EP3978005A4 - Zusammensetzung zur vorbeugung, linderung oder behandlung des metabolischen syndroms, begleitet von adipositas und/oder diabetes, mit, als wirkstoff, einem komplex (ib-komplex) aus amlabaumextrakt und extrakt von gekeimter gerste - Google Patents

Zusammensetzung zur vorbeugung, linderung oder behandlung des metabolischen syndroms, begleitet von adipositas und/oder diabetes, mit, als wirkstoff, einem komplex (ib-komplex) aus amlabaumextrakt und extrakt von gekeimter gerste Download PDF

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Publication number
EP3978005A4
EP3978005A4 EP20815311.4A EP20815311A EP3978005A4 EP 3978005 A4 EP3978005 A4 EP 3978005A4 EP 20815311 A EP20815311 A EP 20815311A EP 3978005 A4 EP3978005 A4 EP 3978005A4
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Prior art keywords
complex
obesity
diabetes
relief
prevention
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Granted
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EP20815311.4A
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English (en)
French (fr)
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EP3978005A1 (de
EP3978005B1 (de
Inventor
Hae-Yeon Lee
Jong-Lae Kim
Tae-Gi Kim
Mi-Ryeong PARK
Jong-Wook Lee
Jin-Seong Yang
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Hlscience Co Ltd
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Hlscience Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/068Chewing gum characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/12Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52Adding ingredients
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03Organic compounds
    • A23L29/035Organic compounds containing oxygen as heteroatom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/328Foods, ingredients or supplements having a functional effect on health having effect on glycaemic control and diabetes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/332Promoters of weight control and weight loss
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00Food ingredients
    • A23V2250/20Natural extracts
    • A23V2250/21Plant extracts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00Food ingredients
    • A23V2250/30Other Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP20815311.4A 2019-05-30 2020-05-19 Zusammensetzung zur verwendung in der vorbeugung, linderung oder behandlung des metabolischen syndroms, begleitet von adipositas und/oder diabetes, mit, als wirkstoff, einem komplex (ib-komplex) aus amlabaumextrakt und extrakt von gekeimter gerste Active EP3978005B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20190064098 2019-05-30
PCT/KR2020/006545 WO2020242113A1 (ko) 2019-05-30 2020-05-19 인디안구스베리 추출물과 새싹보리 추출물의 복합물(ib복합물)을 유효성분으로 포함하는 비만 및/또는 당뇨를 동반하는 대사증후군의 예방, 개선 치료용 조성물

Publications (3)

Publication Number Publication Date
EP3978005A1 EP3978005A1 (de) 2022-04-06
EP3978005A4 true EP3978005A4 (de) 2023-03-15
EP3978005B1 EP3978005B1 (de) 2024-05-15

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EP20815311.4A Active EP3978005B1 (de) 2019-05-30 2020-05-19 Zusammensetzung zur verwendung in der vorbeugung, linderung oder behandlung des metabolischen syndroms, begleitet von adipositas und/oder diabetes, mit, als wirkstoff, einem komplex (ib-komplex) aus amlabaumextrakt und extrakt von gekeimter gerste

Country Status (7)

