EP3384015A4 - Skalierbare verfahren zur herstellung eines rekombinanten adeno-assoziierten viralen vektors in einem für die klinische anwendung geeigneten serumfreien suspensionszellkultursystem - Google Patents

Skalierbare verfahren zur herstellung eines rekombinanten adeno-assoziierten viralen vektors in einem für die klinische anwendung geeigneten serumfreien suspensionszellkultursystem Download PDF

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Publication number
EP3384015A4
EP3384015A4 EP16871497.0A EP16871497A EP3384015A4 EP 3384015 A4 EP3384015 A4 EP 3384015A4 EP 16871497 A EP16871497 A EP 16871497A EP 3384015 A4 EP3384015 A4 EP 3384015A4
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EP
European Patent Office
Prior art keywords
aav
serum
vector
cell culture
system suitable
Prior art date
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Pending
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EP16871497.0A
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English (en)
French (fr)
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EP3384015A1 (de
Inventor
Guang Qu
Lin Lu
John Fraser Wright
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Spark Therapeutics Inc
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Spark Therapeutics Inc
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Publication date
Application filed by Spark Therapeutics Inc filed Critical Spark Therapeutics Inc
Publication of EP3384015A1 publication Critical patent/EP3384015A1/de
Publication of EP3384015A4 publication Critical patent/EP3384015A4/de
Pending legal-status Critical Current

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    • C12N2750/14011—Parvoviridae
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
    • C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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EP16871497.0A 2015-12-01 2016-12-01 Skalierbare verfahren zur herstellung eines rekombinanten adeno-assoziierten viralen vektors in einem für die klinische anwendung geeigneten serumfreien suspensionszellkultursystem Pending EP3384015A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562261815P 2015-12-01 2015-12-01
PCT/US2016/064414 WO2017096039A1 (en) 2015-12-01 2016-12-01 Scalable methods for producing recombinant adeno-associated viral (aav) vector in serum-free suspension cell culture system suitable for clinical use

Publications (2)

Publication Number Publication Date
EP3384015A1 EP3384015A1 (de) 2018-10-10
EP3384015A4 true EP3384015A4 (de) 2019-05-29

Family

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EP16871497.0A Pending EP3384015A4 (de) 2015-12-01 2016-12-01 Skalierbare verfahren zur herstellung eines rekombinanten adeno-assoziierten viralen vektors in einem für die klinische anwendung geeigneten serumfreien suspensionszellkultursystem

Country Status (16)

Country Link
US (1) US20190292561A1 (de)
EP (1) EP3384015A4 (de)
JP (2) JP7444521B2 (de)
KR (1) KR20180091863A (de)
CN (1) CN108603174A (de)
AU (3) AU2016362317B2 (de)
CA (1) CA3006309A1 (de)
CO (1) CO2018006699A2 (de)
IL (1) IL259595B2 (de)
MX (2) MX2018006682A (de)
MY (1) MY205245A (de)
PE (2) PE20181534A1 (de)
PH (1) PH12018501168B1 (de)
RU (1) RU2766583C2 (de)
SG (2) SG11201804400SA (de)
WO (1) WO2017096039A1 (de)

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