
Publication of EP2305576A1 publication Critical patent/EP2305576A1/fr
Application granted granted Critical
Publication of EP2305576B1 publication Critical patent/EP2305576B1/fr
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/321—Both sheets being recessed
    • B65D75/323—Both sheets being recessed and forming several compartments
    • B65D75/324—Both sheets being recessed and forming several compartments the compartments being interconnected, e.g. by small channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B11/00—Wrapping, e.g. partially or wholly enclosing, articles or quantities of material, in strips, sheets or blanks, of flexible material
    • B65B11/50—Enclosing articles, or quantities of material, by disposing contents between two sheets, e.g. pocketed sheets, and securing their opposed free margins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B47/00—Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved
    • B65B47/04—Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved by application of mechanical pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/321—Both sheets being recessed
    • B65D75/323—Both sheets being recessed and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, spherical or like small articles, e.g. tablets or pills
    • B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
    • B65D83/0463—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container
    • B65D83/0472—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container the band being wound in flat spiral, folded in accordion or the like

Definitions

  • the present invention relates to a packaging for pharmaceutical products and to a method and an apparatus for the production thereof.
  • Pharmaceutical products are filled in a variety of packaging. Particularly common is a type of packaging in which a thermally deformable Bodenfoile is equipped with wells. The wells are then filled with the pharmaceutical products and sealed with a non-stretchable coversheet.
  • a particularly well-known example of such a type of packaging is blister strips for tablets or dragees, but also powdered products, ampoules, etc. are packed in such a way for certain applications.
  • the cups of the bottom film always protrude downwards, the cover sheet is made smooth and is sealed with also smooth webs of the bottom film.
  • CH 680 280 A5 discloses a package for small items.
  • thermoforming foils of thermoplastic material are used to form a lower part and a lower part which are detachably or foldably connected to one another.
  • shallow and deep depressions are formed, which are interconnected by webs.
  • WO 2008/065512 A2 a device which serves for the production of small containers into which liquid or solidifying products after filling can be filled.
  • wells are pressed into two separate mold films and the films are then connected by means of an intermediate foil by hot melting so that the wells are adjacent to each other and thus forms a cavity with two chambers.
  • the resulting small containers can be filled, sealed and cut out.
  • the present invention has for its object to provide a package for pharmaceutical products, with which the possibilities of further use of the packaged pharmaceutical products is extended to additional fields of application, and to provide a method and an apparatus for producing such a package.
  • the packaging for pharmaceutical products comprises a bottom strip with wells which serve to contain the pharmaceutical products and with webs arranged between the cups, and a non-stretchable cover film strip which is sealed to a plurality of webs of the bottom film strip.
  • a plurality of webs of the bottom film strip on a curvature and the cover film strip has the shape of the bulges corresponding, molded into him bulges.
  • the webs of the odenfolienstMails are sealed area of the bulges with the cover film strip, so that even in the edge region of the bowls a secure closure of the same is guaranteed.
  • this embodiment is particularly advantageous because it does not or not only downwardly project the cups formed in the bottom foil, but the intermediate space formed between the bottom of the cup and the cover foil
  • a removal device could be punctured with a straight horizontal movement through the cover sheet and allow access to a powdered pharmaceutical product located in the wells.
  • the bottom foil strip alternately has first and second portions, each first portion being planarized and sealed to the cover film strip, and each second portion having webs with the bumps sealed with a respective bulge of the cover film strip.
  • the provision of the non-stretchable cover film strip preferably comprises the steps of providing a cover film roll, partially unwinding the cover film roll, cutting off, grasping and displacing a cover film strip.
  • the cover film strip is stitched to the bottom film strip after superimposing the formed cover film strip and the bottom film strip and before sealing the cover film strip with a plurality of the webs of the bottom film strip.
  • the device for producing the packaging for pharmaceutical products comprises a forming station for gradually successively forming bulges in a non-stretchable cover film strip; a transport device for superimposing the shaped cover film strip and a bottom film strip, wherein the bottom film strip has cups, which serve to receive the pharmaceutical products, and webs arranged between the cups; and a sealing station for sealing the cover film strip to a plurality of the webs of the bottom film strip; in which
  • the sealing station has two sealing plates which are shaped according to the bulges in the cover foil strip, whereby the sealing of the cover foil strip with the bottom foil strip also takes place in the region of bulges of the bottom foil lining, which correspond to the shape of the notches in the cover foil strip
  • the apparatus has an unwinding device for partially unwinding a cover film roll, also a cutting device for cutting a cover film strip and a feed device for gripping and moving the cover film strip.
