EP2326764A2 - Utilisation de fibres lyocell et articles contenant des fibres lyocell - Google Patents

Utilisation de fibres lyocell et articles contenant des fibres lyocell

Info

Publication number
EP2326764A2
EP2326764A2 EP09783225A EP09783225A EP2326764A2 EP 2326764 A2 EP2326764 A2 EP 2326764A2 EP 09783225 A EP09783225 A EP 09783225A EP 09783225 A EP09783225 A EP 09783225A EP 2326764 A2 EP2326764 A2 EP 2326764A2
Authority
EP
European Patent Office
Prior art keywords
wound
lyocell fibers
fibers
textile
unmodified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09783225A
Other languages
German (de)
English (en)
Inventor
Sigrid Redlinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lenzing AG
Original Assignee
Lenzing AG
Chemiefaser Lenzing AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT0147108A external-priority patent/AT507386A1/de
Application filed by Lenzing AG, Chemiefaser Lenzing AG filed Critical Lenzing AG
Publication of EP2326764A2 publication Critical patent/EP2326764A2/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives

Definitions

  • the invention relates to the use of lyocell fibers, a yarn containing lyocell fibers, a textile fabric containing lyocell fibers, and a textile article containing lyocell fibers.
  • lyocell has been assigned by BISFA (The International Bureau for the Standardization of Man Made Fibers) and stands for cellulose fibers which are produced from solutions of cellulose in an organic solvent, tertiary amine oxides, in particular N-methyl Morpholine N-oxide (NMMO) is used, for example, a process for producing lyocell fibers is described in US-A 4,246,221.
  • BISFA The International Bureau for the Standardization of Man Made Fibers
  • NMMO N-methyl Morpholine N-oxide
  • the present invention relates to the use of lyocell fibers in wound treatment products.
  • the expert generally distinguishes three phases of physiological wound healing:
  • the primary goal of the treatment is the elimination of cell debris and microorganisms as well as the formation of a provisional matrix
  • the primary target is to form granulation tissue and reepithelialize to form a temporary barrier
  • the present invention is a dry wound treatment product which is currently primarily cotton
  • essentially untreated products such as bleached cotton
  • the quickest way to heal wounds would be theoretically (in a germ-free, moist environment) without any support from a bandage, etc.
  • WO 2005/026424 A1 describes the use of lyocell fibers for the treatment of textile contact sensitivity or skin diseases, in particular xerosis, atopic eczema or psoriasis.
  • Austrian Patent Application A 1471/2008 describes chitosan-modified cellulose fibers and their use as wound-healing products.
  • significantly more proliferative cells were wound on the wound edge and tendentially more proliferative cells in the regenerating epidermis of chitosan-treated lyocell fibers than untreated lyocell fiber and cotton.
  • DE 100 07 794 A1, DE 100 37 983 A1 and EP 1 354 914 describe polymer compositions which each comprise a biodegradable polymer and various modifying agents, e.g. Including algae, alkaloids and herbs.
  • the polymer composition may be in the form of fibers, e.g. from a mixture of the modifying agent with a solution of cellulose in a tertiary amine oxide.
  • non-modified lyocell fibers ie lyocell fibers that do not have modifying agents such as chitosan, algae, alkaloids carboxymethylated form
  • modifying agents such as chitosan, algae, alkaloids carboxymethylated form
  • the present invention relates to unmodified lyocell fibers, a yarn containing unmodified lyocell fibers, a fabric containing unmodified lyocell fibers, or a textile article containing unmodified lyocell fibers, each for specific use as a product for wound treatment, in particular for dry wound treatment.
  • the present invention relates to a dry wound treatment product characterized in that it contains unmodified lyocell fibers in its intended area to be applied to the wound.
  • the present invention therefore generally relates to the use of unmodified lyocell fibers for the manufacture of a wound treatment product.
  • Unmodified lyocell fibers have been found to significantly accelerate wound healing compared to other unmodified products heretofore used as a substrate in dry wound treatment (ie, products containing no drugs or wound healing promoting agents), particularly when compared to bleached cotton.
  • CMC fibers or fibers modified with chitosan represents a very large cost advantage.
  • the yarn used according to the invention, the textile fabric or the textile article are each substantially completely composed of non-modified Lyocell fibers.
  • the yarn used according to the invention, the textile fabric or the textile article may contain foreign fibers in an amount of up to 90%, preferably 10 to 50%.
  • unmodified lyocell fibers are understood to be various fibers, e.g. Cotton, polyester, viscose and modal fibers or modified lyocell fibers. Unmodified fibers are also preferably used as foreign fibers, ie fibers which are not modified or derivatized with active substances, etc.
  • a textile fabric for specific use according to the invention may be present in particular in the form of a woven, knitted, knitted or nonwoven fabric.
  • the invention relates to a product for wound treatment, in particular for dry wound treatment, which is characterized in that it contains non-modified Lyocell fibers in its area intended for laying on the wound.
  • the product according to the invention may in particular be selected from the group consisting of patches, wound dressings, bandages, bandages, gypsum underlay fabrics, underwear, pajamas for atopic dermatitis, orthopedic support bandages, support bandages, wound gauze, compresses, gauze, compression bandages, compression stockings and tubular bandages.
  • the wound treatment product according to the invention is preferably characterized in that the proportion of unmodified lyocell fibers in the area intended to rest on the wound is at least 10%, preferably 50% to 100%, particularly preferably 90% to 100%.
  • the remaining fibers in the area intended to rest on the wound can be foreign fibers as above, in particular non-modified foreign fibers.
  • the lyocell fiber used according to the invention can be present in a tanning range which is customary for textile products or nonwovens or in a customary cutting length.
  • the fiber may have a denier of 1.3 dtex and a cut length of 38 mm.
  • the fiber can be used in bleached form. Examples
  • Punctures with a diameter of 6 mm were taken from the plicae of washed and sterilized pig ears. From the center of the punches, the epidermis and the upper Dennis were removed in a range of 3 mm. Subsequently, the models were incubated in Air-Liquid Interphase at 37 ° C, 5% CO 2 and saturated humidity in the dermatological clinic. Immediately after generation of the models, 5 ⁇ l of PBS were applied to the control. For the other samples, 4 mm diameter platelets were removed from the knits using Biopsy punches and placed on the wounds.
  • the models were after 48 h snap frozen and at -8O 0 C.
  • the models were completely embedded in tissue freezing medium (Leica, Nussloch) and made with the cryostat 6 micron thin sections. It was ensured that you were in the middle of each model.
  • the sections were placed on Superfrost slides, air-dried 10 min cold acetone fixed and stored at -8O 0 C in -20 0 C.
  • HE staining (general morphology): All models were stained with hematoxylin / eosin (HE) (2 sections each). The staining was evaluated on a Leica light microscope DM LS and an Olympus Camedia digital camera. Evaluation parameters: Wound healing progress and morphology - Good / bad preservation of the wound margin (maceration)
  • the evaluation of the wound healing progress is based on the PBS control in order to take into account the wound healing potential of the respective pig, which is determined by the values obtained with PBS (physiological phosphate buffer).
  • PBS physiological phosphate buffer
  • the wound healing progress achieved only with PBS is thus the highest value (ideal wound healing) in the skin organ culture model that can be achieved (100% or value 1).
  • Sample 1 Polyester Fiber (Tergal PES)
  • Sample 2 Unmodified Lyocell Fiber
  • Sample 3 Bleached Cotton
  • Sample 4 PBS Control

