EP2542249A4 - Verfahren und zusammensetzungen zur unterstützung von gewebeintegration und inokulation von transplantiertem gewebe und transplantiertem gezüchtetem penisgewebe mit stromazellen aus fettgewebe - Google Patents
Verfahren und zusammensetzungen zur unterstützung von gewebeintegration und inokulation von transplantiertem gewebe und transplantiertem gezüchtetem penisgewebe mit stromazellen aus fettgewebeInfo
- Publication number
- EP2542249A4 EP2542249A4 EP20100847139 EP10847139A EP2542249A4 EP 2542249 A4 EP2542249 A4 EP 2542249A4 EP 20100847139 EP20100847139 EP 20100847139 EP 10847139 A EP10847139 A EP 10847139A EP 2542249 A4 EP2542249 A4 EP 2542249A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- tissue
- transplanted
- inosculation
- compositions
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000010354 integration Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 210000002536 stromal cell Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/33—Fibroblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15164924.1A EP2926821B1 (de) | 2010-03-05 | 2010-03-05 | Zusammensetzungen zur unterstützung von gewebeintegration und inokulation von transplantiertem gewebe und transplantiertem gezüchtetem penisgewebe mit stromazellen aus fettgewebe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2010/026407 WO2011109026A1 (en) | 2010-03-05 | 2010-03-05 | Methods and compositions to support tissue integration and inosculation of transplanted tissue and transplanted engineered penile tissue with adipose stromal cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP15164924.1A Division EP2926821B1 (de) | 2010-03-05 | 2010-03-05 | Zusammensetzungen zur unterstützung von gewebeintegration und inokulation von transplantiertem gewebe und transplantiertem gezüchtetem penisgewebe mit stromazellen aus fettgewebe |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2542249A1 EP2542249A1 (de) | 2013-01-09 |
| EP2542249A4 true EP2542249A4 (de) | 2013-08-07 |
Family
ID=44542472
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20100847139 Ceased EP2542249A4 (de) | 2010-03-05 | 2010-03-05 | Verfahren und zusammensetzungen zur unterstützung von gewebeintegration und inokulation von transplantiertem gewebe und transplantiertem gezüchtetem penisgewebe mit stromazellen aus fettgewebe |
| EP15164924.1A Active EP2926821B1 (de) | 2010-03-05 | 2010-03-05 | Zusammensetzungen zur unterstützung von gewebeintegration und inokulation von transplantiertem gewebe und transplantiertem gezüchtetem penisgewebe mit stromazellen aus fettgewebe |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP15164924.1A Active EP2926821B1 (de) | 2010-03-05 | 2010-03-05 | Zusammensetzungen zur unterstützung von gewebeintegration und inokulation von transplantiertem gewebe und transplantiertem gezüchtetem penisgewebe mit stromazellen aus fettgewebe |
Country Status (2)
| Country | Link |
|---|---|
| EP (2) | EP2542249A4 (de) |
| WO (1) | WO2011109026A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10751374B2 (en) | 2012-01-30 | 2020-08-25 | Michael P. Zahalsky | Methods and compositions for treatment of penile defects |
| US20180028575A1 (en) | 2012-01-30 | 2018-02-01 | Michael Zahalsky | Methods and compositions for treatment of penile defects |
| US20150231182A1 (en) * | 2012-09-07 | 2015-08-20 | University Of Louisville Research Foundation, Inc. | Cell systems and methods for delivering disease-specific therapies |
| US10398558B2 (en) | 2016-10-07 | 2019-09-03 | Coloplast A/S | Method of surgically providing a trans-male patient with a neopenis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6514292B1 (en) * | 1998-05-21 | 2003-02-04 | Children's Medical Center Corporation | Corporal tissue penile reconstruction |
| EP1908820A1 (de) * | 2006-10-06 | 2008-04-09 | Stichting Voor De Technische Wetenschappen | Anreicherung von Stammzellen und/oder Vorläuferzeller |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3949073A (en) | 1974-11-18 | 1976-04-06 | The Board Of Trustees Of Leland Stanford Junior University | Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US4820626A (en) | 1985-06-06 | 1989-04-11 | Thomas Jefferson University | Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself |
| US5035708A (en) | 1985-06-06 | 1991-07-30 | Thomas Jefferson University | Endothelial cell procurement and deposition kit |
| US5863531A (en) | 1986-04-18 | 1999-01-26 | Advanced Tissue Sciences, Inc. | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework |
| US5266480A (en) | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
| US4963489A (en) | 1987-04-14 | 1990-10-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
| US5902741A (en) | 1986-04-18 | 1999-05-11 | Advanced Tissue Sciences, Inc. | Three-dimensional cartilage cultures |
| US5510254A (en) | 1986-04-18 | 1996-04-23 | Advanced Tissue Sciences, Inc. | Three dimensional cell and tissue culture system |
| US5041138A (en) | 1986-11-20 | 1991-08-20 | Massachusetts Institute Of Technology | Neomorphogenesis of cartilage in vivo from cell culture |