  • the forming station has two molds which are movable towards and away from each other, wherein one of the two molds has punches which act successively on the cover film strip, and the other of the two molds of the shape of the stamp has corresponding recordings.
  • the stamps are graded arranged in series with respect to their altitude and pneumatically biased.
  • the non-stretchable cover sheet of, for example, aluminum which is neither thermoformable nor deformable by deep drawing in one piece, be provided with bulges, and this even in a mechanically relatively simple manner.
  • the mold with the receptacles may have a suction device for the molded cover film strip and may be part of the transport device, which is rotatable about a vertical axis arranged outside the mold.
  • the device For temporarily adhering the cover film strip to the bottom film strip prior to its actual sealing, the device has an attachment device, which is arranged upstream of the sealing station and has a plurality of heating pins.
  • FIG. 1 and 2 illustrated example of a packaging for pharmaceutical products according to the invention comprises a bottom foil strip 2 and a cover foil strip 4.
  • Fig. 1 For example, the bottom foil strip 2 and the cover foil strip 4 are shown separately in a state they occupy before sealing.
  • Fig. 2 the sealed final state of the packaging is shown.
  • the bottom foil strip 2 comprises a plurality of wells 6, which serve for receiving pharmaceutical products.
  • the cups 6 can accommodate tablets, dragees and liquid substances, but preferably powdery substances.
  • a plurality of webs 8 of the bottom foil strip 2 is arranged between the cups 6 of the bottom foil strip 2, a plurality of webs 8 of the bottom foil strip 2 is arranged.
  • a plurality of webs 8 of the bottom foil strip 2 have a curvature 10 which projects upwards.
  • the bottom foil strip 2 has alternating first sections 12 and second sections 14. The first sections 12 are each formed flat and have no cups 6, while the second sections 14 have webs 8 with the bulges 10.
  • the bottom foil strip 2 consists of a thermoplastically deformable material and is produced by means of known molding methods, but with special shaping tools.
  • the cover film strip 4, however, consists of a non-stretchable material, in which debits 16 are nevertheless formed, which correspond to the shape of the bulges 10 in the bottom foil strip 2.
  • the material of the bottom foil strip 2 is usually PVC, PVC / PVDC or PVC / ACLAR, but other materials may also be used, for example aluminum composite foils, COC, PS, PP or PET.
  • the cover film strip 4 is usually formed of hard aluminum or aluminum defined hardness, but may also consist of other non-stretchable materials, for example made of paper laminated aluminum foil.
  • the sealing between the bottom foil strip 2 and the cover foil strip 4 is preferably carried out on all webs 8 of the bottom foil strip 2.
  • the flat webs 8 of the bottom foil strip 2 are sealed with corresponding flat portions of the cover film strip 4, but also the webs 8 of the bottom film strip 2 in the area the bulges 10 are sealed to the cover film strip 4 in the region of its bulges 16. This ensures a secure closure of the cups 6 in the bottom foil strip 2.
  • the cups 6 may extend over a wider area in the cambers 10, the bottom of the cups 6 may protrude further down (readily beyond the plane formed by the planar first portions 12), various other camber patterns may be present in the bottom film strip 2 It is important in each case that in general a certain number of webs 8 of the bottom foil strip 2 has a curvature 10 at all and the cover foil strip 4 has the shape of the bulges 10 corresponding bulges 16 formed in it.
  • Fig. 3 and 4 is an exemplary embodiment of an apparatus for producing a packaging for pharmaceutical products according to Fig. 1 and 2 shown. It comprises an unwinding device 18 for partially unwinding a cover film roll 20, a cutting device 22 for cutting a cover film strip 4 and a feed device 23 for gripping and shifting the cover film strip 4.