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Yarns And Mechanical Finishing Of Yarns Or Ropes (AREA)

Abstract

L'invention concerne l'utilisation de fibres lyocell non modifiées, d'un fil contenant des fibres lyocell non modifiées, d'une surface textile contenant des fibres lyocell non modifiées, ou d'un article textile contenant des fibres lyocell non modifiées, en tant que produit destiné notamment au traitement de plaies à sec.
EP09783225A 2008-09-22 2009-09-21 Utilisation de fibres lyocell et articles contenant des fibres lyocell Withdrawn EP2326764A2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0147108A AT507386A1 (de) 2008-09-22 2008-09-22 Verfahren zur behandlung cellulosischer formkörper
AT0175008A AT507387A1 (de) 2008-09-22 2008-11-11 Verwendung von lyocellfasern sowie lyocellfasern enthaltenden artikeln
PCT/EP2009/062177 WO2010031862A2 (fr) 2008-09-22 2009-09-21 Utilisation de fibres lyocell et articles contenant des fibres lyocell

Publications (1)

Publication Number Publication Date
EP2326764A2 true EP2326764A2 (fr) 2011-06-01

Family

ID=42039948

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09783225A Withdrawn EP2326764A2 (fr) 2008-09-22 2009-09-21 Utilisation de fibres lyocell et articles contenant des fibres lyocell

Country Status (6)

Country Link
US (1) US20110172624A1 (fr)
EP (1) EP2326764A2 (fr)
JP (1) JP2012502710A (fr)
CN (1) CN102159764A (fr)
AT (1) AT507387A1 (fr)
WO (1) WO2010031862A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2368532A1 (fr) 2010-03-25 2011-09-28 Ganzoni & Cie AG Textiles de compression contenant des fibres revêtues de chitosan
EP2540263A1 (fr) 2011-06-29 2013-01-02 Sigvaris Inc. Vêtements à compression graduée
CN104764736B (zh) * 2015-03-30 2018-01-12 河北出入境检验检疫局检验检疫技术中心 莱赛尔a100的鉴别方法及其应用
CN104764872A (zh) * 2015-03-30 2015-07-08 河北出入境检验检疫局检验检疫技术中心 莱赛尔纤维的鉴别方法及其应用
CN106436024B (zh) * 2016-09-21 2018-09-07 天津工业大学 一种远红外面膜基布的制备方法
US20200000640A1 (en) * 2018-06-29 2020-01-02 Milliken & Company Multi-Layer Wound Care Device Having Absorption and Fluid Transfer Properties

