EP2362909A4 - Gènes mammaliens intervenant dans une infection - Google Patents

Gènes mammaliens intervenant dans une infection

Info

Publication number
EP2362909A4
EP2362909A4 EP09818408A EP09818408A EP2362909A4 EP 2362909 A4 EP2362909 A4 EP 2362909A4 EP 09818408 A EP09818408 A EP 09818408A EP 09818408 A EP09818408 A EP 09818408A EP 2362909 A4 EP2362909 A4 EP 2362909A4
Authority
EP
European Patent Office
Prior art keywords
miracle
genes
infections
infections involved
involved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09818408A
Other languages
German (de)
English (en)
Other versions
EP2362909A2 (fr
Inventor
Donald Rubin
Thomas Hodge
James Murray
Natalie Mcdonald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zirus Inc
Vanderbilt University
Original Assignee
Zirus Inc
Vanderbilt University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zirus Inc, Vanderbilt University filed Critical Zirus Inc
Publication of EP2362909A2 publication Critical patent/EP2362909A2/fr
Publication of EP2362909A4 publication Critical patent/EP2362909A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y601/00Ligases forming carbon-oxygen bonds (6.1)
    • C12Y601/01Ligases forming aminoacyl-tRNA and related compounds (6.1.1)
    • C12Y601/01005Isoleucine-tRNA ligase (6.1.1.5)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00Production
    • C12N2330/30Production chemically synthesised
    • C12N2330/31Libraries, arrays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP09818408A 2008-09-30 2009-09-30 Gènes mammaliens intervenant dans une infection Withdrawn EP2362909A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19477408P 2008-09-30 2008-09-30
US19577008P 2008-10-09 2008-10-09
PCT/US2009/058947 WO2010039778A2 (fr) 2008-09-30 2009-09-30 Gènes mammaliens intervenant dans une infection

Publications (2)

Publication Number Publication Date
EP2362909A2 EP2362909A2 (fr) 2011-09-07
EP2362909A4 true EP2362909A4 (fr) 2012-10-10

Family

ID=42074170

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09818408A Withdrawn EP2362909A4 (fr) 2008-09-30 2009-09-30 Gènes mammaliens intervenant dans une infection

Country Status (2)

Country Link
EP (1) EP2362909A4 (fr)
WO (1) WO2010039778A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101913232B1 (ko) * 2010-10-27 2018-10-30 큐알엔에이, 인크. 인터페론-관련된 발달성 조절물질 1 (ifrd1)에 대한 자연 안티센스 전사체의 저해에 의한 ifrd1 관련된 질환의 치료
WO2013110120A1 (fr) * 2012-01-24 2013-08-01 Inter-K Pty Limited Agents peptidiques utilisés en thérapie anticancéreuse
FR2987627B1 (fr) * 2012-03-05 2016-03-18 Splicos Utilisation de rbm39 comme biomarqueur
CA2877948C (fr) 2012-07-02 2019-07-30 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Paramyxovirus et methodes d'utilisation
JP6707028B2 (ja) * 2013-12-09 2020-06-10 ベイラー カレッジ オブ メディスンBaylor College Of Medicine 心筋細胞新生におけるhippo及びジストロフィン複合体シグナル伝達
WO2019119036A1 (fr) * 2017-12-19 2019-06-27 Benitec Biopharma Limited Cellules déficientes en cd70, et procédés et réactifs pour leur production
CN108707607A (zh) * 2018-06-08 2018-10-26 邵玉芹 一种能特异性检测ev71病毒的适配体及试剂盒
WO2020239949A1 (fr) * 2019-05-29 2020-12-03 Centre National De La Recherche Scientifique Procédé d'identification d'activités enzymatiques de l'ubiquitine et de type ubiquitine
CN113274510B (zh) * 2021-04-29 2022-05-13 山东农业大学 抑制j亚群禽白血病病毒复制的组合物及其应用
EP4627084A1 (fr) * 2022-12-01 2025-10-08 Camp4 Therapeutics Corporation Modulation de la transcription du gène syngap1 à l'aide d'oligonucléotides antisens ciblant les arn régulateurs
CN118576714B (zh) * 2024-05-27 2025-08-26 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) Herc4基因或蛋白为靶点在筛选抑制口蹄疫病毒复制的药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040018505A1 (en) * 2001-06-29 2004-01-29 Lee Ernestine A. Aminoacyl trna synthetases
US20060079474A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Analogs of tRNA synthetase fragments and uses thereof
WO2007084488A2 (fr) * 2006-01-13 2007-07-26 Vanderbilt University Adam10 et ses utilisations dans l'infection

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CLAYTON F ET AL: "Gp120-induced Bob/GPR15 activation: a possible cause of human immunodeficiency virus enteropathy.", THE AMERICAN JOURNAL OF PATHOLOGY, vol. 159, no. 5, November 2001 (2001-11-01), pages 1933 - 1939, XP002682331, ISSN: 0002-9440 *
D. MCDONALD: "Visualization of the intracellular behavior of HIV in living cells", THE JOURNAL OF CELL BIOLOGY, vol. 159, no. 3, 11 November 2002 (2002-11-11), pages 441 - 452, XP055036240, ISSN: 0021-9525, DOI: 10.1083/jcb.200203150 *
KENNEY SHANNON: "Theodore E. Woodward Award: development of novel, EBV-targeted therapies for EBV-positive tumors.", TRANSACTIONS OF THE AMERICAN CLINICAL AND CLIMATOLOGICAL ASSOCIATION, vol. 117, 2006, pages 55 - 74, XP002682332, ISSN: 0065-7778 *
W. ZHANG ET AL: "RNA Interference Inhibits Respiratory Syncytial Virus Replication and Disease Pathogenesis without Inhibiting Priming of the Memory Immune Response", JOURNAL OF VIROLOGY, vol. 82, no. 24, 25 September 2008 (2008-09-25), pages 12221 - 12231, XP055036354, ISSN: 0022-538X, DOI: 10.1128/JVI.01557-08 *

Also Published As

Publication number Publication date
WO2010039778A2 (fr) 2010-04-08
EP2362909A2 (fr) 2011-09-07
WO2010039778A3 (fr) 2010-09-16

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Ipc: A61K 48/00 20060101ALI20120828BHEP

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