  • it has a forming station 24, a transport device 26 for superimposing the shaped cover film strip 4 and of the bottom foil strip 2, an attachment device 28 for provisionally adhering the cover film strip 4 to the bottom foil strip 2, and a sealing station 30 arranged downstream of the tack device 28 (only in FIG Fig. 3 ) for sealing the cover film strip 4 with a plurality of webs 8 of the bottom film strip 2.
  • the feed device 23 for the cover film strip 4 from the cutting device 22 to the forming station 24 can also be configured in any desired manner, but a gripping or clamping mechanism at the front edge of the cover film strip 4 is preferred.
  • the forming station 24 consists, as usual, of a first mold 32 and a second mold 34 which are movable towards and away from each other. Details are below with reference to Fig. 5 and 6 explained in more detail.
  • the transport device 26 comprises two parts.
  • the first part serves to transport the cover film strip 4 from the forming station 24 to the second part, which transports the superposed pairs of cover film strips 4 and bottom film strips 2 to the sealing station 30.
  • the first part of the transport device 26 is designed to be rotatable about a rotation axis Z.
  • a shaft 36 is rotatably mounted in a bearing device 38 and rotatable by a drive, not shown, by 180 °.
  • a drive not shown
  • At the lower end of the shaft 36 extending in a horizontal orientation right and left of the shaft 36 mirror images first molds 32. This ensures that each one first mold 32 remains at the location of the molding station 24, while the other first mold 32 offset by 180 ° thereto is arranged and serves for passing the cover film strip 4.
  • the two first molds 32 exchange their place.
  • a suction device with vacuum suction openings is preferably included, which hold the molded cover film strip 4 on the first mold 32, so that even during rotation through 180 ° about the axis Z ensures a secure adhesion of the cover film strip 4 on the first mold 32 is.
  • the first part of the transport device 26 can also be designed in various other ways.
  • a gripping device or a pick-and-place device can remove the shaped cover film strip 4 from the forming station 24 and transport it in the direction of the sealing station 30.
  • the shaft 36 may be mounted at its lower end in the bearing device 38. Many other deviations are also conceivable for the skilled person.
  • the transport device 26 is also a feed device conceivable, for example by means of a gripping arm or by means of a moving vacuum suction belt.
  • the transport device 26 consists of only one part and deposits the cover film strip 4 directly on the already placed in the sealing station 30 bottom film strip 2.
  • the attachment device 28 will be described below with reference to FIGS. 7 and 8 explained in more detail.
  • the sealing station 30 is in Fig. 9 shown in more detail and has two sealing plates 40 which are formed according to the bulges 16 in the cover film strip 4 and are movable toward and away from each other.
  • the first mold 32 in this case comprises receptacles 42, which correspond to the shape of the bulges 16, which are to be formed in the cover film strip 4.
  • the second molding tool 34 comprises stamps 44, which are complementary to the shape of the receptacles 42.
  • the punches are designed roll-shaped, but they can take any shape adapted to the desired shape of the bulges 16 in the cover film strip 4, assume.
  • the punches are mounted on lateral guides 46 upwardly and downwardly displaceable and preferably acted upon in its central region via single-acting pneumatic cylinder 48.
  • the punches 44 are arranged in series with respect to their altitude in series and pneumatically biased by the pneumatic cylinder 48.
  • a contact will take place between the foremost punch 44 and the foremost receptacle 42 and thus a bulge 16 is formed in the cover foil strip 4, while between the remaining punches 44 and the remaining receptacles 42 no contact is made yet, ie in the rear area of the cover film strip 4 is not yet clamped.
  • a bulge 16 is successively formed in the non-stretchable cover film strip 4 after the next, until even the last, lowest-lying punch 44 has come into contact with the corresponding receptacle 42.
  • Between the individual molding processes of adjacent bulges 16 usually take one to two seconds.
  • the stepped height position of the individual punches 44 can be realized, for example, by the fact that insertion discs 50 can be provided for limiting the stroke in the region of the lateral guides 46.
  • the punch 44 act one by one on the cover film strip 4.
  • the punch 44 can be individually actively moved up, but this means a greater effort than the mechanically predetermined gradation of the altitude of the punch 44, as it is realized in the illustrated example.
  • One end of the cover film strip 4 must therefore be free to move, so that material of the cover film strip 4 can be tightened when creating a bulge 16.
