EP3688449A4 - Nanoelektrodenvorrichtungen und verfahren zur herstellung davon - Google Patents

Nanoelektrodenvorrichtungen und verfahren zur herstellung davon Download PDF

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Publication number
EP3688449A4
EP3688449A4 EP18861291.5A EP18861291A EP3688449A4 EP 3688449 A4 EP3688449 A4 EP 3688449A4 EP 18861291 A EP18861291 A EP 18861291A EP 3688449 A4 EP3688449 A4 EP 3688449A4
Authority
EP
European Patent Office
Prior art keywords
nanoelectrode
fabrication
methods
devices
nanoelectrode devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18861291.5A
Other languages
English (en)
French (fr)
Other versions
EP3688449A1 (de
Inventor
Kazusuke MIHARA
Hisao Kawasaki
Valentin V. DIMITROV
Toshihiko HONKURA
Mark F. Oldham
Eric S. Nordman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quantum Biosystems Inc
Original Assignee
Quantum Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quantum Biosystems Inc filed Critical Quantum Biosystems Inc
Publication of EP3688449A1 publication Critical patent/EP3688449A1/de
Publication of EP3688449A4 publication Critical patent/EP3688449A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3278—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction involving nanosized elements, e.g. nanogaps or nanoparticles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
EP18861291.5A 2017-09-27 2018-09-27 Nanoelektrodenvorrichtungen und verfahren zur herstellung davon Withdrawn EP3688449A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762563859P 2017-09-27 2017-09-27
PCT/JP2018/036086 WO2019065904A1 (en) 2017-09-27 2018-09-27 NANOELECTRODES DEVICES AND METHODS OF MANUFACTURING THE SAME

Publications (2)

Publication Number Publication Date
EP3688449A1 EP3688449A1 (de) 2020-08-05
EP3688449A4 true EP3688449A4 (de) 2021-11-24

Family

ID=65901624

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18861291.5A Withdrawn EP3688449A4 (de) 2017-09-27 2018-09-27 Nanoelektrodenvorrichtungen und verfahren zur herstellung davon

Country Status (3)

Country Link
EP (1) EP3688449A4 (de)
TW (1) TW201928340A (de)
WO (1) WO2019065904A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9194838B2 (en) 2010-03-03 2015-11-24 Osaka University Method and device for identifying nucleotide, and method and device for determining nucleotide sequence of polynucleotide
EP3047282B1 (de) 2013-09-18 2019-05-15 Quantum Biosystems Inc. Biomolekülsequenzierungsvorrichtungen, -systeme und -verfahren
JP2015077652A (ja) 2013-10-16 2015-04-23 クオンタムバイオシステムズ株式会社 ナノギャップ電極およびその製造方法
US10438811B1 (en) 2014-04-15 2019-10-08 Quantum Biosystems Inc. Methods for forming nano-gap electrodes for use in nanosensors
WO2015170782A1 (en) 2014-05-08 2015-11-12 Osaka University Devices, systems and methods for linearization of polymers
KR20190075010A (ko) 2016-04-27 2019-06-28 퀀텀 바이오시스템즈 가부시키가이샤 생체분자의 측정 및 시퀀싱을 위한 시스템 및 방법
EP4673745A1 (de) * 2023-03-02 2026-01-07 Agency for Science, Technology and Research Nanogap-elektrodenvorrichtung, verfahren zur herstellung einer nanogap-elektrodenvorrichtung und sensor zum nachweis eines zielanalyten

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017189930A1 (en) * 2016-04-27 2017-11-02 Quantum Biosystems Inc. Systems and methods for measurement and sequencing of bio-molecules

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1417352A4 (de) * 2001-06-11 2006-11-08 Genorx Inc Elektronischer nachweis biologischer moleküle mittels dünnschichten
WO2008124706A2 (en) * 2007-04-06 2008-10-16 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Devices and methods for target molecule characterization
US8652779B2 (en) * 2010-04-09 2014-02-18 Pacific Biosciences Of California, Inc. Nanopore sequencing using charge blockade labels
KR102023754B1 (ko) * 2011-07-27 2019-09-20 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 생체분자 특성규명용 나노포어 센서
JP2013090576A (ja) * 2011-10-24 2013-05-16 Hitachi Ltd 核酸分析デバイス及びそれを用いた核酸分析装置
WO2013154999A2 (en) * 2012-04-09 2013-10-17 The Trustees Of Columbia University In The City Of New York Method of preparation of nanopore and uses thereof
US9551697B2 (en) * 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
JP6516000B2 (ja) * 2014-05-08 2019-05-22 国立大学法人大阪大学 異種材料を含むナノギャップ電極
CN107683337B (zh) * 2015-06-23 2021-10-22 深圳华大生命科学研究院 微孔电极及分析化学物质的方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017189930A1 (en) * 2016-04-27 2017-11-02 Quantum Biosystems Inc. Systems and methods for measurement and sequencing of bio-molecules

Also Published As

Publication number Publication date
WO2019065904A1 (en) 2019-04-04
TW201928340A (zh) 2019-07-16
EP3688449A1 (de) 2020-08-05

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Inventor name: OLDHAM, MARK F.

Inventor name: HONKURA, TOSHIHIKO

Inventor name: DIMITROV, VALENTIN V.

Inventor name: MIHARA, KAZUSUKE

Inventor name: KAWASAKI, HISAO

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