Country Link
US (1) US12403172B2 (de)
EP (1) EP3978005B1 (de)
JP (1) JP7303582B2 (de)
KR (1) KR102378396B1 (de)
CN (1) CN114007631B (de)
TW (1) TWI733458B (de)
WO (1) WO2020242113A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102751170B1 (ko) 2021-10-06 2025-01-09 주식회사 에이치엘사이언스 인디안구스베리 추출물 및 새싹보리 추출물의 복합물(ib복합물)을 유효성분으로 포함하는 항노화 피부 개선용 조성물
KR102705253B1 (ko) 2022-06-09 2024-09-11 주식회사 맨드림 식물 복합추출물을 유효성분으로 포함하는 두피 및 모발개선용 화장료 조성물
CN119909105A (zh) * 2025-04-02 2025-05-02 合生元(广州)健康产品有限公司 一种用于降脂降糖的营养组合物及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150130128A (ko) * 2014-05-13 2015-11-23 대한민국(농촌진흥청장) 새싹보리 추출물을 포함하는 비만 억제용 조성물
CN103736071B (zh) * 2014-01-23 2016-05-11 西藏金哈达药业有限公司 一种具有辅助降血糖功效的组合物及其应用、制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006008526A (ja) 2004-06-22 2006-01-12 Taiyo Kagaku Co Ltd 生活習慣病予防・改善組成物
JP2006056836A (ja) 2004-08-20 2006-03-02 Taiyo Kagaku Co Ltd 脂肪組織特異分泌蛋白産生増強組成物
JP2006104094A (ja) 2004-10-01 2006-04-20 Taiyo Kagaku Co Ltd α−グルコシダーゼ阻害剤
JP2008050301A (ja) 2006-08-24 2008-03-06 Prima Meat Packers Ltd 膵リパーゼ阻害剤
JP2008247871A (ja) 2007-03-30 2008-10-16 Taiyo Kagaku Co Ltd 内臓脂肪蓄積抑制組成物
JP2010202634A (ja) * 2008-06-05 2010-09-16 Green Kanpo Seiyaku Kk 生薬含有組成物及びその利用
JP4493725B1 (ja) 2009-10-02 2010-06-30 株式会社 ファイナルフューチャーインターナショナル 脂肪分解促進作用を有する組成物
JP6043923B2 (ja) 2010-12-08 2016-12-14 株式会社東洋新薬 食事摂取に伴う血中中性脂肪上昇抑制剤
KR20140127003A (ko) * 2013-04-24 2014-11-03 대한민국(농촌진흥청장) 새싹보리 지상부 추출물을 유효성분으로 포함하는 비만 또는 지질대사 질환의 예방, 치료 또는 개선용 조성물 및 추출물 제조방법
FR3027228B1 (fr) 2014-10-20 2016-12-09 Valbiotis Composition comprenant un melange d'extraits vegetaux et utilisation pour agir sur le metabolisme glucidique et/ou lipidique
JP2015127339A (ja) 2015-03-26 2015-07-09 株式会社東洋新薬 抗糖化用組成物
JP5910901B1 (ja) 2015-03-27 2016-04-27 株式会社東洋新薬 Glp−1分泌促進剤
CN105146655A (zh) 2015-09-07 2015-12-16 王保红 含有茶树花的饮品组合物及其制备方法和应用
JP2017105728A (ja) 2015-12-10 2017-06-15 株式会社東洋新薬 血糖値上昇抑制剤及び整腸剤
KR20180003073A (ko) 2016-06-30 2018-01-09 재단법인 전남생물산업진흥원 새싹보리 추출물을 포함하는 비만 치료 또는 예방용 조성물
CN106605822A (zh) 2016-12-19 2017-05-03 西安源森生物科技有限公司 一种有利于降血糖的组合物及其制备方法
KR101830048B1 (ko) 2017-09-08 2018-02-19 주식회사 프롬바이오 가자나무열매추출물 및 암라추출물을 포함하는 비만 또는 고지혈증 개선용 식품 조성물
KR20190064098A (ko) 2017-11-30 2019-06-10 에스케이하이닉스 주식회사 반도체 장치, 및 그의 리페어 동작방법

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103736071B (zh) * 2014-01-23 2016-05-11 西藏金哈达药业有限公司 一种具有辅助降血糖功效的组合物及其应用、制备方法
KR20150130128A (ko) * 2014-05-13 2015-11-23 대한민국(농촌진흥청장) 새싹보리 추출물을 포함하는 비만 억제용 조성물