  • FIGS. 7 and 8 the attachment device 28 is shown in detail.
  • an attaching device 28 which punctually arrests the cover film strip 4 and the bottom film strip 2.
  • the attachment device 28 has for this purpose Heating pins 52 which are arranged in a predetermined pattern.
  • the heating pins 52 each act on flat webs 8 in the region of the first portions 12 of the bottom film strip 2 and corresponding portions of the cover film strip 4.
  • the tacking device 28 can be moved via a lifting arm 54 in the vertical direction.
  • the heating pins 52 can preferably be mounted on spring elements 56 and pass through passage openings 58 in the first mold 32.
  • the method according to the invention for producing a packaging for pharmaceutical products thus proceeds in the illustrated embodiment as follows: First, the cover film roll 20 is unwound from the unwinding device 18 and a cover film strip 4 is cut off by means of the cutting device 22. Subsequently, the cover film strip 4 is gripped by means of the feed device 23 and moved into the forming station 24. Alternatively, another cover film strip 4 is provided.
  • step by step one after the other, shaping of the desired bulges takes place in the cover film strip 4.
  • the cover film strip 4 After the molding of the protrusions 16 in the cover film strip 4, this is transported further by means of the transport device 26 and laid one above the other with a likewise preformed bottom film strip 2.
  • the molded cover film strip 4 is sucked for this purpose on the first mold 32 and rotated by the rotatable shaft 36 by 180 ° about the axis Z.
  • the tack device 28 can be actuated.
  • the lifting arm 54 is lowered in the illustrated embodiment, so that the heating pins 52 pass through the passage openings 58 in the first mold 32 and arrest the cover film strip 4 at certain points with the bottom film strip 2.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Plastic Fillers For Packaging (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Claims (12)

  1. Emballage pour produits pharmaceutiques, comprenant
    un ruban de feuille de fond (2) avec des alvéoles (6), qui servent à recevoir des produits pharmaceutiques, et des traverses (8) disposées entre les alvéoles (6) ; et
    un ruban de feuille de couverture (4) non extensible, scellé avec une multiplicité de traverses (8) du ruban de feuille de fond,
    caractérisé en ce que
    plusieurs traverses (8) du ruban de feuille de fond (2) présentent un cintrage (10) et le ruban de feuille de couverture (4) présente des courbures (16), correspondant à la forme des cintrages (10) et moulées dans ce dernier, et que les traverses (8) du ruban de feuille de fond (2) sont scellées avec le ruban de feuille de couverture (4) dans la zone des cintrages (10).
  2. Emballage suivant la revendication 1, caractérisé en ce que le ruban de feuille de fond (2) présente en alternance des premières sections (12) et des secondes sections (14), chaque première section (12) ayant une réalisation plane et étant scellée avec le ruban de feuille de couverture (4), et chaque seconde section (14) présentant des traverses (8) avec les cintrages (10), qui sont scellés respectivement avec une courbure (16) du ruban de feuille de couverture (4).
  3. Emballage suivant la revendication 2, caractérisé en ce que les alvéoles (6) sont réalisées dans la zone des secondes sections (14) du ruban de feuille de fond (2).
  4. Procédé de fabrication d'un emballage pour produits pharmaceutiques, comprenant les étapes suivantes :
    - préparation d'un ruban de feuille de fond (2) avec des alvéoles (6), qui servent à recevoir des produits pharmaceutiques, et avec des traverses (8) disposées entre les alvéoles (6), plusieurs traverses (8) du ruban de feuille de fond (2) présentant un cintrage (10) ;
    - préparation d'un ruban de feuille de couverture (4) non extensible ;
    - moulage individuel successif, par étapes, de courbures (16) correspondant à la forme des cintrages (10), dans le ruban de feuille de couverture (4) ;
    - superposition du ruban de feuille de couverture moulé (4) et du ruban de feuille de fond (2) ; et
    - scellement du ruban de feuille de couverture (4) avec une multiplicité des traverses (8) du ruban de feuille de fond (2), le scellement du ruban de feuille de couverture (4) avec une multiplicité des traverses (8) du ruban de feuille de fond (2) étant également assuré dans la zone des cintrages (10).
