EP3145584A4 - Systèmes et procédés de stimulation du nerf vague - Google Patents

Systèmes et procédés de stimulation du nerf vague Download PDF

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Publication number
EP3145584A4
EP3145584A4 EP15795617.8A EP15795617A EP3145584A4 EP 3145584 A4 EP3145584 A4 EP 3145584A4 EP 15795617 A EP15795617 A EP 15795617A EP 3145584 A4 EP3145584 A4 EP 3145584A4
Authority
EP
European Patent Office
Prior art keywords
systems
methods
nerve stimulation
vagal nerve
vagal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP15795617.8A
Other languages
German (de)
English (en)
Other versions
EP3145584A1 (fr
EP3145584B1 (fr
Inventor
Bruce J. Simon
Joseph P. Errico
John T. Raffle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ElectroCore Inc
Original Assignee
ElectroCore Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/286,412 external-priority patent/US9566426B2/en
Application filed by ElectroCore Inc filed Critical ElectroCore Inc
Publication of EP3145584A1 publication Critical patent/EP3145584A1/fr
Publication of EP3145584A4 publication Critical patent/EP3145584A4/fr
Application granted granted Critical
Publication of EP3145584B1 publication Critical patent/EP3145584B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/025—Digital circuitry features of electrotherapy devices, e.g. memory, clocks, processors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0492—Patch electrodes
    • A61N1/0496—Patch electrodes characterised by using specific chemical compositions, e.g. hydrogel compositions, adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/004—Magnetotherapy specially adapted for a specific therapy
    • A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/004—Magnetotherapy specially adapted for a specific therapy
    • A61N2/008—Magnetotherapy specially adapted for a specific therapy for pain treatment or analgesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Social Psychology (AREA)
  • Neurosurgery (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Electrotherapy Devices (AREA)
EP15795617.8A 2014-05-23 2015-05-22 Systèmes de stimulation du nerf vague Active EP3145584B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/286,412 US9566426B2 (en) 2011-08-31 2014-05-23 Systems and methods for vagal nerve stimulation
PCT/US2015/032144 WO2015179744A1 (fr) 2014-05-23 2015-05-22 Systèmes et procédés de stimulation du nerf vague

Publications (3)

Publication Number Publication Date
EP3145584A1 EP3145584A1 (fr) 2017-03-29
EP3145584A4 true EP3145584A4 (fr) 2018-01-24
EP3145584B1 EP3145584B1 (fr) 2022-02-16

Family

ID=54554822

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15795617.8A Active EP3145584B1 (fr) 2014-05-23 2015-05-22 Systèmes de stimulation du nerf vague

Country Status (5)

Country Link
EP (1) EP3145584B1 (fr)
JP (1) JP6981752B2 (fr)
KR (1) KR102382416B1 (fr)
CN (1) CN106794347B (fr)
WO (1) WO2015179744A1 (fr)

