EP4084801A4 - Nouvelle formulation viscoélastique pour le traitement de l'arthrose et son procédé de production - Google Patents

Nouvelle formulation viscoélastique pour le traitement de l'arthrose et son procédé de production Download PDF

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Publication number
EP4084801A4
EP4084801A4 EP20910352.2A EP20910352A EP4084801A4 EP 4084801 A4 EP4084801 A4 EP 4084801A4 EP 20910352 A EP20910352 A EP 20910352A EP 4084801 A4 EP4084801 A4 EP 4084801A4
Authority
EP
European Patent Office
Prior art keywords
production method
osteoarthritis treatment
novel viscoelastic
viscoelastic formulation
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20910352.2A
Other languages
German (de)
English (en)
Other versions
EP4084801A1 (fr
Inventor
Faruk OYTUN
Busra Gizem KAYA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VSY Biyoteknoloji ve Ilac Sanayi AS
Original Assignee
VSY Biyoteknoloji ve Ilac Sanayi AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VSY Biyoteknoloji ve Ilac Sanayi AS filed Critical VSY Biyoteknoloji ve Ilac Sanayi AS
Publication of EP4084801A1 publication Critical patent/EP4084801A1/fr
Publication of EP4084801A4 publication Critical patent/EP4084801A4/fr
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/02Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075Macromolecular gels
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Materials Engineering (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP20910352.2A 2019-12-31 2020-12-31 Nouvelle formulation viscoélastique pour le traitement de l'arthrose et son procédé de production Pending EP4084801A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2019/22907A TR201922907A2 (tr) 2019-12-31 2019-12-31 Osteoartri̇t tedavi̇si̇ i̇çi̇n yeni̇ bi̇r vi̇skoelasti̇k formülasyonu ve bunun üreti̇m yöntemi̇
PCT/TR2020/051471 WO2021137837A1 (fr) 2019-12-31 2020-12-31 Nouvelle formulation viscoélastique pour le traitement de l'arthrose et son procédé de production

Publications (2)

Publication Number Publication Date
EP4084801A1 EP4084801A1 (fr) 2022-11-09
EP4084801A4 true EP4084801A4 (fr) 2024-04-17

Family

ID=76687210

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20910352.2A Pending EP4084801A4 (fr) 2019-12-31 2020-12-31 Nouvelle formulation viscoélastique pour le traitement de l'arthrose et son procédé de production

Country Status (3)

Country Link
EP (1) EP4084801A4 (fr)
TR (2) TR201922945A2 (fr)
WO (1) WO2021137837A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116919982A (zh) * 2022-04-07 2023-10-24 北京瑞熙天成生物科技有限公司 一种用于治疗关节炎的药物组合物及其应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090143331A1 (en) * 2007-11-30 2009-06-04 Dimitrios Stroumpoulis Polysaccharide gel formulation having increased longevity
US20130136780A1 (en) * 2007-11-30 2013-05-30 Allergan, Inc. Crosslinked polysaccharide gel compositions for medical and cosmetic applications
EP3257549A1 (fr) * 2015-02-13 2017-12-20 Endo Derma Co., Ltd. Microstructure à l'aide d'hydrogel d'acide hyaluronique réticulé, et son procédé de production
KR20180035032A (ko) * 2016-09-28 2018-04-05 주식회사 파마리서치프로덕트 가교 히알루론산을 포함하는 주사용 조성물
EP3473242A1 (fr) * 2016-06-16 2019-04-24 Endo Derma Co., Ltd. Microstructure d'acide hyaluronique présentant d'excellentes caractéristiques de solubilité

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827937A (en) * 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
ITPD20120098A1 (it) * 2012-03-30 2013-10-01 Fidia Farmaceutici "nuove formulazioni faramaceutiche contenenti condroitin solfato e derivati dell'acido ialuronico"
KR101459070B1 (ko) * 2013-12-09 2014-11-17 (주) 뉴메딕 지속성을 갖는 히알루론산 겔 조성물

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090143331A1 (en) * 2007-11-30 2009-06-04 Dimitrios Stroumpoulis Polysaccharide gel formulation having increased longevity
US20130136780A1 (en) * 2007-11-30 2013-05-30 Allergan, Inc. Crosslinked polysaccharide gel compositions for medical and cosmetic applications
EP3257549A1 (fr) * 2015-02-13 2017-12-20 Endo Derma Co., Ltd. Microstructure à l'aide d'hydrogel d'acide hyaluronique réticulé, et son procédé de production
EP3473242A1 (fr) * 2016-06-16 2019-04-24 Endo Derma Co., Ltd. Microstructure d'acide hyaluronique présentant d'excellentes caractéristiques de solubilité
KR20180035032A (ko) * 2016-09-28 2018-04-05 주식회사 파마리서치프로덕트 가교 히알루론산을 포함하는 주사용 조성물

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2021137837A1 *

Also Published As

Publication number Publication date
TR201922945A2 (tr) 2021-07-26
EP4084801A1 (fr) 2022-11-09
TR201922907A2 (tr) 2021-07-26
WO2021137837A1 (fr) 2021-07-08

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