EP3407909A4 - Traitement contre le cancer - Google Patents

Traitement contre le cancer Download PDF

Info

Publication number: EP3407909A4
Authority: EP; European Patent Office
Prior art keywords: against cancer; treatment against; treatment; cancer
Prior art date: 2016-01-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP17743494.1A

Other languages

German (de)

English (en)

Other versions

EP3407909B1 (fr

EP3407909A1 (fr

Inventor

Macarena PERAN

Julian Kenyon

Juan Antonio Marchal CORRALES

Maria Angel Garcia CHAVES

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Propanc Pty Ltd

Original Assignee

Propanc Pty Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-01-29

Filing date

2017-01-27

Publication date

2019-09-18

2017-01-27 Application filed by Propanc Pty Ltd filed Critical Propanc Pty Ltd

2018-12-05 Publication of EP3407909A1 publication Critical patent/EP3407909A1/fr

2019-09-18 Publication of EP3407909A4 publication Critical patent/EP3407909A4/fr

2023-08-09 Application granted granted Critical

2023-08-09 Publication of EP3407909B1 publication Critical patent/EP3407909B1/fr

Status Active legal-status Critical Current

2037-01-27 Anticipated expiration legal-status Critical

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21001—Chymotrypsin (3.4.21.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21004—Trypsin (3.4.21.4)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP17743494.1A 2016-01-29 2017-01-27 Traitement contre le cancer Active EP3407909B1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
ES201630112		2016-01-29
ES201631662		2016-12-22
PCT/AU2017/050065 WO2017127892A1 (fr)	2016-01-29	2017-01-27	Traitement contre le cancer

Publications (3)

Publication Number	Publication Date
EP3407909A1 EP3407909A1 (fr)	2018-12-05
EP3407909A4 true EP3407909A4 (fr)	2019-09-18
EP3407909B1 EP3407909B1 (fr)	2023-08-09

Family

ID=59396793

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP17743494.1A Active EP3407909B1 (fr)	2016-01-29	2017-01-27	Traitement contre le cancer

Country Status (14)

Country	Link
US (2)	US11376313B2 (fr)
EP (1)	EP3407909B1 (fr)
JP (1)	JP7058604B2 (fr)
CN (1)	CN108697771A (fr)
AU (1)	AU2017212151B2 (fr)
CA (1)	CA3012398A1 (fr)
DK (1)	DK3407909T5 (fr)
ES (1)	ES2965358T3 (fr)
HK (1)	HK1251794A1 (fr)
IL (1)	IL260814B2 (fr)
MY (1)	MY198500A (fr)
NZ (1)	NZ744845A (fr)
SG (1)	SG11201806318UA (fr)
WO (1)	WO2017127892A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN108697771A (zh)	2016-01-29	2018-10-23	普罗潘克股份有限公司	癌症治疗
US20190134166A1 (en)	2016-04-12	2019-05-09	Propanc Pty Ltd	Composition of proenzymes for cancer treatment
CN114848665B (zh) *	2022-06-22	2023-09-12	中南大学湘雅三医院	CD71-CD44-GEMs在制备治疗膀胱癌药物中的应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4514388A (en)	1983-03-22	1985-04-30	Psaledakis Nicholas G	Proteolytic enzymes in the zymogen form to treat sarcoma cells
US4978332A (en)	1987-09-28	1990-12-18	Matrix Pharmaceutical, Inc.	Treatments employing vasoconstrictive substances in combination with cytotoxic agents for introduction into cellular lesion areas
US5595756A (en)	1993-12-22	1997-01-21	Inex Pharmaceuticals Corporation	Liposomal compositions for enhanced retention of bioactive agents
CZ283972B6 (cs) *	1995-05-17	1998-07-15	František Mudr. Trnka	Farmaceutický prostředek s modulačním účinkem na zhoubné nádory a jeho použití
RU2149021C1 (ru)	1998-05-07	2000-05-20	Научный центр акушерства, гинекологии и перинатологии РАМН	Способ фармакологического лечения аутоиммунного мужского бесплодия
US6670330B1 (en)	2000-05-01	2003-12-30	Theodore J. Lampidis	Cancer chemotherapy with 2-deoxy-D-glucose
AU2002226650A1 (en)	2001-01-18	2002-07-30	Arnold Hoffman	Redox therapy for tumors
JP2004182674A (ja)	2002-12-05	2004-07-02	Kureha Chem Ind Co Ltd	バニリル脂肪酸アミドを含む抗腫瘍医薬組成物
WO2004062604A2 (fr)	2003-01-10	2004-07-29	Threshold Pharmaceuticals, Inc.	Traitement du cancer par le 2-desoxyglucose
WO2004103355A1 (fr)	2003-05-13	2004-12-02	Health Research Inc.	Procede pour augmenter l'activite antitumorale d'agents anticancereux
DE10321725A1 (de)	2003-05-14	2004-12-02	Mucos Pharma Gmbh & Co	Enzymhaltige Zusammensetzungen, daraus hergestellte diätetische Lebensmittel und Arzneimittel und ihre Verwendung für medizinische Zwecke
US20060093684A1 (en)	2004-10-28	2006-05-04	Iwao Takeda	Seleniferous composition for producing antioxidase in vivo
KR100740989B1 (ko)	2005-07-22	2007-07-19	넨시스(주)	구형 항염·항암효소 과립제 및 이의 제조방법
KR101058136B1 (ko)	2007-11-09	2011-08-24	신동헌	캡시에이트 또는 디하이드로캡시에이트의 신규한 용도
PT3095458T (pt) *	2009-10-22	2018-11-09	Propanc Pty Ltd	Composição farmacêutica para tratar cancro compreendendo tripsinogénio e quimiotripsinogénio
CZ307195B6 (cs) *	2013-11-18	2018-03-14	František Trnka	Farmaceutická kompozice obsahující směs proenzymů a enzymů
WO2016020572A1 (fr)	2014-08-04	2016-02-11	Universidad De Granada	Milieu de culture et procédé d'enrichissement et de maintien de cellules mères cancérigènes (csc) à l'aide dudit milieu
CN108697771A (zh)	2016-01-29	2018-10-23	普罗潘克股份有限公司	癌症治疗
US20190134166A1 (en)	2016-04-12	2019-05-09	Propanc Pty Ltd	Composition of proenzymes for cancer treatment