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AU2014207265B2 (en) 2013-01-21 2017-04-20 Cala Health, Inc. Devices and methods for controlling tremor
US12453853B2 (en) 2013-01-21 2025-10-28 Cala Health, Inc. Multi-modal stimulation for treating tremor
AU2015271774B2 (en) 2014-06-02 2020-04-16 Cala Health, Inc. Systems and methods for peripheral nerve stimulation to treat tremor
KR102427652B1 (ko) 2015-03-30 2022-08-01 세팔리 테크놀로지 에스피알엘 삼차 신경의 경피 전기 자극을 위한 장치
EP4342516A3 (fr) 2015-06-10 2024-07-10 Cala Health, Inc. Systèmes et procédés de stimulation du nerf périphérique pour traiter un tremblement avec des unités de traitement et de surveillance détachables
EP3328277A4 (fr) 2015-07-31 2019-03-06 Cala Health, Inc. Systèmes, dispositifs et procédé permettant le traitement de l'arthrose
US10603482B2 (en) 2015-09-23 2020-03-31 Cala Health, Inc. Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors
AU2017211048B2 (en) 2016-01-21 2022-03-10 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
JP7133543B2 (ja) 2016-08-25 2022-09-08 カラ ヘルス，インコーポレイテッド 末梢神経刺激による心機能不全の治療のためのシステムおよび方法
JP7094528B2 (ja) * 2016-10-18 2022-07-04 フィンガルリンク株式会社 電気的刺激装置
US11331480B2 (en) 2017-04-03 2022-05-17 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
KR101964918B1 (ko) * 2017-10-17 2019-04-02 연세대학교 산학협력단 심장 전압 지도와 전위 활성화 지도에 기반한 심장 모델 생성 장치 및 방법
US12465260B2 (en) 2018-02-09 2025-11-11 Presidio Medical, Inc. Systems and methods for cardiac conduction block
US11813459B2 (en) * 2018-02-20 2023-11-14 Presidio Medical, Inc. Methods and systems for nerve conduction block
KR102118530B1 (ko) * 2018-02-23 2020-06-03 김민규 펄스 자기장을 이용한 미주신경 자극 방법 및 장치
CN112930209B (zh) 2018-10-15 2024-10-15 诺沃库勒有限责任公司 生成遍及大脑具有高均匀性的肿瘤治疗场(ttfields)的装置和方法
EP3870272B1 (fr) * 2018-10-24 2025-07-02 Cala Health, Inc. Stimulation nerveuse pour le traitement de la migraine et d'autres états de céphalée
AU2020272128B9 (en) * 2019-04-12 2025-11-20 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
CA3145807A1 (fr) * 2019-07-03 2021-01-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Blocage neuronal par une stimulation electrique a basse frequence superieure au seuil
US12251560B1 (en) 2019-08-13 2025-03-18 Cala Health, Inc. Connection quality determination for wearable neurostimulation systems
WO2021074455A1 (fr) * 2019-10-18 2021-04-22 Stimit Ag Dispositif de stimulation et son utilisation
WO2021102448A1 (fr) 2019-11-24 2021-05-27 Presidio Medical, Inc. Systèmes de moteurs de stimulation et de génération d'impulsions
WO2021154736A1 (fr) * 2020-01-27 2021-08-05 Alternating Current Treatment Therapy Medical Inc. Procédé et appareil pour inhiber la croissance de cellules ou de virus prolifératifs
KR102428203B1 (ko) * 2020-02-25 2022-08-04 서울대학교산학협력단 질병 치료를 위한 교류 자기장 발생 장치 및 시스템
WO2021221479A1 (fr) 2020-04-29 2021-11-04 S-Alpha Therapeutics, Inc. Dispositif numérique antiviral
CA3178883A1 (fr) 2020-06-30 2022-01-06 Novocure Gmbh Reseaux de transducteurs flexibles dotes d'une couche polymere isolante permettant l'application de champs de traitement des tumeurs (ttfields)
US20230355998A1 (en) * 2020-09-23 2023-11-09 Stimit Ag Stimulation device and method of stimulating a nerve
EP4217055A1 (fr) * 2020-09-23 2023-08-02 Stimit AG Dispositif de stimulation d'un nerf
EP4019076B1 (fr) * 2020-12-23 2022-11-16 Keytec GmbH Appareil d'électrothérapie de détermination des positions de l'appareil d'électrothérapie
CN113289246A (zh) * 2021-05-12 2021-08-24 上海捍宇医疗科技股份有限公司 用于临床的快速降低血压的经皮神经刺激装置
WO2022245878A1 (fr) 2021-05-17 2022-11-24 Setpoint Medical Corporation Système d'authentification et d'expiration de paramètre de neurostimulation pour neurostimulation
KR102556503B1 (ko) * 2021-08-17 2023-07-20 주식회사 뉴로티엑스 뇌파 및 심박신호를 활용한 신경자극 기반 뉴로피드백 장치
CN113730809B (zh) * 2021-10-09 2024-08-16 科悦医疗(苏州)有限公司 一种非侵入式迷走神经联合骶神经刺激装置
CN114404803A (zh) * 2022-01-05 2022-04-29 清华大学 迷走神经刺激仪及迷走神经刺激方法
US20250229086A1 (en) 2022-01-20 2025-07-17 Setpoint Medical Corporation Treatment of inflammatory disorders
CN115192907A (zh) * 2022-07-29 2022-10-18 北京理工大学 一种实时生物反馈经皮迷走神经电子针灸装置
TWI865976B (zh) * 2022-11-30 2024-12-11 國立彰化師範大學 電化學檢測誤差資料處理方法
KR102620746B1 (ko) * 2022-12-12 2024-01-05 김광희 탈부착형 초음파 및 저주파 핸드피스
WO2025105515A1 (fr) * 2023-11-14 2025-05-22 엘지전자 주식회사 Appareil de bio-stimulation
WO2025105516A1 (fr) * 2023-11-14 2025-05-22 엘지전자 주식회사 Dispositif de biostimulation
WO2025114455A1 (fr) * 2023-11-30 2025-06-05 Stimit Ag Dispositif de stimulation et procédé de stimulation d'un nerf phrénique
WO2025244305A1 (fr) * 2024-05-20 2025-11-27 주식회사 제이시스메디칼 Dispositif de sortie à haute fréquence
CN119909311B (zh) * 2024-12-27 2025-11-04 华南理工大学 一种无创深部耦合电刺激方法、装置、设备和存储介质

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US20130172957A1 (en) * 2011-12-28 2013-07-04 ElectroCore, LLC. Non-invasive nerve stimulator circuit
US20130238049A1 (en) * 2009-03-20 2013-09-12 ElectroCore, LLC Non-invasive vagal nerve stimulation to treat disorders

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US9126050B2 (en) * 2009-03-20 2015-09-08 ElectroCore, LLC Non-invasive vagus nerve stimulation devices and methods to treat or avert atrial fibrillation
EP1967226A1 (fr) * 2007-03-09 2008-09-10 Koninklijke Philips Electronics N.V. Neurostimulation transcutanée modulée audio
JP5117829B2 (ja) * 2007-11-22 2013-01-16 日本電信電話株式会社 筋緊張緩和装置
US10232178B2 (en) * 2009-03-20 2019-03-19 Electrocore, Inc. Non-invasive magnetic or electrical nerve stimulation to treat or prevent dementia
GB201001631D0 (en) * 2010-02-01 2010-03-17 Eumedic Ltd Treatment patch electrode for applying electrical impulses to the body of a patient

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WO2009064641A1 (fr) * 2007-11-16 2009-05-22 Ethicon, Inc. Timbres de stimulation de nerfs et méthodes de stimulation de nerfs sélectionnés
US20130238049A1 (en) * 2009-03-20 2013-09-12 ElectroCore, LLC Non-invasive vagal nerve stimulation to treat disorders
US20130172957A1 (en) * 2011-12-28 2013-07-04 ElectroCore, LLC. Non-invasive nerve stimulator circuit

Non-Patent Citations (1)

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Title
See also references of WO2015179744A1 *

Also Published As

Publication number Publication date
WO2015179744A1 (fr) 2015-11-26
JP6981752B2 (ja) 2021-12-17
EP3145584A1 (fr) 2017-03-29
CN106794347A (zh) 2017-05-31
KR20170028319A (ko) 2017-03-13
JP2017519549A (ja) 2017-07-20
EP3145584B1 (fr) 2022-02-16
CN106794347B (zh) 2020-01-17
KR102382416B1 (ko) 2022-04-01

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