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
"Abstracts of The 47th Annual Conference of Research Society for the Study of Diabetes in India", INTERNATIONAL JOURNAL OF DIABETES IN DEVELOPING COUNTRIES, SPRINGER (INDIA) PRIVATE LTD, INDIA, vol. 39, no. Suppl 1, 1 November 2019 (2019-11-01), pages 1 - 42, XP036925362, ISSN: 0973-3930, [retrieved on 20191101], DOI: 10.1007/S13410-019-00782-7 *
"Medoharayogah - 2", 1 January 2000, India, article ANONYMOUS: "Medoharayogah - 2", pages: 1 - 3, XP093019030 *
AHMED M ET AL: "PHYTOCHEMICAL SCREENING, TOTAL PHENOLIC AND FLAVONOIDS CONTENTS AND ANTIOXIDANT ACTIVITIES OF CITRULLUS COLOCYNTHIS L. AND CANNABIS SATIVA L.", APPLIED ECOLOGY AND ENVIRONMENTAL RESEARCH, vol. 17, no. 3, 8 October 2019 (2019-10-08), pages 1 - 19, XP055862116, ISSN: 1589-1623, Retrieved from the Internet <URL:https://www.epa.hu/02500/02583/00059/pdf/EPA02583_applied_ecology_2019_3_69616979.pdf> DOI: 10.15666/aeer/1703_69616979 *
ALTIOK E ET AL: "Isolation of polyphenols from the extracts of olive leaves (Olea europaea L.) by adsorption on silk fibroin", SEPARATION AND PURIFICATION TECHNOLOGY, ELSEVIER SCIENCE, AMSTERDAM, NL, vol. 62, no. 2, 1 September 2008 (2008-09-01), pages 342 - 348, XP022758139, ISSN: 1383-5866, [retrieved on 20080202], DOI: 10.1016/J.SEPPUR.2008.01.022 *
BYADGI PARAMESWARAPPAS ET AL: "Clinical assessment of dietary interventions and lifestyle modifications in Madhumeha (type- 2 Diabetes Mellitus)", AYU (MUMBAI), vol. 35, no. 4, 1 January 2014 (2014-01-01), IN, pages 391, XP093019041, ISSN: 0974-8520, Retrieved from the Internet <URL:https://www.ayujournal.org/temp/Ayu354391-5416723_150247.pdf> DOI: 10.4103/0974-8520.158997 *
D'SOUZA JASON JEROME ET AL: "Anti-diabetic effects of the Indian indigenous fruit Emblica officinalis Gaertn: active constituents and modes of action", FOOD & FUNCTION, vol. 5, no. 4, 1 January 2014 (2014-01-01), GB, pages 635, XP093019347, ISSN: 2042-6496, Retrieved from the Internet <URL:https://pubs.rsc.org/en/content/articlepdf/2014/fo/c3fo60366k> DOI: 10.1039/c3fo60366k *
FATIMA NOOR ET AL: "Ellagic acid inEmblica officinalisexerts anti-diabetic activity through the action on [beta]-cells of pancreas", EUROPEAN JOURNAL OF NUTRITION, STEINKOPFF VERLAG, DARMSTADT, DE, vol. 56, no. 2, 22 November 2015 (2015-11-22), pages 591 - 601, XP036182925, ISSN: 1436-6207, [retrieved on 20151122], DOI: 10.1007/S00394-015-1103-Y *
See also references of WO2020242113A1 *
YAWEN ZENG ET AL: "Preventive and Therapeutic Role of Functional Ingredients of Barley Grass for Chronic Diseases in Human Beings", OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, vol. 2018, 1 January 2018 (2018-01-01), US, pages 1 - 15, XP055703281, ISSN: 1942-0900, DOI: 10.1155/2018/3232080 *

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TW202106178A (zh) 2021-02-16
KR20200138003A (ko) 2020-12-09
US20220226421A1 (en) 2022-07-21
CN114007631A (zh) 2022-02-01
WO2020242113A1 (ko) 2020-12-03
EP3978005A1 (de) 2022-04-06
JP7303582B2 (ja) 2023-07-05
EP3978005B1 (de) 2024-05-15
KR102378396B1 (ko) 2022-03-24
TWI733458B (zh) 2021-07-11
US12403172B2 (en) 2025-09-02
JP2022535353A (ja) 2022-08-08

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