EP2306902A4 - Procédés d'identification de modulateurs de canaux ioniques - Google Patents

Procédés d'identification de modulateurs de canaux ioniques

Info

Publication number
EP2306902A4
EP2306902A4 EP09794839A EP09794839A EP2306902A4 EP 2306902 A4 EP2306902 A4 EP 2306902A4 EP 09794839 A EP09794839 A EP 09794839A EP 09794839 A EP09794839 A EP 09794839A EP 2306902 A4 EP2306902 A4 EP 2306902A4
Authority
EP
European Patent Office
Prior art keywords
methods
ion channel
channel modulators
identifying ion
identifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09794839A
Other languages
German (de)
English (en)
Other versions
EP2306902A1 (fr
Inventor
Lance G Laing
Rick Wagner
Rafael Fernandez
Alexander Yuzakov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
X Body Inc
Original Assignee
SRU Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/171,475 external-priority patent/US9778267B2/en
Priority claimed from US12/335,433 external-priority patent/US9134307B2/en
Application filed by SRU Biosystems Inc filed Critical SRU Biosystems Inc
Publication of EP2306902A1 publication Critical patent/EP2306902A1/fr
Publication of EP2306902A4 publication Critical patent/EP2306902A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • AIDS & HIV (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP09794839A 2008-07-11 2009-01-08 Procédés d'identification de modulateurs de canaux ioniques Withdrawn EP2306902A4 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12/171,475 US9778267B2 (en) 2007-07-11 2008-07-11 Methods for identifying modulators of ion channels
PCT/US2008/069752 WO2009009718A1 (fr) 2007-07-11 2008-07-11 Procédés d'identification de modulateurs de canaux ioniques
US12/335,433 US9134307B2 (en) 2007-07-11 2008-12-15 Method for determining ion channel modulating properties of a test reagent
PCT/US2009/030412 WO2010005600A1 (fr) 2008-07-11 2009-01-08 Procédés d'identification de modulateurs de canaux ioniques

Publications (2)

Publication Number Publication Date
EP2306902A1 EP2306902A1 (fr) 2011-04-13
EP2306902A4 true EP2306902A4 (fr) 2011-08-10

Family

ID=41507363

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09794839A Withdrawn EP2306902A4 (fr) 2008-07-11 2009-01-08 Procédés d'identification de modulateurs de canaux ioniques

Country Status (6)

Country Link
EP (1) EP2306902A4 (fr)
JP (1) JP2011527573A (fr)
CN (1) CN102149327A (fr)
AU (1) AU2009269037A1 (fr)
CA (1) CA2730415A1 (fr)
WO (1) WO2010005600A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8111401B2 (en) 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US7524625B2 (en) 2000-10-30 2009-04-28 Sru Biosystems, Inc. Real time binding analysis of antigens on a biosensor surface
US7575939B2 (en) 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7371562B2 (en) 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7118710B2 (en) 2000-10-30 2006-10-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7927822B2 (en) 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
US7309614B1 (en) 2002-12-04 2007-12-18 Sru Biosystems, Inc. Self-referencing biodetection method and patterned bioassays
US8298780B2 (en) 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
AU2008274978A1 (en) * 2007-07-11 2009-01-15 Sru Biosystems, Inc. Methods of identifying modulators of ion channels
US8257936B2 (en) 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
JP2013523095A (ja) * 2010-03-26 2013-06-17 エックス−ボディ インコーポレイテッド 化合物ライブラリーをスクリーニングするための人工多能性細胞および他の細胞の使用法
CN106537149A (zh) * 2014-04-01 2017-03-22 宝洁公司 用于筛选色氨酸通道的方法
CN107596341B (zh) * 2017-08-23 2020-08-28 清华大学 L型电压门控钙通道特异性多肽类激动剂和抑制剂

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020028480A1 (en) * 2000-07-10 2002-03-07 Maher Michael P. High throughput method and system for screening candidate compounds for activity against target ion channels
US20040132214A1 (en) * 2000-10-30 2004-07-08 Sru Biosystems, Llc Label-free methods for performing assays using a colorimetric resonant optical biosensor
WO2007064702A1 (fr) * 2005-11-30 2007-06-07 Sru Biosystems, Inc. Analyse en temps reel de la liaison d'antigenes sur une surface de biocapteur
WO2009009718A1 (fr) * 2007-07-11 2009-01-15 Sru Biosystems, Inc. Procédés d'identification de modulateurs de canaux ioniques
WO2010075033A1 (fr) * 2008-12-15 2010-07-01 Sru Biosystems, Inc. Procédés de détection de changements dans des cellules

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7575939B2 (en) * 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7927822B2 (en) * 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
CN101300489A (zh) * 2005-11-03 2008-11-05 红点生物公司 Trpm5离子通道的高通量筛选实验

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020028480A1 (en) * 2000-07-10 2002-03-07 Maher Michael P. High throughput method and system for screening candidate compounds for activity against target ion channels
US20040191757A1 (en) * 2000-07-10 2004-09-30 Maher Michael P. High throughput method and system for screening candidate compounds for activity against target ion channels
US20040132214A1 (en) * 2000-10-30 2004-07-08 Sru Biosystems, Llc Label-free methods for performing assays using a colorimetric resonant optical biosensor
WO2007064702A1 (fr) * 2005-11-30 2007-06-07 Sru Biosystems, Inc. Analyse en temps reel de la liaison d'antigenes sur une surface de biocapteur
WO2009009718A1 (fr) * 2007-07-11 2009-01-15 Sru Biosystems, Inc. Procédés d'identification de modulateurs de canaux ioniques
WO2010075033A1 (fr) * 2008-12-15 2010-07-01 Sru Biosystems, Inc. Procédés de détection de changements dans des cellules

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2010005600A1 *

Also Published As

Publication number Publication date
CA2730415A1 (fr) 2010-01-14
CN102149327A (zh) 2011-08-10
JP2011527573A (ja) 2011-11-04
WO2010005600A1 (fr) 2010-01-14
AU2009269037A1 (en) 2010-01-14
EP2306902A1 (fr) 2011-04-13

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