EP3571290A4 - Milieux et procédés pour améliorer la survie et la prolifération de cellules souches - Google Patents

Milieux et procédés pour améliorer la survie et la prolifération de cellules souches Download PDF

Info

Publication number: EP3571290A4
Authority: EP; European Patent Office
Prior art keywords: survival; proliferation; media; increasing; methods
Prior art date: 2017-01-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP18741389.3A

Other languages

German (de)

English (en)

Other versions

EP3571290B1 (fr

EP3571290A1 (fr

Inventor

Adam HIRST

Melanie KARDEL

Wing CHANG

Michael Hiatt

Eric Jervis

Arwen HUNTER

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Stemcell Technologies Canada Inc

Original Assignee

Stemcell Technologies Canada Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-01-23

Filing date

2018-01-23

Publication date

2020-10-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=62907538&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP3571290(A4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2018-01-23 Application filed by Stemcell Technologies Canada Inc filed Critical Stemcell Technologies Canada Inc

2018-01-23 Priority to EP24162728.0A priority Critical patent/EP4361256A3/fr

2019-11-27 Publication of EP3571290A1 publication Critical patent/EP3571290A1/fr

2020-10-28 Publication of EP3571290A4 publication Critical patent/EP3571290A4/fr

2024-04-10 Application granted granted Critical

2024-04-10 Publication of EP3571290B1 publication Critical patent/EP3571290B1/fr

Status Active legal-status Critical Current

2038-01-23 Anticipated expiration legal-status Critical

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Organic Chemistry (AREA)
Biotechnology (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Developmental Biology & Embryology (AREA)
Microbiology (AREA)
Reproductive Health (AREA)
Cell Biology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Gynecology & Obstetrics (AREA)
Transplantation (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

EP18741389.3A 2017-01-23 2018-01-23 Milieux et procédés pour améliorer la survie et la prolifération de cellules souches Active EP3571290B1 (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
EP24162728.0A EP4361256A3 (fr)	2017-01-23	2018-01-23	Milieux et procédés pour améliorer la survie et la prolifération de cellules souches

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201762449413P	2017-01-23	2017-01-23
US201762518776P	2017-06-13	2017-06-13
US201762608875P	2017-12-21	2017-12-21
PCT/CA2018/050076 WO2018132926A1 (fr)	2017-01-23	2018-01-23	Milieux et procédés pour améliorer la survie et la prolifération de cellules souches

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
EP24162728.0A Division EP4361256A3 (fr)	2017-01-23	2018-01-23	Milieux et procédés pour améliorer la survie et la prolifération de cellules souches

Publications (3)

Publication Number	Publication Date
EP3571290A1 EP3571290A1 (fr)	2019-11-27
EP3571290A4 true EP3571290A4 (fr)	2020-10-28
EP3571290B1 EP3571290B1 (fr)	2024-04-10

Family

ID=62907538

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
EP18741389.3A Active EP3571290B1 (fr)	2017-01-23	2018-01-23	Milieux et procédés pour améliorer la survie et la prolifération de cellules souches
EP24162728.0A Pending EP4361256A3 (fr)	2017-01-23	2018-01-23	Milieux et procédés pour améliorer la survie et la prolifération de cellules souches

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
EP24162728.0A Pending EP4361256A3 (fr)	2017-01-23	2018-01-23	Milieux et procédés pour améliorer la survie et la prolifération de cellules souches

Country Status (9)