  5. Procédé suivant la revendication 4, caractérisé en ce que la préparation du ruban de feuille de couverture (4) non extensible comprend les étapes de préparer un rouleau de feuille de couverture (20), de dérouler en partie le rouleau de feuille de couverture (20), de découper un ruban de feuille de couverture (4), de le saisir et de le déplacer.
  6. Procédé suivant l'une des revendications 4 et 5, caractérisé en ce que le ruban de feuille de couverture (4) est fixé ponctuellement sur le ruban de feuille de fond (2), après la superposition du ruban de feuille de couverture (4) moulé et du ruban de feuille de fond (2) et avant le scellement du ruban de feuille de couverture (4) avec une multiplicité des traverses (8) du ruban de feuille de fond (2).
  7. Dispositif de fabrication d'un emballage pour produits pharmaceutiques, comprenant :
    - un poste de moulage (24) pour le moulage individuel successif, par étapes, de courbures (16) dans un ruban de feuille de couverture (4) non extensible ;
    - un dispositif de transport (26) pour la superposition du ruban de feuille de couverture moulé (4) et d'un ruban de feuille de fond (2), le ruban de feuille de fond (2) présentant des alvéoles (6), qui servent à recevoir des produits pharmaceutiques, et des traverses (8) disposées entre les alvéoles (6) ; et
    - un poste de scellage (30) pour le scellement du ruban de feuille de couverture (4) avec une multiplicité des traverses (8) du ruban de feuille de fond (2) ;
    caractérisé en ce que
    le poste de scellage (30) présente deux plaques de scellage (40), qui sont formées en conformité avec les courbures (16) du ruban de feuille de couverture (4), le scellement du ruban de feuille de couverture (4) avec le ruban de feuille de fond (2) s'effectuant de ce fait également dans la zone des cintrages (10) du ruban de feuille de fond (2), qui correspondent à la forme des courbures (16) dans le ruban de feuille de couverture (4).
  8. Dispositif suivant la revendication 7, caractérisé en ce qu'il présente un dispositif de déroulement (18) pour le déroulement partiel d'un rouleau de feuille de couverture (20), un dispositif de coupe (22) pour découper un ruban de feuille de couverture (4), et un dispositif d'avance (23) pour la saisie et le déplacement du ruban de feuille de couverture (4).
  9. Dispositif suivant l'une des revendications 7 et 8, caractérisé en ce que le poste de moulage (24) pour le ruban de feuille de couverture (4) présente deux outils de moulage (32, 34), qui sont mobiles l'un vers l'autre et à l'écart l'un de l'autre, un second (34) des deux outils de moulage présentant des pistons (44), qui agissent les uns après les autres sur le ruban de feuille de couverture (4), et un premier (32) des deux outils de moulage présentant des logements (42) correspondants à la forme des pistons (44).
  10. Dispositif suivant l'une des revendications 7 à 9, caractérisé en ce que les pistons (44) sont disposés en rangée étagée quant à leur position en hauteur et sont précontraints par voie pneumatique.
  11. Dispositif suivant l'une des revendications 7 à 10, caractérisé en ce que l'outil de moulage (32) avec les logements (42) présente un dispositif d'aspiration pour le ruban de feuille de couverture (4) moulé et fait partie du dispositif de transport (26), qui peut tourner autour d'un axe (Z) vertical disposé à l'extérieur de l'outil de moulage (32).
  12. Dispositif suivant l'une des revendications 7 à 11, caractérisé en ce qu'il présente un dispositif de fixation (28) pour la fixation provisoire du ruban de feuille de couverture (4) sur le ruban de feuille de fond (2), lequel dispositif est disposé en amont du poste de scellage (30) et présente plusieurs broches de chauffage (52).