| US4883755A (en) | 1987-10-28 | 1989-11-28 | Thomas Jefferson University | Method of reendothelializing vascular linings |
| WO1994000484A1 (en) | 1992-06-22 | 1994-01-06 | Young Henry E | Scar inhibitory factor and use thereof |
| US5672346A (en) | 1992-07-27 | 1997-09-30 | Indiana University Foundation | Human stem cell compositions and methods |
| US5957972A (en) | 1992-09-29 | 1999-09-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Implants possessing a surface of endothelial cells genetically-modified to inhibit intimal thickening |
| KR950703640A (ko) | 1992-10-09 | 1995-09-20 | 가일 케이,나우톤. | 간 보존 세포(liver reserve cells) |
| US5514378A (en) | 1993-02-01 | 1996-05-07 | Massachusetts Institute Of Technology | Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures |
| US5709854A (en) | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| US6121042A (en) | 1995-04-27 | 2000-09-19 | Advanced Tissue Sciences, Inc. | Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs |
| US5792603A (en) | 1995-04-27 | 1998-08-11 | Advanced Tissue Sciences, Inc. | Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts |
| WO1996039992A1 (en) | 1995-06-07 | 1996-12-19 | Advanced Tissue Sciences, Inc. | Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing replacement cartilage tissue constructs |
| US5842477A (en) | 1996-02-21 | 1998-12-01 | Advanced Tissue Sciences, Inc. | Method for repairing cartilage |
| US5763267A (en) | 1996-04-16 | 1998-06-09 | Advanced Tissue Sciences | Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures |
| US5827729A (en) | 1996-04-23 | 1998-10-27 | Advanced Tissue Sciences | Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue |
| US6224893B1 (en) | 1997-04-11 | 2001-05-01 | Massachusetts Institute Of Technology | Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering |
| US5786207A (en) | 1997-05-28 | 1998-07-28 | University Of Pittsburgh | Tissue dissociating system and method |
| AU729377B2 (en) | 1997-10-23 | 2001-02-01 | Asterias Biotherapeutics, Inc. | Methods and materials for the growth of primate-derived primordial stem cells in feeder-free culture |
| US20030082152A1 (en) | 1999-03-10 | 2003-05-01 | Hedrick Marc H. | Adipose-derived stem cells and lattices |
| BR0008552A (pt) | 1999-03-10 | 2002-05-07 | Univ Pittsburgh | Células tronco e redes derivadas de tecido adiposo |
| US7270996B2 (en) | 2000-10-02 | 2007-09-18 | Cannon Thomas F | Automated bioculture and bioculture experiments system |
| US7052829B2 (en) | 2001-03-30 | 2006-05-30 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Prevascularized constructs for implantation to provide blood perfusion |
| WO2002078439A2 (en) * | 2001-03-30 | 2002-10-10 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Prevascularized constructs for implantation to provide blood perfusion |
| WO2007030652A2 (en) | 2005-09-08 | 2007-03-15 | University Of Virginia Patent Foundation | Methods and compositions for growing adipose stem cells |
| BRPI0619794B8 (pt) | 2005-12-13 | 2022-06-14 | Univ Kyoto | Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| US20090227032A1 (en) | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
| WO2008088882A2 (en) | 2007-01-19 | 2008-07-24 | The J. David Gladstone Institutes | Methods of generating cardiomyocytes |
| US20090304654A1 (en) * | 2008-04-30 | 2009-12-10 | Regents Of The University Of California | Methods for isolating adipose-derived stem cells and therapeutic use thereof |
-
2010
- 2010-03-05 EP EP20100847139 patent/EP2542249A4/de not_active Ceased
- 2010-03-05 WO PCT/US2010/026407 patent/WO2011109026A1/en not_active Ceased
- 2010-03-05 EP EP15164924.1A patent/EP2926821B1/de active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6514292B1 (en) * | 1998-05-21 | 2003-02-04 | Children's Medical Center Corporation | Corporal tissue penile reconstruction |
| EP1908820A1 (de) * | 2006-10-06 | 2008-04-09 | Stichting Voor De Technische Wetenschappen | Anreicherung von Stammzellen und/oder Vorläuferzeller |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO2011109026A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011109026A1 (en) | 2011-09-09 |
| EP2926821B1 (de) | 2019-12-25 |
| EP2542249A1 (de) | 2013-01-09 |
| EP2926821A1 (de) | 2015-10-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20121004 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR |
|
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20130708 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 35/12 20060101ALI20130702BHEP Ipc: A61K 35/48 20060101ALI20130702BHEP Ipc: A61K 35/28 20060101AFI20130702BHEP Ipc: A61K 35/44 20060101ALI20130702BHEP |
|
| 17Q | First examination report despatched |
Effective date: 20140429 |
|
| RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: VOSSMAN, ERIK Inventor name: WILLIAMS, STUART, K. Inventor name: HOYING, JAMES BEATTY Inventor name: PAEK, HYUN, JOON |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R003 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
| 18R | Application refused |
Effective date: 20150525 |