PL2376648T3 - Markery epigenetyczne do identyfikacji CD3-pozytywnych limfocytów T - Google Patents

Markery epigenetyczne do identyfikacji CD3-pozytywnych limfocytów T

Info

Publication number
PL2376648T3
PL2376648T3 PL09771304T PL09771304T PL2376648T3 PL 2376648 T3 PL2376648 T3 PL 2376648T3 PL 09771304 T PL09771304 T PL 09771304T PL 09771304 T PL09771304 T PL 09771304T PL 2376648 T3 PL2376648 T3 PL 2376648T3
Authority
PL
Poland
Prior art keywords
lymphocytes
identification
positive
epigenetic markers
epigenetic
Prior art date
Application number
PL09771304T
Other languages
English (en)
Inventor
Sven Olek
Ivana Türbachova
Original Assignee
Epiontis Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epiontis Gmbh filed Critical Epiontis Gmbh
Publication of PL2376648T3 publication Critical patent/PL2376648T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL09771304T 2008-12-16 2009-12-08 Markery epigenetyczne do identyfikacji CD3-pozytywnych limfocytów T PL2376648T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20080021838 EP2199411B1 (en) 2008-12-16 2008-12-16 Epigenetic markers for the identification of CD3 positive T-lymphocytes
EP09771304.4A EP2376648B1 (en) 2008-12-16 2009-12-08 Epigenetic markers for the identification of cd3 positive t-lymphocytes

Publications (1)

Publication Number Publication Date
PL2376648T3 true PL2376648T3 (pl) 2017-05-31

Family

ID=40428037

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09771304T PL2376648T3 (pl) 2008-12-16 2009-12-08 Markery epigenetyczne do identyfikacji CD3-pozytywnych limfocytów T

Country Status (8)

Country Link
US (1) US20120107810A1 (pl)
EP (2) EP2199411B1 (pl)
JP (1) JP2012511917A (pl)
CA (1) CA2747312C (pl)
DK (2) DK2199411T3 (pl)
ES (1) ES2606350T3 (pl)
PL (1) PL2376648T3 (pl)
WO (1) WO2010069499A2 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170233807A1 (en) 2008-12-16 2017-08-17 Epiontis Gmbh Epigenetic Markers for the Identification of Blood Sub-cells of Type 1
WO2012021867A2 (en) * 2010-08-13 2012-02-16 The Johns Hopkins University A comprehensive methylome map of myeloid and lymphoid commitment from hematopoietic progenitors
EP2625288B1 (en) 2010-10-08 2016-05-25 Epiontis GmbH Method for determining cancer patient survival based on analyzing tumor-infiltrating overall t-lymphocytes
US20130296328A1 (en) * 2011-01-20 2013-11-07 Université Libre de Bruxelles Epigenetic portraits of human breast cancers
WO2012162660A2 (en) * 2011-05-25 2012-11-29 Brown University Methods using dna methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies
US20140178348A1 (en) 2011-05-25 2014-06-26 The Regents Of The University Of California Methods using DNA methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies
WO2013135454A1 (en) * 2012-03-12 2013-09-19 Epiontis Gmbh Epigenetic marker for the identification of cd3cd4 positive t lymphocytes
GB201221133D0 (en) * 2012-11-23 2013-01-09 Epiontis Gmbh Epigenetic method for the identification of subpopulations of CD8 and T lympocytes, in particular CD8 alpha and beta T lymphocytes
EP2986735B1 (en) * 2013-04-19 2019-03-06 Epiontis GmbH Method for identifying the quantitative composition of blood cells in a sample
EP3360971B1 (en) * 2017-02-09 2026-05-20 Precision for Medicine GmbH IMPROVED METHOD FOR COUNTING EPIGENETIC IMMUNE CELLS
EP3382033B1 (en) * 2017-03-30 2020-08-05 Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen Method for determining blood counts based on dna methylation
DE102017125019B4 (de) * 2017-10-25 2019-10-17 Epiontis Gmbh PDCD1 als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere PD1+ Zellen
DE102018116353B4 (de) * 2018-07-05 2020-06-10 Epiontis Gmbh Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening
CN116949156B (zh) * 2023-09-19 2023-12-08 美迪西普亚医药科技(上海)有限公司 一种基于核酸变体的通用型检测人t细胞的分析方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002171973A (ja) * 2000-12-07 2002-06-18 Univ Tokyo Dnaメチル化パターンによる細胞の同定法
WO2004050706A2 (en) 2002-12-03 2004-06-17 Medical Research Council Regulatory t-cells
ATE508207T1 (de) 2006-02-28 2011-05-15 Charite Universitaetsmedizin Nachweis und qualitätskontrolle von regulator-t- zellen mittels dna-methylierungsanalyse des foxp3-gens

Also Published As

Publication number Publication date
HK1163189A1 (zh) 2012-09-07
US20120107810A1 (en) 2012-05-03
EP2199411B1 (en) 2015-05-06
EP2376648A2 (en) 2011-10-19
EP2376648B1 (en) 2016-09-14
WO2010069499A3 (en) 2010-08-26
JP2012511917A (ja) 2012-05-31
CA2747312C (en) 2018-11-06
DK2376648T3 (da) 2017-01-02
WO2010069499A2 (en) 2010-06-24
DK2199411T3 (en) 2015-08-03
EP2199411A1 (en) 2010-06-23
CA2747312A1 (en) 2010-06-24
ES2606350T3 (es) 2017-03-23

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