EP3790876C0 - Depsipeptides endoparasitaires - Google Patents

Depsipeptides endoparasitaires

Info

Publication number
EP3790876C0
EP3790876C0 EP19725528.4A EP19725528A EP3790876C0 EP 3790876 C0 EP3790876 C0 EP 3790876C0 EP 19725528 A EP19725528 A EP 19725528A EP 3790876 C0 EP3790876 C0 EP 3790876C0
Authority
EP
European Patent Office
Prior art keywords
depsipeptids
endoparasitic
endoparasitic depsipeptids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP19725528.4A
Other languages
German (de)
English (en)
Other versions
EP3790876A1 (fr
EP3790876B1 (fr
Inventor
Todd Maddux
Matthew W Bedore
Paul D Johnson
Tomasz Respondek
Susan M K Sheehan
Graham M Kyne
Richard Andrew Ewin
Rajendran Vairagoundar
Michael P Curtis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zoetis Services LLC
Original Assignee
Zoetis Services LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services LLC filed Critical Zoetis Services LLC
Publication of EP3790876A1 publication Critical patent/EP3790876A1/fr
Application granted granted Critical
Publication of EP3790876B1 publication Critical patent/EP3790876B1/fr
Publication of EP3790876C0 publication Critical patent/EP3790876C0/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EP19725528.4A 2018-05-10 2019-05-07 Depsipeptides endoparasitaires Active EP3790876B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862669623P 2018-05-10 2018-05-10
PCT/US2019/031158 WO2019217449A1 (fr) 2018-05-10 2019-05-07 Depsipeptides endoparasitaires

Publications (3)

Publication Number Publication Date
EP3790876A1 EP3790876A1 (fr) 2021-03-17
EP3790876B1 EP3790876B1 (fr) 2025-04-30
EP3790876C0 true EP3790876C0 (fr) 2025-04-30

Family

ID=66625336

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19725528.4A Active EP3790876B1 (fr) 2018-05-10 2019-05-07 Depsipeptides endoparasitaires

Country Status (15)

Country Link
US (1) US11771738B2 (fr)
EP (1) EP3790876B1 (fr)
JP (1) JP7260564B2 (fr)
KR (1) KR20210005176A (fr)
CN (1) CN112384511B (fr)
AU (1) AU2019266197B2 (fr)
BR (1) BR112020022925A2 (fr)
CA (1) CA3098151C (fr)
ES (1) ES3030701T3 (fr)
HU (1) HUE071406T2 (fr)
MX (1) MX2020011980A (fr)
NZ (1) NZ769696A (fr)
PL (1) PL3790876T3 (fr)
SG (1) SG11202010187RA (fr)
WO (1) WO2019217449A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4538282A1 (fr) * 2023-10-13 2025-04-16 Vetoquinol SA Synthèse d'emodepside
WO2025149943A1 (fr) * 2024-01-09 2025-07-17 Animol Discovery, Inc. Depsipeptides cycliques antiparasitaires

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO176766C (no) 1989-02-07 1995-05-24 Meiji Seika Kaisha Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet
CA2132199C (fr) 1992-03-17 2000-01-18 Hitoshi Nishiyama Derive depsipeptidique, production et application
CN1073560C (zh) 1993-02-19 2001-10-24 明治制果株式会社 环缩酚酸肽pf1022衍生物
DE4317457A1 (de) 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
DE4317432A1 (de) 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
US5646244A (en) 1993-09-06 1997-07-08 Fujisawa Pharmaceutical Co., Ltd. Cyclodepsipeptide compound
DE4437198A1 (de) 1994-10-18 1996-04-25 Bayer Ag Verfahren zur Sulfonylierung, Sulfenylierung und Phosphorylierung von cyclischen Depsipeptiden
US5763221A (en) 1995-06-22 1998-06-09 Meiji Seika Kaisha, Ltd. Transformant producing substance PF1022, and method for transforming microorganism belonging to the class hyphomycetes
CN1071323C (zh) 1995-06-30 2001-09-19 藤泽药品工业株式会社 缩肽衍生物或其盐的制造方法
NZ318515A (en) 1995-09-22 2000-05-26 Bayer Ag Cyclodepsipeptide PF1022 derivatives and compositions thereof
DE19545639A1 (de) 1995-12-07 1997-06-12 Bayer Ag Verfahren zur Herstellung von substituierten Arylmilchsäure-haltigen Cyclodepsipeptiden mit 24 Ringatomen
CN1076349C (zh) 1997-06-04 2001-12-19 拜尔公司 去氧环缩肽及其防治体内寄生虫的用途
DE19811559A1 (de) 1998-03-17 1999-09-23 Bayer Ag Cyclooctadepsipeptide
DE19828043A1 (de) * 1998-06-24 1999-12-30 Bayer Ag Ektoparasitizide Mittel
ATE484508T1 (de) 2002-04-18 2010-10-15 Astrazeneca Ab Furylverbindungen
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
WO2012177714A1 (fr) 2011-06-22 2012-12-27 Takeda Pharmaceutical Company Limited Dérivés de 6-aza-isoindolin-1-one substitués
CN107835818B (zh) 2015-05-20 2022-04-29 勃林格殷格翰动物保健美国公司 驱虫缩酚酸肽化合物
JP7164608B2 (ja) * 2017-11-29 2022-11-01 ゾエティス・サービシーズ・エルエルシー 内部寄生性デプシペプチド

Also Published As

Publication number Publication date
HUE071406T2 (hu) 2025-08-28
CN112384511B (zh) 2024-01-30
CN112384511A (zh) 2021-02-19
PL3790876T3 (pl) 2025-08-04
EP3790876A1 (fr) 2021-03-17
AU2019266197B2 (en) 2023-03-02
KR20210005176A (ko) 2021-01-13
JP2021524843A (ja) 2021-09-16
SG11202010187RA (en) 2020-11-27
NZ769696A (en) 2023-12-22
WO2019217449A1 (fr) 2019-11-14
MX2020011980A (es) 2021-03-26
BR112020022925A2 (pt) 2021-02-02
US11771738B2 (en) 2023-10-03
CA3098151A1 (fr) 2019-11-14
EP3790876B1 (fr) 2025-04-30
CA3098151C (fr) 2023-08-22
ES3030701T3 (en) 2025-07-01
JP7260564B2 (ja) 2023-04-18
US20220323540A1 (en) 2022-10-13
AU2019266197A1 (en) 2020-11-12

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