Country	Link
US (2)	US11697796B2 (fr)
EP (2)	EP3571290B1 (fr)
JP (1)	JP7049347B2 (fr)
CN (1)	CN110462025B (fr)
AU (1)	AU2018209127B2 (fr)
CA (1)	CA3051141C (fr)
IL (1)	IL268194B (fr)
SG (1)	SG11201906731XA (fr)
WO (1)	WO2018132926A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP7049347B2 (ja)	2017-01-23	2022-04-06	ステムセルテクノロジーズカナダインコーポレイテッド	幹細胞の生存および増殖を高めるための培地および方法
CN111808797A (zh) *	2020-07-28	2020-10-23	湖南赛诺生物科技股份有限公司	Necrostatin-1的应用及促进新生猪胰岛细胞成熟的制剂
JP2022032793A (ja) *	2020-08-14	2022-02-25	アルブキュラコーポレーション	アルブミン組成物並びにそれを製造及び使用する方法
EP4208177A1 (fr)	2020-09-02	2023-07-12	Yztherapeutic Performance Ltd.	Composition cellulaire pour le traitement de maladies, de troubles ou d'états et procédé d'utilisation
WO2022114724A1 (fr) *	2020-11-27	2022-06-02	(주)엑셀세라퓨틱스	Composition de milieu pour la production d'exosomes avec une efficacité élevée et une pureté élevée
CN116867892A (zh) *	2021-02-15	2023-10-10	凸版印刷株式会社	三维组织体的制造方法和脂肪来源干细胞的分化促进方法
CN116121186A (zh) *	2023-01-03	2023-05-16	内蒙古奥普赛生物科技有限公司	一种利用棕榈油酸培养脂肪间充质干细胞的方法
JP2026513626A (ja) *	2023-04-20	2026-04-28	ステムセルテクノロジーズカナダインコーポレイテッド	Ｐｓｃの大規模増殖のための方法
CN116814532B (zh) *	2023-07-10	2025-02-11	上海迈邦生物科技有限公司	一种用于哺乳动物细胞培养基的脂类复合物及其制备方法与应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20100279412A1 (en) *	2006-01-13	2010-11-04	Japan Science And Technology Agency	Culture medium additive for use in serum-free culturing of animal cell, kit and use thereof
CA2782296A1 (fr) *	2009-12-04	2011-06-09	Kristiina Rajala	Formulations et procedes de culture de cellules souches
WO2015042356A1 (fr) *	2013-09-19	2015-03-26	The United States Of America, As Represented By The Secretary, Department Of Health & Human Services	Milieu de culture chimiquement défini pour le maintien et la différenciation de cellules souches
US9399761B2 (en) *	2011-12-05	2016-07-26	Factor Bioscience Inc.	Methods of reprogramming cells to a less differentiated state
CA2981277A1 (fr) *	2015-03-30	2016-10-06	Ajinomoto Co., Inc.	Milieu de culture contenant une serum-albumine humaine pour la croissance de cellules souches neurales

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AU5734998A (en)	1997-01-10	1998-08-03	Life Technologies, Inc.	Embryonic stem cell serum replacement
BRPI0514778B1 (pt) *	2004-09-08	2018-07-10	Wisconsin Alumni Research Foundation	Meio para cultivar células tronco embrionárias
US8241908B2 (en) *	2006-05-16	2012-08-14	Becton, Dickinson And Company	Extracellular matrix coated surface for culturing cells
GB0613756D0 (en)	2006-07-12	2006-08-23	Univ Sheffield	Cell culture medium
ES2360782B1 (es)	2009-07-28	2012-03-12	Grifols, S.A.	Medios para cultivo de células de mamíferos que comprenden sobrenadante de etapas del fraccionamiento de Cohn y uso de los mismos.
EP2521628B1 (fr)	2010-01-06	2018-02-28	Ervin Industries, Inc.	Projectiles composites céramique-métal cassables et leurs procédés de fabrication
JP6148429B2 (ja)	2011-01-31	2017-06-14	協和発酵バイオ株式会社	ヒト多能性幹細胞の培養方法
CA2866590A1 (fr)	2012-03-07	2013-09-12	Janssen Biotech, Inc.	Milieux definis pour le developpement et la preservation des cellules souches pluripotentes
US10920192B2 (en) *	2013-04-23	2021-02-16	Yeda Research And Development Co. Ltd.	Isolated naive pluripotent stem cells and methods of generating same
CN105283541B (zh) *	2013-05-30	2019-02-19	味之素株式会社	干细胞培养用培养基
JP7049347B2 (ja)	2017-01-23	2022-04-06	ステムセルテクノロジーズカナダインコーポレイテッド	幹細胞の生存および増殖を高めるための培地および方法