Family Cites Families (28)

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US4246221A (en) * 1979-03-02 1981-01-20 Akzona Incorporated Process for shaped cellulose article prepared from a solution containing cellulose dissolved in a tertiary amine N-oxide solvent
US4309534A (en) * 1979-02-15 1982-01-05 University Of Delaware Renatured chitosan and process of making same
US4946870A (en) * 1986-06-06 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Delivery systems for pharmaceutical or therapeutic actives
US4929722A (en) * 1986-06-06 1990-05-29 Union Carbide Chemicals And Plastics Company Inc. Acid decrystallization of aminopolysaccharides and derivatives thereof
JPH0768648B2 (ja) * 1991-02-20 1995-07-26 富士紡績株式会社 改質セルロース再生繊維
DE4127604A1 (de) * 1991-08-21 1993-02-25 Hoechst Ag Schlauchfoermige nahrungsmittelhuelle mit verbesserten hafteigenschaften gegenueber dem fuellgut
ATA53792A (de) * 1992-03-17 1995-02-15 Chemiefaser Lenzing Ag Verfahren zur herstellung cellulosischer formkörper, vorrichtung zur durchführung des verfahrens sowie verwendung einer spinnvorrichtung
FI924408A0 (fi) * 1992-09-30 1992-09-30 Novasso Oy Modifierade viskosfibrer och foerfarande foer dess framstaellning.
US5900479A (en) * 1995-05-05 1999-05-04 Virginia Tech Intellectual Properties, Inc. Chitin-based coatings
AT403296B (de) * 1995-08-11 1997-12-29 Chemiefaser Lenzing Ag Verfahren zur herstellung eines celluloseformkörpers
DE19607953A1 (de) * 1996-03-01 1997-09-04 Kalle Nalo Gmbh Nach dem Aminoxidverfahren hergestellte Nahrungsmittelhüllen auf Cellulosebasis
JP2822174B2 (ja) * 1996-03-01 1998-11-11 オーミケンシ株式会社 キチンキトサン繊維及び構造体の製造法
AT2256U1 (de) * 1997-10-15 1998-07-27 Chemiefaser Lenzing Ag Verfahren zur behandlung von cellulosischen formkörpern
GB9812329D0 (en) * 1998-06-08 1998-08-05 Courtaulds Plc Yarns and wound dressings containing the same
DE10007794A1 (de) * 2000-02-21 2001-06-28 Zimmer Ag Polymerzusammensetzung und daraus hergestellter Formkörper
DE10009248C2 (de) * 2000-02-28 2002-06-27 Freudenberg Carl Kg Medizinisches Verbandsmaterial
US6835678B2 (en) * 2000-05-04 2004-12-28 Kimberly-Clark Worldwide, Inc. Ion sensitive, water-dispersible fabrics, a method of making same and items using same
US7048771B2 (en) * 2001-10-22 2006-05-23 University Of California Dyeing textiles using nanoparticles
JP3742027B2 (ja) * 2002-04-08 2006-02-01 Necビューテクノロジー株式会社 投射映像の歪補正方法、歪補正プログラム及び投射型映像表示装置
AT411769B (de) * 2002-07-12 2004-05-25 Chemiefaser Lenzing Ag Verfahren zur herstellung cellulosischer formkörper
GB0303295D0 (en) * 2003-02-13 2003-03-19 Lohmann Gmbh & Co Kg Filamentary nonwoven bandage fabric
AT504730A1 (de) * 2003-09-16 2008-07-15 Chemiefaser Lenzing Ag Verwendung von lyocellfasern sowie lyocellfasern enthaltenden artikeln
US20050102815A1 (en) * 2003-11-03 2005-05-19 L&L Products, Inc. Reinforced members formed with absorbent mediums
GB0513555D0 (en) * 2005-07-01 2005-08-10 Bristol Myers Squibb Co Carboxymethylated cellulosic wound dressing garment
DK1759676T3 (da) * 2005-09-06 2014-01-13 Sigvaris Man Ag Strikket bandage
WO2007066339A1 (fr) * 2005-12-07 2007-06-14 Ramot At Tel Aviv University Ltd. Structures composites pour l’administration de médicaments
AT503803B1 (de) * 2006-06-14 2008-01-15 Chemiefaser Lenzing Ag Lyocell-stapelfaser
ES2446246T3 (es) * 2006-08-04 2014-03-06 Kuraray Co., Ltd. Material textil no tejido estirable y bandas

Non-Patent Citations (1)

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Title
See references of WO2010031862A2 *

Also Published As

Publication number Publication date
JP2012502710A (ja) 2012-02-02
US20110172624A1 (en) 2011-07-14
WO2010031862A3 (fr) 2010-11-18
AT507387A1 (de) 2010-04-15
WO2010031862A9 (fr) 2010-06-10
WO2010031862A2 (fr) 2010-03-25
CN102159764A (zh) 2011-08-17

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