EP09172058A 2009-10-02 2009-10-02 Emballage pour produits pharmaceutiques ainsi que procédé et dispositif destinés à sa fabrication Not-in-force EP2305576B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AT09172058T ATE549272T1 (de) 2009-10-02 2009-10-02 Verpackung für pharmazeutische produkte sowie verfahren und vorrichtung zu ihrer herstellung
EP09172058A EP2305576B1 (fr) 2009-10-02 2009-10-02 Emballage pour produits pharmaceutiques ainsi que procédé et dispositif destinés à sa fabrication
US12/890,972 US20110078981A1 (en) 2009-10-02 2010-09-27 Packaging for pharmaceutical products and method and device for its production

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Application Number Priority Date Filing Date Title
EP09172058A EP2305576B1 (fr) 2009-10-02 2009-10-02 Emballage pour produits pharmaceutiques ainsi que procédé et dispositif destinés à sa fabrication

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EP2305576A1 EP2305576A1 (fr) 2011-04-06
EP2305576B1 true EP2305576B1 (fr) 2012-03-14

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US (1) US20110078981A1 (fr)
EP (1) EP2305576B1 (fr)
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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2896573B1 (fr) * 2014-01-21 2018-03-14 MULTIVAC Sepp Haggenmüller SE & Co. KG Thermoformeuse avec station de formage du film supérieur et méthode correpondante
DE102014106427A1 (de) * 2014-05-08 2015-11-12 Technische Universität Dresden Verfahren und Vorrichtung zur Herstellung von Formteilen aus einer Faserwerkstoffbahn
EP3135602A1 (fr) * 2015-08-25 2017-03-01 Bayer Pharma Aktiengesellschaft Blister
DE102016203145B4 (de) * 2016-02-26 2022-09-15 Deutsches Institut Für Lebensmitteltechnik E.V. Vorrichtung und Verfahren zur Herstellung verpackter Gegenstände
EP4606714A1 (fr) * 2024-02-23 2025-08-27 Harro Höfliger Verpackungsmaschinen GmbH Dispositif et procédé pour sceller une partie de cathéter dans un manchon en feuille

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US4001075A (en) * 1974-11-20 1977-01-04 Marathon Cheese Corporation Seal for packages capable of thermoplastic sealing and means for effecting such sealing
US4884718A (en) * 1984-12-20 1989-12-05 Dennison Manufacturing Company Container with a releasable hinged closure panel and a fixed closure panel
US4776150A (en) * 1986-12-31 1988-10-11 Siegel Harold B Sealing apparatus
US4988004A (en) * 1987-08-21 1991-01-29 Intini Thomas D Bend 'n peel child resistant/tamper evident blister package
CH680280A5 (en) * 1990-04-18 1992-07-31 Pyramid Innovation Ag Small piece goods package - comprises top and bottom portions with alternating deep and shallow recesses and offset
US5172812A (en) * 1992-01-23 1992-12-22 Rexham Corporation Child-resistant paperboard blister package and method of making the same
US5644895A (en) * 1995-05-01 1997-07-08 Johnson & Johnson Vision Products, Inc. Packaging arrangement
DE29623683U1 (de) * 1996-04-09 1999-04-15 BP Chemicals PlasTec GmbH, 89165 Dietenheim Verpackung
DE29714246U1 (de) * 1997-08-08 1998-12-10 THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte, 82229 Seefeld Vorrichtung zum Lagern und Auftragen einer fließfähigen Substanz
US6269671B1 (en) * 1998-09-16 2001-08-07 Alusuisse Technology & Management Ltd. Process for manufacturing shaped packaging
EP1487716A4 (fr) * 2002-03-26 2008-05-21 Glaxo Group Ltd Procede de formation d'ensemble stratifie et produits formes selon ce procede
US7097037B1 (en) * 2002-07-17 2006-08-29 Keffeler Mark G Cover assembly for a medication dispenser
US7377277B2 (en) * 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
US7377394B2 (en) * 2004-07-20 2008-05-27 Fisher Clinical Services Blister pack having a tether ultrasonically welded through a lidding and into a rib
ITMO20060395A1 (it) * 2006-11-29 2008-05-30 Sarong Spa Contenitore, apparato e metoo per la sua produzione
US20090045210A1 (en) * 2007-08-18 2009-02-19 Tilton Christopher R Pliable ground calcium carbonates storage articles and method of making same
SG185933A1 (en) * 2007-10-31 2012-12-28 Novartis Ag Packaging seal plate having a shaped face
US20110203965A1 (en) * 2010-02-22 2011-08-25 Richard Sandra L Food storage container

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ATE549272T1 (de) 2012-03-15
US20110078981A1 (en) 2011-04-07
EP2305576A1 (fr) 2011-04-06

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