2017
- 2017-01-27 CN CN201780011674.3A patent/CN108697771A/zh active Pending
- 2017-01-27 JP JP2018539864A patent/JP7058604B2/ja active Active
- 2017-01-27 HK HK18116627.7A patent/HK1251794A1/zh unknown
- 2017-01-27 AU AU2017212151A patent/AU2017212151B2/en active Active
- 2017-01-27 DK DK17743494.1T patent/DK3407909T5/da active
- 2017-01-27 ES ES17743494T patent/ES2965358T3/es active Active
- 2017-01-27 IL IL260814A patent/IL260814B2/en unknown
- 2017-01-27 CA CA3012398A patent/CA3012398A1/fr active Pending
- 2017-01-27 NZ NZ744845A patent/NZ744845A/en unknown
- 2017-01-27 WO PCT/AU2017/050065 patent/WO2017127892A1/fr not_active Ceased
- 2017-01-27 SG SG11201806318UA patent/SG11201806318UA/en unknown
- 2017-01-27 EP EP17743494.1A patent/EP3407909B1/fr active Active
- 2017-01-27 MY MYPI2018702633A patent/MY198500A/en unknown
- 2017-01-27 US US16/073,247 patent/US11376313B2/en active Active
2022
- 2022-06-03 US US17/805,336 patent/US20230089740A1/en not_active Abandoned

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOSEF F NOVAK ET AL: "Trypsin/chymotrypsin and their respective zymogens inhibit tumor growth in vitro and in vivo", 1 January 2006 (2006-01-01), XP055610326, Retrieved from the Internet <URL:http://www.medicinabiomolecular.com.br/biblioteca/pdfs/Cancer/ca-3181.pdf> [retrieved on 20190801] *
MARTIN WALD ET AL: "Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16", 1 January 2001 (2001-01-01), XP055610314, Retrieved from the Internet <URL:https://link.springer.com/content/pdf/10.1007/s002800170004.pdf> [retrieved on 20190801] *

Also Published As

Publication number	Publication date
MY198500A (en)	2023-09-01
IL260814B (en)	2022-12-01
US20190038725A1 (en)	2019-02-07
DK3407909T3 (da)	2023-11-13
CA3012398A1 (fr)	2017-08-03
HK1251794A1 (zh)	2019-03-15
IL260814B2 (en)	2023-04-01
SG11201806318UA (en)	2018-08-30
WO2017127892A1 (fr)	2017-08-03
AU2017212151B2 (en)	2020-07-16
US20230089740A1 (en)	2023-03-23
US11376313B2 (en)	2022-07-05
IL260814A (en)	2018-10-31
ES2965358T3 (es)	2024-04-15
EP3407909B1 (fr)	2023-08-09
CN108697771A (zh)	2018-10-23
EP3407909A1 (fr)	2018-12-05
DK3407909T5 (da)	2024-09-23
AU2017212151A1 (en)	2018-08-16
JP2019507129A (ja)	2019-03-14
JP7058604B2 (ja)	2022-04-22
NZ744845A (en)	2023-04-28

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