2018
- 2018-01-23 JP JP2019539835A patent/JP7049347B2/ja active Active
- 2018-01-23 SG SG11201906731XA patent/SG11201906731XA/en unknown
- 2018-01-23 WO PCT/CA2018/050076 patent/WO2018132926A1/fr not_active Ceased
- 2018-01-23 EP EP18741389.3A patent/EP3571290B1/fr active Active
- 2018-01-23 AU AU2018209127A patent/AU2018209127B2/en active Active
- 2018-01-23 CA CA3051141A patent/CA3051141C/fr active Active
- 2018-01-23 CN CN201880019192.7A patent/CN110462025B/zh active Active
- 2018-01-23 US US16/480,025 patent/US11697796B2/en active Active
- 2018-01-23 EP EP24162728.0A patent/EP4361256A3/fr active Pending
2019
- 2019-07-21 IL IL268194A patent/IL268194B/en unknown
2023
- 2023-03-15 US US18/184,517 patent/US20230250392A1/en active Pending

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20100279412A1 (en) *	2006-01-13	2010-11-04	Japan Science And Technology Agency	Culture medium additive for use in serum-free culturing of animal cell, kit and use thereof
CA2782296A1 (fr) *	2009-12-04	2011-06-09	Kristiina Rajala	Formulations et procedes de culture de cellules souches
US9399761B2 (en) *	2011-12-05	2016-07-26	Factor Bioscience Inc.	Methods of reprogramming cells to a less differentiated state
WO2015042356A1 (fr) *	2013-09-19	2015-03-26	The United States Of America, As Represented By The Secretary, Department Of Health & Human Services	Milieu de culture chimiquement défini pour le maintien et la différenciation de cellules souches
CA2981277A1 (fr) *	2015-03-30	2016-10-06	Ajinomoto Co., Inc.	Milieu de culture contenant une serum-albumine humaine pour la croissance de cellules souches neurales

Non-Patent Citations (3)

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Title
GARCIA-GONZALO F R ET AL: "Albumin-Associated Lipids Regulate Human Embryonic Stem Cell Self-Renewal", PLOS ONE, PUBLIC LIBRARY OF SCIENCE, US, vol. 3, no. 1, 2 January 2008 (2008-01-02), pages 1 - 10, XP002548861, ISSN: 1932-6203, DOI: 10.1371/JOURNAL.PONE.0001384 *
HUI ZHANG ET AL: "Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions", CELL REPORTS, vol. 16, no. 6, 1 August 2016 (2016-08-01), US, pages 1536 - 1547, XP055731398, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2016.06.102 *
M. K. FURUE ET AL: "Heparin promotes the growth of human embryonic stem cells in a defined serum-free medium", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 105, no. 36, 9 September 2008 (2008-09-09), pages 13409 - 13414, XP055142731, ISSN: 0027-8424, DOI: 10.1073/pnas.0806136105 *

Also Published As

Publication number	Publication date
JP7049347B2 (ja)	2022-04-06
EP3571290B1 (fr)	2024-04-10
IL268194A (en)	2019-09-26
SG11201906731XA (en)	2019-08-27
IL268194B (en)	2022-05-01
AU2018209127B2 (en)	2021-10-21
US11697796B2 (en)	2023-07-11
JP2020505038A (ja)	2020-02-20
AU2018209127A1 (en)	2019-08-08
CA3051141A1 (fr)	2018-07-26
CN110462025A (zh)	2019-11-15
EP3571290A1 (fr)	2019-11-27
US20230250392A1 (en)	2023-08-10
WO2018132926A1 (fr)	2018-07-26
US20200017825A1 (en)	2020-01-16
CN110462025B (zh)	2023-11-21
EP4361256A2 (fr)	2024-05-01
EP4361256A3 (fr)	2024-07-31
CA3051141C (fr)	2021-06-22

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